968 resultados para Andrés Pérez, Martin de


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Mode of access: Internet.

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Corabastos es la central mayorista de alimentos más grande de Colombia. El reportaje radial cuenta la historia de tres personajes disímiles de esa gran ciudad, retratando el entorno de la misma, sus problemas y cómo, de acuerdo a sus ingresos, se contrastan sus vidas.

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Resumen basado en el que aporta la revista.

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Existe un ejemplar editado en 1991 con signatura EC 60355

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El proyecto ha consistido en la realización de una página web del centro donde se muestra la realidad de este colegio y de sus sedes, las diversas actividades que se realizan, etc. Esta página web es de acceso público. Por otra parte, se ha realizado un espacio virtual al que pueden acceder sólo los profesores del centro, previa identificación, para descargarse documentos relativos al funcionamiento del colegio. Se trata de un colegio rural agrupado formado por seis centros en pedanías de Lorca que algunas distan entre sí más de 35 kilómetros. La página web que conecta los centros y permite intercambiar información con toda la comunidad educativa así como hacerse oír en el exterior..

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El artículo está incluido en un número monográfico especial con los trabajos del I Simposio Pluridisciplinar sobre Diseño, Evaluación y Descripción de Contenidos Educativos Reutilizables (Guadalajara, Octubre 2004).Resumen basado en el de la publicación

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The voltage- and Ca2+-activated K+ (KV,Ca) channel is expressed in a variety of polarized epithelial cells seemingly displaying a tissue-dependent apical-to-basolateral regionalization, as revealed by electrophysiology. Using domain-specific biotinylation and immunofluorescence we show that the human channel KV,Ca α-subunit (human Slowpoke channel, hSlo) is predominantly found in the apical plasma membrane domain of permanently transfected Madin-Darby canine kidney cells. Both the wild-type and a mutant hSlo protein lacking its only potential N-glycosylation site were efficiently transported to the cell surface and concentrated in the apical domain even when they were overexpressed to levels 200- to 300-fold higher than the density of intrinsic Slo channels. Furthermore, tunicamycin treatment did not prevent apical segregation of hSlo, indicating that endogenous glycosylated proteins (e.g., KV,Ca β-subunits) were not required. hSlo seems to display properties for lipid-raft targeting, as judged by its buoyant distribution in sucrose gradients after extraction with either detergent or sodium carbonate. The evidence indicates that the hSlo protein possesses intrinsic information for transport to the apical cell surface through a mechanism that may involve association with lipid rafts and that is independent of glycosylation of the channel itself or an associated protein. Thus, this particular polytopic model protein shows that glycosylation-independent apical pathways exist for endogenous membrane proteins in Madin-Darby canine kidney cells.

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Acknowledgements. This work is dedicated to the memory of Andrés Pérez-Estaún, brilliant scientist, colleague, and friend. The authors sincerely thank Ian Ferguson and an anonymous reviewer for their useful comments on the manuscript. Xènia Ogaya is currently supported in the Dublin Institute for Advanced Studies by a Science Foundation Ireland grant IRECCSEM (SFI grant 12/IP/1313). Juan Alcalde is funded by NERC grant NE/M007251/1, on interpretational uncertainty. Juanjo Ledo, Pilar Queralt and Alex Marcuello thank Ministerio de Economía y Competitividad and EU Feder Funds through grant CGL2014- 54118-C2-1-R. Funding for this Project has been partially provided by the Spanish Ministry of Industry, Tourism and Trade, through the CIUDEN-CSIC-Inst. Jaume Almera agreement (ALM-09-027: Characterization, Development and Validation of Seismic Techniques applied to CO2 Geological Storage Sites), the CIUDEN-Fundació Bosch i Gimpera agreement (ALM-09-009 Development and Adaptation of Electromagnetic techniques: Characterisation of Storage Sites) and the project PIERCO2 (Progress In Electromagnetic Research for CO2 geological reservoirs CGL2009-07604). The CIUDEN project is co-financed by the European Union through the Technological Development Plant of Compostilla OXYCFB300 Project (European Energy Programme for Recovery).

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La coalición de fuerzas políticas que sostuvo el gobierno Fernando Henrique Cardoso durante cerca de ocho años entró definitivamente en crisis. El origen de esta crisis se encuentra en el agotamiento de una política económica que parecía exitosa en su comienzo pero que llevó de hecho el país a una de las más graves crisis de su historia.Esta fue la historia de las experiencias neoliberales de los años 90. Salinas duró seis años de esplendor, hasta la crisis del 94. Menen alcanzó reelegirse una vez pero no logró la segunda reelección hasta que su país entró en la dramática crisis actual. Fujimori también logró una reelección y cayó cuando quiso imponer su tercer mandato. En Venezuela la crisis explotó en el “Caracazo”, con Andrés Pérez en el gobierno, pero fue suplantada con más diez años de consenso neoliberal, que ganó la mayoría de la izquierda y pasó el bastión de la oposición al líder del intento insurreccional que se ligara al “Caracazo”: Hugo Chávez.

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Effective and targeted conservation action requires detailed information about species, their distribution, systematics and ecology as well as the distribution of threat processes which affect them. Knowledge of reptilian diversity remains surprisingly disparate, and innovative means of gaining rapid insight into the status of reptiles are needed in order to highlight urgent conservation cases and inform environmental policy with appropriate biodiversity information in a timely manner. We present the first ever global analysis of extinction risk in reptiles, based on a random representative sample of 1500 species (16% of all currently known species). To our knowledge, our results provide the first analysis of the global conservation status and distribution patterns of reptiles and the threats affecting them, highlighting conservation priorities and knowledge gaps which need to be addressed urgently to ensure the continued survival of the world’s reptiles. Nearly one in five reptilian species are threatened with extinction, with another one in five species classed as Data Deficient. The proportion of threatened reptile species is highest in freshwater environments, tropical regions and on oceanic islands, while data deficiency was highest in tropical areas, such as Central Africa and Southeast Asia, and among fossorial reptiles. Our results emphasise the need for research attention to be focussed on tropical areas which are experiencing the most dramatic rates of habitat loss, on fossorial reptiles for which there is a chronic lack of data, and on certain taxa such as snakes for which extinction risk may currently be underestimated due to lack of population information. Conservation actions specifically need to mitigate the effects of human-induced habitat loss and harvesting, which are the predominant threats to reptiles.