Self-assembled arginine-coated peptide nanosheets in water

The surfactant-like peptide (Ala)6(Arg) is found to self-assemble into 3 nm-thick sheets in aqueous solution. Scanning transmission electron microscopy measurements of mass per unit area indicate a layer structure based on antiparallel dimers. At higher concentration the sheets wrap into unprecedented ultrathin helical ribbon and nanotube architectures.

Jini meets the Grid

There is an increasing interest in integrating Java-based, and in particular Jini systems, with the emerging Grid infrastructures. In this paper we explore various ways of integrating the key components of each architecture, their directory and information management services. In the first part of the paper we sketch out the Jini and Grid architectures and their services. We then review the components and services that Jini provides and compare these with those of the Grid. In the second part of the paper we critically explore four ways that Jini and the Grid could interact, here in particular we look at possible scenarios that can provide a seamless interface to a Jini environment for Grid clients and how to use Jini services from a Grid environment. In the final part of the paper we summarise our findings and report on future work being undertaken to integrate Jini and the Grid.

A benchmark-driven modelling approach for evaluating deployment choices on a multi-core architecture

The complexity of current and emerging architectures provides users with options about how best to use the available resources, but makes predicting performance challenging. In this work a benchmark-driven model is developed for a simple shallow water code on a Cray XE6 system, to explore how deployment choices such as domain decomposition and core affinity affect performance. The resource sharing present in modern multi-core architectures adds various levels of heterogeneity to the system. Shared resources often includes cache, memory, network controllers and in some cases floating point units (as in the AMD Bulldozer), which mean that the access time depends on the mapping of application tasks, and the core's location within the system. Heterogeneity further increases with the use of hardware-accelerators such as GPUs and the Intel Xeon Phi, where many specialist cores are attached to general-purpose cores. This trend for shared resources and non-uniform cores is expected to continue into the exascale era. The complexity of these systems means that various runtime scenarios are possible, and it has been found that under-populating nodes, altering the domain decomposition and non-standard task to core mappings can dramatically alter performance. To find this out, however, is often a process of trial and error. To better inform this process, a performance model was developed for a simple regular grid-based kernel code, shallow. The code comprises two distinct types of work, loop-based array updates and nearest-neighbour halo-exchanges. Separate performance models were developed for each part, both based on a similar methodology. Application specific benchmarks were run to measure performance for different problem sizes under different execution scenarios. These results were then fed into a performance model that derives resource usage for a given deployment scenario, with interpolation between results as necessary.

Ethics education in management accounting studies: evidence from business schools in Ghana

Management accounting in recent times, and perhaps rightly so, has begun to gain recognition as a profession separate and complimentary to financial accounting. Evidence exists to suggest that management accountants are exposed to a unique set of ethical challenges within industry and that a significant high number of management accountants have engaged in unethical practices in performing their jobs. For the accounting profession as a whole, the growing number of corporate failures has created a credibility crisis that requires a deliberate intervention to mitigate. If this is not addressed sooner, the accounting profession stands the risk of losing relevance. Scholarship on ethical issues in accounting practice have either focused mostly on financial accounting or have sought to combine ethical issues for financial and management accounting. Various arguments have been made in recent times of the need to treat ethical issues in behavioural studies as context-specific and therefore separate ethical considerations in management accounting from financial accounting. This study adopts an approach, following various literature, that effective ethics education can help practitioners deal appropriately with ethical issues at the work place, and explores students’ and faculty members’perceptions on current practices in ethics education. As expected, faculty and students differ significantly on a wide range of issues on ethics education in management accounting. Based on the insights provided from this study, appropriate recommendations have been made to improve ethics education in management accounting.

Azotobacter genomes: the genome of Azotobacter chroococcum NCIMB 8003 (ATCC 4412)

The genome of the soil-dwelling heterotrophic N2-fixing Gram-negative bacterium Azotobacter chroococcum NCIMB 8003 (ATCC 4412) (Ac-8003) has been determined. It consists of 7 circular replicons totalling 5,192,291 bp comprising a circular chromosome of 4,591,803 bp and six plasmids pAcX50a, b, c, d, e, f of 10,435 bp, 13,852, 62,783, 69,713, 132,724, and 311,724 bp respectively. The chromosome has a G+C content of 66.27% and the six plasmids have G+C contents of 58.1, 55.3, 56.7, 59.2, 61.9, and 62.6% respectively. The methylome has also been determined and 5 methylation motifs have been identified. The genome also contains a very high number of transposase/inactivated transposase genes from at least 12 of the 17 recognised insertion sequence families. The Ac-8003 genome has been compared with that of Azotobacter vinelandii ATCC BAA-1303 (Av-DJ), a derivative of strain O, the only other member of the Azotobacteraceae determined so far which has a single chromosome of 5,365,318 bp and no plasmids. The chromosomes show significant stretches of synteny throughout but also reveal a history of many deletion/insertion events. The Ac-8003 genome encodes 4628 predicted protein-encoding genes of which 568 (12.2%) are plasmid borne. 3048 (65%) of these show > 85% identity to the 5050 protein-encoding genes identified in Av-DJ, and of these 99 are plasmid-borne. The core biosynthetic and metabolic pathways and macromolecular architectures and machineries of these organisms appear largely conserved including genes for CO-dehydrogenase, formate dehydrogenase and a soluble NiFe-hydrogenase. The genetic bases for many of the detailed phenotypic differences reported for these organisms have also been identified. Also many other potential phenotypic differences have been uncovered. Properties endowed by the plasmids are described including the presence of an entire aerobic corrin synthesis pathway in pAcX50f and the presence of genes for retro-conjugation in pAcX50c. All these findings are related to the potentially different environmental niches from which these organisms were isolated and to emerging theories about how microbes contribute to their communities.

Counting in Egyptian children with Down Syndrome

This exploratory study is concerned with the performance of Egyptian children with Down syndrome on counting and error detection tasks and investigates how these children acquire counting. Observations and interviews were carried out to collect further information about their performance in a class context. Qualitative and quantitative analysis suggested a notable deficit in counting in Egyptian children with Down syndrome with none of the children able to recite the number string up to ten or count a set of five objects correctly. They performed less well on tasks which added more load on memory. The tentative finding of this exploratory study supported previous research findings that children with Down syndrome acquire counting by rote and links this with their learning experiences.

Black-box decomposition approach for computational hemodynamics: One-dimensional models

Increasing efforts exist in integrating different levels of detail in models of the cardiovascular system. For instance, one-dimensional representations are employed to model the systemic circulation. In this context, effective and black-box-type decomposition strategies for one-dimensional networks are needed, so as to: (i) employ domain decomposition strategies for large systemic models (1D-1D coupling) and (ii) provide the conceptual basis for dimensionally-heterogeneous representations (1D-3D coupling, among various possibilities). The strategy proposed in this article works for both of these two scenarios, though the several applications shown to illustrate its performance focus on the 1D-1D coupling case. A one-dimensional network is decomposed in such a way that each coupling point connects two (and not more) of the sub-networks. At each of the M connection points two unknowns are defined: the flow rate and pressure. These 2M unknowns are determined by 2M equations, since each sub-network provides one (non-linear) equation per coupling point. It is shown how to build the 2M x 2M non-linear system with arbitrary and independent choice of boundary conditions for each of the sub-networks. The idea is then to solve this non-linear system until convergence, which guarantees strong coupling of the complete network. In other words, if the non-linear solver converges at each time step, the solution coincides with what would be obtained by monolithically modeling the whole network. The decomposition thus imposes no stability restriction on the choice of the time step size. Effective iterative strategies for the non-linear system that preserve the black-box character of the decomposition are then explored. Several variants of matrix-free Broyden`s and Newton-GMRES algorithms are assessed as numerical solvers by comparing their performance on sub-critical wave propagation problems which range from academic test cases to realistic cardiovascular applications. A specific variant of Broyden`s algorithm is identified and recommended on the basis of its computer cost and reliability. (C) 2010 Elsevier B.V. All rights reserved.

An aspect-oriented reference architecture for Software Engineering Environments

Reusable and evolvable Software Engineering Environments (SEES) are essential to software production and have increasingly become a need. In another perspective, software architectures and reference architectures have played a significant role in determining the success of software systems. In this paper we present a reference architecture for SEEs, named RefASSET, which is based on concepts coming from the aspect-oriented approach. This architecture is specialized to the software testing domain and the development of tools for that domain is discussed. This and other case studies have pointed out that the use of aspects in RefASSET provides a better Separation of Concerns, resulting in reusable and evolvable SEEs. (C) 2011 Elsevier Inc. All rights reserved.

Inovação e criatividade nas pequenas e médias empresas

The importance of small and medium enterprises for the economy of a country is fundamental because they have several strategic social and economic roles. Besides contributing to the production of national wealth, they also counterbalance the vulnerabilities of large companies providing the necessary economic balance. Socially their contribution is directly related to the lessening of unemployment, functioning also as source of stability in the community, as a means of reducing inequalities in the distribution of income among regions and economic groups, and contributes, decisively, to limit migration to urbans area. The capacity to innovate is now a key component for the survival and development of small organizations. The future today is increasingly less predictable using past parameters and the business world is more turbulent. The objective of this is to point out the need to revise the models which serve as examples for their adoption of competitive alternatives of development and to offer theoretical-practical knowledge to make possible the implementation of the innovative culture in small enterprises. It emphasizes, moreover, that in the present context, flexibility and skills to work in ambiguous situations and to find creative solutions become central concerns of businessmen and managers.

Impactos emocionais causados pela mudança de estilo de gestão em um hospital na cidade de São Luis-MA

The objective of this study is to identify how a health institution can minimize the emotional impacts caused by the change of a style of classic management for a participative administration, that the workers and controllers can see the institution as a dynamic organization, that must be faced as an alive system, mobile and adaptable, where they is beings that have the right to react and to answer to the stimulatons. For that, the institution can handle motivator¿s instruments that develop in the people the potential to react of adequate way to the changes proposals, as well as increasing the perspective of possible technological improvements and interpersonal relationship between the internal and external customers. To change the style to manage, to hear the staff of support and user, are not part of the routine of the heads that develop classic management. This decision demands adaptation and flexibility, study, update and psychological preparation, to face common feelings to the new. It fits to the new directors, to visualize these feelings and work to minimize, avoiding future upheavals and the confrontation of situations that can harm the production of the company, as well as the quality of the communication between the diverse dimensions of the organization people. In this study case, based in phenomenological methodology, was possible to verify, through half-open interviews and comments, how was faced the feelings caused at the old direction time, composed for military who withheld the power and determined the actions of the hospital in study, was replaced by health professionals, that saw in the work team the best option to solve the problems and the potential to carry through an administration based in adequate strategies the reality of the moment, with the objective of reaching the satisfaction of the customer. Through this work, is possible to prove the theory that the changes cause impacts that affect the behavior of the people involved and cause stress, as well as conclude that despite the new direction show themselves, during the change, much made use to make right and involve all the workers, didn¿t have traced strategies to minimize the emotional impacts caused by the changes, what made all face their feelings of doubts and anxiety without no special care. Many obtained, by themselves, to face and to adapt the new proposals, but some could not assimilate the new administrative methodology and had been moved away definitively from the institution.

Fatores que impactam a implantação de tecnologias de gestão baseadas em processos em uma empresa pública

O mundo está passando por grandes mudanças que vêm afetando as esferas sociais, tecnológicas, empresariais e mentais. As empresas têm sido ameaçadas por diversos fatores como rapidez no lançamento de novos produtos, interferência dos governos, clientes cada vez mais conscientes e exigentes, aumento da concorrência, globalização e o surgimento constante de novas tecnologias. Essas mudanças exigem das empresas uma estrutura mais flexível capaz de absorver as rápidas necessidades do ambiente, e o formato atual não tem se mostrado adequado para vencer estes desafios. Nesse contexto, a gestão baseada em processos tem se mostrado promissora ao ser incorporada nas principais tecnologias de gestão como BSC, NBR ISO 9000, gestão de custos com ABC, entre outras. Como toda nova abordagem, as tecnologias (ou modelos) baseadas em processos sofrem de vários problemas, sendo alguns já conhecidos, como resistência às mudanças, falta de preparo e apoio insuficiente da alta direção. Os estudos desses fatores são incipientes e em sua maioria não tratam de seus impactos em empresas públicas. Esse trabalho tem como objetivo justamente identificar esses fatores na literatura (teoria e casos de estudo) e confrontá-los com aqueles encontrados em uma empresa pública (estudo de caso), analisando sua pertinência. Os resultados encontrados, além de confirmarem os fatores, sugerem que a sua utilização, na forma de um checklist, podem beneficiar as empresas na prevenção, redução ou eliminação de problemas que impactam ou inviabilizam um projeto.

Crowding no varejo: diferenças na satisfação e percepção de valor hedônico de consumidores de alta e baixa renda no Brasil

Esta investigação visa o melhor entendimento do fenômeno do crowding em lojas, dentro do contexto do mercado brasileiro, procurando identificar como as respostas dos consumidores variam entre os de renda baixa e renda alta, e buscando fatores que possam melhor explicar essas diferenças. Para atender esses objetivos, adotou-se uma metodologia experimental para testar como o aumento da densidade humana afeta diferentemente as respostas dos consumidores de alta e baixa renda. Como moderadoras da relação entre densidade humana e as respostas de consumidores, utilizaram-se as variáveis renda (alta e baixa) e familiaridade (alta e baixa). Três experimentos de desenhos fatoriais permitiram o teste das hipóteses propostas, por meio de análises multivariadas: ANOVAs, ANCOVAs e regressões lineares. Os estudos demonstraram que renda efetivamente modera as respostas dos consumidores, pois existe substancial diferença entre os consumidores de alta e baixa renda para situações de alta densidade humana em lojas. Foram verificadas as seguintes respostas dos consumidores com menor renda em situações de alta densidade humana: atitude mais positiva e maior nível de satisfação do que os de alta renda; percepção de maior valor hedônico em lojas mais cheias de gente versus os de maior renda. Os resultados contrariam a maioria dos achados de estudos realizados nos Estados Unidos nas últimas décadas. Enquanto a maioria desses estudos indica uma resposta negativa à densidade humana, os resultados desta pesquisa evidenciaram que existem respostas mais positivas para o segmento econômico de consumidores de baixa renda. Constatou-se também o efeito moderador do controle informacional (familiaridade) na relação entre densidade humana e as respostas dos consumidores, e o efeito mediador da percepção de valor hedônico na relação entre densidade e satisfação. Os achados oferecem uma contribuição teórica para enriquecer o entendimento do fenômeno de crowding e ressaltam a importância de se considerar a diversidade do contexto socioeconômico para se garantir o desenvolvimento de generalizações que corretamente reflitam as várias realidades do mercado. Do ponto de vista gerencial, o estudo reforça a necessidade de o varejo desenvolver uma maior distinção em ambientes de loja para melhor satisfazer as diferentes preferências dos diversos segmentos de mercado.

The market strategies alternatives of an e-business start-up in Brazil

The e-business market is one of the fastest growing markets in Brazil, with e-business sales accounting for BRL 14.8 billion in 2010 and a growth of 40% per year (+1000% over the past 7 years). Sales-event clubs and collective bargaining websites are one of the most dynamic segments of the e-business market: the number of new players is increasing rapidly, with over 1200 collective bargaining websites currently operating in Brazil. In that context, growth and differentiation seem to be two key success factors for Coquelux. According to webshopper (23rd Edition, e-bit), growth can be achieved by targeting middle and low-income consumers from class C, who represent 50% of the total e-commerce sales. But Coquelux, which is specialized in desire and luxury brands, has built its reputation and competitive advantage through its “exclusivity”, by targeting wealthier consumers from classes A and B who are attracted by its fashionable and high-end positioning. The evolution (growth?) of this market and the development of its competition naturally raise a strategic question for Coquelux’s managers: can Coquelux grow and still maintain its competitive advantage? Should it grow by expanding its consumer base to class C? If so, how? Consumers from classes A, B or C must be targeted through the same online communication channels. Recent studies from the ABEP/ABIPEME emphasized the importance of social networks as a tool for converting new clients and gaining their loyalty, regardless of their social class. However, high-income and low-income e-consumers do not have the same consumption habits, do not respond to the same type of marketing strategies, and most importantly, do not share the same values. Thus, it seems difficult to expand Coquelux’s consumer base to class C without changing its marketing strategies and altering its image Three options were identified for Coquelux: reinforcing its leadership on the luxury segment and focusing on a small niche market (1), which would threaten its survival in the long run; completely changing its strategy and competing for a mass market through commercial brands (2), which requires major financial investments that managers don’t have access to; or finding an intermediary solution (3). This thesis’ recommendation for the third option consists in focusing on premium brands (rather than luxury) in order to increase sales volume (Coquelux’s most profitable sales happened with local desire brands) with products that appeal to class B but also attract the emerging class C which is looking for brand recognition. It could thus implement a slow entry strategy towards the mass market without damaging its main competitive advantage.

Adoção do modelo MVNO no Brasil e consequências para a cadeia de valor de telecomunicações móveis

O modelo de negócio MVNO, acrônimo em inglês para operadoras móveis virtuais, foi introduzido no Brasil em Novembro de 2010 por uma regulamentação específica, visando aumentar a qualidade dos serviços e a competição entre as empresas do setor de Telecomunicações Móveis. O objetivo deste estudo é avaliar o fenômeno MVNO em seu estágio atual de adoção no Brasil, contrapondo as óticas dos atores de mercado, às teorias de Cadeia de Valor (PORTER, 1985), e decupagem da Cadeia de Valor (CHRISTENSEN et al, 2001; ANDERSON; WILLIAMS, 2004). Por se tratar de um fenômeno intrinsecamente ligado à desagregação de atividades de valor, em uma indústria originalmente verticalizada, a análise se concentrou nessa dinâmica, mas não se limitou a ela: o estudo também traz comparações com casos de MVNO estudados em diversos países e outras referências teóricas do campo da Tecnologia da Informação e Comunicação, tais como Economia da Informação (SHAPIRO; VARIAN, 1999), Inovação Disruptiva (CHRISTENSEN; BOWER, 1999), e Dimensões da Inovação (SAWHNEY et al, 2011). A pesquisa se baseou nas categorias conceituais da Abordagem Multinível (POZZEBON; DINIZ, 2011) – Contexto, Processo e Conteúdo – buscando conhecer os perfis e interesses de cada Grupo Social Relevante e a negociação entre os envolvidos. A partir dessa articulação, foi possível compreender o fenômeno e algumas de suas consequências para o cenário brasileiro de Telecomunicações Móveis, destacando-se entre os resultados encontrados: as linhas gerais da nova Cadeia de Valor em formação, a influência decisiva de um grupo social relevante para a adoção do modelo – os MVNE, que são integradores de MVNOs à estrutura das operadoras – e a utilização da regulação para incentivar negócios com aplicações máquina a máquina (M2M). A descrição do modelo e das características que vem assumindo no Brasil proporcionam insumos tanto para praticantes do mercado, quanto para acadêmicos. Estes últimos podem se beneficiar, além de um ponto de partida para pesquisas futuras sobre MVNO no Brasil, de uma inédita articulação da Abordagem Multinível com a teoria de Cadeia de Valor

Engajamento do consumidor em uma comunidade virtual de marca

O estudo objetivou a investigação do fenômeno de engajamento do consumidor em uma comunidade virtual de marca, tendo a Fan Page da L'Oréal Paris Brasil como contexto de observação. Para isso, por meio de método netnográfico, foram coletadas as interações entre os membros da comunidade ao longo de três meses e analisadas sob a perspectiva do modelo conceitual apresentado por Brodie et al. (2011b). Durante a análise de conteúdo, considerando as técnicas propostas por Bardin (2007), foram identificadas as dimensões, os processos e sub-processos do engajamento do consumidor, conforme proposto pelo modelo conceitual. Além disso, os resultados encontrados apontam para a validação do modelo e reforçam a perspectiva de que a simples participação ou envolvimento não pressupõe engajamento, pois este reflete um estado psicológico complexo, dependente de contexto e que necessita de processos antecedentes e consequentes. Com base nos achados, são discutidas as implicações teóricas e práticas, assim como sugestão para futuros estudos sobre o tema.