Grain size and heavy mineral analysis of Sander in Schleswig-Holstein, Germany

Die Sandergebiete sind von 5 Zentren her geschüttet, den Gletschertoren bei Flensburg, Frörup/Översee, Idstedt/Lürschau, Schleswig, Owschlag. Die Körnung der Schmelzwassersande nimmt mit zunehmender Entfernung von den Gletschertoren zunächst schnell, von Medianwerten über 1 mm auf Medianwerte um 0,4 mm in 10 km, dann langsam bis auf Medianwerte unter 0,2 mm in 30 km Entfernung ab. Sortierung und Symmetrie der Sande steigen entsprechend. Aus den Kornverteilungen lassen sich die Fließgeschwindigkeiten bei der Ablagerung ablesen. Sie sind geringer gewesen, als es die mächtigen und verbreiteten Akkumulationen erscheinen lassen. Bereits in 6 km Entfernung vom Eisrand flossen die Schmelzwässer als träge Bäche (0,3 m/sec) ab. In den Gletschertoren traten stoßweise extreme Fließgeschwindigkeiten auf, waren aber nur in geringem Maße am Gesamtaufbau der Sander beteiligt. Die Verbreitung der Würmsande paßt sich den Formen einer älteren Landschaft an. Sie läßt sich im behandelten Gebiet mit Hilfe der Schwermineralanalyse deutlich gegenüber den rißzeitlichen Ablagerungen abgrenzen, da die Verteilungen in den verschiedenaltrigen Sedimenten unterschiedlich sind. Vor Allem das Hornblende/Epidotverhältnis (Hornblendezahl nach STEINERT) ist ein gutes Kriterium. Da rißzeitliche Ablagerungen von den Schmelzwässern aufgearbeitet wurden, und zudem die Hornblenden im Laufe des Transportes stark abrollen, verwischen sich die Unterschiede in weiter Entfernung vom Eisrand. Schmelzwassersande der Würmvereisung sind vor Allem im Norden des Arbeitsgebietes weit nach Westen, bis an die nordfriesischen Inseln, geschüttet worden. Die Schmelzwässer benutzten als Durchlässe zu den Senken des Eemmeeres an der Westküste Täler in rißzeitlichen Hochgebieten. Die Wassermengen wurden hier gebündelt, sodaß sich auf den Eemablagerungen im Anschluß an die Durchlässe "Sekundärsander" ausbreiteten. Die Mächtigkeit der anstehenden Würm-Sandergebiete beträgt bis zu 20 m, meistens zwischen 10 und 15 m. An der Westküste sind die Schmelzwasserablagerungen von marinem Alluvium überdeckt. Teile der morphographisch als junge Sanderebenen erscheinenden Gebiete bestehen in Wirklichkeit aus rißzeitlichen, von jungen Schmelzwässern allenfalls oberflächlich umgearbeiteten Ablagerungen der älteren Vereisung. So ist der westliche und südwestliche Teil des Schleisanders schon während der Rißvereisung aufgeschüttet.

XRF measurements, CNS content, grain size and sediment accumulation of sediment core NC_08/01 from lake Nam Co, Tibet

Decadal to sub-decadal variability of inflow, evaporation and biological productivity derived from Lake Nam Co was used to reconstruct hydrological changes for the past ca. 24 k cal a BP. The timing of these variations corresponds to known climatic shifts on the Northern Hemisphere. After a dry and cold Last Glacial Maximum the lake level of Nam Co initially rose at ca. 20 k cal a BP. Moist but further cold conditions between ca. 16.2 and 14 k cal a BP correspond to Heinrich Event 1. A warm and moist phase between ca. 14 and 13 k cal a BP is expressed as a massive enhancement in inflow and biological productivity and might be associated with a first intensification of the Indian Ocean Summer Monsoon coinciding with the Bølling-Allerød complex. A twostep decrease in inflow and a contemporaneous decline in biological productivity until ca. 11.8 k cal a BP points to cool and dry conditions during the Younger Dryas. Lake levels peak at ca. 9.4 k cal a BP, although hydrological conditions remain relatively stable during the Holocene with only low-amplitude variations observed.

A monster that lives in our lives - experiences of caregivers of people with motor neuron disease and identifying avenues for support.

Background A developing body of evidence has provided valuable insight into the experiences of caregivers of people with motor neuron disease; however, understandings of how best to support caregivers remain limited.

Aim This study sought to understand concepts related to the motor neuron disease caregiver experience which could inform the development of supportive interventions.

Design A qualitative thematic analysis of a one-off semistructured interview with caregivers was undertaken.

Setting/participants Caregivers of people with motor neuron disease were recruited from a progressive neurological diseases clinic in Melbourne, Australia.

Results 15 caregivers participated. Three key themes were identified: (1) The Thief: the experience of loss and grief across varied facets of life; (2) The Labyrinth: finding ways to address ever changing challenges as the disease progressed; (3) Defying fate: being resilient and hopeful as caregivers tried to make the most of the time remaining.

Conclusions Caregivers are in need of more guidance and support to cope with experiences of loss and to adapt to changeable care giving duties associated with disease progression. Therapeutic interventions which target these experiences of loss and change are worth investigation.

Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance.

The progressive elucidation of the molecular pathogenesis of cancer has fueled the rational development of targeted drugs for patient populations stratified by genetic characteristics. Here we discuss general challenges relating to molecular diagnostics and describe predictive biomarkers for personalized cancer medicine. We also highlight resistance mechanisms for epidermal growth factor receptor (EGFR) kinase inhibitors in lung cancer. We envisage a future requiring the use of longitudinal genome sequencing and other omics technologies alongside combinatorial treatment to overcome cellular and molecular heterogeneity and prevent resistance caused by clonal evolution.

The Great Transition:Climate, disease and society in the late-medieval world

In the fourteenth century the Old World witnessed a series of profound and abrupt changes in the trajectory of long-established historical trends. Trans-continental networks of exchange fractured and an era of economic contraction and demographic decline dawned from which Latin Christendom would not begin to emerge until its voyages of discovery at the end of the fifteenth century. In a major new study of this 'Great Transition', assessment is made of the contributions of commercial recession, war, climate change,and eruption of the Black Death to a far-reaching reversal of fortunes which spared no part of Eurasia. A wealth of new historical, palaeoecological and biological evidence are synthesised, including estimates of national income, reconstructions of past climates. and genetic analysis of DNA extracted from the teeth of plague victims, to provide a fresh account of the creation, collapse and realignment of western Europe's late-medieval commercial economy.

Radiopacity and Chemical resistance of Elastomer-Barium sulphate nanocomposites

The Human race of our century is in gluttonous search for novel engineering products which led to a skyrocketed progress in research and fabrication of filled polymers. Recently, a big window has been opened up for speciality polymers especially elastomers with promising properties. Among the many reasons why rubbers are widely used in the process industries, three are considered as important. Firstly, rubbers operate in a variety of environments and possess usable ranges of deformity and durability and can be exploited through suitable and more or less conventional equipment design principles. Secondly, rubber is an eminently suitable construction material for protection against corrosion in the chemical plant and equipment against various corrosive chemicals as, acids and alkalies and if property tailored, can shield ionising radiations as X-rays and gamma rays in medical industry, with minimum maintenance lower down time, negligible corrosion and a preferred choice for aggressive corroding and ionising environment. Thirdly, rubber can readily and hastily, and at a relatively lower cost, be converted into serviceable products, having intricate shapes and dimensions. In a century’s gap, large employment of flexible polymer materials in the different segments of industry has stimulated the development of new materials with special properties, which paved its way to the synthesis of various nanoscale materials. At nano scale, one makes an entry into a world where multidisciplinary sciences meet and utilises the previously unapproached infinitesimal length scale, having dimension which measure upto one billionth of a meter, to create novel properties. The nano fillers augment the elastomers properties in an astonishing fashion due to their multifunctional nature and unprecedented properties have been exhibited by these polymer-nanocomposites just to beat the shortcomings of traditional micro composites. The current research aims to investigate the possibility of using synthesised nano barium sulphate for fabricating elastomer-based nanocomposites and thereby imparting several properties to the rubber. In this thesis, nano materials, their synthesis, structure, properties and applications are studied. The properties of barium sulphate like chemical resistance and radiopacity have been utilized in the present study and is imparted to the elastomers by preparing composites.

Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study

[EN]It is unknown whether individuals at high cardiovascular risk sustain a benefit in cardiovascular disease from increased olive oil consumption. The aim was to assess the association between total olive oil intake, its varieties (extra virgin and common olive oil) and the risk of cardiovascular disease and mortality in a Mediterranean population at high cardiovascular risk

Phosphate Deficiency Induces the Jasmonate Pathway and Enhances Resistance to Insect Herbivory.

During their life cycle, plants are typically confronted by simultaneous biotic and abiotic stresses. Low inorganic phosphate (Pi) is one of the most common nutrient deficiencies limiting plant growth in natural and agricultural ecosystems, while insect herbivory accounts for major losses in plant productivity and impacts ecological and evolutionary changes in plant populations. Here, we report that plants experiencing Pi deficiency induce the jasmonic acid (JA) pathway and enhance their defense against insect herbivory. Pi-deficient Arabidopsis (Arabidopsis thaliana) showed enhanced synthesis of JA and the bioactive conjugate JA-isoleucine, as well as activation of the JA signaling pathway, in both shoots and roots of wild-type plants and in shoots of the Pi-deficient mutant pho1 The kinetics of the induction of the JA signaling pathway by Pi deficiency was influenced by PHOSPHATE STARVATION RESPONSE1, the main transcription factor regulating the expression of Pi starvation-induced genes. Phenotypes of the pho1 mutant typically associated with Pi deficiency, such as high shoot anthocyanin levels and poor shoot growth, were significantly attenuated by blocking the JA biosynthesis or signaling pathway. Wounded pho1 leaves hyperaccumulated JA/JA-isoleucine in comparison with the wild type. The pho1 mutant also showed an increased resistance against the generalist herbivore Spodoptera littoralis that was attenuated in JA biosynthesis and signaling mutants. Pi deficiency also triggered increased resistance to S. littoralis in wild-type Arabidopsis as well as tomato (Solanum lycopersicum) and Nicotiana benthamiana, revealing that the link between Pi deficiency and enhanced herbivory resistance is conserved in a diversity of plants, including crops.

The Iowa Grain Flow Survey: Where and How Iowa Grain Producers and Country Elevators Shipped Corn and Soybeans During September 1, 1999 - August 31, 2000, 2001

In September 1996, a grain flow survey consisting of two parts was completed and published. One part was a farm-to-market survey from a sample of Iowa grain producers, and the second was a survey of all Iowa country elevators. An updated survey for the crop year September 1, 1999 -August 31, 2000, was initiated in September 2000. The results of the two updated surveys are presented in this report. The purpose of the surveys is to estimate the amount of Iowa corn and soybeans that are shipped from each crop reporting district to each major market. Copies of the two questionnaires are presented in the appendices.

Tooth Mobility, Periodontal Ligament Space, and the Alveolus During Periodontal Health, Disease, and Disuse

Thesis (Ph.D.)--University of Washington, 2016-07

Improving DPA and DFA resistance of circuits using asynchronous logic

International audience