An??lisis metacognitivo de protocolos en tareas de estimaci??n : una reflexi??n sobre el car??cter estrat??gico de los procedimientos de c??lculo

Resumen tomado de la publicaci??n. IV n??mero monogr??fico con el t??tulo: VII Seminario de Investigaci??n y pensamiento num??rico y algebraico (PNA).

Consideraciones metodológicas y organizativas para el desarrollo de videoconferencias con metodología C.L.I.L. en el marco de la convergencia europea.

Resumen basado en el de la publicación

La integraci??n de personas con discapacidad en la Educaci??n de Adultos

Conocer c??mo se est?? llevando a cabo la integraci??n de personas con discapacidad en Educaci??n de Personas Adultas (EPA) en la regi??n de Murcia. Explorar la situaci??n y las creencias que el profesorado de EPA de la regi??n de Murcia tiene sobre su trabajo y sus ense??anzas. Analizar las opiniones del alumnado discapacitado de las Asociaciones-Centros de EPA de Murcia con respecto a diferentes aspectos de su contexto personal, familiar, social y educativo. Dise??ar una propuesta de trabajo que favorezca la adquisici??n por parte de las personas adultas con necesidades educativas especiales de los contenidos previstos en el curriculum del nivel educativo en el que se encuentran integradas. 12 alumnos-as discapacitados integrados en cuatro centros de adultos de la Regi??n de Murcia, 4 directivos y 16 profesores-as de tales centros. Se recoge el marco te??rico de la Educaci??n de las Personas Adultas y la Educaci??n Especial. Se selecciona la muestra y se dise??an los instrumentos de recogida de informaci??n: cuestionarios al profesorado y directivos, entrevistas al profesorado y alumnado, notas de campo y cuestionario sociom??trico a los alumnos-as. Para el an??lisis de los datos, se procede a una exploraci??n cuantitativa mediante an??lisis descriptivos de las variables y a un tratamiento cualitativo mediante an??lisis de contenido de la informaci??n. Se analizan los resultados para cada objetivo propuesto. Porcentajes. Se observa que la mayor??a del profesorado opina que: la legislaci??n sobre EPA es demasiado te??rica y poco realista, las ofertas de formaci??n actuales son escasas, se deben tomar medidas sobre la estabilidad del profesorado a todos los niveles y dotarles de una formaci??n espec??fica en educaci??n de adultos. Se necesita la articulaci??n de un curriculum espec??fico para los centros de EPA que contemple la integraci??n de alumnos-as discapacitados seg??n los principios de normalizaci??n y educaci??n permanente. Se concluye la necesidad de una revisi??n del marco legal de la EPA y se recomienda seguir profundizando en esta l??nea de investigaci??n para dar respuesta a las demandas y prioridades actuales de la EPA en la Regi??n de Murcia.

C??mo mejorar la visi??n de los organismos acreditadores mexicanos, sobre la importancia de la acci??n tutorial

Monogr??fico con el t??tulo: "Orientaci??n en acci??n"

Ciencia con luz propia : aplicaciones tecnol??gicas de la luz : unidad did??ctica

Resumen basado en el de la publicaci??n

El espa??ol en Jap??n : qu?? y c??mo se ense??a

Resumen basado en el de la publicaci??n

La Cultura científica en infantil: el desarrollo de competencias en la formación inicial de maestros

La vinculación teoría práctica en la formación de maestros es un tema recurrente al que se le viene prestando atención desde hace décadas en todo el mundo. En la Facultad de Educación y Humanidades de Melilla, se realizan prácticas externas previas al Practicum, orientadas desde las materias de 1º y 2º curso (el Practicum se desarrolla concentrado en el último cuatrimestre de 3º). Este tipo de prácticas que denominamos “Prácticas de C��tedra”, se desarrollan actualmente como proyectos de innovación docente acogidos a las convocatorias de la Universidad de Granada, (Proyecto de Innovación Docente 08/92) y cuentan con una cierta tradición (Sánchez, Cabo y Granda, 1990)

Astrophysical S factors for fusion reactions involving C, O, Ne, and Mg isotopes

Using the Sao Paulo potential and the barrier penetration formalism we have calculated the astrophysical factor S(E) for 946 fusion reactions involving stable and neutron-rich isotopes of C, O, Ne, and Mg for center-of-mass energies E varying from 2 to approximate to 18-30 MeV (covering the range below and above the Coulomb barrier). We have parameterized the energy dependence, S(E), by an accurate universal 9-parameter analytic expression and present tables of fit parameters for all the reactions. We also discuss the reduced 3-parameter version of our fit which is highly accurate at energies below the Coulomb barrier, and outline the procedure for calculating the reaction rates. The results can be easily converted to thermonuclear or pycnonuclear reaction rates to simulate various nuclear burning phenomena, in particular, stellar burning at high temperatures and nucleosynthesis in high density environments. (C) 2010 Elsevier Inc. All rights reserved

A Single Mutation at the Sheet Switch Region Results in Conformational Changes Favoring lambda 6 Light-Chain Fibrillogenesis

Systemic amyloid light-chain (LC) amyloidosis is a disease process characterized by the pathological deposition of monoclonal LCs in tissue. All LC subtypes are capable of fibril formation although lambda chains, particularly those belonging to the lambda 6 type, are overrepresented. Here, we report the thermodynamic and in vitro fibrillogenic properties of several mutants of the lambda 6 protein 6aJL2 in which Pro7 and/or His8 was substituted by Ser or Pro. The H8P and H8S mutants were almost as stable as the wildtype protein and were poorly fibrillogenic. In contrast, the P7S mutation decreased the thermodynamic stability of 6aJL2 and greatly enhanced its capacity to form amyloid-like fibrils in vitro. The crystal structure of the P7S mutant showed that the substitution induced both local and long-distance effects, such as the rearrangement of the V(L) (variable region of the light chain)-V(L) interface. This mutant crystallized in two orthorhombic polymorphs, P2(1)2(1)2(1) and C222(1). In the latter, a monomer that was not arranged in the typical Bence-Jones dimer was observed for the first time. Crystal-packing analysis of the C222(1) lattice showed the establishment of intermolecular beta-beta interactions that involved the N-terminus and beta-strand B and that these could be relevant in the mechanism of LC fibril formation. Our results strongly suggest that Pro7 is a key residue in the conformation of the N-terminal sheet switch motif and, through long-distance interactions, is also critically involved in the contacts that stabilized the V(L) interface in lambda 6 LCs. (C) 2009 Elsevier Ltd. All rights reserved.

Study of the enthalpy-entropy mechanism from water sorption of orange seeds (C. sinensis cv. Brazilian) for the use of agro-industrial residues as a possible source of vegetable oil production

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

ARE CORPORAL ALLOMETRIC MEASUREMENTS GOOD PREDICTORS of PALATABILITY IN NEOTROPICAL BUTTERFLIES (LEPIDOPTERA)?

Since palatable butterflies are more dependent on evasive flight to escape from predators, they should be more restricted in their flight-related morphology than unpalatable ones. We compared: the ratios between the (1) length of head plus thorax and the length of abdomen (A/B), (2) length of the tip of the head to wing base and the length of the wing base to end of the abdomen (C/D), (3) the variances of A/B and C/D, (4) the proportion between the thoracic and the body weight, and (5) the flight speed between palatable and unpalatable butterflies. A/B and thoracic/body weight were higher for palatable species, indicating higher body symmetry and muscular mass. However, flight speed did not differ. Unexpectedly, the variance of A/B was higher for palatable species while that of C/D did not differ. Therefore, corporal allometric measurements of Neotropical butterflies are good predictors of palatability, though not of flight speed.

Concentração sérica da proteína C reativa como indicador preditivo do prognóstico clínico em indivíduos com hemorragia subaracnóidea aneurísmática

Pós-graduação em Bases Gerais da Cirurgia - FMB

C-reactive protein and vasospasm after aneurysmal subarachnoid hemorrhage1

PURPOSE:To evaluate the relationship between C reactive protein levels and clinical and radiological parameters with delayed ischemic neurological deficits and outcome after aneurysmal subarachnoid hemorrhage.METHODS:One hundred adult patients with aneurismal SAH were prospectively evaluated. Besides the baseline characteristics, daily C-reactive protein levels were prospectively measured until day 10 after subarachnoid hemorrhage. The primary end point was outcome assessed by Glasgow Outcome Scale, the secondary was the occurrence of delayed ischemic neurological deficits (DINDs).RESULTS:A progressive increase in the CRP levels from the admission to 3rd postictal day was observed, followed by a slow decrease until the 9th day. Hemodynamic changes in TCD were associated with higher serum CRP levels. Patients with lower GCS scores presented with increased CRP levels. Patients with higher Hunt and Hess grades on admission developed significantly higher CRP serum levels. Patients with higher admission Fisher grades showed increased levels of CRP. A statistically significant inverse correlation was established in our series between CRP serum levels and GOS on discharge and CRP levels.CONCLUSIONS:Higher C-reactive protein serum levels are associated with worse clinical outcome and the occurrence of delayed ischemic neurological deficits. Because C-reactive protein levels were significantly elevated in the early phase, they might be a useful parameter to monitor.

Predicting vasospasm after aneurismal subarachnoid hemorrhage with C reactive protein levels

Aim: The interest of inflammatory marker increased in the last years, even in preventing clinical outcome after subarachnoid hemorrhage (SAH). Our objective was to study the relationships between C-reactive protein levels and clinical outcome and the development of cerebral vasospasm after aneurismal SAH. Methods: One hundred adult patients with aneurismal SAH were prospectively evaluated. Glasgow Coma Scale (GCS) score, Hunt and Hess grade, Fisher grade, CT scans, digital subtraction angiography studies, transcranial doppler (TCD) and daily neurological examinations were recorded. Serial serum CRP measurements were obtained on daily between admission and 10th days. Glasgow Outcome Scale (GOS) and the modified Rankin Scale (mRS) were used to predict outcome. Results: A progressive increase in the CRP levels from the admission to the 3rd postictal day was observed, followed by a slow decrease until the 9th day. Hemodynamic changes in TCD were associated with higher serum CRP levels. Patients with lower GCS scores presented with increased CRP levels. Patients with higher Hunt and Hess grades on admission developed significantly higher CRP serum levels. Patients with higher admission Fisher grades showed increased levels of CRP. A statistically significant inverse correlation was established in our series between CRP serum levels and GOS and mRS scores on discharge and CRP levels. Conclusion: Increased CRP levels were strongly associated with poor clinical outcome. CRP levels can predict cerebral vasospasm and delayed ischemic deficits with higher statistic significance. There are relationships between hemodynamic chances in TCD and higher CRP levels.

Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage

Objectives: Our aim was to evaluate the relationship between serum C-reactive protein (CRP) levels and the neurological prognosis and development of vasospasm in patients with aneurysmal subarachnoid hemorrhage (aSAH). Methods: Eighty-two adult patients with aSAH diagnoses were prospectively evaluated. Glasgow Coma Scale (GCS) score, Hunt and Hess grade, Fisher grade, cranial CT scans, digital subtraction angiography studies and daily neurological examinations were recorded. Serial serum CRP measurements were obtained daily between admission and the tenth day. Glasgow Outcome Scale (GOS) and the modified Rankin Scale (mRS) were used to assess the prognosis. Results: Serum CRP levels were related to severity of aSAH. Patients with lower GCS scores and higher Hunt and Hess and Fisher grades presented statistically significant higher serum CRP levels. Patients with higher serum CRP levels had a less favorable prognosis. Conclusions: Increased serum CRP levels were strongly associated with worse clinical prognosis in this study.