Alteracións puberais con impacto biopsicosocial : xinecomastia, trastornos da menstruación, acne, escoliose : alertas e estratexias de prevención e intervención. 'Alteraciones puberales con impacto biopsicosocial : ginecomastia, trastornos menstruales, acné, escoliosis : alertas y estrategias de prevención e intervención'.

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O neno maltratado. 'El niño maltratado'.

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Cultura con 'C' en la clase de ELE : propuestas didácticas.

Memoria de máster (Universidad de Salamanca, 2008). Resumen basado en el de la publicación

Adaptación de asignaturas de primer curso de la titulación de Ingeniero de Telecomunicación al Sistema Europeo de Transferencia de Créditos E.C.T.S.

Se adaptan las asignaturas del primer curso de la Ingeniería de Telecomunicaciones al Sistema de Europeo de Transferencia de Créditos ECTS. El plan de estudios no sólo se confecciona teniendo en cuenta el número de horas de clase presenciales, sino que tiene en cuenta el trabajo del alumno fuera de la universidad. Para conocer el trabajo que realiza el alumnado y el profesorado se realiza una encuesta para valorar el trabajo en las distintas carreras y para recabar información que permita seguir mejorando. La encuesta aporta información detallada, repetible y gestionable de forma automática, ya que es una encuesta online que se envía por correo electrónico a todos los profesores y alumnos.

Deontolog??a y c??digo deontol??gico del educador social

Monogr??fico con el t??tulo: 'Educaci??n Social y ??tica profesional'. Resumen basado en el de la publicaci??n

La protecci??n de la infancia en situaciones de riesgo en Am??rica Latina a trav??s de los c??digos de la ni??ez

Monogr??fico con el t??tulo: 'Educaci??n Social y ??tica profesional'. Resumen basado en el de la publicaci??n

Aportaciones de la N.T.I.C. al mundo de la enseñanza y la investigación : Internet y sus aplicaciones en la Historia.

La publicación recoge resumen en Inglés

??C??mo organizar un congreso cient??fico de calidad? : claves y variables del ??xito del XV Congreso Nacional y V Iberoamericano de Pedagog??a

El t??tulo aparece en espa??ol y, a continuaci??n, el t??tulo traducido al ingl??s: ???How to Organize a Quality Scientific Congress? Keys and Variables of Succes of the XV National and V Iberoamerican Congress of Pedagogy'

??C??mo suenan las islas? : taller sobre ecolog??a ac??stica destinado a alumnos de altas capacidades

Se presenta un taller que lleva por t??tulo ?????C??mo suenan las islas???? que fue dise??ado para dar respuesta a la convocatoria del Gobierno de Canarias en el a??o 2009 dentro del programa PREMUN (Programa de Enriquecimiento y Mentor??a Universitaria para el alumnado con altas capacidades intelectuales de Educaci??n Secundaria). En la isla de Lanzarote se programaron cinco talleres destinados a 12 alumnos y alumnas (de 1.?? a 4.?? de la ESO) a desarrollar durante cuatro s??bados durante los meses de abril y mayo. Se profundiz?? en la ecoac??stica para sumergir al alumnado en la complejidad del paisaje sonoro, para intervenir en ??l buscando el bienestar de cuantos habitamos el planeta (incluidos los animales).

??C??mo construir un plan de lectura y escritura de centro?

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La teoría del aprendizaje significativo de David Ausubel en la aplicación de los textos de estudios sociales proporcionados por el Ministerio de Educación a los octavos años del Colegio Técnico Referencial "Luis Fernando Ruiz" de Latacunga, provincia de Cotopaxi, en el año lectivo 2012-2013

En momentos en que la principal preocupación es mejorar la calidad del aprendizaje (enseñanza de calidad), el docente debe encontrar los medios más efectivos para alcanzar los objetivos educativos y de esta manera lograr un aprendizaje significativo. El concepto de aprendizaje significativo fue desarrollado por David Ausubel para tratar de comprender desde el punto de la psicología, como se produce el aprendizaje en el sujeto, así como sus limitaciones para lo cual relacionó las prácticas educativas de entonces con su teoría. El proceso demanda, además de la mediación efectiva del docente, del apoyo de materiales educativos que a decir de Ausubel son parte fundamental en el proceso del aprendizaje significativo, en este caso el material potencialmente significativo. Esta investigación efectúa un análisis de un texto escolar de Estudios sociales para octavo año, con el fin de establecer si este permite o dificulta el aprendizaje significativo en el contexto de la reflexión teórica de Ausubel. Aunque el objeto de estudio es el texto de trabajo de los estudiantes, se utilizó como referente del aprendizaje a docentes y estudiantes del Colegio Técnico Referencial “Luis Fernando Ruiz con el fin de lograr una mejor estimación de la efectividad del texto para apoyar el aprendizaje.

Different mechanisms underlie the effects of acute and long-term inhibition of nitric oxide synthases in antigen-induced pulmonary eosinophil recruitment in BALB/C mice

Nitric oxide synthase (NOS) inhibitors are largely used to evaluate the NO contribution to pulmonary allergy, but contrasting data have been reported. In this study, pharmacological, biochemical and pharmacokinetic assays were performed to compare the effects of acute and long-term treatment of BALB/C mice with the non-selective NOS inhibitor L-NAME in ovalbumin (OVA)-challenged mice. Acute L-NAME treatment (50 mg/kg, gavage) significantly reduced the eosinophil number in bronchoalveolar lavage fluid (BALF). The inducible NOS (iNOS) inhibitor aminoguanidine (20 mg/kg/day in the drinking water) also significantly reduced the eosinophil number in BALF In contrast, 3-week L-NAME treatment (50 and 150 mg/kg/day in the drinking water) significantly increased the pulmonary eosinophil influx. The constitutive NOS (cNOS) activity in brain and lungs was reduced by both acute and 3-week L-NAME treatments. The pulmonary iNOS activity was reduced by acute L-NAME (or aminoguanidine), but unaffected by 3-week L-NAME treatment. Acute L-NAME (or aminoguanidine) treatment was more efficient to reduce the NO(x) levels compared with 3-week L-NAME treatment. The pharmacokinetic study revealed that L-NAME is not bioavailable when given orally. After acute L-NAME intake, serum concentrations of the metabolite N(omega)-nitro-L-arginine decreased from 30 min to 24 h. In the 3-week L-NAME treatment, the N(omega)-nitro-L-arginine concentration was close to the detection limit. In conclusion, 3-week treatment with L-NAME yields low serum N(omega)-nitro-L-arginine concentrations, causing preferential inhibition of cNOS activity. Therefore, eosinophil influx potentiation by 3-week L-NAME treatment may reflect removal of protective cNOS-derived NO, with no interference on the ongoing inflammation due to iNOS-derived NO. (c) 2008 Elsevier Ltd. All rights reserved.

p53 Mutant Human Glioma Cells Are Sensitive to UV-C-Induced Apoptosis Due to Impaired Cyclobutane Pyrimidine Dimer Removal

The p53 protein is a key regulator of cell responses to DNA damage, and it has been shown that It sensitizes glioma cells to the alkylating agent temozolomide by up-regulating the extrinsic apoptotic pathway, whereas it increases the resistance to chloroethylating agents, such as ACNU and BCNU, probably by enhancing the efficiency of DNA repair. However, because these agents induce a wide variety of distinct DNA lesions, the direct Importance of DNA repair is hard to access. Here, it is shown that the Induction of photoproducts by UV light (UV-C) significantly Induces apoptosis In a p53-mutated glioma background. This Is caused by a reduced level of photoproduct repair, resulting In the persistence of DNA lesions in p53-mutated glioma cells. UV-C-Induced apoptosis in p53 mutant glioma cells Is preceded by strong transcription and replication inhibition due to blockage by unrepaired photolesions. Moreover, the results Indicate that UV-C-induced apoptosis of p53 mutant glioma cells Is executed through the intrinsic apoptotic pathway, with Bcl-2 degradation and sustained Bax and Bak up-regulation. Collectively, the data Indicate that unrepaired DNA lesions Induce apoptosis In p53 mutant gliomas despite the resistance of these gliomas to temozolomide, suggesting that efficiency of treatment of p53 mutant gliomas might be higher with agents that Induce the formation of DNA lesions whose global genomic repair is dependent on p53. (Mol Cancer Res 2009;7(2):237-46)

Occupational exposure to radon and natural gamma radiation in the La Carolina, a former gold mine in San Luis Province, Argentina

Radon and gamma radiation level measurements were carried out inside the La Carolina mine, one of the oldest gold mining camps of southern South America, which is open for touristic visits nowadays. CR-39 track-etch detectors and thermoluminescent dosimeters of natural CaF(2) and LiF TLD-100 were exposed at 14 points along the mine tunnels in order to estimate the mean (222)Rn concentration and the ambient dose equivalent during the summer season (November 2008 to February 2009). The values for the (222)Rn concentration at each monitoring site ranged from 1.8 +/- 0.1 kBq m(-3) to 6.0 +/- 0.5 kBq m(-3), with a mean value of 4.8 kBq m(-3), indicating that these measurements exceed in about three times the upper action level recommended by ICRP for workplaces. The correlations between radon and gamma radiation levels inside the mine were also investigated. Effective doses due to (222)Rn and gamma rays inside the mine were determined, resulting in negligible values to tourists. Considering the effective dose to the mine tourist guides, values exceeding 20 mSv of internal contribution to the effective doses can be reached, depending on the number of working hours inside the mine. (C) 2009 Elsevier Ltd. All rights reserved.

Petrology and geochemistry of the banded iron formation in the Eastern Sierras Pampeanas of San Luis (Argentina): Implications for the evolution of the Nogoli Metamorphic Complex

The metamorphosed banded iron formation from the Nogoli Metamorphic Complex of western Sierra de San Luis, Eastern Sierras Pampeanas of Argentina (Nogoli area, 32 degrees 55`S-66 degrees 15`W) is classified as an oxide facies iron formation of Algoma Type, with a tectonic setting possibly associated with an island arc or back arc, on the basis of field mapping, mineral and textural arrangements and whole rock geochemical features. The origin of banded iron formation is mainly related to chemical precipitation of hydrogenous sediments from seawater in oceanic environments. The primary chemical precipitate is a result of solutions that represent mixtures of seawater and hydrothermal fluids, with significant dilution by maficultramafic volcanic and siliciclastic materials. Multi-stage T(DM) model ages of 1670, 1854 and 1939 Ma and positive, mantle-like xi Nd((1502)) values of +3.8, +1.5 and +0.5 from the banded iron formation are around the range of those mafic to ultramafic meta-volcanic rocks of Nogoli Metamorphic Complex, which are between 1679 and 1765 Ma and +2.64 and +3.68, respectively. This Sm and Nd isotopic connection suggests a close genetic relationship between ferruginous and mafic-ultramafic meta-volcanic rocks, as part of the same island arc or back arc setting. A previous Sm-Nd whole rock isochron of similar to 1.5 Ga performed on mafic-ultramafic meta-volcanic rocks led to the interpretation that chemical sedimentation as old as Mesoproterozoic is possible for the banded iron formation. A clockwise P-T path can be inferred for the regional metamorphic evolution of the banded iron formation, with three distinctive trajectories: (1) Relict prograde M(1)-M(3) segment with gradual P and T increase from greenschist facies at M(1) to amphibolite facies at M(3). (2) Peak P-T conditions at high amphibolite-low granulite facies during M(4). (3) Retrograde counterpart of M(4), that returns from amphibolite facies and stabilizes at greenschist facies during M(5). Each trajectory may be regarded as produced by different tectonic events related to the Pampean? (1) and the Famatinian (2 and 3) orogenies, during the Early to Middle Paleozoic. The Nogoli Metamorphic Complex is interpreted as part of a greenstone belt within the large Meso- to Neoproterozoic Pampean Terrane of the Eastern Sierras Pampeanas of Argentina. (C) 2009 Elsevier Ltd. All rights reserved.