893 resultados para Heroin Shortage


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On the aggravation of social problems and the shortage of resources, the improvement of evaluation methods and control of its application, requiring more efficiency, efficacy, effectiveness and participation in its management, has been growing. As a result, emerges the importance of studying and developing such methodologies. The overall goal of this dissertation is to know what are the difficults to incorporate the point of view of executers and beneficiaries in evaluation process. To do so, has been done a research characterized as qualitative, with a field strategy using the case study of two social projects called Petrobras Child Program, situated in the metropolitan region of Natal, and Content Analysis technique for analyze the data. The conclusions of this work can assist in improving the process of projects evaluation financed by Petrobras, contributing with its social role, besides the possibility of encouraging a greater participation of other society actors, such as beneficiaries, in the evaluation process

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Le contenu de ce mémoire traite du problème de gestion des stocks dans un réseau constitué de plusieurs sites de stockage de produits. Chaque site i gère son stock de manière autonome pour satisfaire une demande déterministe sur un horizon donné. Un stock maximum Si est tenu à chaque site i. Lorsque le point de commande si est atteint, une commande de taille Qi est placée au centre de distribution qui alimente tous les sites. Qi est telle que Qi = Si - si. La quantité Qi est livrée dans un délai connu Li. Si, à un instant donné, la demande Di au site i excède la quantité en main, le site i fait appel à un ou à plusieurs autres sites du réseau pour le transfert d’une quantité Xji (j = 1, 2, …, n). Ce transfert s’effectue selon un certain nombre de règles de jeu qui tiennent compte des coûts de transfert, de stockage, d’approvisionnement et de pénurie. Ce mémoire examine six principales contributions publiées dans la littérature pour évaluer les contributions d’un modèle collaboratif aux performances, en termes de coûts et de niveau de service, de chaque site du réseau. Cette investigation se limite à une configuration du réseau à deux échelons : un entrepôt central et n (n > 2) sites de stockage. Le cas des pièces de rechange, caractérisé par une demande aléatoire, est examiné dans trois chapitres de ce mémoire. Une autre application de ces stratégies à la collaboration entre n centres hospitaliers (n > 2) est également examinée dans ce travail.

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Se realizó un estudio descriptivo- retrospectivo desde enero de 2007 a diciembre del 2011. El universo estuvo constituido por los pacientes de 18 años y más con diagnóstico de Neumotórax, internados en los departamentos de cirugía del Hospital Regional Vicente Corral Moscoso y Hospital Teófilo Dávila. Para el levantamiento de la información se utilizó un formulario previamente diseñado. Los datos se transcribieron de las historias clínicas a los formularios respectivos. Resultados: Se incluyeron 73 pacientes del HTD y 52 del HVCM, el neumotórax de mayor prevalencia fue el traumático con el 85.6% de los casos, izquierdo en el 54.4%; las características clínicas de mayor relevancia fueron: dolor moderado 40.8%; taquicardia 15.2%; desviación de la tráquea hacia la derecha 32.8%; distención de las venas del cuello 38.4%; hipersonoridad 76.8%; murmullo vesicular disminuido 80%; disnea 99.2%; cianosis 22.4%; los método diagnósticos presentaron la siguiente prevalencia: radiografía de tórax 100%; tomografía 27.2% y resonancia en el 0.8% de los casos; el tratamiento fue en el 16% toracocentesis con aspiración de aguja y en el 100% tubo de tórax. La media de días de hospitalización fue de 5 días y la mortalidad fue del 10.4%.- Conclusiones: Se registraron diferencias estadísticamente significativas entre ambas instituciones en las características clínicas en cuanto a la procedencia, intensidad del dolor, frecuencia cardiaca, murmullo vesicular disminuido y presentación de cianosis. Además se evidencia una alta mortalidad.au

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Acompanha: Dupla-hélice: a construção de um conhecimento

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Selected papers from the 3rd Edition of the International Conference on Wastes: Solutions, Treatments and Opportunities

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Uno de los principales inconvenientes que tiene la pintura al óleo es su lento secado. Dicho esto, cabe preguntarse si existe algún tipo de pintura que tenga las cualidades de los óleos pero que sequen más rápido que estos. La respuesta, afirmativa, la encontramos en los óleos alquídicos, que en nuestro país únicamente se comercializan bajo la marca Griffin de Winsor & Newton. Se trata de unas pinturas relativamente recientes, poco conocidas por los pintores y muy poco estudiadas. Con el objetivo de paliar estas carencias, el presente artículo contiene las principales conclusiones de un trabajo en el que se ha estudiado la composición de las pinturas Griffin, sus principales características (viscosidad, brillo, flexibilidad, textura, opacidad, secado que es lo que más nos interesa, estabilidad etc.), su aplicación práctica mediante el arte pictórico (soportes, disolventes, reglas para pintar, correcciones, veladuras, barnizado, etc.) y su mezcla con otro tipo de procedimientos pictóricos como el óleo, el acrílico, la cera encáustica y diversos temples (huevo, cola y caseína).

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The eutrofization is a natural process of accumulation of nutrients in aquatic´s body that it has been accelerated for the human´s actives, mainly the related with the activities of camp, industrial and the inadequate disposition of the domestic sewage. The enrichment of the aquatic´s body with nutrients, mainly the nitrogen and the phosphorus, and the consequent proliferation of algae and Cyanobacteria can commit the quality of the water for the public provisioning, for the fish farming and for other ends. The problem becomes more critical when there is a shortage of water naturally as in the semi-arid area of the Brazilian northeast. Before that problem this work had as objective evaluates the trophic state of six reservoirs of the basin of River Seridó of Rio Grande of Norte and also estimate the capacity of load of match of the reservoir and risk probabilities based on the established limits by the resolution Conama 357/05. The results demonstrate that the six reservoirs are eutrofization, with concentration of total phosphorus and cloro a in the water upster to 50 e 12 μg l-1. The results show that space homogeneity exists in the state trophic of the reservoirs, but a significant variation interanual in function of the increase of the concentrations of nutrients and decrease of the transparency of the water with the reduction of the body of water accumulated in the reservoirs.The results of the simulation risk estocastic show that the reservoirs could receive annually from 72 to 216 Kg of P, assuming a risk of 10% of increasing in more than 30 μg l-1 the annual medium concentrations of total match in the water of these reservoirs. This load could be high in until 360 kg of P a year in case the managers assume a risk of 10% of increasing in more than 50 μg l-1 the annual medium concentrations of total phosphorus in the waters of these reservoirs

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This study examines the organizational structures and decision-making processes used by school districts to recruit and hire school librarians. For students to acquire the information and technology literacy education they need, school libraries must be staffed with qualified individuals who can fulfill the librarian’s role as leader, teacher, instructional partner, information specialist, and program administrator. Principals are typically given decision rights for hiring staff, including school librarians. Research shows that principals have limited knowledge of the skills and abilities of the school librarian or the specific needs and functions of the library program. Research also indicates that those with specific knowledge of school library programs, namely school district library supervisors, are only consulted on recruiting and hiring about half the time. School districts entrust library supervisors with responsibilities such as professional development of school librarians only after they are hired. This study uses a theoretical lens from research on IT governance, which focuses on the use of knowledge-fit in applying decision rights in an organization. This framework is appropriate because of its incorporation of a specialist with a specific knowledge set in determining the placement of input and decision rights in the decision-making processes. The method used in this research was a multiple-case study design using five school districts as cases, varying by the involvement of the supervisors and other individuals in the hiring process. The data collected from each school district were interviews about the district’s recruiting and hiring practices with principals, an individual in HR, library supervisors, and recently hired school librarians. Data analysis was conducted through iterative coding from themes in the research questions, with continuous adjustments as new themes developed. Results from the study indicate that governance framework is applicable to evaluating the decision-making processes used in recruiting and hiring school librarians. However, a district’s use of governance did not consistently use knowledge-fit in the determination of input and decision rights. In the hiring process, governance was more likely to be based on placing decision rights at a certain level of the district hierarchy rather than the location of specific knowledge, most often resulting in site-based governance for decision rights at the school-building level. The governance of the recruiting process was most affected by the shortage or surplus of candidates available to the district to fill positions. Districts struggling with a shortage of candidates typically placed governance for the decision-making process on recruiting at the district level, giving the library supervisor more opportunity for input and collaboration with human resources. In districts that use site-based governance and that place all input and decision rights at the building level, some principals use their autonomy to eliminate the school library position in the allotment phase or hire librarians that, while certified through testing, do not have the same level of expertise as those who achieve certification through LIS programs. The principals in districts who use site-based governance for decision rights but call on the library supervisor for advisement stated how valuable they found the supervisor’s expertise in evaluating candidates for hire. In no district was a principal or school required to involve the library supervisor in the hiring of school librarians. With a better understanding of the tasks involved, the effect of district governance on decision-making, and the use of knowledge to assign input and decision rights, it is possible to look at how all of these factors affect the outcome in the quality of the hire. A next step is to look at the hiring process that school librarians went through and connect those with the measurable outcomes of hiring: school librarian success, retention, and attrition; the quality of school library program services, outreach, and involvement in a school; and the perceptions of the success of the school librarian and the library program as seen from students, teachers, administrators, parents, and other community stakeholders.

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O crescimento da população mundial e a tentativa de substituição parcial dos combustíveis fósseis por novas fontes de energia têm levado a uma maior atenção quanto à possível escassez de alimentos e a carência de grandes áreas disponíveis para agricultura. Microalgas, por meio do metabolismo fotossintético, utilizam energia solar e gás carbônico como nutrientes para o crescimento. A microalga Spirulina pode ser utilizada como suplemento alimentar, na biofixação de CO2, como fonte de biocombustíveis e no tratamento de efluentes. A digestão anaeróbia da biomassa microalgal produz biogás e os resíduos deste processo podem ser utilizados como substrato para novos cultivos da microalga. O objetivo deste trabalho foi estudar a conversão de Spirulina sp. LEB-18 em biogás em escala piloto e produzir biomassa microalgal utilizando os efluentes bicarbonato e dióxido de carbono do processo anaeróbio como fonte de nutrientes. Spirulina foi utilizada como substrato na digestão anaeróbia para produção de biogás em escala piloto sob temperaturas variáveis (12- 38 °C). Efluente do processo anaeróbio foi adicionado (20 %, v/v) como fonte de carbono no cultivo da microalga para avaliar o crescimento e a composição da biomassa. A seguir foi avaliada a capacidade da microalga de remover CO2 presente no biogás através de biofixação para obtenção do biocombustível purificado. O biogás produzido sob as diferentes temperaturas apresentou entre 72,2 e 74,4 % de CH4, quando realizado nas temperaturas 12 a 21 °C e 26 a 38 °C, respectivamente. A redução na temperatura do processo anaeróbio provocou um decréscimo na conversão de biomassa em biogás (0,30 para 0,22 g.g-1 ), ocorrendo dentro da faixa adequada e segura para as bactérias metanogênicas (pH 6,9; alcalinidade entre 1706,0 e 2248,0 mg.L-1 CaCO3 e nitrogênio amoniacal 479,3 a 661,7 mg.L-1 ). Os cultivos de Spirulina sp. LEB-18 em efluente anaeróbio contendo 20 % (v/v) e meio Zarrouk modificado (NaHCO3 2,8 e 5,3 g.L-1 ) apresentaram velocidade específica máxima de crescimento entre 0,324 e 0,354 d-1 , produtividade volumétrica entre 0,280 e 0,297 g.L-1 .d-1 e produtividade areal entre 14,00 e 14,85 g.m-2 .d-1 , sem diferenças significativas (p > 0,05) entre as diferentes condições estudadas. Lipídios variaram entre 4,9 e 5,0 % com proporção de ácido linoleico maximizada nos meios com efluente e ácido alfa-linolênico reduzida nesses meios em comparação ao meio Zarrouk completo. Nos ensaios para avaliar a capacidade da microalga Spirulina sp. LEB-18 de remover CO2 contaminante no biogás, as máximas concentrações celulares e produtividades de biomassa variaram, respectivamente, entre 1,12 e 1,24 g.L-1 e 0,11 e 0,14 g.L-1 .d-1 , não apresentando diferenças significativas (p > 0,05) entre os ensaios. A maior fixação diária total (FDT) de dióxido de carbono obtida foi 58,01 % (v/v) em cultivos com adição de biogás contendo 25 % (v/v) CO2. Obteve-se biogás com 89,5 % (v/v) de CH4 após injeção em cultivos de Spirulina, no qual aproximadamente 45 % (v/v) do CO2 injetado foi fixado pela microalga, gerando biomassa para diversas aplicações e biogás purificado.

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Transplantation is one of the medical activities with more expectation of success. For patients with end stage renal disease, kidney transplantation provides a better quality of life compared with those on dialysis, even for those with advanced age or co-morbidities. Greater access to food since the Second World War, high exposure to chemical and toxic, associated with changes in lifestyles, increased diabetes, hypertension, obesity, cardiovascular disease, chronic renal failure and transplantation demands. The dream of replacing damaged parts in the human body materialized with the transplants, but the hope in transplantation reached much higher levels than the actual results deserve. The transplant was used as flags of technical and scientific differentiation and success. Nonetheless transplantation was faced with shortage of organs and increased demand. The claim to the right to treatment quickly was confused and understood as the right to transplantation.

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A emergência de questões tecnológicas, sociais e ambientais transformam o ensino das ciências num enorme desafio. A escassez e a contaminação da água, resultante de actividades antropogénicas, perspectiva-se hoje como um problema de futuro. Este tema, parte integrante do programa de Química do 11o Ano, inspirou uma intervenção didáctica baseada numa metodologia de resolução problemas que se pode enquadrar numa abordagem do tipo CTSA. A intervenção proposta, a partir de uma saída de campo que se concretizou na Mina de S. Domingos, teve por objectivos melhorar as aprendizagens realizadas pelos alunos e promover a mudança de atitudes face ao Ambiente e ao consumo de água em particular. Os dados recolhidos, analisados segundo métodos qualitativos e quantitativos, revelaram melhores conhecimentos e atitudes mais favoráveis relativamente à Ciência e à disciplina de Física e Química, e face ao Ambiente e ao consumo de água, reforçando a importância deste tipo de abordagens. ABSTRACT; The emergent technology, social and environmental issues are making the science teaching a huge challenge. The shortage and the contamination of water, as result of anthropogenic activities, are faced today like a future problem. This theme is part of the Chemistry subject curriculum of the eleventh grade level and it inspired a didactic intervention based upon a problem solving methodology that can be framed in a STSE approach. The goals of the proposed intervention, taking Mina de S. Domingos for a field trip, meant to improve the students' learnings and to promote a change of attitudes in relation to the environment and to the water consumption, in particular. The collected data, analyzed according to qualitative and quantitative methods, showed better knowledge and more favorable attitudes towards Science and Physics and Chemistry, as well as regarding the environment and water consumption, enhancing the importance of this kind of approach.

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This poetry collection explores the concepts of addiction and redemption. It does so through a series of vignette-style poems set in the Baltimore and DC area at the height of the heroin epidemic in the United States. Split into three parts, the first addresses the narrator’s initial drug use, the second follows the narrator at the strongest and least hopeful point of his addiction, and the third examines, through various scenes, the narrator’s attempts to find a life free from the confines of addiction. Although dealing with subject matter derived from dark and unfortunate circumstances, the narrator’s heroin addiction serves merely as a catalyst for the various situations that force the narrator to develop emotionally and grow even when trapped in the seemingly inescapable confines of addiction.

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Dissertação de Mestrado apresentada no Instituto Superior de Psicologia Aplicada para obtenção de grau de Mestre na especialidade de Psicologia Clínica

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Background: Body composition is affected by diseases, and affects responses to medical treatments, dosage of medicines, etc., while an abnormal body composition contributes to the causation of many chronic diseases. While we have reliable biochemical tests for certain nutritional parameters of body composition, such as iron or iodine status, and we have harnessed nuclear physics to estimate the body’s content of trace elements, the very basic quantification of body fat content and muscle mass remains highly problematic. Both body fat and muscle mass are vitally important, as they have opposing influences on chronic disease, but they have seldom been estimated as part of population health surveillance. Instead, most national surveys have merely reported BMI and waist, or sometimes the waist/hip ratio; these indices are convenient but do not have any specific biological meaning. Anthropometry offers a practical and inexpensive method for muscle and fat estimation in clinical and epidemiological settings; however, its use is imperfect due to many limitations, such as a shortage of reference data, misuse of terminology, unclear assumptions, and the absence of properly validated anthropometric equations. To date, anthropometric methods are not sensitive enough to detect muscle and fat loss. Aims: The aim of this thesis is to estimate Adipose/fat and muscle mass in health disease and during weight loss through; 1. evaluating and critiquing the literature, to identify the best-published prediction equations for adipose/fat and muscle mass estimation; 2. to derive and validate adipose tissue and muscle mass prediction equations; and 3.to evaluate the prediction equations along with anthropometric indices and the best equations retrieved from the literature in health, metabolic illness and during weight loss. Methods: a Systematic review using Cochrane Review method was used for reviewing muscle mass estimation papers that used MRI as the reference method. Fat mass estimation papers were critically reviewed. Mixed ethnic, age and body mass data that underwent whole body magnetic resonance imaging to quantify adipose tissue and muscle mass (dependent variable) and anthropometry (independent variable) were used in the derivation/validation analysis. Multiple regression and Bland-Altman plot were applied to evaluate the prediction equations. To determine how well the equations identify metabolic illness, English and Scottish health surveys were studied. Statistical analysis using multiple regression and binary logistic regression were applied to assess model fit and associations. Also, populations were divided into quintiles and relative risk was analysed. Finally, the prediction equations were evaluated by applying them to a pilot study of 10 subjects who underwent whole-body MRI, anthropometric measurements and muscle strength before and after weight loss to determine how well the equations identify adipose/fat mass and muscle mass change. Results: The estimation of fat mass has serious problems. Despite advances in technology and science, prediction equations for the estimation of fat mass depend on limited historical reference data and remain dependent upon assumptions that have not yet been properly validated for different population groups. Muscle mass does not have the same conceptual problems; however, its measurement is still problematic and reference data are scarce. The derivation and validation analysis in this thesis was satisfactory, compared to prediction equations in the literature they were similar or even better. Applying the prediction equations in metabolic illness and during weight loss presented an understanding on how well the equations identify metabolic illness showing significant associations with diabetes, hypertension, HbA1c and blood pressure. And moderate to high correlations with MRI-measured adipose tissue and muscle mass before and after weight loss. Conclusion: Adipose tissue mass and to an extent muscle mass can now be estimated for many purposes as population or groups means. However, these equations must not be used for assessing fatness and categorising individuals. Further exploration in different populations and health surveys would be valuable.

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Odpowiedzialność karną lekarza łączy się powszechnie z problematyką błędu medycznego, choć właściwie odpowiada on nie za sam błąd medyczny, jako że prawo karne nie zna przestępstwa polegającego na popełnieniu błędu medycznego, ale za ewentualne jego skutki, które mogą być kwalifikowane jako nieumyślne spowodowanie śmierci, nieumyślne spowodowanie ciężkiego, średniego albo lekkiego uszczerbku na zdrowiu bądź nieumyślne narażenie na niebezpieczeństwo utraty życia albo ciężkiego uszczerbku na zdrowiu. Nie można oczywiście wykluczyć wystąpienia sytuacji, w której lekarz swoim zachowaniem zrealizowałby znamiona typu umyślnego, jednakże na potrzeby niniejszej publikacji przyjęto, że co do zasady lekarz działa w celu ratowania dóbr prawnych, jakimi są życie i zdrowie pacjenta, nie zaś z zamiarem narażenia ich na niebezpieczeństwo bądź naruszenia, a ewentualne negatywne skutki dla życia i pacjenta, powstałe w miejsce lub obok zamierzonego stanu rzeczy, nie są przez niego objęte umyślnością. Kluczowym warunkiem uznania, że czyn popełniony został nieumyślnie jest ustalenie, że sprawca naruszył reguły ostrożnego postępowania, wymagane w danych okolicznościach. W odniesieniu do zawodu lekarza na pierwszy plan wysuwa się wśród nich wymóg stosowania się do wskazań aktualnej wiedzy medycznej. Autorka przekłada ten obowiązek na grunt realiów systemu ochrony zdrowia i rozważa, jaki wpływ na jego niedopełnienie mają okoliczności ograniczonej względami ekonomicznymi dostępności świadczeń zdrowotnych oraz w jaki sposób niedostatek środków finansowych może rzutować na naruszenie przez lekarza reguł ostrożnego postępowania, o których mowa w art. 9 § 2 Kodeksu karnego.