113 resultados para objektiv kontroll


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Territoriality is a central issue in indigenous peoples struggles. The territorial struggles involve struggles over the control of natural resources and over political participation and representation, but also over the perception of territorial rights and the symbolic representation of the territory. These struggles are carried through both in material and symbolic ways through recurring to different discourses and representations that provide legitimation for the territorial claims of the group. The study is located in the Northern Autonomous Atlantic Region of Nicaragua. The study concerns the territorial strategies, conceptions and practices of the indigenous people and other actors. Territorial conflicts exist between the autonomous region and the central government of Nicaragua, between mestizo settlers and indigenous people, between different indigenous groups, and between these and development agents such as conservation projects. The study focuses on how territorial discourses and representations are used to legitimate territorial control. Environmental, historical and cartographical discourses are the most important discourses recurred to. The influence of discourses and representations on the territorial practices and policies of the different actors, the links between the local struggles and global processes, and the broader structural factors impacting on the territorial struggles are also analysed. Among the structural factors are the problems related to land tenure and management and the use of natural resources, the advance of the agricultural frontier, the institutional weaknesses of the central and regional governments and the legislative processes. The territorial discourses are both recurred to in a strategic way and also grounded in local ideals and practices. The discourses have produced real effects for example in legislation, land tenure systems, political representation and environmental practices. Although the use of discourses and representations are an important power tool in territorial struggles, territorial control cannot be effectively accomplished merely through representing territorial claims in a legitimate way or through reforming legislation, as the conflicts are also largely a result of structural factors affecting the region. The fieldwork was carried out during a total of twelve months between 2000 and 2002. The research methods used were semi-structured interviews, participant observation and participatory research methods. A broad range of literary sources were also used to collect data. The study is located within the field of critical political geography with a discursive political ecology approach. It can be called a critical realist approach to the discursive analysis of indigenous territoriality.

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Plus-stranded (plus) RNA viruses multiply within a cellular environment as tightly integrated units and rely on the genetic information carried within their genomes for multiplication and, hence, persistence. The minimal genomes of plus RNA viruses are unable to encode the molecular machineries that are required for virus multiplication. This sets requisites for the virus, which must form compatible interactions with host components during multiplication to successfully utilize primary metabolites as building blocks or metabolic energy, and to divert the protein synthesis machinery for production of viral proteins. In fact, the emerging picture of a virus-infected cell displays tight integration with the virus, from simple host and virus protein interactions through to major changes in the physiological state of the host cell. This study set out to develop a method for the identification of host components, mainly host proteins, that interact with proteins of Potato virus A (PVA; Potyvirus) during infection. This goal was approached by developing affinity-tag based methods for the purification of viral proteins complexed with associated host proteins from infected plants. Using this method, host membrane-associated viral ribonucleoprotein (RNP) complexes were obtained, and several host and viral proteins could be identified as components of these complexes. One of the host proteins identified using this strategy was a member of the heat shock protein 70 (HSP70) family, and this protein was chosen for further analysis. To enable the analysis of viral gene expression, a second method was developed based on Agrobacterium-mediated virus genome delivery into plant cells, and detection of virally expressed Renilla luciferase (RLUC) as a quantitative measure of viral gene expression. Using this method, it was observed that down-regulation of HSP70 caused a PVA coat protein (CP)-mediated defect associated with replication. Further experimentation suggested that CP can inhibit viral gene expression and that a distinct translational activity coupled to replication, referred to as replication-associated translation (RAT), exists. Unlike translation of replication-deficient viral RNA, RAT was dependent on HSP70 and its co-chaperone CPIP. HSP70 and CPIP together regulated CP turnover by promoting its modification by ubiquitin. Based on these results, an HSP70 and CPIP-driven mechanism that functions to regulate CP during viral RNA replication and/or translation is proposed, possibly to prevent premature particle assembly caused by CP association with viral RNA.

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Background. Patients with type 1 diabetes are at markedly increased risk of vascular complications. In this respect it is noteworthy that hyperglycaemia that is shown to cause endothelial dysfunction, has clearly been shown to be a risk factor for diabetic microvascular disease. However, the role of hyperglycaemia as a predictor of macrovascular disease is not as clear as for microvascular disease, although type 1 diabetes itself increases the risk of cardiovascular disease substantially. Furthermore, it is not known whether it is the short-term or the long-term hyperglycaemia that confers possible risk. In addition, the role of glucose variability as a predictor of complications is to a large extent unexplored. Interestingly, although hyperglycaemia increases the risk of pre-eclampsia in women with type 1 diabetes, it is unclear whether pre-eclampsia, a condition characterized by endothelial dysfunction, is also a risk factor for microvascular complication, diabetic nephropathy. Aims. This doctoral thesis investigated the role of acute hyperglycaemia and glucose variability on arterial stiffness and cardiac ventricular repolarisation in male patients with type 1 diabetes as well as in healthy male volunteers. The thesis also explored whether acute hyperglycaemia leads to an inflammatory response, endothelial dysfunction and oxidative stress. Finally, the role of pre-eclampsia, as a predictor of diabetic nephropathy in type 1 diabetes was examined. Subjects and methods. In order to study glucose variability and the daily glycaemic control, 22 male patients with type 1 diabetes, without any diabetic complications, were monitored for 72-h with a continuous glucose monitoring system. At the end of the 72-h glucose monitoring period a 2-h hyperglycaemic clamp was performed both in the patients with type 1 diabetes and in the 13 healthy age-matched male volunteers. Blood pressure, arterial stiffness and QT time were measured to detect vascular changes during acute hyperglycaemia. Blood samples were drawn at baseline (normoglycaemia) and during acute hyperglycaemia. In another patient sample, women with type 1 diabetes were followed during their pregnancy and restudied eleven years later to elucidate the role of pre-eclampsia and pregnancy-induced hypertension as potential risk factors for diabetic nephropathy. Results and conclusions. Acute hyperglycaemia increased arterial stiffness as well as caused a disturbance in the myocardial ventricular repolarisation, emphasizing the importance of a strict daily glycaemic control in male patients with type 1 diabetes. An inflammatory response was also observed during acute hyperglycaemia. Furthermore, a high mean daily blood glucose but not glucose variability per se is associated with arterial stiffness. While glucose variability in turn correlated with central blood pressure, the results suggest that the glucose metabolism is closely linked to the haemodynamic changes in male patients with uncomplicated type 1 diabetes. Notably, the results are not directly applicable to females. Finally, a history of a pre-eclamptic pregnancy, but not pregnancy-induced hypertension was associated with increased risk of diabetic nephropathy.

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Controlled nuclear fusion is one of the most promising sources of energy for the future. Before this goal can be achieved, one must be able to control the enormous energy densities which are present in the core plasma in a fusion reactor. In order to be able to predict the evolution and thereby the lifetime of different plasma facing materials under reactor-relevant conditions, the interaction of atoms and molecules with plasma first wall surfaces have to be studied in detail. In this thesis, the fundamental sticking and erosion processes of carbon-based materials, the nature of hydrocarbon species released from plasma-facing surfaces, and the evolution of the components under cumulative bombardment by atoms and molecules have been investigated by means of molecular dynamics simulations using both analytic potentials and a semi-empirical tight-binding method. The sticking cross-section of CH3 radicals at unsaturated carbon sites at diamond (111) surfaces is observed to decrease with increasing angle of incidence, a dependence which can be described by a simple geometrical model. The simulations furthermore show the sticking cross-section of CH3 radicals to be strongly dependent on the local neighborhood of the unsaturated carbon site. The erosion of amorphous hydrogenated carbon surfaces by helium, neon, and argon ions in combination with hydrogen at energies ranging from 2 to 10 eV is studied using both non-cumulative and cumulative bombardment simulations. The results show no significant differences between sputtering yields obtained from bombardment simulations with different noble gas ions. The final simulation cells from the 5 and 10 eV ion bombardment simulations, however, show marked differences in surface morphology. In further simulations the behavior of amorphous hydrogenated carbon surfaces under bombardment with D^+, D^+2, and D^+3 ions in the energy range from 2 to 30 eV has been investigated. The total chemical sputtering yields indicate that molecular projectiles lead to larger sputtering yields than atomic projectiles. Finally, the effect of hydrogen ion bombardment of both crystalline and amorphous tungsten carbide surfaces is studied. Prolonged bombardment is found to lead to the formation of an amorphous tungsten carbide layer, regardless of the initial structure of the sample. In agreement with experiment, preferential sputtering of carbon is observed in both the cumulative and non-cumulative simulations

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This is an ethnographic study, in the field of medical anthropology, of village life among farmers in southwest Finland. It is based on 12 months of field work conducted 2002-2003 in a coastal village. The study discusses how social and cultural change affects the life of farmers, how they experience it and how they act in order to deal with the it. Using social suffering as a methodological approach the study seeks to investigate how change is related to lived experiences, idioms of distress, and narratives. Its aim has been to draw a locally specific picture of what matters are at stake in the local moral world that these farmers inhabit, and how they emerge as creative actors within it. A central assumption made about change is that it is two-fold; both a constructive force which gives birth to something new, and also a process that brings about uncertainty regarding the future. Uncertainty is understood as an existential condition of human life that demands a response, both causing suffering and transforming it. The possibility for positive outcomes in the future enables one to understand this small suffering of everyday life both as a consequence of social change, which fragments and destroys, and as an answer to it - as something that is positively meaningful. Suffering is seen to engage individuals to ensure continuity, in spite of the odds, and to sustain hope regarding the future. When the fieldwork was initiated Finland had been a member of the European Union for seven years and farmers felt it had substantially impacted on their working conditions. They complained about the restrictions placed on their autonomy and that their knowledge was neither recognised, nor respected by the bureaucrats of the EU system. New regulations require them to work in a manner that is morally unacceptable to them and financial insecurity has become more prominent. All these changes indicate the potential loss of the home and of the ability to ensure continuity of the family farm. Although the study initially focused on getting a general picture of working conditions and the nature of farming life, during the course of the fieldwork there was repeated mention of a perceived high prevalence of cancer in the area. This cancer talk is replete with metaphors that reveal cultural meanings tied to the farming life and the core values of autonomy, endurance and permanence. It also forms the basis of a shared identity and a means of delivering a moral message about the fragmentation of the good life; the loss of control; and the invasion of the foreign. This thesis formed part of the research project Expressions of Suffering. Ethnographies of Illness Experiences in Contemporary Finnish Contexts funded by the Academy of Finland. It opens up a vital perspective on the multiplicity and variety of the experience of suffering and that it is particularly through the use of the ethnographic method that these experiences can be brought to light. Keywords: suffering, uncertainty, phenomenology, habitus, agency, cancer, farming

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"Trust and Collectives" is a compilation of articles: (I) "On Rational Trust" (in Meggle, G. (ed.) Social Facts & Collective Intentionality, Dr. Hänsel-Hohenhausen AG (currently Ontos), 2002), (II) "Simulating Rational Social Normative Trust, Predictive Trust, and Predictive Reliance Between Agents" (M.Tuomela and S. Hofmann, Ethics and Information Technology 5, 2003), (III) "A Collective's Trust in a Collective's action" (Protosociology, 18-19, 2003), and (IV) "Cooperation and Trust in Group Contexts" (R. Tuomela and M.Tuomela, Mind and Society 4/1, 2005 ). The articles are tied together by an introduction that dwells deeply on the topic of trust. (I) presents a somewhat general version of (RSNTR) and some basic arguments. (II) offers an application of (RSNTR) for a computer simulation of trust.(III) applies (RSNTR) to Raimo Tuomela's "we-mode"collectives (i.e. The Philosophy of Social Practices, Cambridge University Press, 2002). (IV) analyzes cooperation and trust in the context of acting as a member of a collective. Thus, (IV) elaborates on the topic of collective agency in (III) and puts the trust account (RSNTR) to work in a framework of cooperation. The central aim of this work is to construct a well-argued conceptual and theoretical account of rational trust, viz. a person's subjectively rational trust in another person vis-à-vis his performance of an action, seen from a first-person point of view. The main method is conceptual and theoretical analysis understood along the lines of reflective equilibrium. The account of rational social normative trust (RSNTR), which is argued and defended against other views, is the result of the quest. The introduction stands on its own legs as an argued presentation of an analysis of the concept of rational trust and an analysis of trust itself (RSNTR). It is claimed that (RSNTR) is "genuine" trust and embedded in a relationship of mutual respect for the rights of the other party. This relationship is the growing site for trust, a causal and conceptual ground, but it is not taken as a reason for trusting (viz. predictive "trust"). Relevant themes such as risk, decision, rationality, control, and cooperation are discussed and the topics of the articles are briefly presented. In this work it is argued that genuine trust is to be kept apart from predictive "trust." When we trust a person vis-à-vis his future action that concerns ourselves on the basis of his personal traits and/or features of the specific situation we have a prediction-like attitude. Genuine trust develops in a relationship of mutual respect for the mutual rights of the other party. Such a relationship is formed through interaction where the parties gradually find harmony concerning "the rules of the game." The trust account stands as a contribution to philosophical research on central social notions and it could be used as a theoretical model in social psychology, economical and political science where interaction between persons and groups are in focus. The analysis could also serve as a model for a trust component in computer simulation of human action. In the context of everyday life the account clarifies the difference between predictive "trust" and genuine trust. There are no fast shortcuts to trust. Experiences of mutual respect for mutual rights cannot be had unless there is respect.

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I denna pro gradu avhandling undersöker jag Jokela-fallets diskursiva efterdyningar utgående från ett moralpanikperspektiv. Syftet är att se huruvida reaktionerna på och förklaringarna till skolmassakern i Jokela kan anses präglas av moralpanik, samt vilka andra förklaringsmodeller som präglade den omfattande Jokela-debatten. Avhandling grundar sig på en kvalitativ diskursanalys av förklaringsmodellerna så som de presenterades i opinionstexter och insändare i Helsingin Sanomat hösten 2007. Jag analyserar hur den medierade Jokela-debatten utvecklades och formade perceptionerna om skolskjutningar, ungdomar och det finländska samhällstillståndet i stort. Jokela-fallet väckte starka reaktioner och rädsla. Man försökte förstå och förklara orsakerna till skottdramat. Flera olika förklaringsmodeller presenterades i medierna; en oro över ungdomens mentala hälsa och mobbning, webbens och populärkulturens farliga inflytande, det hårdnade samhällsklimatet och en försvagad välfärd, också den bristfälliga vapenlagstiftningen kritiserades. Den gemensamma nämnaren var att Jokela-fallet uppfattades som en indikator på hela samhällets tillstånd där en gemensam värdegrund och moral håller på att erodera. Mitt teoretiska perspektiv grundar sig främst på moralpanikteorier av Stanley Cohen och Chas Critcher som jag kopplar ihop med Ulrich Becks teori om risksamhället och Emile Durkheims anomiteori. Det här speglar jag mot bland annat Hille Koskelas forskning om rädslans kultur och trygghetssamhället, samt jämför med amerikansk forskning om skolskjutningar. Jokela-debatten formades främst av två dominerande diskurser: a) en rationaliseringsdiskurs som kännetecknas av att man försöker förklara Jokela-fallet genom förnuftsmässiga och logiska resonemang genom att peka på olika samhällsaspekter, b) en risk- och kontrolldiskurs som kännetecknas av moralpaniktendenser främst i form av oro över ungdomar, internet och försvagade samhällsnormer, samt krav på ökad social kontroll och reglering för att säkra trygghet och ordning i samhället. Jokela-fallet var inte ett klassiskt moralpanikfall, men fyllde många av kriterierna för moralpanik. Jokela-debatten uttryckte en rädslans kultur som genomsyrar dagens risksamhälle och som legitimerar ökad riskhantering och social kontroll, som försvar mot de hot och problem som samhället kollektivt upplever. Det ställdes krav på mera social kontroll och reglering på grund av upplevda hot mot samhällets normer och en försvagad moral, vilket är ett uttryck för moralpanik. Jokela-fallets diskursiva efterdyningar visar att tryggheten har blivit ett moraliskt imperativ. Trygghet har blivit något vi förutsätts eftersträva och som vi är färdiga att betala ett allt högre pris för, både mätt i pengar och i frihet.

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Revisorn utför ekonomisk kontroll inom sitt uppdrag. Ett vållande av ekonomisk skada när revisorn utför uppdraget innebär att han kan åläggas skadeståndsansvar. På senare tid har revisors vållande vid ekonomisk kontroll prövats av de högsta rättsinstanserna i de nordiska länderna. De högsta rättsinstanserna tenderar att gå långt i sina bedömningar om revisors vållande av ekonomisk skada. De ställer ofta aktsamhetskravet högt då de ålägger revisorerna skadeståndsansvar. I avhandlingen testas revisors skadeståndsansvar enligt en i undersökningen uppbyggd ekonomisk modell. Målsättningen är att vållanderegeln skall leda till ekonomisk effektivitet. Ekonomisk effektivitet prövas genom att en ekonomisk avvägning mellan nyttan och kostnaden med att företa skadeförebyggande åtgärder görs. I den ekonomiska analysen beskrivs revisors vållande i termer av revisors bristande omsorg, medan revisors grova vållande beskrivs som uppenbar försummelse. För undersökningen utgör det nordiska rättsfallsmaterialet ett material där strukturen är likadan, vilket gör det möjligt att pröva ekonomisk effektivitet. Resultatet av den ekonomiska analysen visar att ersättning för förmögenhetsskador inte skall utgöra den egentliga målsättningen. För att kunna begränsa omfattningen av revisors ersättningsansvar så att det ur en samhällsekonomisk synvinkel är ekonomiskt effektivt, bör det formuleras en snäv bedömningsgrund för revisors bristande omsorg. Den ekonomiska analysen påvisar att revisorerna vid bristande omsorg bör åläggas ett administrativt ansvar i form av disciplinära åtgärder. Revisorer skall åläggas skadeståndsansvar endast vid uppenbar försummelse. Genom uppenbar försummelse underlåter revisorerna att förebygga uppenbar förutsebar skada och åsidosätter sitt professionsansvar på ett medvetet sätt.

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Föreliggande arbete är resultatet av ett experiment med en materialinsamlingsmetod. Vad händer om man lägger ut en enkät med frågor om språk på webben och låter den som vill leverera svar? Vilka är det som svarar och vad har respondentgruppens sammansättning för betydelse för resultatet, dvs. kan man lita på det och i vilken utsträckning i så fall? Kan en kvantitativ vinst, då många svarar, täcka en eventuell kvalitativ förlust, då man inte har kontroll över vilka de många är? Man anar att svarsmönstret med nödvändighet måste vara brokigt och strävar att täcka in så mycket av det som möjligt och då är webbalternativet värt att pröva på. Tanken att ta reda på vad språkbrukarna själva har för syn på sitt språk, och vad de har för synpunkter bl.a. på språkvården, var egentligen inte ny, men den hade fått ny aktualitet i samband med arbetet med Svenska språknämndens handlingsprogram för svenskan i Finland (Tänk om ... 2003). Webbenkäten är uppgjord så att den matchar en liknande undersökning som genomfördes som en traditionell postenkät 30 år tidigare. Webbenkäten gav många svar och respondenterna representerade många olika språkmiljöer. Det fanns fler likheter än olikheter mellan svaren i webbenkäten 2002 och i enkätundersökningen 1972. En skillnad som dock märktes var att respondenterna i dag inte uppfattar svenskan i Finland som ålderdomlig, utan snarare karaktäriserar den som finskpåverkad. En påfallande likhet var känslan för det mest finlandssvenska, nämligen de specifikt finlandssvenska orden och uttrycken samt inslagen av finlandssvensk dialekt.

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Forskningen utreder skillnader mellan finsk- och svenskspråkiga skolor i en kommun i Nylands län utgående från elevvårdens synvinkel. Syftet är att kartlägga situationen i en kommun och synliggöra de skillnader och faktorer som påverkar det sociala kapitalets mängd i skolorna. Skillnaderna betraktas utgående från det sociala kapitalets inverkan på gemenskapen och från ekologisk synvinkel. Sambandet mellan det sociala stöd och den sociala kontroll som särskilt de vuxna i skolan producerar, har betydelse för skolelevers välmående. För att kunna bilda en socialt stödande och socialt kontrollerande atmosfär krävs det funktionella förändringar i skolan. Särskilt de vuxna i skolan skulle behöva mera gemenskap. Elevvårdsarbetet och skolarbetet riktar sig främst mot elever i dag, fastän de vuxna skulle behöva stärka sina sociala förhållanden. Bris i uppkomsten av socialt stöd och kontroll beror främst på problem i samarbete och kommunikation mellan de vuxna i skolan. Skolkuratorerna är de enda professionella inom skolan som i sitt arbete tar hela skolan som gemenskap i beaktande. Denna forskning är en abduktiv kvalitativ fallstudie som är tili sin karaktär beskrivande. Som data används intervjuer av elevvärdspersonalen i kommunen och enkäten Hälsa i skolan av Institutet för hälsa och välfärd från år 2008. Viktigaste källan för forskningen är Noora Ellone (2008) forskning "Kasvuyhteisö nuoren turvana".

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Nybildning av blodkärl från tidigare existerande kärl, angiogenes, är ett väsentligt skede vid tumörtillväxt. Denna process regleras av bland annat tillväxtfaktorer, var av den vaskulära endoteliala tillväxtfaktorn har en central roll. Hämning av angiogenes kan ske antingen extracellulärt med hjälp av humaniserade monoklonala antikroppar eller intracellulärt med hjälp av småmolekylära hämmaren. Sunitinib är en småmolekylär multikinashämmare och inhiberar flera tyrosinkinasreceptorer som påverkar tumörtillväxten och metastasutvecklingen vid cancer. Sunitinibs främsta indikationer är gastrointestinala stromacellstumörer, metastaserad njurcellscancer och neuroendokrina tumörer i bukspottskörteln. Behandling med tyrosinkinashämmare orsakar biverkningar som hypertension, kardiotoxicitet och njursvikt, vilka antas bero på de hämmande effekterna på mål som inte är väsentliga för anti-cancer-aktiviteten (”off-target” biverkningar). Bland annat AMP-aktiverat proteinkinas (AMPK), ett kinas som upprätthåller metabolisk homeostas i hjärtat, inhiberas av sunitinib och antas framkalla kardiovaskulära biverkningar. För att reducera ”off-target” biverkningar strävar man till att hitta alternativ som minskar de skadliga effekterna utan att den terapeutiska aktiviteten försvagas. Bland annat ett begränsat kaloriintag har uppvisat skyddande effekt på hjärtat via mekanismer sammankopplade till ökad resistens mot oxidativ stress, inflammation och mitokondriell dysfunktion, samt avtagande apoptos och autofagi. Detta sker delvis genom aktivering av enzymet Sirt1. Syftet med den här studien var att undersöka ifall kaloribegränsning skyddar mot kardiovaskulära och renala biverkningar inducerade av sunitinib hos råttor. Dessutom studerades vilka signalkedjor i cellen som medverkar. I studien användes 40 spontant hypertensiva råttor samt 10 normotensiva Wistar-Kyoto råttor. Försöksdjuren delades in i fem grupper beroende på behandling; I WKY kontroll, II SHR kontroll, III SHR + kaloribegränsning 70 %, IV SHR + sunitinib 3 mg/kg och V SHR + sunitinib 3 mg/kg + kaloribegränsning 70 %. Behandlingsperioden var åtta veckor. Blodtrycket mättes varje vecka med svansmanchett, urinutsöndringen undersöktes vecka 4 och vecka 8 med metabolismburar, ultraljudsundersökning av hjärtat utfördes sista veckan och blodkärlens respons till acetylkolin och natriumnitroprussid studerades i samband med avlivning. Proteinerna Sirt1 och AMPK analyserades i hjärtat med Western blotting samt förekomsten av makrofagmarkören ED1 i njurarna med immunhistokemi. Studien visade att sunitinibdosen 3 mg/kg är mycket väl tolererbar hos råttor eftersom sunitinib inte orsakade högre blodtryck, kraftigare hypertrofi eller mer omfattande njurskada jämfört med obehandlade SHR- grupper. Utgående från resultaten kan man också konstatera att kaloribegränsningen har positiva kardiovaskulära effekter.

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Die Frauenbewegung vor 1918 war ein Bestandteil der emanzipativen Kräfte der Gesellschaft, die sich gegen die Ständegesellschaft richtete. Diese zerfiel im I. Weltkrieg und stürzte durch die Novemberrevolution von 1918. Die Gründung der Weimarer Republik brachte das allgemeine und gleiche Wahlrecht sowie gleiche Rechte und Pflichten für Männer und Frauen. Die zweite Welle der Frauenbewegung ab 1968 wurde zu einer Wiederholung der ersten, aber wegen schon bestehender Gleichberechtigung insgesamt als bloße Farce. Mit der dritten Welle der Frauenbewgung, beginnend mit der Weltfrauenkonferenz in Beijing (1995) setzte sich eine rein macht- und verteilungspolitisch inspirierte, ideologisch begründete Politik der Frauenprivilegierung mittels der Diskriminierung von Männern durch, die bisher ungebrochen ist. Eine solche Politik ist deshalb entgegen der subjektiven Selbstwahrnehmung objektiv eine rechte Politik, was aber von den Parteien der politischen Linken (im weitesten Sinne) verkannt wird.

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The utilization and management of arbuscular mycorrhiza (AM) symbiosis may improve production and sustainability of the cropping system. For this purpose, native AM fungi (AMF) were sought and tested for their efficiency to increase plant growth by enhanced P uptake and by alleviation of drought stress. Pot experiments with safflower (Carthamus tinctorius) and pea (Pisum sativum) in five soils (mostly sandy loamy Luvisols) and field experiments with peas were carried out during three years at four different sites. Host plants were grown in heated soils inoculated with AMF or the respective heat sterilized inoculum. In the case of peas, mutants resistant to AMF colonization were used as non-mycorrhizal controls. The mycorrhizal impact on yields and its components, transpiration, and P and N uptake was studied in several experiments, partly under varying P and N levels and water supply. Screening of native AMF by most probable number bioassays was not very meaningful. Soil monoliths were placed in the open to simulate field conditions. Inoculation with a native AMF mix improved grain yield, shoot and leaf growth variables as compared to control. Exposed to drought, higher soil water depletion of mycorrhizal plants resulted in a haying-off effect. The growth response to this inoculum could not be significantly reproduced in a subsequent open air pot experiment at two levels of irrigation and P fertilization, however, safflower grew better at higher P and water supply by multiples. The water use efficiency concerning biomass was improved by the AMF inoculum in the two experiments. Transpiration rates were not significantly affected by AM but as a tendency were higher in non-mycorrhizal safflower. A fundamental methodological problem in mycorrhiza field research is providing an appropriate (negative) control for the experimental factor arbuscular mycorrhiza. Soil sterilization or fungicide treatment have undesirable side effects in field and greenhouse settings. Furthermore, artificial rooting, temperature and light conditions in pot experiments may interfere with the interpretation of mycorrhiza effects. Therefore, the myc- pea mutant P2 was tested as a non-mycorrhizal control in a bioassay to evaluate AMF under field conditions in comparison to the symbiotic isogenetic wild type of var. FRISSON as a new integrative approach. However, mutant P2 is also of nod- phenotype and therefore unable to fix N2. A 3-factorial experiment was carried out in a climate chamber at high NPK fertilization to examine the two isolines under non-symbiotic and symbiotic conditions. P2 achieved the same (or higher) biomass as wild type both under good and poor water supply. However, inoculation with the AMF Glomus manihot did not improve plant growth. Differences of grain and straw yields in field trials were large (up to 80 per cent) between those isogenetic pea lines mainly due to higher P uptake under P and water limited conditions. The lacking N2 fixation in mutants was compensated for by high mineral N supply as indicated by the high N status of the pea mutant plants. This finding was corroborated by the results of a major field experiment at three sites with two levels of N fertilization. The higher N rate did not affect grain or straw yields of the non-fixing mutants. Very efficient AMF were detected in a Ferric Luvisol on pasture land as revealed by yield levels of the evaluation crop and by functional vital staining of highly colonized roots. Generally, levels of grain yield were low, at between 40 and 980 kg ha-1. An additional pot trial was carried out to elucidate the strong mycorrhizal effect in the Ferric Luvisol. A triplication of the plant equivalent field P fertilization was necessary to compensate for the mycorrhizal benefit which was with five times higher grain yield very similar to that found in the field experiment. However, the yield differences between the two isolines were not always plausible as the evaluation variable because they were also found in (small) field test trials with apparently sufficient P and N supply and in a soil of almost no AMF potential. This similarly occurred for pea lines of var. SPARKLE and its non-fixing mycorrhizal (E135) and non-symbiotic (R25) isomutants, which were tested in order to exclude experimentally undesirable benefits by N2 fixation. In contrast to var. FRISSON, SPARKLE was not a suitable variety for Mediterranean field conditions. This raises suspicion putative genetic defects other than symbiotic ones may be effective under field conditions, which would conflict with the concept of an appropriate control. It was concluded that AMF resistant plants may help to overcome fundamental problems of present research on arbuscular mycorrhiza, but may create new ones.

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Die Arbeit behandelt den Vorschlag für eine EU-Verordnung KOM/2000/7/final, 2000/0212(COD) des europäischen Parlaments und des Rates von der Kommission der Europäischen Gemeinschaften als Grundlage einer Marktöffnungsverordnung und welche Veränderungen sich dadurch in Deutschland einstellen werden. Ausschreibungen von Verkehrsleistungen werden zunehmen. Die Ausschreibungsarten werden sich in ländlichen Regionen von denen in Verkehrszentren unterscheiden. In der Region werden sich Bedarfslösungen stärker durchsetzen. Kürzungen von Verkehrsleistungen werden hier stärker ausfallen als in den Zentren und damit zu einem kleineren Leistungsvolumen führen. Aufgrund des geringen Leistungsumfangs gibt es weniger Interessenten. Bei Standardausschreibungen werden deshalb auch häufig die Varianten der beschränkten oder die freihändige Vergabe gewählt. Funktionale Ausschreibungen haben nur eine untergeordnete Bedeutung. In den Verkehrszentren sind die Lose größer und damit für viele Anbieter interessant. Die Verkehrszusatzleistungen sind zudem komplexer. Standardausschreibungen in öffentlicher Vergabeart werden sich hier vermutlich als Norm durchsetzen. Die VOL/A wird sicherlich ihre Bedeutung und ihren dafür notwendigen Regelungsumfang in Deutschland als deutsches oder als europäisches Recht behalten. Ob der empfehlende Charakter der DIN EN 13816 Norm „ÖPNV: Definition, Festlegung von Leistungszielen und Messung der Servicequalität“ erhalten werden kann und nicht als Steuerungselement zur Standardisierung im ÖPNV beitragen wird, ist dabei zu bezweifeln. Durch diese Wettbewerbspflicht wird der Aufgabenträger zum Besteller von Verkehrsleistungen. Damit geht die Verkehrsplanung in die Verantwortung des Aufgabenträgers über und gerät stärker in den Einflussbereich der Politik. Die strategisch abstrakte und die konkrete Verkehrsplanung wachsen für den Normfall der Standardausschreibung zusammen. Die Hoffnung auf eine bessere Netzintegration und eine Standardisierung des ÖPNV Angebots und der ÖPNV Qualität entsteht. Es entwickelt sich dadurch aber auch die Gefahr der Abhängigkeit des Nahverkehrsangebots von der derzeitigen Haushaltslage oder der Interessenlage der Politik. Kontinuität in Angebot und Qualität werden zu erklärten Planungszielen. Der Verkehrsplaner auf der Bestellerseite muss die Planung in Ausschreibungsunterlagen umsetzen. Dies erfordert erweiterte Kompetenzen in den Bereichen Betriebswirtschaft, Logistik, Jura, Informatik und Führungskompetenzen. Ausbildende Institutionen müssen darauf bereits im Vorfeld der Umsetzung reagieren. Durch die zeitliche Verzögerung der Umsetzung der Planung durch die Ausschreibungsschritte sind in der Verkehrsplanung längere Planungsvorlaufzeiten einzukalkulieren. Vorausschauender zu planen, wird dabei wichtiger. Auch eventuelle Fehler in der Planung sind nicht mehr so einfach zu korrigieren. Durch den gestiegenen Einsatz von Technologien in den Fahrzeugen besteht für den Verkehrsplaner dafür häufiger die Möglichkeit, Planungsänderungen auf ihre Wirksamkeit im Hinblick auf Attraktivität für den Fahrgast anhand von den ermittelten Fahrgastzahlen zu kontrollieren. Dasselbe gilt auch für Marketing- und Vertriebsmaßnahmen, wie für die Tarifpolitik. Die Zahlen stehen nicht nur für diese Rückkopplung zur Verfügung, sondern dienen auch als Planungsgrundlage für zukünftige Maßnahmen. Dem Planer stehen konkretere Zahlen für die Planung zur Verfügung. Ein Aspekt, der aufgrund der Sanktionsmaßnahmen bei Ausschreibungen an Bedeutung gewinnen wird, ist die Möglichkeit, Qualität von Verkehrsleistungen möglichst objektiv beurteilen zu können. Praxisrelevante Auswirkungen auf die Verkehrsplanung des öffentlichen Personennahverkehrs ergeben sich hauptsächlich durch die gestiegene Komplexität in der Planung selbst und den dadurch unverzichtbaren gewordenen Einsatz von Computerunterstützung. Die Umsetzung in Ausschreibungsunterlagen der Planung und die Kontrolle stellen neue Elemente im Aufgabenbereich des Verkehrsplaners dar und erfordern damit breiter ausgelegte Kernkompetenzen. Es werden mehr Verkehrsplaner mit breiterer Ausbildung benötigt werden. Diese Arbeit hat aufgezeigt, dass sich mit der Integration des Ausschreibungsgedankens in den Ablauf der Verkehrsplanung eine sprunghafte Entwicklung in der Planungstätigkeit ergeben wird. Aufgrund der in Zukunft steigenden Qualität und Quantität der Planungsgrundlagen und der ebenfalls gestiegenen Ansprüche an die Bewertungsparameter ergeben sich Veränderungen und neue Anforderungen auf diesem Gebiet, die in erster Linie für die Hochschulen und andere ausbildende Einrichtungen, aber auch für die Verkehrsplanung unterstützende Industrie.

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Jeder von uns weiß: Unterrichten kann sehr viel Freude machen, kann aber auch sehr belastend sein. Von welchen Faktoren hängt es ab, daß manchen KollegInnen selbst schwierige Bedingungen nichts auszumachen scheinen, während andere selbst geringfügige Störungen ihres Unterrichts als Belastung erleben? Untersuchungen über die Bewältigungsmuster von LehrerInnen zeigen, daß es keine objektiv gegebenen Belastungssituationen gibt: Wie wir Unterrichtssituationen erleben hängt in hohem Maß von unseren subjektiven Wahrnehmungsmustern bzw. unseren persönlichen Konstrukten ab.