961 resultados para Constructive Alignment
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Dissertação de mestrado integrado em Arquitectura
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Alzheimer's disease (AD) is commonly associated with marked memory deficits; however, nonamnestic variants have been consistently described as well. Posterior cortical atrophy (PCA) is a progressive degenerative condition in which posterior regions of the brain are predominantly affected, therefore resulting in a pattern of distinctive and marked visuospatial symptoms, such as apraxia, alexia, and spatial neglect. Despite the growing number of studies on cognitive and neural bases of the visual variant of AD, intervention studies remain relatively sparse. Current pharmacological treatments offer modest efficacy. Also, there is a scarcity of complementary nonpharmacological interventions with only two previous studies of PCA. Here we describe a highly educated 57-year-old patient diagnosed with a visual variant of AD who participated in a cognitive intervention program (comprising reality orientation, cognitive stimulation, and cognitive training exercises). Neuropsychological assessment was performed across moments (baseline, postintervention, follow-up) and consisted mainly of verbal and visual memory. Baseline neuropsychological assessment showed deficits in perceptive and visual-constructive abilities, learning and memory, and temporal orientation. After neuropsychological rehabilitation, we observed small improvements in the patient's cognitive functioning, namely in verbal memory, attention, and psychomotor abilities. This study shows evidence of small beneficial effects of cognitive intervention in PCA and is the first report of this approach with a highly educated patient in a moderate stage of the disease. Controlled studies are needed to assess the potential efficacy of cognition-focused approaches in these patients, and, if relevant, to grant their availability as a complementary therapy to pharmacological treatment and visual aids.
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O estudo da análise das políticas de Acesso Aberto registadas no ROARMAP: “Working together to promote Open Access policy alignment in Europe” procurou descrever o panorama mundial e Europeu das políticas de Acesso Aberto existentes, assim como analisar a sua e ficácia.
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Dissertação de mestrado integrado em Engenharia e Gestão de Sistemas de Informação
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Dissertação de mestrado integrado em Engenharia Biomédica (área de especialização em Engenharia Clínica)
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Dissertação de mestrado integrado em Engenharia e Gestão de Sistemas de Informação
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Enzymatic polymerization of aniline was first performed in lignosulfonate (LGS) template system. High-redox-potential catalyst laccase, isolated from Aspergillus, was used as a biocatalyst in the synthesis of conducting polyaniline/lignosulfonate (PANI-ES-LGS) complex using atmospheric oxygen as the oxidizing agent. The linear templates (LGS), also serving as the dopants, could facilitate the directional alignment of the monomer and improve the solubility of the conducting polymer. The process of the polymerization was monitored using UV-Vis spectroscopy, by which the conditions for laccase-catalyzed synthesis of PANI-ES-LGS complex were also optimized. The structure characterizations and solubility of the complex were carried out using corresponding characterization techniques respectively. The PANI-ES-LGS suspensions obtained was used as coating for cotton with a conventional padder to explore the applications of the complex. The variable optoelectronic properties of the coated cotton were confirmed by cyclic voltammetry and color strength test. The molecular weight changes of LGS treated by laccase were also studied to discuss the mechanism of laccase catalyzed aniline polymerization in LGS template system.
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Doctoral Programme in Telecommunication - MAP-tele
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Tese de Doutoramento em Engenharia Civil
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Tese de Doutoramento em Ciências da Educação (área de especilização em Desenvolvimento Curricular).
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Dissertação de mestrado em Sustentabilidade do Ambiente Construído
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Dissertação de mestrado Internacional em Sustentabilidade do Ambiente Construído
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Dissertação de mestrado Internacional em Sustentabilidade do Ambiente Construído
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Dissertação de mestrado integrado em Engenharia Civil
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Dissertação de mestrado integrado em Engenharia Civil