972 resultados para Hepatite C Aspectos genéticos - Teses
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Foram utilizados 24 sunos desmamados, distribudos em quatro tratamentos, com seis animais em cada. Os sunos dos tratamentos 1, 2, 3 e 4 receberam, durante 90 dias, rao com respectivamente: 0,0, 0,2, 0,4 e 0,6% de sementes de Crotalaria spectabilis. Os animais que morreram durante o perodo experimental foram necropsiados logo aps a morte. Os sobreviventes foram sacrificados no ltimo dia do experimento. Durante as necropsias, foram colhidos fragmentos do fgado, rim, pulmo e estmago, para realizao de exame histopatolgico. Os principais sintomas da intoxicao foram edemas subcutneos, principalmente nos membros, na face e regio do pescoo, mucosas oral e ocular plidas, cerdas eriadas, caquexia e apatia. O hidropericrdio foi a leso macroscpica mais comum, acometendo vrios animais que receberam a rao contaminada. As principais leses microscpicas foram fibrose, proliferao de ductos biliares e megalocitose no fgado, broncopneumonia e bronquite crnicas, megalocitose de clulas epiteliais tubulares renais, nefrose e nefrite crnica, bem como gastrite e ulcerao gstrica. Os resultados destes experimentos indicam que rao contaminada com sementes de C. spectabilis, nas propores utilizadas, foi txica para sunos.
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No presente estudo, sinais clnicos e alteraes patolgicas foram avaliados por 30 dias em frangos de corte, linhagem Cobb, machos, com dez dias de idade, infectados com Eimeria acervulina. Foram utilizados 192 animais distribudos em 3 grupos: grupo A inoculado com 1x10(6) oocistos esporulados; grupo B inoculado com 1x10(5) oocistos esporulados; grupo C inoculado com gua destilada. Os sinais clnicos observados foram anorexia, diarria e apatia. As alteraes patolgicas macroscpicas observadas foram: enterite, hiperemia seguido de congesto intestinal, excesso de exsudato mucoso no lmen do intestino delgado, palidez e desidratao muscular, alto acmulo de bile na vescula biliar e deposio de gordura heptica. A atrofia de vilosidades e alta presena de clulas inflamatrias foram as alteraes microscpicas observadas no epitlio intestinal. Na anlise histopatolgica do fgado observaram-se infiltrados inflamatrios e deposio de gordura. Os resultados demonstraram que frangos de corte infectados experimentalmente com E. acervulina apresentam progressivas leses intestinais de intensidade varivel e que essas anormalidades so as principais causas de reduo no desenvolvimento da ave.
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The effect of environmental and genetic effects on the farrowing interval in Dalland (C-40) sows in the Southeast of Brazil was studied. Data consisting of 1,013 farrowing intervals recorded in two herds were analyzed, using a model that included the sire and the dam as random effects and the year of farrowing, the herd and the farrowing season as fixed effects, plus the covariables sow's age at farrowing, litter size at birth, lactation length and weaning-estrus interval. For the farrowing interval first only, variance components were estimated by REML, with an animal model that included, as fixed effect, a contemporary group and, as random effects, the additive genetic variance and the error. The mean farrowing interval was 140.9+5.7 days, with a 4.0% coefficient of variation. Variance analysis showed no effect of either year, season of farrowing or herd on the farrowing interval. The sire effect was not important for the farrowing interval, but the dam represented an important source of variation. The total number of piglets born and the sow's age at farrowing had no influence on the farrowing interval. The length of lactation exerted an influence on the farrowing interval, accounting for 19.4% of the total variation of this trait. Likewise, the linear regression of the weaning-estrus interval in relation to the farrowing interval was highly significant, accounting for 51.7% of the total variation. The heritability estimate was 0.00, suggesting that no genetic gain can be obtained by selection for a shorter farrowing interval.
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The genetic and environmental factors that affect age at first conception (AFC) of gilts were evaluated, using 466 observations of Dalland animals (C-40). The software program MTDFREML was used to assess the genetic parameters on an animal model that included as fixed effect, contemporary group and, as random effects, the additive genetic, the common litter and the error. Mean value of AFC was 241.1225.9 days, with CV of 8.5 %. Variance analysis showed that year (P<0.01), season (P<0.01) and herd effects (P<0.01) were important sources of variation of AFC. The throat effect (P=0.34) was not important for the AFC, but the mother of the gilts (P<0.01) was an important source of variation. The heritability estimate was 0.440.14 that this trait would yield genetic gain as a response to the selection.
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Foram estimadas as correlaes genticas entre caractersticas de produo de leite (produo de leite, gordura, protena e durao da lactao em at 305 dias, na primeira lactao), caractersticas de peso (taxa de crescimento de novilhas entre 12-24 meses e peso mdio de vacas) e idade ao primeiro parto, em uma populao de fmeas Mestio Leiteiro Brasileiro (MLB), por meio de metodologia REML, sob modelo animal. As estimativas de herdabilidade das caractersticas estudadas na ordem acima foram, respectivamente, 0,28 0,08, 0,300,11, 0,280,09, 0,190,07, 0,180,06, 0,420,10 e 0,480,12. As correlaes genticas entre peso mdio da vaca e a produo de leite, gordura e protena foram, respectivamente, -0,220,22, -0,490,31 e -0,220,23 e da taxa de crescimento das novilhas com a produo de leite, gordura e protena foram respectivamente, -0,590,35, -0,730,44 e -0,620,37. As correlaes genticas entre produo de leite, peso mdio das vacas e taxa de crescimento das novilhas com idade ao primeiro parto foram respectivamente, 0,050,18, -0,050,18 e 0,020,20. A alta correlao gentica (0,930,02) entre produo de leite e durao da lactao indicou que no se deve remover a variao na durao da lactao na seleo de gado leiteiro tropical.
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Foram utilizados 128.700, 44.227, 90.383, 47.506, 42.619, 45.057, 17.666 e 27.181 dados, respectivamente, de peso desmama (PD), peso ao sobreano (PS), escore de umbigo desmama (UD), escore de umbigo desmama de macho (UDM), escore de umbigo desmama de fmea (UDF), escore de umbigo ao sobreano (US), escore de umbigo ao sobreano de macho (USM) e escore de umbigo ao sobreano de fmea (USF) com o objetivo de estimar parmetros genéticos de escore visual do umbigo e as respectivas correlaes genticas com as caractersticas de crescimento - peso desmama e peso ao sobreano -, em bovinos da raa Nelore, aplicando-se um modelo animal em anlises uni e bicaractersticas. As estimativas de herdabilidade (h) para as caractersticas UD, UDM, UDF, US, USM, USF, PD e PS foram de 0,140,01; 0,180,02; 0,150,01; 0,260,01; 0,320,03; 0,270,02, 0,290,01 e 0,270,02, respectivamente, em anlises unicaractersticas. em anlises bicaractersticas, as estimativas de h para UD, US, PD e PS foram de 0,15, 0,27, 0,29 e 0,45, respectivamente. As correlaes genticas estimadas entre UDM e UDF, entre USM e USF e entre UD e US foram positivas e altas, as correlaes genticas entre escore do umbigo e caractersticas de crescimento foram todas positivas e de magnitudes de baixa a moderada.
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The present research was accomplished under field and laboratory conditions (T= 25[plus or minus]2[degree] C, R.H.= 70[plus or minus] 10 % and fotoperiod= 12 horas) at FCA/UNICASTELO from Fernandopolis-SP, Brazil. The feeding preference of corn bug Leptoglossus zonatus Dallas, 1852 (Hemiptera: Coreidae) was evaluated on corn genotypes AL-Bianco, AL-Manduri, AL-25 Piratininga, AL-34 e AL-Manduri in the field. Besides, some behavioral factors relative to infestation and oviposition were observed. In laboratory, the nymph's development was evaluated on ears from each corn genotype, aiming to verify the non-preference and/or antibiosis ocurrence. The females of L. zonatus preferred to oviposite on sheats from leaves. Adults and nymphs may occur in whole parts of the plants. The AL-25, AL-34, AL-Manduri and AL-Bandeirante corn genotypes were classified as moderately resistant, expressing non-preference and/or antibiosis against the corn bug. In other way AL-Bianco was the most suscetible to nymphs of the insect.
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Objetivou-se com este trabalho avaliar a variabilidade dos depsitos de traadores, simulando herbicidas aplicados em ps-emergncia, em populaes de Brachiaria plantaginea e Commelina benghalensis infestantes da cultura da soja. Os depsitos dos traadores foram tambm avaliados em plantas da cultura, utilizando-se o pulverizador de barra tratorizado, com pontas de jato plano da srie 110-SF-03, aplicando o volume de 250 L ha-1 de calda preparada com 0,18% de corante Azul Brilhante e 0,18% de Amarelo Saturn Yellow. Os alvos naturais utilizados foram: plantas de soja com 150 repeties; B. plantaginea no estdio de duas a oito folhas, coletadas na linha da cultura com 141 repeties; e B. plantaginea e C. benghalensis nas entrelinhas, com 150 e 50 repeties, respectivamente. Os alvos artificiais foram constitudos por lminas distribudas a 0, 12,2 e 22,5 cm da linha da cultura. Aps a aplicao, os alvos foram coletados individualmente e lavados com 30, 20 e 15 mL de gua deionizada, para soja, lminas e plantas daninhas, respectivamente. Estas originaram as amostras analisadas em espectrofotmetro, estimando-se o depsito de calda em L por planta e L cm de rea foliar. Foram ajustadas curvas de regresso entre os depsitos unitrios e as freqncias acumuladas, utilizando-se o modelo de Gompertz. As relaes entre os depsitos mximos e mnimos foram de 7, 4, 10 e 6 para soja, C. benghalensis e B. plantaginea na linha e na entrelinha, respectivamente. As plantas de B. plantaginea da entrelinha receberam, em mdia, 34% a mais de depsito do que as plantas da linha.
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The objective of this study was to evaluate the amount of spray deposition on peanut plants (Aracahis hypogaea) and on the weed Brachiaria plantaginea, in the rows and inter rows of the culture, as well as the amount of deposition on the soil. The study was conducted in the field using the peanut cultivar IAC Tatu-ST and the treatment applications were performed at the vegetative (V1) and reproductive (R2) stages. Brilliant Blue (FD&C-1) was used as tracer in water solution, at 500 ppm. The treatments were constituted of seven spray nozzles: XR 110015 VS (150 L ha(-1)), XR 11002 VS (200 L ha(-1)), TX-VK 6 (150 L ha(-1)), TX-VK 8 (200 L ha(-1)), AI 110015 VS (150 L ha(-1)), AI11002 VS (200 L ha(-1)) and TJ60 11002 VS (150 and 200 L ha(-1)). A randomized block design was used, with four replications. The results showed that the application of a larger spray volume increased the amount of depositions on the plants IAC Tatu ST at both stages of crop development, with the exception of spray nozzles XR 110015 VS and AI11002 VS, at the vegetative (V1) and reproductive (R2) stages of the culture, respectively; the greatest loss of drops in applications on the soil at the vegetative stage (V1) was provided by the spray nozzles AI 110015 VS and AI 11002 VS; however, at the reproductive stage (R2), the spray nozzle XR 11002 VS caused the greatest loss; The spray nozzles XR 11002 VS, AI 110015 VS, and TJ60 11002 VS (150 L ha(-1)) provided higher depositions on the leaves of B. plantaginea planted in the row than between the rows in the applications at the vegetative stage (V1), while at the reproductive stage (R2), the spray nozzles showed similar results for the deposition of droplets on the weed.
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Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES)
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Cette thse a pour objectif principal examiner comment les Mnon, Platon listes l'anmnesis avec les autres thories qui sont abords dans ce dialogue et, par consquent, essayer de comprendre ce que c'est. Cette recherche vise dans un premier temps situes dans d'autres dialogues de Platon la survenance du terme anamnsis veifique les points qui relient ces oeuvres clarifier la comprhension d'un plus appropri dans le Mnon. Jetez-y aussi, quels sont les lments de la platonicienne thorie de la connaissance sera reliant le dialogue afin de prouver que le Mnon, qui est la question centrale aret, garde un conflit dans la sophistique et la philosophie. Ce choc entre ce qui se passe papapep indirectement par l'intermdiaire de son Mnon enseign, et Socrates qui conteste la thse de l'thique et le relativisme pistmologique. Nous voyons aussi, de quelle manire le dialogue est donne de prendre une voie d'accs au savoir qui est configur comme srs, savoir anmnsis. L'interrogatoire de Mnon depuis le dbut dans les appels d'enquter ristique cet intrt, que lorsqu'ils sont confronts des intrts les amnerait l'tat aportique initial et qui est progressivement remplac par l'aporie fondamental de connaissance, ce n'est point pour aporie la comprhension de anmnesis. En prenant la dialectique comme mthode d'enqute dans le dialogue, il est ncessaire de la part de Socrates et Mnon, de quitter le didaskein et en profiter pour mathsis que la construction des connaissances. Il ouvre de manire un des principaux enjeux dans ce travail examine si le anmnesis permettre l'accs aux moyens et si elle a un statut similaire mnme. un moment o Socrate explique dans le dialogue qui est le anmnesis par monstration monstration fait avec esclave de Mnon il est l'utilisation d'lments mythiques que, selon notre analyse, permettre comprendre le sens de dialogue les connaissances qui montre l'opportunit d'apprendre, qui est la anmnesis
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Water still represents, on its critical properties and phase transitions, a problem of current scientific interest, as a consequence of the countless open questions and of the inadequacy of the existent theoretical models, mainly related to the different solid and liquid phases that this substance possesses. For example, there are 13 known crystalline forms of water, and also amorphous phases. One of them, the amorphous ice of very high density (VHDA), was just recently observed. Other example is the anomalous behavior in the macroscopic density, which presents a maximum at the temperature of 277 K. In order to experimentally investigate the behavior of one of the liquid-solid phase transitions, the anomaly in its density and also the metastability, we used three different cooling techniques and, as comparison systems, we made use of the solvents: acetone and ethyl alcohol. The first studied cooling system employ a Peltier plate, a device recently developed, which makes use of small cubes made up of semiconductors to change heat among two surfaces; the second system is a commercial refrigerator, similar to the residential ones. Finally, the liquid nitrogen technique, which is used to refrigerate the samples in a container, in two ways: a very fast and other one, almost static. In those three systems, three Beckers of aluminum were used (with a volume of 80 ml, each), containing water, alcohol and acetone. They were closed and maintained at atmospheric pressure. Inside of each Becker were installed three thermocouples, disposed along the vertical axis of the Beckers, one close to the inferior surface, other to the medium level and the last one close the superior surface. A system of data acquisition was built via virtual instrumentation using as a central equipment a Data-Acquisition board. The temperature data were collected by the three thermocouples in the three Beckers, simultaneously, in function of freezing time. We will present the behavior of temperature versus freezing time for the three substances. The results show the characterization of the transitions of the liquid
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Coordenao de Aperfeioamento de Pessoal de Nvel Superior
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Classifier ensembles are systems composed of a set of individual classifiers and a combination module, which is responsible for providing the final output of the system. In the design of these systems, diversity is considered as one of the main aspects to be taken into account since there is no gain in combining identical classification methods. The ideal situation is a set of individual classifiers with uncorrelated errors. In other words, the individual classifiers should be diverse among themselves. One way of increasing diversity is to provide different datasets (patterns and/or attributes) for the individual classifiers. The diversity is increased because the individual classifiers will perform the same task (classification of the same input patterns) but they will be built using different subsets of patterns and/or attributes. The majority of the papers using feature selection for ensembles address the homogenous structures of ensemble, i.e., ensembles composed only of the same type of classifiers. In this investigation, two approaches of genetic algorithms (single and multi-objective) will be used to guide the distribution of the features among the classifiers in the context of homogenous and heterogeneous ensembles. The experiments will be divided into two phases that use a filter approach of feature selection guided by genetic algorithm
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New programming language paradigms have commonly been tested and eventually incorporated into hardware description languages. Recently, aspect-oriented programming (AOP) has shown successful in improving the modularity of object-oriented and structured languages such Java, C++ and C. Thus, one can expect that, using AOP, one can improve the understanding of the hardware systems under design, as well as make its components more reusable and easier to maintain. We apply AOP in applications developed using the SystemC library. Several examples will be presented illustrating how to combine AOP and SystemC. During the presentation of these examples, the benefits of this new approach will also be discussed