1000 resultados para SEMI-IPN


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Context. To date, the CoRoT space mission has produced more than 124 471 light curves. Classifying these curves in terms of unambiguous variab ility behavior is mandatory for obtaining an unbi ased statistical view on th eir controlling root-causes. Aims. The present study provides an overview of semi-sinusoidal light curves observed by the CoRoT exo-field CCDs. Methods. We selected a sample of 4206 light curves presenting well-defined semi-si nusoidal signatures. Th e variability periods were computed based on Lomb-Scargle periodograms, harmonic fits, and visual inspection. Results. Color–period diagrams for the present sample show the trend of an increase of the variability periods as long as the stars evolve. This evolutionary behavior is also noticed when comparing the period distribution in the Galactic center and anti-center directions. These aspect s indicate a compatibility with stellar rotation, although more inform ation is needed to confirm their root- causes. Considering this possi bility, we identified a subset of th ree Sun-like candidates by their photometric peri od. Finally, the variability period versus color diagr am behavior was found to be highly depe ndent on the reddening correction.

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Objetivo: Identificar os diagnósticos de enfermagem em cuidadores de crianças com fissura orofaciais e anomalias relacionadas, internadas em unidade de cuidado semi-intensivo. Método: Estudo prospectivo, realizado na unidade de terapia semi-intensiva do Hospital de Reabilitação de Anomalias Craniofaciais da Universidade de São Paulo, nos meses de maio e junho de 2013. A amostra constou de 20 cuidadores. O critério de inclusão foi à adesão. Por meio da entrevista estruturada, os participantes foram avaliados em dois momentos distintos: na internação da criança e na alta hospitalar. Os diagnósticos foram formalizados segundo a taxonomia da NANDAInternacional, com enfoque psicossocial. Resultados: A amostra foi composta exclusivamente por mães, com idade média de 28,35 anos, ensino médio completo (60%), classe social média (60%), com união estável (75%) e moradia própria (75%). No momento da internação prevaleceram: o domínio papéis e relacionamentos (22%); a classe papéis do cuidador (85%), e os DE: tensão do papel de cuidador (100%), ansiedade (100%), disposição para o conhecimento aumentado (85%), disposição para controle aumentado do regime terapêutico (80%) e padrão de sono prejudicado (55%). No momento da alta prevaleceram: o domínio enfrentamento/tolerância ao estresse (33%); a classe respostas de enfrentamento (72%), e os DE: disposição para maternidade melhorada (50%), disposição para enfrentamento aumentada (50%), disposição para enfrentamento familiar aumentado (50%). Conclusão: Embora inicialmente os cuidadores tenham apresentado estresse, possivelmente devido à necessidade do aprendizado para a manutenção dos cuidados após a alta hospitalar, evidenciou-se posteriormente uma progressão em relação à aceitação situacional/enfrentamento.

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Semi-supervised learning is a classification paradigm in which just a few labeled instances are available for the training process. To overcome this small amount of initial label information, the information provided by the unlabeled instances is also considered. In this paper, we propose a nature-inspired semi-supervised learning technique based on attraction forces. Instances are represented as points in a k-dimensional space, and the movement of data points is modeled as a dynamical system. As the system runs, data items with the same label cooperate with each other, and data items with different labels compete among them to attract unlabeled points by applying a specific force function. In this way, all unlabeled data items can be classified when the system reaches its stable state. Stability analysis for the proposed dynamical system is performed and some heuristics are proposed for parameter setting. Simulation results show that the proposed technique achieves good classification results on artificial data sets and is comparable to well-known semi-supervised techniques using benchmark data sets.

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A detailed characterization of a X-ray Si(Li) detector was performed to obtain the energy dependence of efficiency in the photon energy range of 6.4 - 59.5 keV. which was measured and reproduced by Monte Carlo (MC) simulations. Significant discrepancies between MC and experimental values were found when lhe manufacturer parameters of lhe detector were used in lhe simulation. A complete Computerized Tomagraphy (CT) detector scan allowed to find the correct crystal dimensions and position inside the capsule. The computed efficiencies with the resulting detector model differed with the measured values no more than 10% in most of the energy range.

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Improvements in on-farm water and soil fertility management through water harvesting may prove key to up-grade smallholder farming systems in dry sub-humid and semi-arid sub-Sahara Africa (SSA). The currently experienced yield levels are usually less than 1 t ha-1, i.e., 3-5 times lower than potential levels obtained by commercial farmers and researchers for similar agro-hydrological conditions. The low yield levels are ascribed to the poor crop water availability due to variable rainfall, losses in on-farm water balance and inherently low soil nutrient levels. To meet an increased food demand with less use of water and land in the region, requires farming systems that provide more yields per water unit and/or land area in the future. This thesis presents the results of a project on water harvesting system aiming to upgrade currently practised water management for maize (Zea mays, L.) in semi-arid SSA. The objectives were to a) quantify dry spell occurrence and potential impact in currently practised small-holder grain production systems, b) test agro-hydrological viability and compare maize yields in an on-farm experiment using combinations supplemental irrigation (SI) and fertilizers for maize, and c) estimate long-term changes in water balance and grain yields of a system with SI compared to farmers currently practised in-situ water harvesting. Water balance changes and crop growth were simulated in a 20-year perspective with models MAIZE1&2. Dry spell analyses showed that potentially yield-limiting dry spells occur at least 75% of seasons for 2 locations in semi-arid East Africa during a 20-year period. Dry spell occurrence was more frequent for crop cultivated on soil with low water-holding capacity than on high water-holding capacity. The analysis indicated large on-farm water losses as deep percolation and run-off during seasons despite seasonal crop water deficits. An on-farm experiment was set up during 1998-2001 in Machakos district, semi-arid Kenya. Surface run-off was collected and stored in a 300m3 earth dam. Gravity-fed supplemental irrigation was carried out to a maize field downstream of the dam. Combinations of no irrigation (NI), SI and 3 levels of N fertilizers (0, 30, 80 kg N ha-1) were applied. Over 5 seasons with rainfall ranging from 200 to 550 mm, the crop with SI and low nitrogen fertilizer gave 40% higher yields (**) than the farmers’ conventional in-situ water harvesting system. Adding only SI or only low nitrogen did not result in significantly different yields. Accounting for actual ability of a storage system and SI to mitigate dry spells, it was estimated that a farmer would make economic returns (after deduction of household consumption) between year 2-7 after investment in dam construction depending on dam sealant and labour cost used. Simulating maize growth and site water balance in a system of maize with SI increased annual grain yield with 35 % as a result of timely applications of SI. Field water balance changes in actual evapotranspiration (ETa) and deep percolation were insignificant with SI, although the absolute amount of ETa increased with 30 mm y-1 for crop with SI compared to NI. The dam water balance showed 30% productive outtake as SI of harvested water. Large losses due to seepage and spill-flow occurred from the dam. Water productivity (WP, of ETa) for maize with SI was on average 1 796 m3 per ton grain, and for maize without SI 2 254 m3 per ton grain, i.e, a decerase of WP with 25%. The water harvesting system for supplemental irrigation of maize was shown to be both biophysically and economically viable. However, adoption by farmers will depend on other factors, including investment capacity, know-how and legislative possibilities. Viability of increased water harvesting implementation in a catchment scale needs to be assessed so that other down-stream uses of water remains uncompromised.

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The need for a convergence between semi-structured data management and Information Retrieval techniques is manifest to the scientific community. In order to fulfil this growing request, W3C has recently proposed XQuery Full Text, an IR-oriented extension of XQuery. However, the issue of query optimization requires the study of important properties like query equivalence and containment; to this aim, a formal representation of document and queries is needed. The goal of this thesis is to establish such formal background. We define a data model for XML documents and propose an algebra able to represent most of XQuery Full-Text expressions. We show how an XQuery Full-Text expression can be translated into an algebraic expression and how an algebraic expression can be optimized.

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Camptothecin, (CPT) is a pentacyclic alkaloid isolated for the first time from the Chinese tree Camptotheca acuminata, and which has soon attracted the attention of medicinal chemists and pharmacologists due to its promising anti-cancer activity against the most aggressive histo-types. So far, most of the synthesized camptothecin analogues are A and B ring modified compounds, which have been prepared via synthetic or semi-synthetic routes. To the best of our knowledge, a very limited number of C, D, or E ring modified analogues of CPT have been reported; moreover, the few derivatives known from the literature showed a reduced or no biological activity. This dissertation presents synthetic studies on camptothecin new derivatives along with the development of a new and general semi-synthetic methodology to obtain a large variety of analogues. We report here the semi-synthesis of a new family of 5-substituted CPT's, along with their biological activity evaluation, which will be compared with reference compounds. The use of carrier-linked prodrugs has emerged as a useful strategy to overcome some of the drawbacks related with the use of the parent drug, such as low solubility, membrane permeability properties, low oral absorption, instability, toxicity, and nontargeting. Herein we report CPT-prodrugs synthesized via ring opening of the lactone moiety as 17-O-acyl camptothecin tripartate conjugates, which bear a polyamine side chain with different architectures, as the carriers. Moreover, we found that the replacement of the oxygen atom with sulphur on the piridone D-ring, dramatically improves the potency of the novel 16a-thio-camptothecin derivatives, opening new possibilities in the modelling of this class of compounds.

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This thesis is about three major aspects of the identification of top quarks. First comes the understanding of their production mechanism, their decay channels and how to translate theoretical formulae into programs that can simulate such physical processes using Monte Carlo techniques. In particular, the author has been involved in the introduction of the POWHEG generator in the framework of the ATLAS experiment. POWHEG is now fully used as the benchmark program for the simulation of ttbar pairs production and decay, along with MC@NLO and AcerMC: this will be shown in chapter one. The second chapter illustrates the ATLAS detectors and its sub-units, such as calorimeters and muon chambers. It is very important to evaluate their efficiency in order to fully understand what happens during the passage of radiation through the detector and to use this knowledge in the calculation of final quantities such as the ttbar production cross section. The last part of this thesis concerns the evaluation of this quantity deploying the so-called "golden channel" of ttbar decays, yielding one energetic charged lepton, four particle jets and a relevant quantity of missing transverse energy due to the neutrino. The most important systematic errors arising from the various part of the calculation are studied in detail. Jet energy scale, trigger efficiency, Monte Carlo models, reconstruction algorithms and luminosity measurement are examples of what can contribute to the uncertainty about the cross-section.

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A broad variety of solid state NMR techniques were used to investigate the chain dynamics in several polyethylene (PE) samples, including ultrahigh molecular weight PEs (UHMW-PEs) and low molecular weight PEs (LMW-PEs). Via changing the processing history, i.e. melt/solution crystallization and drawing processes, these samples gain different morphologies, leading to different molecular dynamics. Due to the long chain nature, the molecular dynamics of polyethylene can be distinguished in local fluctuation and long range motion. With the help of NMR these different kinds of molecular dynamics can be monitored separately. In this work the local chain dynamics in non-crystalline regions of polyethylene samples was investigated via measuring 1H-13C heteronuclear dipolar coupling and 13C chemical shift anisotropy (CSA). By analyzing the motionally averaged 1H-13C heteronuclear dipolar coupling and 13C CSA, the information about the local anisotropy and geometry of motion was obtained. Taking advantage of the big difference of the 13C T1 relaxation time in crystalline and non-crystalline regions of PEs, the 1D 13C MAS exchange experiment was used to investigate the cooperative chain motion between these regions. The different chain organizations in non-crystalline regions were used to explain the relationship between the local fluctuation and the long range motion of the samples. In a simple manner the cooperative chain motion between crystalline and non-crystalline regions of PE results in the experimentally observed diffusive behavior of PE chain. The morphological influences on the diffusion motion have been discussed. The morphological factors include lamellar thickness, chain organization in non-crystalline regions and chain entanglements. Thermodynamics of the diffusion motion in melt and solution crystallized UHMW-PEs is discussed, revealing entropy-controlled features of the chain diffusion in PE. This thermodynamic consideration explains the counterintuitive relationship between the local fluctuation and the long range motion of the samples. Using the chain diffusion coefficient, the rates of jump motion in crystals of the melt crystallized PE have been calculated. A concept of "effective" jump motion has been proposed to explain the difference between the values derived from the chain diffusion coefficients and those in literatures. The observations of this thesis give a clear demonstration of the strong relationship between the sample morphology and chain dynamics. The sample morphologies governed by the processing history lead to different spatial constraints for the molecular chains, leading to different features of the local and long range chain dynamics. The knowledge of the morphological influence on the microscopic chain motion has many implications in our understanding of the alpha-relaxation process in PE and the related phenomena such as crystal thickening, drawability of PE, the easy creep of PE fiber, etc.

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I sistemi di versionamento moderni quali "git" o "svn" sono ad oggi basati su svariati algoritmi di analisi delle differenze (detti algoritmi di diffing) tra documenti (detti versioni). Uno degli algoritmi impiegati con maggior successo a tal proposito è il celebre "diff" di Unix. Tale programma è in grado di rilevare le modifiche necessarie da apportare ad un documento al fine di ottenerne un altro in termini di aggiunta o rimozione di linee di testo. L'insieme di tali modifiche prende nome di "delta". La crescente richiesta e applicazione dei documenti semi-strutturati (ed in particolar modo dei documenti XML) da parte della comunità informatica soprattutto in ambito web ha motivato la ricerca di algoritmi di diffing più raffinati che operino al meglio su tale tipologia di documenti. Svariate soluzioni di successo sono state discusse; algoritmi ad alte prestazioni capaci di individuare differenze più sottili della mera aggiunta o rimozione di testo quali il movimento di interi nodi, il loro riordinamento finanche il loro incapsulamento e così via. Tuttavia tali algoritmi mancano di versatilità. L'incapsulamento di un nodo potrebbe essere considerata una differenza troppo (o troppo poco) generale o granulare in taluni contesti. Nella realtà quotidiana ogni settore, pubblico o commerciale, interessato a rilevare differenze tra documenti ha interesse nell'individuarne sempre e soltanto un sottoinsieme molto specifico. Si pensi al parlamento italiano interessato all'analisi comparativa di documenti legislativi piuttosto che ad un ospedale interessato alla diagnostica relativa alla storia clinica di un paziente. Il presente elaborato di tesi dimostra come sia possibile sviluppare un algoritmo in grado di rilevare le differenze tra due documenti semi-strutturati (in termini del più breve numero di modifiche necessarie per trasformare l'uno nell'altro) che sia parametrizzato relativamente alle funzioni di trasformazione operanti su tali documenti. Vengono discusse le definizioni essenziali ed i principali risultati alla base della teoria delle differenze e viene dimostrato come assunzioni più blande inducano la non calcolabilità dell'algoritmo di diffing in questione.