999 resultados para Interações entre pares
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O estudo propõe uma reflexão teórica sobre a produção de imagens na era do espetáculo e sua relação com a comunicação. A sistematização da pesquisa bibliográfica sobre a teoria da Sociedade do Espetáculo em Guy Debord leva em conta as questões que decorrem do excesso de luz na produção de imagens, tratada por esta pesquisa por meio do termo luzes da comunicação e apontada como uma das bases da incomunicação. O trabalho pontua a evolução das teorias da comunicação em uma releitura da noção de Sociedade do Espetáculo à luz das novas interações midiáticas. A pesquisa explora as relações sociais e a imagem na dimensão do imaginário e estuda o mito no contexto comunicacional. O esforço da pesquisa trata o mito do espetáculo como o inverso do mito da caverna de Platão onde a caverna seria o próprio espetáculo, lugar das muitas luzes, lugar da incomunicabilidade. A reflexão se depara com novos desafios no mapeamento teórico e na análise dessas novas formas de cultura do espetáculo e de sociedade e de como elas podem conter outras formas de poder nessa relação entre comunicação e suas conexões midiáticas. Por fim, a pesquisa trabalha a possibilidade da prática de alteridade nas relações humanas pela luz da comunicação.
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Este estudo tem como objetivo analisar como os processos comunicacionais de manifestações perceptivas dos consumidores pós-modernos, a partir das interações em redes sociais virtuais, contribuem para a ressignificação da imagem de marca. Reavaliamos o processo comunicacional ante as novas interações econômicas e tecno-sociais, partindo de uma visão de consumo de significados e um deslocamento do marketing das necessidades para um marketing de sentidos. Para tanto, desenvolvemos um estudo de caso único da marca Lego, a partir de levantamento bibliográfico, levantamentos qualitativos das interações em sites, análise de conteúdo de blog e análise qualitativa de fórum de consumidores da marca. Assim, concluímos que a comunicação de mercado assume um papel aglutinador nas construções simbólicas da imagem de marca nas organizações e que a facilidade econômica e atemporal em compartilhar manifestações por meio da internet ressignifica a imagem de marca em um papel de troca simbólica na bolsa de valores de imagens das redes on-line.
ERVING GOFFMAN, AS INTERAÇÕES NO COTIDIANO ESCOLAR, DESVENDANDO O ESTIGMA DENTRO DA INCLUSÃO ESCOLAR
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As pessoas com deficiências são excluídas da sociedade devido à marca negativa de descrédito recebida pelo meio social - por sua aparência ou seu modo de ser diferentes - que os coloca fora da norma classificando-os como seres desviantes. No cotidiano escolar essas marcas se afirmam e se reproduzem, não promovendo às pessoas com deficiências uma superação desse estigma. A pesquisa visa analisar como o estigma incorporado pelos alunos com deficiências influencia no processo de interação e inclusão escolar, de forma a estudar indícios de como se desenvolve o processo de estigmatização no cotidiano escolar sob a luz dos pensamentos de Erving Goffman. O presente estudo utiliza-se uma revisão de literatura especifica do tema, fundamentada nos estudos de Erving Goffman, conjuntamente à pesquisa empírica baseada na etnografia vivenciada pelo autor em seus estudos de comunidade, foram utilizadas como estratégias de pesquisa, entrevistas com três professores e observações registradas por meio de de observação de cenas do cotidiano escolar de ´duas escolas públicas do estado de SPSão Paulo . No capítulo 1 buscamos entender os constructos de Goffman principalmente por meio de sua trajetória acadêmica, no capítulo 2 o trabalho centrou-se na compreensão da interação social e principalmente na questão definida pelo autor como ordem da interação, em queentende-se que as pessoas são autores dentro de um palco social, no capítulo 3. a pesquisa aborda o termo estigma e explica sua influência na interação e no avanço das pessoas com deficiência. Por fim, o trabalho se encerra no capítulo .4 apresentando a análise das entrevistas e dos registros das cenas do cotidiano escolar. As cenas selecionadas apresentam os atores envolvidos, o cenário, e o enredo das interações, identificando as estratégias do estigma incorporado pelos alunos com deficiência e buscando ligações com as políticas inclusivas e as escolas brasileira. A pesquisa identificou que a escola, como meio de socialização e criação de saberes, possui um papel importante neste processo de mudança, apesar de muitas vezes reproduzir o estigma social. Observamos então que a escola pode auxiliar na mudança do olhar que exclui, à maneira que mostra algumas máscaras do social e da própria inclusão; no entanto é importante salientar que sua renovação e de seus agentes sociais deve valorizar as diferenças para construção de novos conhecimentos.(AU)
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This paper focalizes the initial teacher socialization in the Infantile Education from the acknowledgement about that as a phase of a professional life cycle on distinguish of other steps in the teachers’ carrier. It is based on the studies of sociological and anthropological mark with the comprehension that the professional reality is equally constructed by daily practices of social interactions in the work environment. It aims understanding how the initial process of professional culture building of beginners in the infantile education occurs under a view toward to the organizational and dynamics aspects of the teacher activity (events, interactions, practices, wisdoms, tensions and dilemmas). This investigation assuming the orientations of an ethnographic type approach has been developed in a Municipal Center of Infantile Education (Centro Municipal de Educação Infantil) in the city of Natal, with daycare and pre-school. The participant subjects are four female teachers with less than five years in Infantile Education career. It has used a participant observation and a semi-structured interview in the data building that had interpreted through a content analysis and sources triangulation. It delineates three dimensions to the professional culture scenarios: the personal and formative profile of the subjects, the school daily and the teacher work management. The multiform character of the finds evidences that the professional culture of the novice teachers has been constituted from the confrontation with different situations of unpredictably in their emotions, routines and pedagogical and administrative difficulties, simultaneously to the dilemmas of child care and educate. The solitude feeling has been generating from the institutional and scholar organization, which offers no material and pedagogical conditions to the peers collaboration and discussion. Finally it means that teaching in the Infantile Education must been based on an expanding network relations, been indispensable to the beginners the support and orientation related to doubts, wistfulness and expectations as means of socializing and redefining their teaching practice
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Dengue virus is an important patogen that causes Dengue desease in all world, and belongs to Flavivirus gender. The virus consists of enveloped RNA with a single strand positive sense, 11Kb genome. The RNA is translated into a polyprotein precursor, wich is cleaved into 3 structural proteins (C, prM e E) and 7 non-structural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B e NS5). The NS3 is a multifunctional protein, that besides to promote the polyprotein precursor cleavage, also have NTPase, helicase and RTPase activity. The NS3 needs a hydrophilic segment of 40 residues from the transmembrane NS2B protein (who acts like cofator) to realize this functions. Actually, there's no vacines available on the market, and the treatment are just symptomatic. The tetrapeptide inhibitor Bz-Nle-Lys-Arg-Arg-H (Ki de 5,8-7,0 M) was showed as a potent inhibitor μ for NS3prot in Dengue virus. That is a inteligent alternative to treat the dengue desease. The present work aimed analyse the interactions of the ligand bounded to the activity site to provid a clear and depth vision of that interaction. For this purpouse, it was conducted an in silico study, by using quantum mechanical calculations based on Density Functional Theory (DFT), with Generalized Gradient approximation (GGA) to describe the effects of exchange and correlation. The interaction energy of each amino acid belonging to the binding site to the ligand was calculated the using the method of molecular fragmentation with conjugated caps (MFCC). Besides energy, we calculated the distances, types of molecular interactions and atomic groups involved. The theoretical models used were satisfactory and show a more accurate description when the dielectric constant = 20 ε and 80 was used. The results demonstrate that the interaction energy of the system reached convergence at 13.5 A. Within a radius of 13,5A the most important residues were identified. Met49, Met84 and Asp81 perform interactions of hydrogen with the ligant. The Asp79 and Asp75 residues present high energy of attraction. Arg54, Arg85 and Lys 131 perform hydrogen interactions with the ligand, however, appear in BIRD graph having high repulsion energy with the inhibitor. The data also emphasizes the importance of residue Tyr161 and the involvement of the catalytic triad composed by Asp75, His51 and Ser135
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Innovation has become an increasingly central issue of great reputation, not only in literature but also in management practices, becoming a strategic issue for managers of organizations. Allied to this, there is a high degree of competitiveness on the market, which contributes to the complexity of decision making, since managers need to maintain a continuous cycle of renewal processes and products. Thus, market pressures for new alternatives encourage innovation within organizations as a foundation for culture change in pursuit of survival and increased competitiveness, making it essential to know the factors that promote the advancement of organizational environments targeted innovation. Confirming this view, Bouchikhi and Kimberly (2001) symbolically expressed the idea with two statements: (1) companies need to innovate to survive, otherwise they die; and (2) the wide recognition of this need, as well as the difficulty to encourage and support innovation and entrepreneurship in business, has generated a mini-industry research and consulting in management focused on these topics. This study is characterized as descriptive with qualitative and quantitative methods. As for the planning of the research, it was decided to bibliographical research and the case study. The research, developed here, is meant to examine the organizational environment of a laboratory focused on technological innovation in health, which is a reference in research and technology of Rio Grande do Norte, and ensure that it presents opportunities to develop innovations. Therefore, the technologies developed by the Laboratório de Inovação Tecnológica em Saúde - LAIS/UFRN were mapped and then a questionnaire with the stakeholders of LAIS/UFRN was applied. This questionnaire is closed and Likert scale. As a result, it follows that the dimensions 1, 6, 7 and 8 are the most influential to form an innovative environment at LAIS.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
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Triamcinolone is a relevant anti-inflammatory costicosteroid drug, used mainly by injectable suspensions due its poor water solubility. The association of triamcinolone with cyclodextrins and co-solvents (triethanolamine TEA and N-methylpirrolidone NMP) was held to solubilize the drug and explain the involved interactions. Phase-solubility diagrams showed that triamcinolone was solubilized forming incredible stable complexes with cyclodextrins, in which bests results were observed applying randomyl-methylated-beta-cyclodextrin (RMβCD) (161 fold on increased solubility). The co-solvents TEA and NMP also enhanced drug solubility 1.4 and 6.7 fold, respectively. The association of both co-solvents with CDs seems decreased complexation stability, but enables higher amount of uncomplexed drug. Experimental magnetic resonance 2D-ROESY and theoretical molecular modeling studies demonstrated TRI-CDs interactions and elucidated the structure of formed complex, which occurred due to the inclusion of ring A of TRI on CDs cavity. Physicochemical aspects of solid binary and ternary complexes prepared by spray drying were assessed by using FTIR, X-ray diffraction and SEM photographs. Dissolution studies showed that binary and ternary associations presented higher dissolution efficacy in detrimental to pure drug system. In addition, the ternary complex containing TEA and RMβCD allowed drug dissolution faster than binary complex with RMβCD. Therefore, given the higher solubility and drug dissolution rate, binary and ternary complexes are new raw materials with great potential for pharmaceuticals containing triamcinolone.
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As we are aware, the classroom is emerging as a continuous build learning experiences and environment, however, for students also it functions as a place also to be due to socializing with friends. However, not always these elements complement each other, so as harmoniously as we are aware that there are many difficulties, both in the act of learning as in interpersonal relations between them. From this, we understand that it is for the school to seek ways to contemplate such issues so that they feel inserted both with regard to this learning as well as being able to interact with themselves and with others, in a participatory manner, to live well socially. Thus, we find ourselves facing a similar situation with a 9th grade class where the students had certain limitations to have a good relationship with one another, causing thus problems in learning. On the other hand, this difficulty as affectively interact with each other, also, was increased by the difficulty that some students had to speak for themselves and to show their feelings and emotions, getting even more difficult this interaction at school. Thus, we found ourselves obliged to act immediately and need to bring about change in this picture. So it came out the idea of the application of an intervening action which started taking shapefrom a pedagogical project that we developed in other classes in previous years, this time adapted to the situation experienced by the group. The project, framed in the qualitative research and characterized from the action research approach took shape, and elected as its main objective to seek possible alternatives to develop the communicative competence of students, which is why we invest in exercise oral communication (speaking and listening) in order to promote the use of language, the interpersonal involvement facilitating thus their participation both in the classroom and in social life. To fulfill this goal, we set out to develop a didactic book whose support materialized through the autobiographical narrative (molded in writing production) and worked along a structured instructional sequence in three distinctstages that dialogued with each other. Therefore, we base our study from the socio-historical conception and dialogue proposed by Bakhtin in line with the sociodiscursivo interactionism of Bronckart and resort to other scholars as Dolz and Schneuwly, Marcuschi among others. The development of all stages of the project not only has had an immediate effect on what we proposed ourselves as also yielded us very gratifying moments reinforcing to us that the classroom environment goes far beyond the fact ministering content. And that work with orality, with views on affective interaction of these students resulted in a project, so to speak, exciting.
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La Escuela Secundaria es la etapa final de la Educación Básica y su objetivo es profundizar los conocimientos adquiridos anteriormente, con vistas tanto a la continuidad de los estudios por parte de los alumnos como también a su formación profesional. Considerando el carácter excluyente y elitista de la Escuela Secundaria brasileña, solo recientemente las matrículas de los estudiantes sordos comienzan a ampliarse, y los profesores se deparan con el desafío de lidiar con ese tipo de discente en aulas regulares. Tanto la política de educación especial, desde una perspectiva inclusiva, como la Ley nº 10.436/2002 – reglamentada por el Decreto nº 5.626/2005 – posibilitaron un gran salto para la educación de los sordos en el país. La primera, por la defensa de una escuela atenta a las peculiaridades y demandas de sus discentes; la segunda, por reconocer la Lengua de Señas Brasileña como medio de comunicación y expresión legítimo de la comunidad de sordos y por indicar medidas que garanticen el derecho al acceso y al éxito escolar de la población sorda dentro de la escuela. Amparado en esas discusiones, este estudio tuvo como objetivo analizar el proceso de escolaridad de alumnos sordos de una Escuela Secundaria pública y estatal del municipio de Natal, Rio Grande do Norte. Se realizó un estudio de caso de tipo cualitativo. Los sujetos fueron tres discentes sordos que estaban terminando la Escuela Secundaria, una profesora de Portugués y dos intérpretes de Lengua de Señas Brasileña. Como procedimiento de investigación, se utilizaron entrevistas (grabadas en audio y video), observaciones y análisis de documentos. La participación de los sujetos sordos demandó cuidados éticos adicionales, tales como la traducción del Término de Consentimiento Libre y Aclarado y del guion de la entrevista a la Lengua de Señas Brasileña. Los resultados apuntan que el acceso y la permanencia en la escuela secundaria fueron garantizados, no obstante había poca participación en las clases y el aprendizaje de los contenidos escolares estaba comprometido. Había traductores/intérpretes de Lengua de Señas Brasileña, los cuales, sin embargo, solo iniciaron sus actividades tres meses después del comienzo del periodo lectivo. La profesora y los intérpretes no mantuvieron interacciones que facilitasen el aprendizaje o la participación de los estudiantes, quienes se encontraban siempre juntos y en un lugar determinado del aula, sin mayores interacciones con sus pares normo-oyentes. Los discentes sordos estaban terminando la Escuela Secundaria con edades superiores a 17-18 años, los cuales revelaron no tener perspectivas de continuidad en sus estudios o de inserción en el mercado laboral. Se concluye que la escolaridad de los alumnos sordos en la escuela investigada apunta a la necesidad de una reorganización curricular que atienda a las especificidades lingüísticas y sociales de esos estudiantes.
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The process mapping is an important tool in the management of organizations, allowing better levels of productivity, quality and reciprocity concerning the implementation and decision-making. It benefits in a clear way the process organization and assures the manager a macro vision of the system. In this sense, the objective of this study is to describe the mapping process as it occurs in the Januario Cicco Maternity School–MEJC. The bibliographic and descriptive research included interviews, observations and researches in many databases. The study analyzed the limiting points of the detected flow trying to find a better comprehension of the flow of patients in the maternity in order to offer the gestors the information necessary to improve the quality of the assistance as well as a general view of the flow of patients and any change detected there. As a result, we believe that the process mapping may become a relevant factor to the organizational management of MEJC, in view that it is an element that can contribute to ease up the management of information studied, considering that the perfect change of information inside a complex system will produce improvements in all spheres of this institution.
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Relatório de Estágio apresentado para obtenção do grau de Mestre na área de Ensino do 1.º ciclo e do 2.º ciclo do Ensino Básico
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In this paper, we will address together the magnetic and electrical properties of a particular semiconductor, the GaMnAs. The treatment will be done analytically in the first part of the work, according to the computational method for simulation of physical systems through the implementation of the expressions obtained in the first part. All study of magnetic contribution will be made using an interaction Kondo type, using an approach by Green functions. The electrical part, which consists of the Coulomb interactions between carriers and Mn ions, will be treated within the approach of multiple scattering. The implementation of the proposed method will calculate the Green functions converged as multiple scattering solution and use them as a starting point for the calculation of the effective magnetic interactions between Mn ions mediated charge carriers. The concentration parameters were varied for Mn ions and carriers as well. The combination of these two parameters can lead to insulating, metal samples with carriers in Fermi level to low or high mobility. As a result a correlation between the obtained carrier mobility and the strength of magnetic interaction. The greater mobility, the greater the intensity of the interaction.
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El propósito de este trabajo fue realizar una serie de estudios psicológicos sobre el estatus social humano, las decisiones de intervención en un conflicto hipotético entre pares; presentado por medio de un dilema social y las posibles consecuencias de tales decisiones. Para este fin, se investigaron muestras de jóvenes universitarios de dos distintas procedencias: Madrid, España y San José, Costa Rica. El estatus social es una de las variables que más frecuentemente se ha relacionado con las intervenciones durante los conflictos. Dada la importancia de la misma, el primer estudio empírico procedió a recabar evidencias de calidad de una medición de estatus social auto-percibido, esta estuvo compuesta por dos subescalas: dominancia auto-percibida y prestigio auto-percibido. Los procedimientos de validación incluyeron la traducción inversa inglés-español del instrumento así como procedimientos analíticos descriptivos, de diferencias de grupos, análisis factoriales exploratorios, análisis confirmatorios, análisis de congruencia e invarianza factorial, análisis de fiabilidad y análisis correlacionales con otras variables criterio (estrategia de historia de vida, dimensiones de la empatía y deseabilidad social). Los resultados mostraron que el modelo bidimensional de estatus (dominancia y prestigio cultural) era adecuado para ambos contextos estudiados. Por otra parte, los resultados obtenidos en los análisis correlacionales de la dominancia y el prestigio con las variables criterio fueron menos consistentes entre las diferentes muestras...
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Neospora caninum is an obligate intracellular parasite classified in the phylum Apicomplexa, characterized by the presence of the apical complex composed by micronemes proteins, rhoptries and dense granules, used by parasite during the adhesion and invasion process of the host cell. This is the mean event in infection pathogenesis generated by N. caninum and other parasites from the phylum Apicomplexa, promoting influence in the parasite biology and the interface between the parasite and its host. Therefore, molecular tools have been developed in order to identify and characterize these possible virulence factors. Thus, the present study sought to establish a specific system of genetic manipulation of N. caninum, searching for the improvement of the genetics manipulation of this parasite. So, we developed genetically depleted N. caninum to Rop9 rhoptry using the pU6-Universal CRISPR-Cas9 plasmid of T. gondii modified by the insertion of Ku80. The Rop9 depleted parasite showed important during initial phase of invasion and replication of the parasite, however it was not characterized as a potential virulence fator for N. caninum. Furthermore, T. gondii proteins were expressed in N. caninum by the use of specific vectors for this parasite, showing an heterologous system for the study of Toxoplasma proteins, due to the fact that Gra15 or Gra24 of type II T. gondii and Rop16 of type I T. gondii were expressed in N. caninum tachyzoites in a stable way and keept its biological phenotype, as already presented the former parasite, that naturaly expresses these proteins. In addition, it was observed that N. caninum induced an inflammasome activation through NLRP3, ASC and Caspase-1. IL-1R/MyD88 demonstrated an indirect pathway in the control of parasite replication. Furthermore, it was observed that this activation is dependent of the potassium efflux and that different strains of N. caninum keep this activation profile. However, T. gondii strains block this activation, making necessary a prior signal in order to active the inflamosome pathway. Type I T. gondii Rop16 was identified as responsible for blocking this activation, in a dependent way to the STAT3 activation. Therefore, the development of molecular tools and their application in N. caninum may prove to be useful to identify and characterize virulent factors involved in the pathogenesis by these two protozoans.