The effect of whole body vibration on oxygen uptake and electromyographic signal of the rectus femoris muscle during static and dynamic squat

Whole Body Vibrations consist of a vibration stimulus mechanically transferred to the body. The impact of vibration treatment on specific muscular activity, neuromuscular, and postural control has been widely studied. We investigated whole body vibration (WBV) effect on oxygen uptake and electromyographic signal of the rectus femoris muscle during static and dynamic squat. Fourteen healthy subjects performed a static and dynamic squat with and without vibration. During the vibration exercises, a significant increase was found in oxygen uptake (P=0.05), which increased by 44% during the static squat and 29.4% during the dynamic squat. Vibration increased heart rate by 11.1 ± 9.1 beats.min-1 during the static squat and 7.9 ± 8.3 beats.min-1 during the dynamic squat. No significant changes were observed in rate of perceived exertion between the exercises with and without vibration. The results indicate that the static squat with WBV produced higher neuromuscular and cardiorespiratory system activation for exercise duration ?60 sec. Otherwise, if the single bout duration was higher than 60 sec, the greater cardiorespiratory system activation was achieved during the dynamic squat with WBV while higher neuromuscular activation was still obtained with the static exercise.

Internet of Things collaborativo: progettazione ed analisi di una piattaforma di aggregazione di dati sensoristici

Internet ha rivoluzionato il modo di comunicare degli individui. Siamo testimoni della nascita e dello sviluppo di un'era caratterizzata dalla disponibilità di informazione libera e accessibile a tutti. Negli ultimi anni grazie alla diffusione di smartphone, tablet e altre tipologie di dispositivi connessi, è cambiato il fulcro dell'innovazione spostandosi dalle persone agli oggetti. E' così che nasce il concetto di Internet of Things, termine usato per descrivere la rete di comunicazione creata tra i diversi dispositivi connessi ad Internet e capaci di interagire in autonomia. Gli ambiti applicativi dell'Internet of Things spaziano dalla domotica alla sanità, dall'environmental monitoring al concetto di smart cities e così via. L'obiettivo principale di tale disciplina è quello di migliorare la vita delle persone grazie a sistemi che siano in grado di interagire senza aver bisogno dell'intervento dell'essere umano. Proprio per la natura eterogenea della disciplina e in relazione ai diversi ambiti applicativi, nell'Internet of Things si può incorrere in problemi derivanti dalla presenza di tecnologie differenti o di modalità eterogenee di memorizzazione dei dati. A questo proposito viene introdotto il concetto di Internet of Things collaborativo, termine che indica l'obiettivo di realizzare applicazioni che possano garantire interoperabilità tra i diversi ecosistemi e tra le diverse fonti da cui l'Internet of Things attinge, sfruttando la presenza di piattaforme di pubblicazione di Open Data. L'obiettivo di questa tesi è stato quello di creare un sistema per l'aggregazione di dati da due piattaforme, ThingSpeak e Sparkfun, con lo scopo di unificarli in un unico database ed estrarre informazioni significative dai dati tramite due tecniche di Data Mining: il Dictionary Learning e l'Affinity Propagation. Vengono illustrate le due metodologie che rientrano rispettivamente tra le tecniche di classificazione e di clustering.

Progettazione e sviluppo di un' applicazione mobile basata su Wi-Fi Direct per la comunicazione tra veicoli e pedoni

Questo documento di tesi si incentra principalmente sullo studio delle reti wireless mobili e dei relativi scenari di utilizzo. In particolare, come esse vengono applicate per il riconoscimento e la prevenzione di incidenti stradali. Vista l’importanza di questo problema a livello di sicurezza stradale, ho deciso di sviluppare un' applicazione per smartphone Android, in grado di riconoscere le attività di uso quotidiano dell’utente e associarle a dei comportamenti, come ad esempio quello di un ciclista, di un pedone o di un automobilista. Nel caso in cui, in uno scenario stradale i dispositivi si trovassero ad una distanza ravvicinata, possono comunicare tramite una connessione Wi-Fi Direct il loro ruolo e lanciare messaggi di pericolo per avvisare la loro presenza, in modo da prevenire collisioni stradali. La realtà in cui si vuole collocare questa applicazione è quella che viene chiamata Pedestrian Detection, già idea di General Motors, che la sta sviluppando sui futuri veicoli che metterà in produzione nei prossimi anni e che sicuramente integreranno funzionalità aggiuntive per la segnalazione di pericoli tramite smartphone e Wi-Fi Direct.

Implementazione e valutazione delle prestazioni di algoritmi di localizzazione Indoor basati su dispositivi Beacon

Questo elaborato di tesi ha lo scopo di illustrare un'applicazione realizzata per dispositivi Android in grado di localizzare l'utente all'interno di un ambiente indoor sfruttando l'utilizzo dei Beacon e dare una valutazione dei risultati ottenuti. L'utente potrà registrare i dispositivi Beacon in suo possesso all'interno dell'applicazione, caricare la planimetria di un ambiente e configurarlo indicando esattamente quale Beacon si trova in una determinata posizione. Infine potrà scegliere quale tra i tre algoritmi implementati (Prossimità, Triangolazione e Fingerprinting) utilizzare per visualizzare la propria posizione sulla mappa. I tre algoritmi sono stati sottoposti a vari test che hanno permesso di analizzare le differenze tra di essi in termini di accuratezza e le performance generali dell'applicativo.

Progettazione ed analisi di algoritmi di mobilità controllata per reti mesh aeree con vincoli di copertura e persistenza

In questo lavoro di tesi verrà presentata l’implementazione di due algoritmi di Deployment e gestione di uno sciame di dispositivi UAV (Unmanned Aerial Vehicles). L’interesse scientifico su cui si fonda quest'analisi ha origine nelle enormi potenzialità degli UAV che garantiscono un'esplorazione aerea di aree pericolose in contesti di emergenze quali ad esempio scenari post catastrofe. La problematica principale affrontata sarà quella della gestione continuativa dell'area disastrata fornendo un algoritmo di schedulazione della cooperazione degli UAV alternando periodi attivi con quelli di ricarica dei dispositivi.

Marinetti y el modelo de artista moderno

El objetivo de este artículo es analizar la figura del artista a comienzos del siglo XX a través de los textos y las ideas del poeta italiano Filippo Tommaso Marinetti. Partiendo sus teorías de las bases del decadentismo, Marinetti genera un modelo de artista en el que ejercen gran influencia conceptos como el genio y la libertad artística, muy asociados al Romanticismo, pero al que añade nuevos elementos de gran relevancia para la coyuntura política y social de su época. Entre estos, estarían aquellos que vincularon al artista futurista con la política de su tiempo, con el fascismo y con los modos de comunicación con el cada vez más importante público de grandes masas. Obsesionado con la idea de progreso, Marinetti aspira a crear un nuevo artista capaz de generar un nuevo mundo que introdujera definitivamente a Italia en la modernidad.

Turandot in Schiller’s and Brecht’s Dramas

This paper aims to study the subject of Turandot in Friedrich Schiller’s Turandot, Prinzessin von China and Brecht’s Turandot oder Der Kongress der Weißwäscher. We will analyse both theatre adaptations, which have clearly influenced numerous authors through history, by addressing its intertextuality and originality.

Of Marx and Makers: an Historical Perspective on Generative Justice

In Marxist frameworks “distributive justice” depends on extracting value through a centralized state. Many new social movements—peer to peer economy, maker activism, community agriculture, queer ecology, etc.—take the opposite approach, keeping value in its unalienated form and allowing it to freely circulate from the bottom up. Unlike Marxism, there is no general theory for bottom-up, unalienated value circulation. This paper examines the concept of “generative justice” through an historical contrast between Marx’s writings and the indigenous cultures that he drew upon. Marx erroneously concluded that while indigenous cultures had unalienated forms of production, only centralized value extraction could allow the productivity needed for a high quality of life. To the contrary, indigenous cultures now provide a robust model for the “gift economy” that underpins open source technological production, agroecology, and restorative approaches to civil rights. Expanding Marx’s concept of unalienated labor value to include unalienated ecological (nonhuman) value, as well as the domain of freedom in speech, sexual orientation, spirituality and other forms of “expressive” value, we arrive at an historically informed perspective for generative justice. 

"Proposta di traduzione: Los Gatos del Papel di Enrique Pérez Díaz"

Il lavoro svolto è stato incentrato sulla traduzione dell’opera Los gatos del papel (2005) dell’autore cubano Enrique Pérez Díaz, una breve raccolta di racconti per bambini con protagonisti i gatti. Il valore e il significato che ha avuto per me questa esperienza di traduzione de Los gatos del papel è incalcolabile e sono veramente felice di avere avuto l’opportunità di tradurlo, di vedere il testo mentre cambiava di lingua ma non di sostanza. La traduzione di un’opera letteraria è un’impresa impegnativa perché il traduttore, il mediatore che permette la comunicazione tra due lingue e culture diverse, deve veicolare il messaggio del testo originale, rendendolo comprensibile a un nuovo destinatario e, al contempo, cercare di rispettare le scelte stilistiche dell’autore

Contact dermatitis from shoes: an update

Contact dermatitis is a common inflammatory skin condition characterized by erythematous and pruritic skin lesions that occur after contact with a foreign substance. There are two forms of contact dermatitis: irritant and allergic. Irritant contact dermatitis is caused by the non–immune-modulated irritation of the skin by a substance, leading to skin changes. Allergic contact dermatitis is a delayed hypersensitivity reaction in which a foreign substance comes into contact with the skin; skin changes occur after reexposure to the substance. A medical condition referred to as “shoe dermatitis” is a form of contact dermatitis caused by the contact of the foot with parts of the shoe due to these materials. Shoe dermatitis is a diagnostic and therapeutic challenge and is a common type of contact dermatitis. It is imperative the foot and ankle physician become familiar with recognizing signs and symptoms of shoe dermatitis so that their patients can be accurately diagnosis and appropriately treated to avoid secondary infections and disability. This review will first present causative factors for the etiology of shoe contact dermatitis supported by clinical-based evidence as found in the medical literature. Secondly, a description of the signs and symptoms of shoe contact dermatitis will be presented in a narrative fashion. Finally, both treatment options and preventative measures to avoid shoe.

Insulin-Like Growth Factor-I (IGF-1), IGF-Binding Protein-3 (IGFBP-3) and mammographic features

Introduction. The IGF system has recently been shown to play an important role in the regulation of breast tumor cell proliferation. However, also breast density is currently considered as the strongest breast cancer risk factor. It is not yet clear whether these factors are interrelated and if and how they are influenced by menopausal status. The purpose of this study was to examine the possible effects of IGF-1 and IGFBP-3 and IGF-1/IGFBP-3 molar ratio on mammographic density stratified by menopausal status. Patients and methods. A group of 341 Italian women were interviewed to collect the following data: family history of breast cancer, reproductive and menstrual factors, breast biopsies, previous administration of hormonal contraceptive therapy, hormone replacement therapy (HRT) in menopause and lifestyle information. A blood sample was drawn for determination of IGF-1, IGFBP-3 levels. IGF-1/ IGFBP-3 molar ratio was then calculated. On the basis of recent mammograms the women were divided into two groups: dense breast (DB) and non-dense breast (NDB). Student’s t-test was employed to assess the association between breast density and plasma level of IGF-1, IGFBP-3 and molar ratio. To assess if this relationship was similar in subgroups of pre- and postmenopausal women, the study population was stratified by menopausal status and Student’s t-test was performed. Finally, multivariate analysis was employed to evaluate if there were confounding factors that might influence the relationship between growth factors and breast density. Results. The analysis of the relationship between mammographic density and plasma level of IGF-1, IGFBP-3 and IGF-1/ IGFBP-3 molar ratio showed that IGF-1 levels and molar ratio varied in the two groups resulting in higher mean values in the DB group (IGF-1: 109.6 versus 96.6 ng/ml; p= 0.001 and molar ratio 29.4 versus 25.5 ng/ml; p= 0.001) whereas IGFBP-3 showed similar values in both groups (DB and NDB). Analysis of plasma level of IGF-1, IGFBP-3 and IGF-1/IGFBP-3 molar ratio compared to breast density after stratification of the study population by menopausal status (premenopausal and postmenopausal) showed that there was no association between the plasma of growth factors and breast density, neither in premenopausal nor in postmenopausal patients. Multivariate analysis showed that only nulliparity, premenopausal status and body mass index (BMI) are determinants of breast density. Conclusions. Our study provides a strong evidence of a crude association between breast density and plasma levels of IGF-1 and molar ratio. On the basis of our results, it is reasonable to assume that the role of IGF-1 and molar ratio in the pathogenesis of breast cancer might be mediated through mammographic density. IGF-1 and molar ratio might thus increase the risk of cancer by increasing mammographic density.

Tidal Energy ”Round Robin” Tests Comparisons between towing tank and circulating tank results

One key step of the industrial development of a tidal energy device is the testing of scale prototype devices within a controlled laboratory environment. At present, there is no available experimental protocol which addresses in a quantitative manner the differences which can be expected between results obtained from the different types of facilities currently employed for this type of testing. As a consequence, where differences between results are found it has been difficult to confirm the extent to which these differences relate to the device performance or to the test facility type. In the present study, a comparative ”Round Robin” testing programme has been conducted as part of the EC FP VII MaRINET program in order to evaluate the impact of different experimental facilities on the test results. The aim of the trials was to test the same model tidal turbine in four different test facilities to explore the sensitivity of the results to the choice of facility. The facilities comprised two towing tanks, of very different size, and two circulating water channels. Performance assessments in terms of torque, drag and inflow speed showed very similar results in all facilities. However, expected differences between the different tank types (circulating and towing) were observed in the fluctuations of torque and drag measurements. The main facility parameters which can influence the behaviour of the turbine were identified; in particular the effect of blockage was shown to be significant in cases yielding for high thrust coefficients, even at relatively small blockage ratios.

Experiências de (in)justiça com os professores e comportamentos de desvio na adolescência

Tese de Doutoramento em Psicologia na área de especialidade Psicologia Social

Antiplasmodial activity of iron(II) and ruthenium(II) organometallic complexes against Plasmodium falciparum blood parasites

This work reports the in vitro activity against Plasmodium falciparum blood forms (W2 clone, chloroquine-resistant) of tamoxifen-based compounds and their ferrocenyl (ferrocifens) and ruthenocenyl (ruthenocifens) derivatives, as well as their cytotoxicity against HepG2 human hepatoma cells. Surprisingly with these series, results indicate that the biological activity of ruthenocifens is better than that of ferrocifens and other tamoxifen-like compounds. The synthesis of a new metal-based compound is also described. It was shown, for the first time, that ruthenocifens are good antiplasmodial prototypes. Further studies will be conducted aiming at a better understanding of their mechanism of action and at obtaining new compounds with better therapeutic profile.

Tratamiento del rechazo mediado por anticuerpos en pacientes trasplantados renales revisión sistemática

Antecedentes: El trasplante renal es la mejor alternativa terapéutica para la enfermedad renal crónica terminal. Los medicamentos inmunosupresores previenen el rechazo. El rechazo mediado por anticuerpos es frecuente y disminuye la función y duración del injerto. Objetivo: Evaluar sistemáticamente la evidencia disponible relacionada con la eficacia y seguridad del tratamiento para el rechazo mediado por anticuerpos en pacientes trasplantados renales. Metodologia: Revisión sistemática en bases de datos MEDLINE, EMBASE, Scopus y Biblioteca virtual de la salud. Literatura gris google scholar, google academico, www.clinicaltrialsregister.eu, and https://clinicaltrials.gov/. Búsqueda manual referencias artículos pre-seleccionados así como de revisiones previamente publicadas. Se siguieron las recomendacioes guia PRISMA para la identificacion de artículos potenciales, tamizaje y selección teniendo en cuenta los criterios de inclusion. Extracción datos de acuerdo a las variables, revisión calidad de los artículos elegidos utilizando evaluación riesgo de segos de Cochrane. Resultados: Se seleccionaron 9 ensayos clínicos publicados entre 1980 y 2016, incluyeron 222 pacientes (113 brazo de intervención y 109 en el control), seguimiento promedio 16 meses. Intervenciones evaluadas plasmaféresis, inmunoadsorción y rituximab. Hubo una amplia heterogeneidad en la definición de criterios de inclusión, criterios diagnósticos de rechazo y medidas de evaluación de eficacia de las intervenciones. Tres estudios encontraron diferencias estadísticamente significativas entre los grupos de tratamiento. Conclusiones: La evidencia sobre la eficacia de los tratamientos del rechazo mediado por anticuerpos en injertos renales es de baja calidad. Son necesarios ensayos clínicos controlados para poder definir el tratamiento óptimo de estos pacientes.