905 resultados para barrel cortex, plasticity, septa, development, Early motor activity, M1


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Scent-marking behavior is associated with different behavioral contexts in callitrichids, including signalizing a territory, location of feeding resources, and social rank. In marmosets and tamarins it is also associated with intersexual communication. Though it appears very important for the daily routine of the individuals, very few researchers have investigated distribution through the 24-h cycle. In a preliminary report, we described a preferential incidence of this behavior 2 h before nocturnal rest in families of common marmosets. We expand the data using 8 family groups (28 subjects), 8 fathers, 6 mothers, 8 nonreproductive adults (4 sons and 4 daughters), and 6 juvenile (3 sons and 3 daughters) offspring that we kept in outdoor cages under natural environmental conditions. We recorded the frequency of anogenital scent marking for each group during the light phase, twice a wk, for 4 consecutive wks, from March 1998 to September 1999. Cosinor test detected 24- and 8-h variations in 89.3% and 85.7% of the subjects, respectively, regardless of sex or reproductive status. The 8-h component is a consequence of the 2 peaks for the behavior, at the beginning and end of the light phase. Daily distribution of scent marking is similar to that others described previously for motor activity in marmosets. The coincident rhythmical patterns for both behaviors seem to be associated with feeding behavior, as described for callitrichids in free-ranging conditions, involving an increase in foraging activities early in the morning and shortly before nocturnal rest

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Scent-marking behavior is associated with different behavioral contexts in callitrichids, including signalizing a territory, location of feeding resources, and social rank. In marmosets and tamarins it is also associated with intersexual communication. Though it appears very important for the daily routine of the individuals, very few researchers have investigated distribution through the 24-h cycle. In a preliminary report, we described a preferential incidence of this behavior 2 h before nocturnal rest in families of common marmosets. We expand the data using 8 family groups (28 subjects), 8 fathers, 6 mothers, 8 nonreproductive adults (4 sons and 4 daughters), and 6 juvenile (3 sons and 3 daughters) offspring that we kept in outdoor cages under natural environmental conditions. We recorded the frequency of anogenital scent marking for each group during the light phase, twice a wk, for 4 consecutive wks, from March 1998 to September 1999. Cosinor test detected 24- and 8-h variations in 89.3% and 85.7% of the subjects, respectively, regardless of sex or reproductive status. The 8-h component is a consequence of the 2 peaks for the behavior, at the beginning and end of the light phase. Daily distribution of scent marking is similar to that others described previously for motor activity in marmosets. The coincident rhythmical patterns for both behaviors seem to be associated with feeding behavior, as described for callitrichids in free-ranging conditions, involving an increase in foraging activities early in the morning and shortly before nocturnal rest

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This chapter explores the relationship between environmental conflicts and technical progress, trying to understand, in the case of large mines of the Iberian Pyrite Belt, in Alentejo, how emerging environmental problems conditioned the performance or led to the search for alternative technical solutions, taking as chronological limit for this observation the beginning of World War II. In the absence of the archives of the companies, the research was based on existing administrative documents in the state archives (mining engineers reports, the licensing of mining activities), on reports and documents published in specialized mining press, in particular, the Bulletin of the Ministry of Public Works, Trade and Industry, the Journal of Public Works, Trade and Industry (both in Portuguese), and finally in the local press. Despite that limitation, the information available shows that in global competition markets, the success of the British enterprise in Santo Domingo had the active search for new technical solutions for the creation and adaptation of existing knowledge to local problems in order to maximize the mineral resources available. The early development of the hydrometallurgical processes for the treatment of poor ores, named ‘natural cementation’, can be explained as the way these companies tried to solve problems of competitiveness, boosting economies of scale. Thus, they transferred the environmental costs previously limited to agriculture to more fragile social groups, the poor fishermen of Guadiana River and of Vila Real de Santo António. Therefore, the hydrometallurgy of pyrites was developed locally, pioneered in Santo Domingo that allowed the survival and expansion of the British company from the late 1870s, that is, at a time when most small mines shut since they were not able to compete globally. Through different consented and regulated processes (judicial), through conflict or parliamentary mediation, the State imposed exceptionally additional costs to companies, either for compensation, the imposing the application of remediation measures to reduce the environmental damage in some cases, thus contributing to derail some projects. These cases suggest that the interaction between local conflicts, corporate behavior and technological progress proves to be complex. This article aims to contribute to the debate on economic and social history between the environment and technological progress, arguing that the fixed costs and economic imponderable social risks were factors that encouraged the companies to search for new solutions and to introduce innovations since that would allow the expansion of their activity. In this process the companies sometimes faced environmental dilemmas and unforeseen costs with consequences on the economy of firms. The nature of the knowledge needed to address the environmental problems they created, however, is of a very different nature from that knowledge needed to face the environmental burdens that were inherent to the development of its activity.

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A Intervenção Precoce é uma área científica que evidencia uma evolução muito significativa em poucos anos. A mudança de paradigma – do modelo centrado na criança para o modelo centrado na família – implica novos contextos e formas de prestação de serviços, sendo prática recomendada na atualidade – a intervenção em contextos naturais. Este trabalho surge assim com o objetivo de realizar uma revisão da literatura sobre esta temática: Intervenção Precoce em contextos naturais. Pretendeu-se discutir o conceito e a sua importância no panorama atual, diversos instrumentos, modelos e propostas de intervenção, bem como resultados de investigações conduzidas a nível internacional e nacional. No seio dos contextos naturais surge um conceito ainda mais específico designado como rotinas, merecendo papel de destaque pela sua relevância, num trabalho de base ecológica. Aprofundamos mais especificamente, o tema das rotinas em contexto familiar e das rotinas em contexto educativo pois o contexto educativo e domiciliário são dos contextos naturais mais referidos na literatura em crianças entre os 0 e os 6 anos de idade. A literatura científica demonstrou, de forma clara, que as rotinas que acontecem nos contextos naturais da criança são mais eficazes para apoiar e sustentar o trabalho em intervenção precoce. Concluímos ainda que é uma área que carece de investigação, tanto em termos internacionais como nacionais, estando, o nosso país mais focado no desenvolvimento e investigação de intervenções baseadas nas rotinas em contexto domiciliário do que em contexto educativo.

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O presente documento, criado no âmbito da Unidade Curricular de Atividade de Aprofundamento de Competências Profissionais, do Mestrado em Reabilitação Psicomotora, apresenta o trabalho desenvolvido no Centro de Reabilitação Psicossocial, das Irmãs Hospitaleiras em Maputo – Moçambique. O processo de intervenção psicomotora foi desenvolvido com jovens/adultos com Dificuldades Intelectuais e Desenvolvimentais e crianças com Paralisia Cerebral ou Atraso Global do Desenvolvimento, durante 8 meses. A intervenção concretizou-se em sessões de grupo e individuais em contexto de atividade motora, terapias expressivas, desenvolvimento pessoal e social com os jovens/adultos e em contexto de promoção do desenvolvimento psicomotor, atividades psicopedagógicas e terapias expressivas com as crianças, com objetivo de promoção de bem-estar, qualidade de vida, funcionalidade e autonomia dos utentes, tendo em conta o contexto cultural, familiar e as potencialidades, dificuldades e interesses. No processo de intervenção estiveram presentes as fases próprias da prática terapêutica, observação, conhecimento e criação de relação empática com os utentes, avaliação inicial, processo de intervenção planeado, avaliação final e comparação dos resultados com avaliação inicial e reflexão sobre o mesmo. É ainda apresentado um projeto de investigação centrado no estudo das atitudes da comunidade do Bairro das Mahotas perante a população com Dificuldade Intelectual e Desenvolvimental.

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The effects of serum and brain calcium concentration on rat behavior were tested by maintaining animals on either distilled water (N = 60) or water containing 1% calcium gluconate (N = 60) for 3 days. Animals that were maintained on high calcium drinking water presented increased serum calcium levels (control = 10.12 ± 0.46 vs calcium treated = 11.62 ± 0.51 µg/dl). Increase of brain calcium levels was not statistically significant. In the behavioral experiments each rat was used for only one test. Rats that were maintained on high calcium drinking water showed increased open-field behavior of ambulation (20.68%) and rearing (64.57%). on the hole-board, calcium-supplemented animals showed increased head-dip (67%) and head-dipping (126%), suggesting increased ambulatory and exploratory behavior. The time of social interaction was normal in animals maintained on drinking water containing added calcium. Rats supplemented with calcium and submitted to elevated plus-maze tests showed a normal status of anxiety and elevated locomotor activity. We conclude that elevated levels of calcium enhance motor and exploratory behavior of rats without inducing other behavioral alterations. These data suggest the need for a more detailed analysis of several current proposals for the use of calcium therapy in humans, for example in altered blood pressure states, bone mineral metabolism disorders in the elderly, hypocalcemic states, and athletic activities.

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Alterations to the supply of oxygen during early life presents a profound stressor to physiological systems with aberrant remodeling that is often long-lasting. Chronic intermittent hypoxia (CIH) is a feature of apnea of prematurity, chronic lung disease, and sleep apnea. CIH affects respiratory control but there is a dearth of information concerning the effects of CIH on respiratory muscles, including the diaphragm—the major pump muscle of breathing. We investigated the effects of exposure to gestational CIH (gCIH) and postnatal CIH (pCIH) on diaphragm muscle function in male and female rats. CIH consisted of exposure in environmental chambers to 90 s of hypoxia reaching 5% O2 at nadir, once every 5 min, 8 h a day. Exposure to gCIH started within 24 h of identification of a copulation plug and continued until day 20 of gestation; animals were studied on postnatal day 22 or 42. For pCIH, pups were born in normoxia and within 24 h of delivery were exposed with dams to CIH for 3 weeks; animals were studied on postnatal day 22 or 42. Sham groups were exposed to normoxia in parallel. Following gas exposures, diaphragm muscle contractile, and endurance properties were examined ex vivo. Neither gCIH nor pCIH exposure had effects on diaphragm muscle force-generating capacity or endurance in either sex. Similarly, early life exposure to CIH did not affect muscle tolerance of severe hypoxic stress determined ex vivo. The findings contrast with our recent observation of upper airway dilator muscle weakness following exposure to pCIH. Thus, the present study suggests a relative resilience to hypoxic stress in diaphragm muscle. Co-ordinated activity of thoracic pump and upper airway dilator muscles is required for optimal control of upper airway caliber. A mismatch in the force-generating capacity of the complementary muscle groups could have adverse consequences for the control of airway patency and respiratory homeostasis.

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La clase de educación física es un espacio en el cual los niños y adolescentes pueden incrementar los niveles de actividad física y alcanzar las recomendaciones emitidas por la Organización Mundial de la Salud (OMS), sin embargo, existe poca evidencia científica a nivel nacional sobre las actividades físicas que realizan los estudiantes dentro del ámbito escolar, específicamente dentro de las clases de educación física y sus relaciones con el contexto; es por esto que el objetivo de este estudio fue evaluar los niveles de actividad física de niños y adolescentes durante las clases de educación física en tres colegios oficiales de Bogotá, Colombia, por medio de la herramienta SOFIT. Estudio de diseño descriptivo y transversal realizado entre octubre de 2014 y mayo de 2015. Las observaciones se llevaron a cabo en tres colegios oficiales de la ciudad de Bogotá ubicados en las localidades de Tunjuelito y Ciudad Bolívar que aceptaron su participación en la investigación. Se obtuvo la aprobación para participar de 1361 estudiantes (682 niñas y 679 niños) de 5 a 17 años de los cuales 180 estudiantes (93 niños y 87 niñas) fueron seleccionados de manera aleatoria sistemática, siguiendo el protocolo SOFIT para observar su nivel de actividad física durante las clases de educación física. El 45,23% del tiempo de la clase de educación física los estudiantes mantuvieron un comportamiento sedentario; mientras que el 30.91% y el 23.86% del tiempo de la clase presentaron un nivel de actividad física moderada (AFM) y vigorosa (AFV) respectivamente. El nivel de actividad física moderada a vigorosa (AFMV), fue de 54,78% es decir, 35,27 minutos de la clase. Los docentes no promovieron la actividad física en un 56,47% del tiempo de la clase y se encontró que ningún docente promovió la actividad física fuera de la clase, es decir, alentando a sus estudiantes a que practicaran cualquier forma de actividad física en horas extraescolares. El contexto de la clase que más se desarrolló fue la condición física con un 35,66% del tiempo de la clase, seguido por los contextos de generalidades 24,83% y habilidades 23,84%. El contexto de la clase generalidades está asociada significativamente y de manera negativa (β=-0,32, p=0,006) con menor porcentaje de tiempo en AFM y AFV, las variables activas de SOFIT, lo que sugiere que las clases deben invertir menos tiempo en este contexto e incrementar el porcentaje de tiempo en los otros contextos como condición física y habilidades para aumentar la cantidad de minutos de AFMV en los estudiantes.

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Debido a la problemática del sedentarismo e inactividad física en edad escolar y sus implicaciones en la aparición de enfermedades crónicas no transmisibles, surge un interés por realizar análisis cualitativos que tengan en cuenta los contextos sociales en los que se da esta problemática, con el objetivo de conocer, desde los actores inmersos en las comunidades, cómo se está llevando a cabo y cómo se entiende la actividad física; por tanto, se planteó en esta investigación un diseño narrativo en el cual se indagó, por medio de entrevistas a profundidad, acerca de las representaciones sociales y prácticas de actividad física que desarrollan 9 docentes de educación física pertenecientes a 3 colegios distritales de la Unidad de Planeamiento Zonal Tibabuyes, en la localidad de Suba en Bogotá, Colombia. Resultados: Los docentes entienden la actividad física como todo tipo de movimiento humano, así mismo, se evidencia que las prácticas deportivas son las que predominan en el ámbito escolar. En relación con las condiciones sociales, se encontró que el aspecto familiar es un limitante para el desarrollo de las prácticas físicas del estudiante. Las políticas escolares y distritales le restan importancia a las clases de educación física en el currículo escolar y la inseguridad, debido al consumo de sustancias psicoactivas en el sector, deteriora los espacios deportivos y recreativos como parques y zonas verdes.

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Objetivo: Estimar la relación entre indicadores de desempeño muscular y estado nutricional con la velocidad/agilidad, en una muestra de escolares de instituciones educativas del Distrito de Bogotá, Colombia, perteneciente al estudio FUPRECOL. Materiales y Métodos: estudio transversal, en 2803 niños y 3952 niñas (58.5 %), entre 9 y 17 años de edad, pertenecientes a 24 instituciones educativas del sector oficial, en Bogotá, Colombia. La velocidad/agilidad se evaluó con la prueba de carrera de ida y vuelta 4x10 m y los indicadores de fuerza muscular fueron medidos por medio de fuerza prensil, salto longitudinal. Las asociaciones se estimaron por medio de regresión logística binaria. Resultados: el 74.6 % de las mujeres y el 68.6 % de los varones mostraron bajos niveles de velocidad/agilidad; en mujeres, el modelo de regresión logística binario se observa que aquellas que tener bajos niveles de velocidad/agilidad se asociaba con obesidad (OR 2.25 IC 95 % 1.53-3.11), sobrepeso (OR 1.43 IC 95 % 1.19-1.72), bajos niveles de salto longitudinal (OR 2.06 IC 95 % 1.73-2.44) y tener valores de fuerza prensi no saludable (OR 1.45 IC 95 % 1.25-1.88). En hombres, tener entre 9-12 años, (OR 1.89 IC 95% 1.53-2.53), padecer de sobrepeso (OR 2.11 IC 95% 1.63-2.74) u obesidad (OR 3.00 IC 95% 2.03-4.43), se asoció con bajos niveles de velocidad/agilidad. Conclusión: se encontró que un alto porcentaje de la muestra estudiada tiene bajos niveles de velocidad/agilidad; adicionalmente, se observó una fuerte relación entre los indicadores de adiposidad y desempeño muscular, con los niveles de velocidad/agilidad. Se sugiere la implementación de programas escolares, que contrarresten la aparición de manifestaciones de riesgo cardiometabólico.

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Com a presente investigação pretendeu-se validar a metodologia de análise retrospetiva de vídeos familiares e explorar potenciais sinais de risco precoce em crianças com SXF(N=6). Utilizando grelhas de observação de comportamentos, analisou-se a atenção social, a atenção partilhada, e o desenvolvimento sensório-motor, nas crianças com SXF, dos 0-30 meses. Validou-se a metodologia de análise de vídeos retrospetivos para a identificação de sinais de risco. Com base no estudo dos sinais de risco, sugere-se que as crianças com SXF têm preferência por estímulos não-sociais (e.g., fixação visual prolongada em objetos), têm dificuldades em dirigir a atenção para estímulos sociais (e.g., chamada e resposta ao nome) e défices na atenção partilhada, e demonstram uma interação prolongada e repetitiva com objetos e as expressões afetivas positivas. Verificou-se também que as crianças com SXF parecem conseguir discriminar entre estímulos sociais e não-sociais (e.g., vocalização para as pessoas) e apresentam estereotipias em todas as idades; Identifying early risk features in children with FXS through home movies Abstract: This research aims to validade the retrospective video analysis methodology of home movies and to explore potential early risk signs in children with FXS (N=6). Recurring to an observational grids of behaviors, social attention, joint attention, social attention and sensorymotor features were analysed, in children with FXS, at 0-30 months. Retrospective video analysis was validated for the identification of early risk signs. The study of early risk signs suggests that infants with FXS prefer non-social stimuli (e.g., visual fixation in objects), have difficulties directing attention toward social stimuli (e.g., name prompts) and impairments in joint attention, prolongued and repetitive interaction with objects, and have positive affective rating. Findings reveal that infants with FXS seem to be able to discriminate from social and non-social stimuli (e.g., vocalizing to people) and presente stereotypies through all ages.

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Recognition of everyday human activity through mobile personal sensing technology plays a central role in the field of pervasive healthcare. The Bologna-based American company eSteps Inc. addresses the growing motor disability of the lower limbs by offering pre-, during and post-hospitalisation monitoring solutions with biomechanics and telerehabilitation protocol. It has developed a smart, customised and sustainable device to monitor motor activity, fatigue and injury risk for patients and a special app to share data with caregivers and medical specialists. The objective of this study is the development of an Artificial Intelligence model to recognize the activity performed by a person with Multiple Sclerosis or a healthy person through eSteps devices.

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Previous research has shown that crotamine, a toxin isolated from the venom of Crotalus durissus terrificus, induces the release of acetylcholine and dopamine in the central nervous system of rats. Particularly, these neurotransmitters are important modulators of memory processes. Therefore, in this study we investigated the effects of crotamine infusion on persistence of memory in rats. We verified that the intrahippocampal infusion of crotamine (1 μg/μl; 1 μl/side) improved the persistence of object recognition and aversive memory. By other side, the intrahippocampal infusion of the toxin did not alter locomotor and exploratory activities, anxiety or pain threshold. These results demonstrate a future prospect of using crotamine as potential pharmacological tool to treat diseases involving memory impairment, although it is still necessary more researches to better elucidate the crotamine effects on hippocampus and memory.

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The practice of physical activities contributes to reducing the risk of chronic diseases and improves sleep patterns in the elderly. This research aimed to investigate the association between insomnia symptoms and daytime nap and the participation in physical leisure activities in elderly community residents. Data from the Studies Network of the Fragility in Brazilian Elderly (Campinas site), were used. Information from 689 elderly was analyzed, regarding sociodemographic characterization, physical leisure activity, occurrence of daytime napping and its duration, symptoms of insomnia and use of sleep medication. A significant association was found between the practice of walking and the daytime nap of short duration. Studies indicate that a short nap can benefit the quality of sleep and health of the elderly. Therefore, promoting the practice of walking can be a nursing intervention that favors the sleep patterns of the elderly.