976 resultados para semilinear partial differential equation


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We prove the approximate controllability of the semilinear heat equation in RN, when the nonlinear term is globally Lipschitz and depends both on the state u and its spatial gradient Ñu. The approximate controllability is viewed as the limit of a sequence of optimal control problems. In order to avoid the difficulties related to the lack of compactness of the Sobolev embeddings, we work with the similarity variables and use weighted Sobolev spaces.

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By using the theory of semigroups of growth α, we discuss the existence of mild solutions for a class of abstract neutral functional differential equations. A concrete application to partial neutral functional differential equations is considered.

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Die vorliegende Arbeit befaßt sich mit einer Klasse von nichtlinearen Eigenwertproblemen mit Variationsstrukturin einem reellen Hilbertraum. Die betrachteteEigenwertgleichung ergibt sich demnach als Euler-Lagrange-Gleichung eines stetig differenzierbarenFunktionals, zusätzlich sei der nichtlineare Anteil desProblems als ungerade und definit vorausgesetzt.Die wichtigsten Ergebnisse in diesem abstrakten Rahmen sindKriterien für die Existenz spektral charakterisierterLösungen, d.h. von Lösungen, deren Eigenwert gerade miteinem vorgegeben variationellen Eigenwert eines zugehörigen linearen Problems übereinstimmt. Die Herleitung dieserKriterien basiert auf einer Untersuchung kontinuierlicher Familien selbstadjungierterEigenwertprobleme und erfordert Verallgemeinerungenspektraltheoretischer Konzepte.Neben reinen Existenzsätzen werden auch Beziehungen zwischenspektralen Charakterisierungen und denLjusternik-Schnirelman-Niveaus des Funktionals erörtert.Wir betrachten Anwendungen auf semilineareDifferentialgleichungen (sowieIntegro-Differentialgleichungen) zweiter Ordnung. Diesliefert neue Informationen über die zugehörigenLösungsmengen im Hinblick auf Knoteneigenschaften. Diehergeleiteten Methoden eignen sich besonders für eindimensionale und radialsymmetrische Probleme, während einTeil der Resultate auch ohne Symmetrieforderungen gültigist.

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In this paper, we prove that infinite-dimensional vector spaces of α-dense curves are generated by means of the functional equations f(x)+f(2x)+⋯+f(nx)=0, with n≥2, which are related to the partial sums of the Riemann zeta function. These curves α-densify a large class of compact sets of the plane for arbitrary small α, extending the known result that this holds for the cases n=2,3. Finally, we prove the existence of a family of solutions of such functional equation which has the property of quadrature in the compact that densifies, that is, the product of the length of the curve by the nth power of the density approaches the Jordan content of the compact set which the curve densifies.

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Thesis (Ph.D.)--University of California, Berkeley, 1922.

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We consider the semilinear Schrodinger equation -Delta(A)u + V(x)u = Q(x)vertical bar u vertical bar(2* -2) u. Assuming that V changes sign, we establish the existence of a solution u not equal 0 in the Sobolev space H-A,V(1) + (R-N). The solution is obtained by a min-max type argument based on a topological linking. We also establish certain regularity properties of solutions for a rather general class of equations involving the operator -Delta(A).

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We consider the solvability of the Neumann problem for the equation -Delta u + lambda u = 0, partial derivative u/partial derivative v = Q(x)vertical bar u vertical bar(q-2)u on partial derivative Omega, where Q is a positive and continuous coefficient on partial derivative Omega, lambda is a parameter and q = 2(N - 1)/(N - 2) is a critical Sobolev exponent for the trace embedding of H-1(Omega) into L-q(partial derivative Omega). We investigate the joint effect of the mean curvature of partial derivative Omega and the shape of the graph of Q on the existence of solutions. As a by product we establish a sharp Sobolev inequality for the trace embedding. In Section 6 we establish the existence of solutions when a parameter lambda interferes with the spectrum of -Delta with the Neumann boundary conditions. We apply a min-max principle based on the topological linking.

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The author is partially supported by: M. U. R. S. T. Prog. Nazionale “Problemi e Metodi nella Teoria delle Equazioni Iperboliche”.

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∗The author was partially supported by M.U.R.S.T. Progr. Nazionale “Problemi Non Lineari...”

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Mathematics Subject Classification: 26A33, 45K05, 35A05, 35S10, 35S15, 33E12

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2000 Mathematics Subject Classification: 26A33, 33C60, 44A15, 35K55

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In this paper we discuss the existence of mild, strict and classical solutions for a class of abstract integro-differential equations in Banach spaces. Some applications to ordinary and partial integro-differential equations are considered.

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We study the existence of weighted S-asymptotically omega-periodic mild solutions for a class of abstract fractional differential equations of the form u' = partial derivative (alpha vertical bar 1)Au + f(t, u), 1 < alpha < 2, where A is a linear sectorial operator of negative type.

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In this paper we discuss the existence of solutions for a class of abstract partial neutral functional differential equations.

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Background: MicroRNAs (miRNAs) are short non-coding RNAs that inhibit translation of target genes by binding to their mRNAs. The expression of numerous brain-specific miRNAs with a high degree of temporal and spatial specificity suggests that miRNAs play an important role in gene regulation in health and disease. Here we investigate the time course gene expression profile of miR-1, -16, and -206 in mouse dorsal root ganglion (DRG), and spinal cord dorsal horn under inflammatory and neuropathic pain conditions as well as following acute noxious stimulation. Results: Quantitative real-time polymerase chain reaction analyses showed that the mature form of miR-1, -16 and -206, is expressed in DRG and the dorsal horn of the spinal cord. Moreover, CFA-induced inflammation significantly reduced miRs-1 and -16 expression in DRG whereas miR-206 was downregulated in a time dependent manner. Conversely, in the spinal dorsal horn all three miRNAs monitored were upregulated. After sciatic nerve partial ligation, miR-1 and -206 were downregulated in DRG with no change in the spinal dorsal horn. On the other hand, axotomy increases the relative expression of miR-1, -16, and 206 in a time-dependent fashion while in the dorsal horn there was a significant downregulation of miR-1. Acute noxious stimulation with capsaicin also increased the expression of miR-1 and -16 in DRG cells but, on the other hand, in the spinal dorsal horn only a high dose of capsaicin was able to downregulate miR-206 expression. Conclusions: Our results indicate that miRNAs may participate in the regulatory mechanisms of genes associated with the pathophysiology of chronic pain as well as the nociceptive processing following acute noxious stimulation. We found substantial evidence that miRNAs are differentially regulated in DRG and the dorsal horn of the spinal cord under different pain states. Therefore, miRNA expression in the nociceptive system shows not only temporal and spatial specificity but is also stimulus-dependent.