El componente cultural en los manuales de ELE (niveles A1 y A2) para estudiantes de lengua alemana.

Memoria de máster (Universitat de Barcelona, 2008). Resumen basado en el de la publicación

Propuesta de un manual de tipología textual escrita destinada al ámbito laboral para el desarrollo de la comprensión lectora en los niveles A1, A2 y B1.

Memoria de máster (Universidad Antonio de Nebrija, 2010). Incluye anexos. Resumen basado en el de la publicación

Cómo llevar a cabo un entrenamiento estratégico específico de la interacción oral para los niveles A1 y A2.

Memoria de máster (UIMP-Instituto Cervantes, 2012). Resumen basado en el de la publicación

El dictado como instrumento para promover la interculturalidad en el aula ELE : propuestas para el nivel A1.

Se presenta una actividad dirigida a alumnos con nivel A1 (MCER), diseñada para realizarse en dinámica de parejas, grupos o individual. Los objetivos son: favorecer el desarrollo del alumno como hablante intercultural; posibilitar habilidades y actitudes interculturales en el aula; promover la utilización del dictado como técnica habitual en el aula; favorecer la integración de destrezas; fomentar el aprendizaje cooperativo y la cohesión del grupo; y facilitar el desarrollo de la autonomía de aprendizaje.

La ense??anza de espa??ol como lengua extranjera a estudiantes con deficiencia visual o ceguera : propuesta did??ctica de adaptaci??n de actividades para el DELE A1

Memoria de m??ster (Universidad Francisco de Nebrija, 2013)

Materiales para la clase de espa??ol como lengua extranjera 2013 : nivel A1

Resumen basado en el de la publicaci??n

El laberinto del fauno : explotaci??n did??ctica para el nivel A1

T??tulo del encuentro: ???Expresi??n, interacci??n y mediaci??n orales en el aula de ELE???

Bueno, pues luego hablamos : la presentaci??n de los marcadores pues y bueno en algunos de los manuales ELE para A1

Resumen basado en el de la publicaci??n

Propuesta curricular de la lengua de signos espa??ola : nivel usuario b??sico A1-A2

Coordinaci??n, Unidad de Pol??tica Ling????stica de la Lengua de Signos Espa??ola (Fundaci??n CNSE) ; edici??n, ??rea de Investigaci??n en Lengua de Signos Espa??ola

Ut pictura poesis: artes plásticas y literatura: didácticas paralelas

Actualmente, la enseñanza de la historia del arte como disciplina se imparte en las universidades, en la mayoría de los casos, sin tener en cuenta otras manifestaciones artísticas paralelas en el tiempo y en el espacio. Nuestra propuesta, partiendo de una base teórica que relaciona las artes plásticas y la literatura, subraya las similitudes metodológicas del estudio de las dos disciplinas, sus intercambios de terminología, más común desde la literatura hacia la pintura que al revés, y propone una metodología didáctica que facilite y complemente la comprensión de la historia del arte. El objeto de la presente comunicación es demostrar la utilidad de la enseñanza paralela de la historia de la literatura y de la historia del arte, para mejorar la comprensión de la segunda, y establecer una metodología que permita crear conexiones y paralelismos entre ellas. Hay que aclarar que hablamos de la Historia del Arte por un lado y de la Historia de la Literatura por otro, ya que el término “literatura” es amplio y complejo

Triglyceride-rich lipoproteins inhibit cholesterol efflux to apolipoprotein (apo) A1 from human macrophage foam cells

High circulating levels of triglyceride-rich lipoproteins (TGRL) represent an independent risk factor for coronary artery disease. Here, we show that TGRL inhibit the efflux of cholesterol from 'foam cell' macrophages to lipid-poor apolipoprotein (apo) A1, and may thereby inhibit arterial reverse cholesterol transport and promote the formation of atherosclerotic lesions. Human (THP-1) monocyte-derived macrophages were pre-incubated (48h) with acetylated low-density lipoprotein (AcLDL) to provide a foam cell model of cholesterol efflux to apoA1. Pre-incubation of macrophage 'foam cells' with TGRL (0-200 mug/ml, 0-24 h) inhibited the efflux of exogenously radiolabelled ([H-3]), endogenously synthesised ([C-14]) and cellular cholesterol mass to lipid-poor apoA1, but not control medium, during a (subsequent) efflux period. This inhibition is dependent upon the length of prior exposure to, and concentration of, TGRL employed, but is independent of changes in intracellular triglyceride accumulation or turnover of the cholesteryl ester pool. Despite the negative impact of TGRL on cholesterol efflux, major proteins involved in this process-namely apoE, ABCA1, SR-B1 and caveolin-1-were unaffected by TGRL pre-incubation, suggesting that exposure to these lipoproteins inhibits an alternate, and possibly novel, anti-atherogenic pathway. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

Spectral theory of Toeplitz and Hankel operators on the Bergman space A1

The Fredholm properties of Toeplitz operators on the Bergman space A2 have been well-known for continuous symbols since the 1970s. We investigate the case p=1 with continuous symbols under a mild additional condition, namely that of the logarithmic vanishing mean oscillation in the Bergman metric. Most differences are related to boundedness properties of Toeplitz operators acting on Ap that arise when we no longer have 1

Pungent general anesthetics activate transient receptor potential-A1 to produce hyperalgesia and neurogenic bronchoconstriction

BACKGROUND: Volatile anesthetics such as isoflurane and halothane have been in clinical use for many years and represent the group of drugs most commonly used to maintain general anesthesia. However, despite their widespread use, the molecular mechanisms by which these drugs exert their effects are not completely understood. Recently, a seemingly paradoxical effect of general anesthetics has been identified: the activation of peripheral nociceptors by irritant anesthetics. This mechanism may explain the hyperalgesic actions of inhaled anesthetics and their adverse effects in the airways. METHODS: To test the hypothesis that irritant inhaled anesthetics activate the excitatory ion-channel transient receptor potential (TRP)-A1 and thereby contribute to hyperalgesia and irritant airway effects, we used the measurement of intracellular calcium concentration in isolated cells in culture. For our functional experiments, we used models of isolated guinea pig bronchi to measure bronchoconstriction and withdrawal threshold to mechanical stimulation with von Frey filaments in mice. RESULTS: Irritant inhaled anesthetics activate TRPA1 expressed in human embryonic kidney cells and in nociceptive neurons. Isoflurane induces mechanical hyperalgesia in mice by a TRPA1-dependent mechanism. Isoflurane also induces TRPA1-dependent constriction of isolated bronchi. Nonirritant anesthetics do not activate TRPA1 and fail to produce hyperalgesia and bronchial constriction. CONCLUSIONS: General anesthetics induce a reversible loss of consciousness and render the patient unresponsive to painful stimuli. However, they also produce excitatory effects such as airway irritation and they contribute to postoperative pain. Activation of TRPA1 may contribute to these adverse effects, a hypothesis that remains to be tested in the clinical setting.

Proportions of A1, A2, B and C β-casein protein variants in retail milk in the UK

The A1 variant protein of the β-casein family has been implicated in various disease states although much evidence is weak or contradictory. The primary objective was to measure, for the first time, the proportions of the key β-casein variant proteins in UK retail milk over the course of one year. In total, 55 samples of semi-skimmed milk were purchased from five supermarkets over the course of a year and the proportions of the A1, A2, B and C casein variant proteins were measured, using high resolution HPLC-MS. The results showed that β-casein in UK retail milk comprises approximately 0.58, 0.31, 0.07 and 0.03 A2, A1, B and C protein variants, respectively. The proportion of A2 is higher than some early studies would predict although the reasons for this and any implications for health are unclear