From Unemployment to Sustainable Livelihoods in Ottawa's Technology Sector (Working Paper 44)

Since submission of the draft report to the OECD‐LEED Program on 30 June 2007, a unique seven‐years retrospective study of the unemployed high technology workers was released by Statistics Canada.1 Drawing upon Statistics Canada’s confidential Longitudinal Worker File – itself constructed from four administrative data sources that linked Records of Employment and tax filer information by the Social Insurance Number and firm‐level data by a company identifier – this study was able to identify and trace the re‐employment of those permanently laid off in the high‐tech industry by location. The findings are stunning.

Petri Net Siphon Analysis and Network Centrality Measures for Identifying Combination Therapies in Signaling Pathways

Aberrant behavior of biological signaling pathways has been implicated in diseases such as cancers. Therapies have been developed to target proteins in these networks in the hope of curing the illness or bringing about remission. However, identifying targets for drug inhibition that exhibit good therapeutic index has proven to be challenging since signaling pathways have a large number of components and many interconnections such as feedback, crosstalk, and divergence. Unfortunately, some characteristics of these pathways such as redundancy, feedback, and drug resistance reduce the efficacy of single drug target therapy and necessitate the employment of more than one drug to target multiple nodes in the system. However, choosing multiple targets with high therapeutic index poses more challenges since the combinatorial search space could be huge. To cope with the complexity of these systems, computational tools such as ordinary differential equations have been used to successfully model some of these pathways. Regrettably, for building these models, experimentally-measured initial concentrations of the components and rates of reactions are needed which are difficult to obtain, and in very large networks, they may not be available at the moment. Fortunately, there exist other modeling tools, though not as powerful as ordinary differential equations, which do not need the rates and initial conditions to model signaling pathways. Petri net and graph theory are among these tools. In this thesis, we introduce a methodology based on Petri net siphon analysis and graph network centrality measures for identifying prospective targets for single and multiple drug therapies. In this methodology, first, potential targets are identified in the Petri net model of a signaling pathway using siphon analysis. Then, the graph-theoretic centrality measures are employed to prioritize the candidate targets. Also, an algorithm is developed to check whether the candidate targets are able to disable the intended outputs in the graph model of the system or not. We implement structural and dynamical models of ErbB1-Ras-MAPK pathways and use them to assess and evaluate this methodology. The identified drug-targets, single and multiple, correspond to clinically relevant drugs. Overall, the results suggest that this methodology, using siphons and centrality measures, shows promise in identifying and ranking drugs. Since this methodology only uses the structural information of the signaling pathways and does not need initial conditions and dynamical rates, it can be utilized in larger networks.

Late-career international migration and reproductive work. A comparison between Peruvian and Ukrainian women in the Southern Europe

Research on the relationship between reproductive work and women´s life trajectories including the experience of labour migration has mainly focused on the case of relatively young mothers who leave behind, or later re-join, their children. While it is true that most women migrate at a younger age, there are a significant number of cases of men and women who move abroad for labour purposes at a more advanced stage, undertaking a late-career migration. This is still an under-estimated and under-researched sub-field that uncovers a varied range of issues, including the global organization of reproductive work and the employment of migrant women as domestic workers late in their lives. By pooling the findings of two qualitative studies, this article focuses on Peruvian and Ukrainian women who seek employment in Spain and Italy when they are well into their forties, or older. A commonality the two groups of women share is that, independently of their level of education and professional experience, more often than not they end up as domestic and care workers. The article initially discusses the reasons for late-career female migration, taking into consideration the structural and personal determinants that have affected Peruvian and Ukrainian women’s careers in their countries of origin and settlement. After this, the focus is set on the characteristics of domestic employment at later life, on the impact on their current lives, including the transnational family organization, and on future labour and retirement prospects. Apart from an evaluation of objective working and living conditions, we discuss women’s personal impressions of being domestic workers in the context of their occupational experiences and family commitments. In this regard, women report varying levels of personal and professional satisfaction, as well as different patterns of continuity-discontinuity in their work and family lives, and of optimism towards the future. Divergences could be, to some extent, explained by the effect of migrants´ transnational social practices and policies of states.

La narcotización del activismo guerrillero de las FARC y el ELN, 1998-2012

El artículo que se presenta tiene como propósito plantear hasta qué punto, durante los últimos años, con motivo de las políticas de seguridad, especialmente, de Andrés Pastrana (1998- 2002) y Álvaro Uribe (2002-2010), las guerrillas de las FARC y del ELN han experimentado un importante proceso de transformación. Lo anterior, por el cambio en las dinámicas espaciales del conflicto armado, que ha tendido a concentrarse en enclaves periféricos, de índole fronteriza, pero, sobre todo, caracterizados por una mayor dependencia de las finanzas provenientes del cultivo ilícito. Esto termina por desnaturalizar a las guerrillas y favorecer la posibilidad de entender las nuevas dinámicas de la violencia en Colombia así como las opciones reales de superación del conflicto.

Is Trading Behavior Stable Across Contexts? Evidence from Style and Multi-Style Investors

In this paper we study priming of identity within the context of inherent vs. contextual financial decision making. We use a sample of individual trading accounts in equity-style funds taken from one fund family to test the hypothesis that trading styles are inherent vs. contextual. Our sample contains investors who invest either in a growth fund, a value fund, or both. We document behavioral differences between growth fund investors and value fund investors. We find that their trades depend on past returns in different ways: growth fund investors tend towards momentum trading and value fund investors tend towards contrarian trading. These differences may be due to inherent clientele characteristics, including beliefs about market prices, specific personality traits and cognitive strategies that cause them to self-select into one or the other style. We use a sample of investors that trade in both types of funds to test this proposition. Consistent with the contextual hypothesis, we find that investors who hold both types of funds trade growth fund shares differently than value fund shares.

Planejamento municipal do turismo: diretrizes e perspectivas - o caso da SETURDE

Given the uncertainties of the environment in today's world, strategic planning is again discussed as an important tool to position the organization in future likely. To address this a more dynamic and less linear, trying to adapt the multiple realities, the method of scenarios can be one of the strategies to anticipate future designs. In the public sphere, an efficient implementation of human resources and financial managers require a new approach to the formulation of strategies. Tourism, in turn, presents itself as an important segment of the national economy shaped up as a major source of funds for the formation of the Gross Domestic Product - GDP - of states and municipalities. This study aims to know the guidelines and perspectives of municipal planning of tourism in the city of Natal/RN from the case by the representatives of the sector. The survey was developed based on a qualitative, exploratory, based on the case in the Secretaria Municipal de Turismo e Desenvolvimento Econômico - SETURDE. The results express that the body goes through a time of changes in its organizational structure and in defining its role with the local tourism. The national plan for tourism and the choice of Christmas as the host city for the World Cup in 2014 have stimulated interest in developing a formal strategic planning in the organization. However, when it comes to more complex tools, such as the method of future scenarios, the technical know its definition and importance for future actions. The results presented support the conclusion that the actions are designed intuitively and without complying with the scientific methods developed for this purpose, as the method of strategic scenarios. However, the evidence beginning to emerge from the plans and documents issued by the federal government, as well as the Secretary's own initiative, direct the actions of the body to coordinate and act as a fulcrum for local action to the increase in tourism

Supporting Cubane’s Renaissance: Metathesis reactions on 4-iodo-1-vinylcubane and Stetter reaction on 1-iodocubane-4-carboxaldehyde

Cubane is a peculiar cube-shaped alkane molecule with a rigid, regular structure. This makes it a good scaffold, i.e. a molecular platform to which the substituents are arranged in a specific and fixed orientation. Moreover, cubane has a body diagonal of 2.72 Å, very similar to the distance across the benzene ring, i.e. 2.79 Å. Thus, it would be possible to use cubane as a scaffold in medicinal and material chemistry as a benzene isostere 1,2. This could lead to advantages in terms of solubility and toxicity and could provide novel properties. For this purpose, the possibility of performing “modern organic chemistry” on the cubane scaffold has to be studied. This project was entirely carried out in the framework of the Erasmus+ mobility programme at the Trinity College (Dublin, IRL) under the supervision of prof. M. O. Senge. The main goal of this project was to widen the knowledge on cubane chemistry. In particular, it was decided to test reactions that were never applied to the scaffold before, such as metathesis of 4-iodo-1-vinylcubane and Stetter reaction of 1-iodocubane-4-carboxaldehyde. These two molecules were synthesized in 10 and 9 steps respectively from commercially available cyclopentanone, following a known procedure. Unfortunately, metathesis with different olefins, such as styrene, α,β unsaturated compounds and linear α-olefins failed under different conditions, highlighting cubane behaves as a Type IV, challenging olefin under metathesis conditions. Even the employment of a specific catalyst for hindered olefins failed in the cross-coupling with linear α-olefins. On the other hand, two new molecules were synthesized via Stetter reaction and benzoin condensation respectively. Even if the majority of the reactions were not successful, this work can be seen as an inspiration for further investigation on cubane chemistry, as new questions were raised and new opportunities were envisioned.

Colmeias: uma estratégia didático-pedagógica para potencializar a aprendizagem significativa através da colaboração nas redes sociais em contextos móveis

O presente trabalho procura atender as necessidades dos processos educativos da atualidade, reconhecendo que esses ocorrem numa sociedade denominada como a Sociedade da Informação (SI), num ambiente em que os aprendizes são nativos digitais. Na SI presencia-se um momento marcado por um modelo computacional móvel, no qual também é possível constatar-se a emergência de um novo paradigma educacional - a aprendizagem com mobilidade - que possibilita a integração das tecnologias móveis com os processos de ensino e de aprendizagem. Além disso, observa-se a ascensão do emprego das redes sociais na Internet (RSI) no dia a dia dos indivíduos impactando as práticas estabelecidas na SI. Nesse cenário, visando integrar a aprendizagem móvel com os recursos das RSI para promover-se uma educação mais sintonizada com o perfil atual dos estudantes, expõe-se nessa tese uma nova proposta metodológica - a Colmeias almejando dessa maneira facilitar uma aprendizagem significativa a partir de um processo colaborativo, em rede e em contextos de mobilidade. Com embasamento teórico em diversos autores, entre os quais se destacam Vygostky, Bruner e Ausubel, apoiados por Júlio Cesar Santos e Pierry Dillenbourg, salienta-se que a estratégia Colmeias representa um caminho alternativo para aqueles professores que desejam promover uma educação mais coerente com a atualidade. Nessa pesquisa ainda se apresenta a sua aplicação por meio de um estudo de caso na Matemática procurando, assim, aproximar a teoria com a prática.

Fachada flexível para casa padronizada em condomínios

The employment of flexibility in the design of façades makes them adaptable to adverse weather conditions, resulting in both minimization of environmental discomfort and improvement of energy efficiency. The present study highlights the potential of flexible façades as a resource to reduce rigidity and form repetition, which are usually employed in condominiums of standardized houses; as such, the work presented herein contributes to field of study of architectural projects strategies for adapting and integrating buildings within the local climate context. Two façade options were designed using as reference the bionics and the kinetics, as well as their applications to architectural constructions. This resulted in two lightweight and dynamic structures, which cater to constraints of comfort through combinations of movements, which control the impact of solar radiation and of cooling in the environment. The efficacy and technical functionality of the façades were tested with comfort analysis and graphic computation software, as well as with physical models. Thus, the current research contributes to the improvement of architectural solutions aimed at using passive energy strategies in order to offer both better quality for the users and for the sustainability of the planet

Processo de Abertura de Conta Bancária - Início da Relação entre Clientes e Instituições Bancárias

Mestrado em Contabilidade e Gestão de Instituições Financeiras

QUALIDADE DE VIDA DE PROFESSORAS DO ENSINO BÁSICO DA REDE PÚBLICA

Objetivo: Avaliar os aspectos associados à qualidade de vida (QV) de professoras do ensino básico da rede pública de Viçosa-MG, buscando relações com a classe econômica. Métodos: Trata-se de um estudo descritivo transversal, desenvolvido entre março e outubro de 2013, realizado com 156 professoras da cidade de Viçosa-MG. Foram aplicados os questionários World Health Organization Quality of Life/BREF e o Critério de Classificação Econômica. Utilizou-se também um questionário contendo tempo de atuação e carga horária semanal de trabalho. Para comparação dos domínios da QV entre as classes econômicas, utilizou-se o teste ANOVA one way, com post hoc de Tukey. Para todos os tratamentos, adotou-se um nível de significância de p<0,05. Resultados: As avaliadas apresentaram idade média de 43,88 (+ 10,61) anos, carga horária de trabalho semanal de 29,00 (+ 10,35) horas e tempo de atuação profissional de 16,17 (+ 8,91) anos. A maioria das avaliadas se encontrava na classe econômica B1/B2, com 60,3%. O escore médio da QV geral foi de 68,43 (+ 11,69) pontos, com maiores valores para os domínios “relações sociais” e “físico”. Foi encontrada uma redução na média do domínio “meio ambiente” em relação à menor classe econômica (p=0,011). Houve correlação fraca e inversa entre o domínio “relações sociais” e a carga horária semanal de trabalho (r=-0,16; p=0,031). Conclusão: A QV da população estudada foi considerada entre regular e boa, levando-se em conta a escala do protocolo. Houve associação somente entre o domínio “meio ambiente” e a classe econômica.

Utilização do mapa espacial de radiação e dose acumulada como ferramenta para otimização de doses em pacientes e trabalhadores nas clínicas de medicina nuclear

This study has as general aim to propose a spatial map of doses as an auxiliary tool in assessing the need for optimization of the workplace in nuclear medicine services. As specific aims, we assessed the workers individual dosimetry; we analyzed the facilities of the nuclear medicine services; and we evaluated environment exposure rates. The research is characterized as a case study, with an exploratory and explanatory nature. It was conducted in three Nuclear Medicine Services, all established in the Northwest of the Paraná State. Results indicated that the evaluated dose rates and workers dosimetry, in all the dependencies of the surveyed services, are within the limits of annual doses. However some exceeded the limits recommended in the standard CNEN-NN 3:01 (2014). It was concluded that the spatial map dose is an important tool for nuclear medicine services because it facilitates the visualization of areas with highest concentration of radiation, and also helps in the constant review of these measures and resources, aiding in the identification of any failures and shortcomings, providing resources to correct any issues and prevent their repetition. The spatial map dose is also important for the regular inspection, evaluating if the radiation protection objectives are being met.

Emprego para jovens cientistas no sector empresarial : Expectativas e realidade

A formação avançada de recursos humanos tem vindo a ser objecto de um elevado investimento, com base no pressuposto de que estes recursos desempenham um papel crucial no desenvolvimento tecnológico. No entanto, os jovens pós-graduados têm vindo a deparar-se com dificuldades crescentes no mercado de trabalho académico, dificuldades essas que não estão a ser compensadas com o aparecimento de novas oportunidades no mercado de trabalho empresarial. Tal sugere a existência de alguma desadequação entre a oferta e a procura, ou seja, entre as competências dos indivíduos e as pretendidas por um mercado de trabalho em mutação. Este artigo aborda esse problema, examinando a questão do emprego de jovens cientistas no sector empresarial em Portugal. A investigação foi conduzida tendo em consideração quer o ponto de vista das empresas, quer o dos jovens cientistas e centrou-se nas seguintes questões: a) no caso das empresas que empregam mestres e doutorados, que tipo de competências são procuradas, como são geridos este tipo de recursos e que tipo de obstáculos se deparam à sua integração e utilização plena; b) no caso das empresas que não empregam, mas que poderiam beneficiar destes recursos, quais os motivos para a sua relutância; c) no caso dos jovens cientistas, qual a sua atitude em relação a uma carreira no sector empresarial e em que condições estariam dispostos a segui-la. A investigação permitiu detectar alguns desajustamentos entre os objectivos e expectativas das empresas e dos cientistas, bem como identificar alguns factores de relutância em ambos os grupos. Estes resultados permitiram- nos avançar algumas sugestões no sentido de promover o emprego de jovens cientistas no sector empresarial.

Przestrzenne formy upamiętniania Zagłady

This book is a synthesizing reflection on the Holocaust commemoration, in which space becomes a starting point for discussion. The author understands space primarily as an amalgam of physical and social components, where various commemorative processes may occur. The first part of the book draws attention to the material aspect of space, which determines its character and function. Material culture has been a long ignored and depreciated dimension of human culture in the humanities and social sciences, because it was perceived as passive and fully controlled by human will, and therefore insignificant in the course of social and historical processes. An example of the Nazi system perfectly illustrates how important were the restrictions and prohibitions on the usage of mundane objects, and in general, the whole material culture in relation to macro and micro space management — the state, cities, neighborhoods and houses, but also parks and swimming pools, factories and offices or shops and theaters. The importance of things and space was also clearly visible in exploitative policies present in overcrowded ghettos and concentration and death camps. For this very reason, when we study spatial forms of Holocaust commemoration, it should be acknowledged that the first traces, proofs and mementoes of the murdered were their things. The first "monuments" showing the enormity of the destruction are thus primarily gigantic piles of objects — shoes, glasses, toys, clothes, suitcases, toothbrushes, etc., which together with the extensive camps’ space try to recall the scale of a crime impossible to understand or imagine. The first chapter shows the importance of introducing the material dimension in thinking about space and commemoration, and it ends with a question about one of the key concepts for the book, a monument, which can be understood as both object (singular or plural) and architecture (sculptures, buildings, highways). However, the term monument tends to be used rather in a later and traditional sense, as an architectural, figurative form commemorating the heroic deeds, carved in stone or cast in bronze. Therefore, the next chapter reconstructs this narrower line of thinking, together with a discussion about what form a monument commemorating a subject as delicate and sensitive as the Holocaust should take on. This leads to an idea of the counter-monument, the concept which was supposed to be the answer to the mentioned representational dilemma on the one hand, and which would disassociate it from the Nazi’s traditional monuments on the other hand. This chapter clarifies the counter-monument definition and explains the misunderstandings and confusions generated on the basis of this concept by following the dynamics of the new commemorative form and by investigating monuments from the ‘80s and ‘90s erected in Germany. In the next chapter, I examine various forms of the Holocaust commemoration in Berlin, a city famous for its bold, monumental, and even controversial projects. We find among them the entire spectrum of memorials – big, monumental, and abstract forms, like Peter Eisenman’s Memorial to the Murdered Jews of Europe or Daniel Liebeskind’s Jewish Museum Berlin; flat, invisible, and employing the idea of emptiness, like Christian Boltanski’s Missing House or Micha Ullman’s Book Burning Memorial; the dispersed and decentralized, like Renata Stih and Frieder Schnock’s Memory Places or Gunter Demnig’s Stumbling Blocks. I enrich descriptions of the monuments by signaling at this point their second, extended life, which manifests itself in the alternative modes of (mis)use, consisting of various social activities or artistic performances. The formal wealth of the outlined projects creates a wide panorama of possible solutions to the Holocaust commemoration problems. However, the discussions accompanying the building of monuments and their "future life" after realization emphasize the importance of the social component that permeates the biography of the monument, and therefore significantly influences its foreseen design. The book also addresses the relationship of space, place and memory in a specific situation, when commemoration is performed secretly or remains as unrealized potential. Although place is the most common space associated with memory, today the nature of this relationship changes, and is what indicates popularity and employment of such terms as Marc Augé’s non-places or Pierre Nora’s site of memory. I include and develop these concepts about space and memory in my reflections to describe qualitatively different phenomena occurring in Central and Eastern European countries. These are unsettling places in rural areas like glades or parking lots, markets and playgrounds in urban settings. I link them to the post-war time and modernization processes and call them sites of non-memory and non-sites of memory. Another part of the book deals with a completely different form of commemoration called Mystery of memory. Grodzka Gate - NN Theatre in Lublin initiated it in 2000 and as a form it situates itself closer to the art of theater than architecture. Real spaces and places of everyday interactions become a stage for these performances, such as the “Jewish town” in Lublin or the Majdanek concentration camp. The minimalist scenography modifies space and reveals its previously unseen dimensions, while the actors — residents and people especially related to places like survivors and Righteous Among the Nations — are involved in the course of the show thanks to various rituals and symbolic gestures. The performance should be distinguished from social actions, because it incorporates tools known from religious rituals and art, which together saturate the mystery of memory with an aura of uniqueness. The last discussed commemoration mode takes the form of exposition space. I examine an exhibition concerning the fate of the incarcerated children presented in one of the barracks of the Majdanek State Museum in Lublin. The Primer – Children in Majdanek Camp is unique for several reasons. First, because even though it is exhibited in the camp barrack, it uses a completely different filter to tell the story of the camp in comparison to the exhibitions in the rest of the barracks. For this reason, one experiences immersing oneself in all subsequent levels of space and narrative accompanying them – at first, in a general narrative about the camp, and later in a specifically arranged space marked by children’s experiences, their language and thinking, and hence formed in a way more accessible for younger visitors. Second, the exhibition resigns from didacticism and distancing descriptions, and takes an advantage of eyewitnesses and survivors’ testimonies instead. Third, the exhibition space evokes an aura of strangeness similar to a fairy tale or a dream. It is accomplished thanks to the arrangement of various, usually highly symbolic material objects, and by favoring the fragrance and phonic sensations, movement, while belittling visual stimulations. The exhibition creates an impression of a place open to thinking and experiencing, and functions as an asylum, a radically different form to its camp surrounding characterized by a more overwhelming and austere space.