Diverse set of Turing nanopatterns coat corneae across insect lineages.

Nipple-like nanostructures covering the corneal surfaces of moths, butterflies, and Drosophila have been studied by electron and atomic force microscopy, and their antireflective properties have been described. In contrast, corneal nanostructures of the majority of other insect orders have either been unexamined or examined by methods that did not allow precise morphological characterization. Here we provide a comprehensive analysis of corneal surfaces in 23 insect orders, revealing a rich diversity of insect corneal nanocoatings. These nanocoatings are categorized into four major morphological patterns and various transitions between them, many, to our knowledge, never described before. Remarkably, this unexpectedly diverse range of the corneal nanostructures replicates the complete set of Turing patterns, thus likely being a result of processes similar to those modeled by Alan Turing in his famous reaction-diffusion system. These findings reveal a beautiful diversity of insect corneal nanostructures and shed light on their molecular origin and evolutionary diversification. They may also be the first-ever biological example of Turing nanopatterns.

A novel set of DIP-STR markers for improved analysis of challenging DNA mixtures.

Currently available molecular biology tools allow forensic scientists to characterize DNA evidence found at crime scenes for a large variety of samples, including those of limited quantity and quality, and achieve high levels of individualization. Yet, standard forensic markers provide limited or no results when applied to mixed DNA samples where the contributors are present in very different proportions (unbalanced DNA mixtures). This becomes an issue mostly for the analysis of trace samples collected on the victim or from touched objects. To this end, we recently proposed an innovative type of genetic marker, named DIP-STR that relies on pairing deletion/insertion polymorphisms (DIP) with standard short tandem repeats (STR). This novel compound marker allows detection of the minor DNA contributor in a DNA mixture of any gender and cellular origin with unprecedented resolution (beyond a DNA ratio of 1:1000). To provide a novel analytical tool useful in practice to common forensic laboratories, this article describes the first set of 10 DIP-STR markers selected according to forensic technical standards. The novel DIP-STR regions are short (between 146 and 271 bp), include only highly polymorphic tri-, tetra- and pentanucleotide tandem repeats and are located on different chromosomes or chromosomal arms to provide statistically independent results. This novel set of DIP-STR can target the amplification of 0.03-0.1 ng of DNA when mixed with a 1000-fold excess of major DNA. DIP-STR relative allele frequencies are estimated based on a survey of 103 Swiss individuals. Finally, this study provides an estimate of the occurrence of informative alleles and a calculation of the corresponding random match probability of the detected minor DIP-STR genotype assessed across 10,506 pairwise conceptual mixtures.

The motivation to learn as a self-presentation tool among Swiss high school students : The moderating role of mastery goals' perceived social value on learning

Although it has been assumed that the motivation to learn - or mastery goal endorsement - positively predicts learning achievement, most empirical findings fail to demonstrate this relationship. In the present research, conducted in a Swiss high school, we adopted a social value approach to test the hypothesis that adolescent students' mastery goals do in fact predict learning, but only if these goals are perceived as highly useful for scholarly success (high social utility), and are not endorsed as a means to be appreciated by the teachers (low social desirability), a finding that has previously been observed among college students and on teacher-graded achievement measures only. Results demonstrate that in spite of potential peculiarities of an adolescent population, individual differences in mastery goals' perceived social utility and desirability moderate the mastery goal endorsement-learning achievement relation. Findings are discussed with regard to both theory development and educational practice.

A minimal set of coordinates for describing humanoid shoulder motion

The kinematics of the anatomical shoulder are analysed and modelled as a parallel mechanism similar to a Stewart platform. A new method is proposed to describe the shoulder kinematics with minimal coordinates and solve the indeterminacy. The minimal coordinates are defined from bony landmarks and the scapulothoracic kinematic constraints. Independent from one another, they uniquely characterise the shoulder motion. A humanoid mechanism is then proposed with identical kinematic properties. It is then shown how minimal coordinates can be obtained for this mechanism and how the coordinates simplify both the motion-planning task and trajectory-tracking control. Lastly, the coordinates are also shown to have an application in the field of biomechanics where they can be used to model the scapulohumeral rhythm.

Llegint Cinema. Anàlisi de la representació de la malaltia mental en el setè art

El present treball és un estudi sobre l'estigma social en la malaltia mental i la representació d'aquest al cinema. Aquesta anàlisi s'ha portat a terme a partir de dues línies de treball. Per una banda amb l'anàlisi interpretativa de dotze pel·lícules utilitzant els indicadors de 'perillositat'; 'incapacitat per a la vida'; 'incurabilitat'; 'pèrdua de rols socials'; 'por al rebuig i/o por a les relacions socials'; i per l'altra banda a partir d'un grup de discussió, en el qual s'han visionat fragments de cinc pel·lícules amb set estudiants del Grau d'Educació Social de la Universitat de Vic. Dels resultats obtinguts es desprèn que la pel·lícula és un mitjà de comunicació mitjançant el qual els estereotips són usats en favor de l'espectacle, estigmatitzant així les persones diagnosticades de malaltia mental. Aquest és un dels motius que fan valorar el cinema com un recurs educatiu a considerar tant en la formació d'educadors i educadores socials com en els projectes d'intervenció socioeducativa.

Palvelukonsernin Iiiketoimintayksikön suorituskyvyn mittaaminen

Kiristyvät markkinat ajavat yritykset tehostamaan toimintaansa. Suorituskyvyn mittaaminen on jo olennainen osa suomalaista yrityskulttuuria. Mittaamisen päätehtävä on tuottaa yritysjohdolle relevanttia informaatiota yrityksen tilasta ja auttaa valvomaan ja kehittämään toimintaa. Tämän tutkimuksen kohteena on palvelukonsernin Iiiketoimintayksikön suorituskyvyn mittaaminen. Tutkimuksen päätavoitteina on 1. valita palvelukonsernin liiketoimintayksikölle sopiva suorituskyvyn mittausjärjestelmä, 2. valita käytännöllinen implementointimalli sekä 3. laatia suorituskykymittaristo palvelukonsernin liiketoimintayksikölle. Tämä tutkimus jakautuu kahteen vaiheeseen. Ensimmäisessä vaiheessa tutkimuksen kohteena on suorituskyvyn teoria ja neljä erilaista mittausmenetelmää, joista valitaan yksi Iiiketoimintayksikön suorituskyvyn mittausjärjestelmäksi sekä syvempää tarkastelua varten. Tutkimuksen toisessa vaiheessa tutkitaan valitun mittausjärjestelmän ominaisuuksia strategisena johtamisjärjestelmänä sekä sen implementointimalleja. Toisen vaiheen keskeisin tutkimusosuus on suorituskykymittausjärjestelmän laadinta. Työn lopputuloksena syntyy palvelukonsernin Iiiketoimintayksikön suorituskyvyn mittausjärjestelmä sekä jatkotoimenpide-ehdotus Balanced Scorecardin laajentamiseksi Iiiketoimialan ohjausjärjestelmäksi.

Tuotannon kehitysinvestointiprojektien läpivientimalli

Tämän diplomityön tarkoituksena oli tutkia ja etsiä kehityskohteita kohdeyrityksen kehitysinvestointiprojektien toimintamallissa. Diplomityön tavoitteena oli tutkia nykyistä investointikäytäntöä ja luoda eri linjastoissa tehtäville kehitysinvestointiesityksille edellytykset tukea yhteisesti yrityksen tulevia suhdannenäkymiä ja strategiaa. Työn tavoitteena oli myös pyrkiä välillisesti kasvattamaan investointiin sijoitettavan pääoman tuottoprosenttia pienentämällä kustannuksia huolellisen valmistelun keinoin jo investointiprojektin kehityksen alkuvaiheessa. Työkaluksi tähän todettiin olevan läpivientimalli. Tutkimusmenetelminä käytettiin kvantitatiivisia ja kvalitatiivisia tiedonkeruumenenelmiä. Näistä ylemmän johdon ja keskijohdon haastattelut, sekä omat kokemukset yrityksen käytännöistä vuosilta 2004-2008 näyttelivät pääroolia. Työn tuotoksena laadittiin aiheeseen liittyvä ohjeistus ja läpivientimalli osaksi yrityksen laatujärjestelmää. Malli sijoitettiin template tyyppisesti dokumentinhallinnointiohjelmistoon. Työn tuloksena on esitetty kehitysinvestointiprojektien läpivientimalli siten, että se tukee yrityksen strategiaa kestävän kehityksen ympäröimänä. Työlle asetetut tavoitteet saavutettiin sille tarkoitetussa aikavälissä.

A Co-Processor Approach for Efficient Java Execution in Embedded Systems

This thesis deals with a hardware accelerated Java virtual machine, named REALJava. The REALJava virtual machine is targeted for resource constrained embedded systems. The goal is to attain increased computational performance with reduced power consumption. While these objectives are often seen as trade-offs, in this context both of them can be attained simultaneously by using dedicated hardware. The target level of the computational performance of the REALJava virtual machine is initially set to be as fast as the currently available full custom ASIC Java processors. As a secondary goal all of the components of the virtual machine are designed so that the resulting system can be scaled to support multiple co-processor cores. The virtual machine is designed using the hardware/software co-design paradigm. The partitioning between the two domains is flexible, allowing customizations to the resulting system, for instance the floating point support can be omitted from the hardware in order to decrease the size of the co-processor core. The communication between the hardware and the software domains is encapsulated into modules. This allows the REALJava virtual machine to be easily integrated into any system, simply by redesigning the communication modules. Besides the virtual machine and the related co-processor architecture, several performance enhancing techniques are presented. These include techniques related to instruction folding, stack handling, method invocation, constant loading and control in time domain. The REALJava virtual machine is prototyped using three different FPGA platforms. The original pipeline structure is modified to suit the FPGA environment. The performance of the resulting Java virtual machine is evaluated against existing Java solutions in the embedded systems field. The results show that the goals are attained, both in terms of computational performance and power consumption. Especially the computational performance is evaluated thoroughly, and the results show that the REALJava is more than twice as fast as the fastest full custom ASIC Java processor. In addition to standard Java virtual machine benchmarks, several new Java applications are designed to both verify the results and broaden the spectrum of the tests.

Statistical Optimum Design of Heat Exchangers

The optimal design of a heat exchanger system is based on given model parameters together with given standard ranges for machine design variables. The goals set for minimizing the Life Cycle Cost (LCC) function which represents the price of the saved energy, for maximizing the momentary heat recovery output with given constraints satisfied and taking into account the uncertainty in the models were successfully done. Nondominated Sorting Genetic Algorithm II (NSGA-II) for the design optimization of a system is presented and implemented inMatlab environment. Markov ChainMonte Carlo (MCMC) methods are also used to take into account the uncertainty in themodels. Results show that the price of saved energy can be optimized. A wet heat exchanger is found to be more efficient and beneficial than a dry heat exchanger even though its construction is expensive (160 EUR/m2) compared to the construction of a dry heat exchanger (50 EUR/m2). It has been found that the longer lifetime weights higher CAPEX and lower OPEX and vice versa, and the effect of the uncertainty in the models has been identified in a simplified case of minimizing the area of a dry heat exchanger.

Optimised Utilization of Bioenergy in Poland

The aim of the study was to ford out the availability of biomasses, which are available for energy production, in Poland. Biomasses which were examined were forest residues and surplus straw. Availability was examined by 16 Polish voivodeships, which are provinces in Poland. After fording out the amounts of biomasses for energy production was examined the need of biomass in the biggest CHP plants in Poland. It was expected that all the plants uses 15 % of biomass as the fuel. In the first parts of the report are explained the legislation which effects to biomass use in energy production in EU level and in Polish level. Also the combustion methods best for biomasses are explained by examples. After this, is studied the general situation of renewable energy use in Poland and the facts about the country. In the last parts it's explained the calculations and is shown the example cases. When it was found out the needs and supply of biomass it was examined by examples how it could be transported to the plants from the producers. Also was examined costs effected, if there were logistical terminals between the producer and the end user. The estimation was done by setting prices for the biomass, and fording out average costs for producing and transporting biomass. There are a lot of surplus biomasses in Poland which could be used for energy production, and this is a one way to reach the goals that EU has set of renewable energies. But because biomasses doesn't have such a good calorific value, it isn't worth able to transport it very long distances. In the research was set the prices for producer 9€/MWh and for end user 15€/MWh, the maximum transportation distance for forest residues was 52 km and for straw 56 km. These are example estimations and it has to be remembered that there are a lot of factors that makes inaccurate. The model is really sensitive and by changing one parameter the results change a lot.

Harjoitustöiden vertaisarviointi opetusvälineenä

Harjoitustöiden vertaisarvioinnissa opiskelijat tarkastavat toistensa töitä ja antavat niistä palautteen annettujen ohjeiden mukaan. Yleensä opiskelijoille annetaan tätä tehtävää tukemaan tietty joukko arviointikriteereitä, joiden osalta työtä ainakin on kommentoitava. Vertaisarviointi voi antaa opiskelijoille monipuolisempaa palautetta kuin ilman sitä olisi mahdollista, mahdollisuuden tehtävien vaihtoehtoisiin ratkaisuihin tutustumiseen sekä kokemusta ongelmanratkaisun analyyttisestä ja kriittisestä tarkastelusta. Lisäksi vertaisarviointi voi tukea opettajien työtä helpottamalla riittävän palautteen antamista opiskelijoille ja antamalla jonkinlaista kuvaa opiskelijoiden näkemyksistä tehtävän aihealueeseen liittyen. Tämän työn tavoitteena on selvittää, mitä mainituista vertaisarviointiin liitetyistä hyödyistä voidaan todellisuudessa saavuttaa ohjelmointipainotteisilla kursseilla. Ohjelmointikurssin opiskelijat arvioivat kurssiin kuuluvien harjoitustöiden yhteydessä toistensa ratkaisuja yhteen tehtävistä. Opiskelijoille suunnatulla kyselyllä pyritään kartoittamaan, kuinka hyvin vertaisarvioinnille asetetut tavoitteet toteutuvat. Kokemuksia opettajan näkökulmasta selvitetään haastattelujen avulla. Testauksen toteutuksessa käytetään verkkosovellusta, johon opiskelijat tallentavat omat työnsä, josta he lataavat itselleen määrätyt työt arvioitavaksi, johon he tallentavat arvionsa ja jonka kautta he lopulta saavat palautteen omasta työstään.

Jakelulogistiikan kustannustehokkuuden kehittäminen

Tämän diplomityön päätavoite on selvittää keinoja Woikoski Oy:n jakelulogistiikan kustannustehokkuuden kehittämiseksi. Päätavoite voidaan jakaa osatavoitteisiin, joita ovat varastonohjauksen kehittäminen ja jakelun kuljetustoimintojen tehostaminen. Varastoinnin nykytilaa arvioitiin ABC-analyysin avulla. Saatujen tulosten pohjalta määritettiin luokkakohtaiset varastonohjaussäännöt ja kiertonopeustavoitteet, jotka yhdessä muodostavat yritykselle varastopolitiikan. Havaitut ongelmat kulminoituivat jatkuvan varastoseurannan puuttumiseen, suuriin varastotasoihin sekä kysynnänhallinnan puutteisiin. Toimenpidesuosituksina yrityksen tulee investoida tehokkaaseen varastonhallintajärjestelmään sekä aloittaa systemaattinen kysynnän ennustaminen. Kuljetuksiin liittyviksi toimenpiteiksi ehdotetaan runko- ja jakelukuljetusten reittien sekä jakelualueiden optimointia ja tuloksena saadun jakelumallin käyttöönottoa. Nykyistä jakelurahtien hinnoittelua suositellaan tarkennettavaksi siten, että jakelukustannuksia ja toimitusmääriä eritellään nykyistä tarkemmin ja asiakkaille kohdistetaan rahtikustannuksia todenmukaisin perustein. Lisäksi logistiikkatoimintaa tulee yhtenäistää eri toimipaikkojen kesken ja toimintojen mittaamista on tehostettava organisaatiossa.

Invasive species and habitat degradation in Iberian streams: an analysis of their role in freshwater fish diversity loss

Mediterranean endemic freshwater fish are among the most threatened biota in the world. Distinguishing the role of different extinction drivers and their potential interactions is crucial for achieving conservation goals. While some authors argue that invasive species are a main driver of native species declines, others see their proliferation as a co-occurring process to biodiversity loss driven by habitat degradation. It is difficult to discern between the two potential causes given that few invaded ecosystems are free from habitat degradation, and that both factors may interact in different ways. Here we analyze the relative importance of habitat degradation and invasive species in the decline of native fish assemblages in the Guadiana River basin (southwestern Iberian Peninsula) using an information theoretic approach to evaluate interaction pathways between invasive species and habitat degradation (structural equation modeling, SEM). We also tested the possible changes in the functional relationships between invasive and native species, measured as the per capita effect of invasive species, using ANCOVA. We found that the abundance of invasive species was the best single predictor of natives’ decline and had the highest Akaike weight among the set of predictor variables examined. Habitat degradation neither played an active role nor influenced the per capita effect of invasive species on natives. Our analyses indicated that downstream reaches and areas close to reservoirs had the most invaded fish assemblages, independently of their habitat degradation status. The proliferation of invasive species poses a strong threat to the persistence of native assemblages in highly fluctuating environments. Therefore, conservation efforts to reduce native freshwater fish diversity loss in Mediterranean rivers should focus on mitigating the effect of invasive species and preventing future invasions