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EXTRACT (SEE PDF FOR FULL ABSTRACT): Measurements of spatial and temporal distributions of carbon dioxide concentration and carbon-13/carbon-12 ratio in the atmosphere suggest a strong biospheric carbon sink in terrestrial ecosystems. Quantifying the sink, however, has become an enormous challenge for Earth system scientists because of great uncertainties associated with biological variation and environmental heterogeneity in the ecosystems. This paper presents an approach that uses two driving parameters to bound terrestrial carbon sequestration associated with an increase in carbon dioxide concentration.