602 resultados para Sulfadiazina de prata


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Dissertação apresentada à Escola Superior de Educação do Instituto Politécnico de Castelo Branco para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Supervisão e Avaliação Escolar.

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Since the classic era that monsters have been both the subject of worship and fear. Greeks used to valorize them making up new races which lived in faraway lands, in the East. There were traveler’s reports made up, from a moralist and religious point of view, always with veracity in mind, where anatomical weird beings were described. Saint Augustin tried to prove their existence, classifying them as wonders and focusing on stopping the idea of the corruption of the human soul by denying their relation between monstrous births and divine punishment. Monsters present then two distinct aspects when it comes to their origins: one that pushes back to monstrous births, seen as omens, and other that points to the existence of fantastic races in faraway places. However when it comes to structure these fantastic beings display finite compositions, not looking too different from each other. With the passage of time, besides their fearful role, monsters were being observed as scientific curiosities and at last, as recreation subjects, first in freak shows, now in several industries, being the most well know the cinematographic industry and the videogames one. Two creatures from the world known videogame World of Warcraft from Blizzard Entertainment were selected to be analyzed from a scientific point of view, were based on their features, there will be a comparative analysis with diverse anomalies and diseases (prognathism, acromegaly, cyclopia) existent , as well as comparative anatomy with other animals

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Enquadramento: A dor do parto resulta de complexas interações, de caráter inibitório e excitatório e, apesar de os seus mecanismos serem análogos aos da dor aguda, há fatores próprios do trabalho de parto de natureza neurofisiológica, obstétrica, psicológica e sociológica que intervêm no seu limiar. Neste sentido, os métodos não farmacológicas podem auxiliar a parturiente no alívio da dor, reduzir os níveis de stresse e ansiedade e, consequentemente promover uma maior satisfação. Objetivos: Demonstrar evidência científica de se os métodos não farmacológicos usados no alívio da dor no trabalho de parto são mais eficazes quando comparados com a não utilização de nenhum método, placebo ou qualquer outro método; verificar o uso de medidas não farmacológicas no alívio da dor do parto; averiguar quais as variáveis sociodemográficas, variáveis contextuais da gravidez e contextuais do parto que interferem no recurso a medidas não farmacológicas no alívio da dor do parto. Métodos: No estudo empírico I seguiu-se a metodologia de revisão sistemática da literatura. Foi realizada uma pesquisa na EBSCO, PubMed, Scielo e RCAAP, de estudos publicados entre 1 janeiro de 2010 e 2 de janeiro de 2015. Os estudos encontrados foram avaliados de acordo com os critérios de inclusão previamente estabelecidos e, posteriormente, foi feita uma apreciação da qualidade dos estudos, por dois revisores, utilizando a “Grelha para avaliação crítica de um artigo descrevendo um ensaio clínico prospetivo, aleatorizado e controlado” (Bugalho & Carneiro, 2004). No final, foram incluídos no corpus do estudo 4 artigos. O estudo empírico II enquadra-se num estudo quantitativo, transversal, descritivo e retrospetivo, desenvolvido no serviço de Obstetrícia do Centro Hospitalar Cova da Beira, segundo um processo de amostragem não probabilística por conveniência (n = 382). A recolha de dados efetuou-se através da consulta de processos clínicos de mulheres com idade ≥ 18 anos, que tiveram um parto vaginal com feto vivo após as 37 semanas de gestação. Resultados: Os métodos não farmacológicos usados no alívio da dor no trabalho de parto são mais eficazes quando comparados com a não utilização de nenhum método, placebo ou qualquer outro método. Numa amostra constituída por 382 mulheres, com uma idade média de 30,95 anos (±5,451 anos), em 34,6% dos casos foram aplicadas as medidas não farmacológicas no alívio da dor no trabalho de parto, sobressaindo a respiração e o relaxamento (86,3%). Em alguns casos, ainda que em menor número, foi aplicada a hidroterapia isolada (6,9%) ou associada à respiração e ao relaxamento (5,3%), bem como a hipnose (0,8%) e a associação entre respiração e massagem (0,8%). Conclusão: De acordo com os resultados obtidos e com base na evidência científica disponível, importa referir que é essencial que os cuidados não farmacológicos de alívio da dor no parto sejam explorados, por serem mais seguros e acarretarem menos intervenções. Desta feita, os profissionais de saúde que prestam assistência às mulheres durante o trabalho de parto e parto têm de ter acesso ao conhecimento acerca desses métodos e os seus potenciais benefícios, a fim de os poderem aplicar com maior segurança, o que resultará indiscutivelmente numa maior humanização do parto, caminhando-se no sentido de uma maternidade mais segura. Palavras-chave: Trabalho de parto; dor de parto; terapias complementares; terapias alternativas

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-T. III. Navegação nos mares Indicos, com as derrotas com monção, e pelos estreitos de E. 1844. -[pte. VII not published.] -pte. VIII. Costas do Pacifico dom ilhas adjacentes e derrotas. 1846. -[pte. IX not published.] -pte. X. t. I. Costas da America septentrional desde cabo Carlos até cabo Florida e de volta á embocadura do Mississippi no golfo do Mexico. 1842. t. II. Golfo do Mexico e costa da America, desde o rio Mississippi até Cabo Norte, com as ilhas Lacayas e Antilhas. 1846. -pte. XI. Costas do Brasil, de Cabo Norte até ao rio de Prata, com a Patagonia, Chili, e peru até ao isthmo de Panamá, com as ilhas adjcentes. 1839.

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In the context of climate change over South America (SA) has been observed that the combination of high temperatures and rain more temperatures less rainfall, cause different impacts such as extreme precipitation events, favorable conditions for fires and droughts. As a result, these regions face growing threat of water shortage, local or generalized. Thus, the water availability in Brazil depends largely on the weather and its variations in different time scales. In this sense, the main objective of this research is to study the moisture budget through regional climate models (RCM) from Project Regional Climate Change Assessments for La Plata Basin (CLARIS-LPB) and combine these RCM through two statistical techniques in an attempt to improve prediction on three areas of AS: Amazon (AMZ), Northeast Brazil (NEB) and the Plata Basin (LPB) in past climates (1961-1990) and future (2071-2100). The moisture transport on AS was investigated through the moisture fluxes vertically integrated. The main results showed that the average fluxes of water vapor in the tropics (AMZ and NEB) are higher across the eastern and northern edges, thus indicating that the contributions of the trade winds of the North Atlantic and South are equally important for the entry moisture during the months of JJA and DJF. This configuration was observed in all the models and climates. In comparison climates, it was found that the convergence of the flow of moisture in the past weather was smaller in the future in various regions and seasons. Similarly, the majority of the SPC simulates the future climate, reduced precipitation in tropical regions (AMZ and NEB), and an increase in the LPB region. The second phase of this research was to carry out combination of RCM in more accurately predict precipitation, through the multiple regression techniques for components Main (C.RPC) and convex combination (C.EQM), and then analyze and compare combinations of RCM (ensemble). The results indicated that the combination was better in RPC represent precipitation observed in both climates. Since, in addition to showing values be close to those observed, the technique obtained coefficient of correlation of moderate to strong magnitude in almost every month in different climates and regions, also lower dispersion of data (RMSE). A significant advantage of the combination of methods was the ability to capture extreme events (outliers) for the study regions. In general, it was observed that the wet C.EQM captures more extreme, while C.RPC can capture more extreme dry climates and in the three regions studied.

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Magnetic multilayers are the support for the production of spintronic devices, representing great possibilities for miniaturized electronics industry. having the control to produce devices as well as their physical properties from simple multilayer films to highly complex at the atomic scale is a fundamental need for progress in this area, in recent years has highlighted the production of organic and flexible spintronic devices. Because of this trend, the objective of this work was to produce magnetic multilayers deposited on flexible substrate using magnetron sputtering dc technique. Three sets of samples were prepared. The first set composed of the trilayer type CoFe=Cu(t)=CoFe with different thickness of the metallic spacer. The second set consists of two multilayer subgroups, CoFe=Cu in the presence of IrMn layer as a buffer and the next multilayer as cap layer. The third set consisting of non-magnetostrictive multilayer permalloy (Py=Ta and Py=Ag) on flexible substrate and glass. The magnetic properties, were investigated by magnetometry measurements, ferromagnetic resonance and magnetoimpedance (MI), measurements were carried out at room temperature with the magnetic field always applied on the sample plane. For structural analysis, the diffraction X-ray was used. The results of the trilayer showed a high uniaxial anisotropy field for the sample with a spacer of 4.2 nm. For the multilayer in the presence of IrMn layer as the buffer, the study of static and dynamic magnetic properties showed isotropic behavior. For the multilayer in the presence of IrMn layer as a cap, the results of static magnetic properties of the magnetic behavior exhibited a spin valve structure type. However there was a disagreement with results of ferromagnetic resonance measurements, which was justified by the contribution of the unstable and stable grain to the rotatable anisotropy and Exchange bias in ferromagneticantiferromagnetic interface. The third serie of samples showed similar results behavior for the MI Ag multilayers spacer in both substrates. There are also significant MI changes with the Ta spacer, possible associated with the compressive stress on the flexible substrate sample.

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This thesis addresses two spectacles: “Moleque tão Grande Otelo” and “Água Suja”, in which both have had my participation as producer and actress. The spectacle “Moleque tão Grande Otelo” reveals the racial-ethnic questions that surrounds the play and permeates the artist’s life whose name is the same. The play deals how the actor Grande Otelo life events’ had implied in his art, the facts that marked his career and they are shown at the spectacle, the reason why to articulate: art, life, fantasy and reality. Aiming to unveil the actor, I refer it to my history as an actress and the roots’ similarity to Sebastião Bernardes de Souza Prata, who became Grande Otelo to the world. In the staging of “Água Suja”, we also expose familial and religious memories and experiences of a people that overflow faith in a real spectacle, which takes place every year, in August, in our region, more specifically in Romaria – MG. While creating “Água Suja”, we experienced the act of keeping a promise and believing in the saint’s miracle, thus this experience is told in the spectacle and investigated in this study.

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The classical treatment for congenital toxoplasmosis is based on combination of sulfadiazine and pyrimethamine plus folinic acid. Due to teratogenic effects and bone marrow suppression caused by pyrimethamine, the establishment of new therapeutic targets is indispensable to minimize the undesirable effects and improve the control of the infection. Previous studies demonstrated that enrofloxacin and toltrazuril were able to control the infection triggered by Neospora caninum and Toxoplasma gondii. Therefore, the aim of this present study was evaluate the efficacy of enrofloxacin and toltrazuril in the control of T. gondii proliferation in human trophoblast cells (BeWo lineage) and in human villous explants from third trimester. BeWo cells and villous were treated with several concentrations of enrofloxacin, toltrazuril, sulfadiazine, pyrimethamine or association (sulfadiazine + pyrimethamine) in other to verify their viability by MTT or LDH assay, respectively. Next, BeWo cells were infected with T. gondii RH (2F1 clone) or ME49 strain, whereas villous were infected only with RH strain (2F1 clone), after, both cells and villous were treated or not with the same antibiotics and analyzed to T. gondii intracellular proliferation by beta-galactosidase assay (for RH strain) or blue toluidine staining (for ME49 strain). ELISA was performed in the supernatant to evaluate the cytokine profile. Enrofloxacin and toltrazuril did not change strongly the viability in cells and villous. Furthermore, the drugs decreased the parasite intracellular proliferation regardless T. gondii strain in BeWo cells and villous explants when compared to untreated and infected conditions. In BeWo cells infected by RH, enrofloxacin induced high levels of IL-6 low levels of MIF, while both cytokines were upregulated by enrofloxacin and toltrazuril in BeWo cells infected by ME49 strain. Additionally, in villous explantes, enrofloxacin induced high MIF production. Thus, enrofloxacin and toltrazuril were able to control the parasitism in BeWo cells and villous explants, and probably it occurs by modulation of immune response in these cells or tissues and direct action on parasite, but future experiments are necessary to verify this hypothesis.

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A versão impressa está dividida em volume 1 e 2.

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A public organization has a section for customer service which is responsible of order entry from customers concerning errands within real estate and business equipment, cleaning, transport operations and handicap appliance. According to the co-ordinators in hospitals within the organisation the customers are requesting for staff to talk to physically, meaning a person to speak with face to face. The customers experiencing that it’s sometimes difficult to call customer service or use the web form, which is the only communication paths in the current situation. Proposed changes presented claim that a complement to customer service with local service centers in every hospital. The purpose of this study is to evaluate a change proposition by weigh between efficiency and working environment, this by using multi-criteria analysis. To achieve the goal a decision model is designed in the decision tool DecideIT. The aim of the study is to recommend decision makers to choose one of the options based on as rational grounds as possible. The result of the study showed that the preferred alternative is not to supplement customer service with local service centers. For the most part, the result depending on the survey (represented result from working environment criteria) which showed that the majority of customers do not request a person to speak with face to face at all.

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Utomhuspedagogik har under de senaste åren ökat inom skolans värld. Jag har upplevt att lärare har börjat prata mer om utomhuspedagogik och använder det mer och mer i undervisningen. Mitt självständiga arbete handlar om hur lärare i grundskolan förskoleklass-åk3 använder sig av utomhusmatematik och i vilket syfte lärarna har när de undervisar inom utomhusmatematik. Studiens syfte är att undersöka i vilket syfte lärare använder utomhusmatematik, vilka positiva respektive negativa sidor de ser/upplever när de undervisar med undervisningsformen samt ett ungefärligt snittvärde på hur många timmar i veckan lärarna använder det. Metoden som tillämpas till denna studie är kvalitativa semistrukturerade intervjuer med fyra verksamma lärare på olika skolor i samma kommun. Resultatet visar att alla lärare jag intervjuade jobbade med utomhusmatematik varje vecka och var positiv till att jobba med det. Lärarna såg också att fler elever fångades upp när de valde att ta ut klassrummet och jobba mer praktiskt. Genom att jobba på detta sätt har alla elever en större chans att jobba mot sina mål samt att eleverna får använda sin lärstil eftersom många olika lärstilar blir möjliga att använda utomhus.

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Studier visar att svenska elevers resultat i matematik har försämrats och att en av de bakomliggande orsakerna till resultatnedgången är bristande begreppsförståelse. Samtidigt rapporteras det om att eleverna i undervisningen allt mer lämnas ensamma i sitt lärande i så kallat individuellt arbete. Tolkningen som kan göras är att det finns ett samband mellan elevers försämrade matematikkunskaper och undervisningen de möter i matematik. Syftet med denna studie är att få kunskap om hur matematikundervisningen kan utformas för att ge elever i årskurs 1-3 möjlighet att utveckla en god begreppsförståelse i matematik. Svaret söktes genom en systematisk litteraturstudie där litteratur och aktuell forskning söktes systematiskt. I studiens resultat exemplifieras en rad kommunikationsverktyg för läraren att använda direkt i undervisning, men också andra typer av verktyg, för att stödja och utveckla elevers förståelse för matematiska begrepp. Vidare synliggörs också fördelar med en lärare som möjliggör en undervisning där eleverna själva får kommunicera matematik och som agerar resurs för dem i deras övergång från det vardagliga till det matematiska språket. Kommunikation kan därför ses som ett viktigt verktyg i matematikundervisningen då det kommer till att utveckla elevers begreppsförståelse. Undervisningsmiljön behöver därför utformas till att passa en mer kommunikativ undervisning; en tillåtande miljö där eleverna tillåts och stöttas i att prata matematik.

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Studier visar att svenska elevers resultat i matematik har försämrats och att en av de bakomliggande orsakerna till resultatnedgången är bristande begreppsförståelse. Samtidigt rapporteras det om att eleverna i undervisningen allt mer lämnas ensamma i sitt lärande i så kallat individuellt arbete. Tolkningen som kan göras är att det finns ett samband mellan elevers försämrade matematikkunskaper och undervisningen de möter i matematik. Syftet med denna studie är att få kunskap om hur matematikundervisningen kan utformas för att ge elever i årskurs 1-3 möjlighet att utveckla en god begreppsförståelse i matematik. Svaret söktes genom en systematisk litteraturstudie där litteratur och aktuell forskning söktes systematiskt. I studiens resultat exemplifieras en rad kommunikationsverktyg för läraren att använda direkt i undervisning, men också andra typer av verktyg, för att stödja och utveckla elevers förståelse för matematiska begrepp. Vidare synliggörs också fördelar med en lärare som möjliggör en undervisning där eleverna själva får kommunicera matematik och som agerar resurs för dem i deras övergång från det vardagliga till det matematiska språket. Kommunikation kan därför ses som ett viktigt verktyg i matematikundervisningen då det kommer till att utveckla elevers begreppsförståelse. Undervisningsmiljön behöver därför utformas till att passa en mer kommunikativ undervisning; en tillåtande miljö där eleverna tillåts och stöttas i att prata matematik.

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Companies have always been organized by processes, often imperceptible to its employees. With the advancement of technology, organizational processes currently run an organization through computers, and thus generate immediate information that is available to each sector. With the objective of seeking business information in real time, the government created the SPED - Public System of Digital, which involves three subsystems, which are the Electronic Invoice, Digital Accounting Bookkeeping and Digital Tax Bookkeeping. This system is revolutionizing the business structures when gathering, in an innovative way, all information and interlinked business processes. For the implementation of SPED, a revision in the organizational processes is required, since the information is generated and is sent online to the government, without mistakes. Thus the study aimed to analyze the change brought about by the implementation of the Public System of Digital SPED in the main business processes. In order to do so, we have performed a multiple case study involving three companies in the state of Para, two operate in wholesale and one explores agribusiness. The Data collection was performed by accounting professionals, IT and managers. According to the results obtained, it was found that in two companies, the IT infrastructure was capable of deploying the new system without major problems, while one company had more difficulties to cope with the new system. However, all companies had to examine its processes to make the customizations needed to fit. It was also observed that there is no IT Governance in two companies. Therefore, we recommend the use of an appropriate model, not only for the implementation of SPED, but as a way to manage and extract better results from investment in information technology

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Syftet med denna uppsats var att genom ett salutogent perspektiv få en ökad förståelse för, inom äldreomsorgen verksamma, biståndshandläggares arbetssituation samt att undersöka vad som kan bidra till att biståndshandläggares arbetssituation upplevs som lättare och mindre påfrestande. Metoden som använts är kvalitativa intervjuer där sex biståndshandläggare verksamma i Värmland har intervjuats. Intervjuerna analyserades genom teman ur KASAM och resulterade i kategorier under varje tema. Under temat begriplighet framkom att biståndshandläggare får stöd från sina kollegor men att de också önskar att det fanns mer resurser för handledning. Biståndshandläggare utför mer än vad som ingår i arbetsbeskrivningen. Under temat hanterbarhet framgår att hög arbetsbelastning hanteras genom att biståndshandläggarna måste planera, strukturera och prioritera. Kollegornas stöd gör arbetet lättare att hantera då de genom att prata med varandra bearbetar känslomässigt påfrestande delar av arbetet. De uttryckte olika behov av att reflektera över sitt arbete. Biståndshandläggare har en stor frihet att planera sin egen arbetsdag och de samverkar med andra professioner. Under temat meningsfullhet framgår att biståndshandläggare finner mening i att göra skillnad för den enskilde. Vårt resultat visar att biståndshandläggarna är utsatta för stress i sitt arbete och att de också har förmåga att möta stressen, men förmågan att möta stressen minskar när arbetsbelastningen blir för hög.