High-speed electrooptical VOA integrated in silicon-on-insulator

In this paper, we present simulation results of an electrooptical variable optical attenuator (VOA) inte-grated in silicon-on-insulator waveguide. The device is functionally based on free carriers absorption toachieve attenuation. Beam propagation method (BPM) and two-dimensional semiconductor device simu-lation tool PISCES-Ⅱ were used to analyze the dc and transient characteristics of the device. The devicehas a response time (including rise time and fall time) less than 200 ns, much faster than the thermoopticand micro-electromechanical systems (MEMSs) based VOAs.

紧缩型SOI多模干涉光开关的设计

提出了一种新的紧缩型SOI多模干涉（MMI）光开关。开关由单模输入输出波导和MMI耦合器组成。通过在多模波导区域引入调制区，利用Si的等离子色散效应（PDE）改变调制区的折射率来实现开关动作。用FD-BPM方法对开关的工作原理和性能进行了模拟与分析。结果表明，光开尖良好的综合性能，而整个开关的长度只有7mm。

在解复用模块设计中有效折射率变化的研究

研究了基于SOI（silicon-on-insulator）材料的阵列波导光栅（AWG）分波器件，给出了此器件材料色散的数值拟合公式，进而利用BPM方法研究了材料色散脊型波导结构变化和器件制做中刻蚀深度误差对波导有效折射率和波分复用模块性能的影响。结果表明，刻蚀深度误差对模块性能优劣起关键作用。

SOI梯形截面光波导的模式分析

采用有效折射率和转移矩阵理论相结合的方法得到了SOI梯形光波导的本征模方程。计算得到的有效折射率与WKB法相比误差不超过10~(-5)，其垂直方向电场分布与BPM模拟结果基本相符。首次得到了SOI梯形波导的单模曲线和其近似解析表达式，此结果与修正的WKB法一致。

4 * 4区域调制多模干涉耦合器SOI光波导开关的设计

根据区域调制多模干涉耦合器光开关的工作原理，以2 * 2区域调制多模干涉光开关为基础，采用级联的方式设计了4 * 4区域调制多模干涉SOI光波导开关。用有限差分二维BPM方法模拟了器件在不同工作状态下的光场传输情况。器件工作波长为1.55 μm，在不计耦合损耗时器件的平均插入损耗小于2.0 dB/cm。

BPMN与BPEL双向转换系统的设计与实现及其应用

随着SOA和业务流程管理BPM技术日益成熟，基于业务流程的开发得到越来越广泛的应用。BPMN是由国际标准组织BPMI所制定的业务流程描述语言，制定了标准化的图形符号用于流程的设计和交流。WS-BPEL是面向服务计算中服务复合层重要的技术规范，WS-BPEL支持通过组合分布异构的服务形成复杂的业务流程。BPMN和BPEL模型之间存在差异，跨越两者之间的鸿沟实现无缝转换是当前服务计算中的关键问题之一。现有的BPMN到BPEL转换方法对用户建模限制太大，并且转换后的BPEL不能直接部署和运行，自动化程度不高。现有BPEL到BPMN转换方法缺少对复杂BPEL结构的转换。 针对这些问题，论文设计了一套双向模型转换方法。首先分析了现有BPMN到BPEL的转换方法。然后根据分析结果对已有的BPMN到BPEL转换方法进行扩展，并着重解决了路由OR和并发多实例Multi-instance的语义分析和转换这一难点问题，减少了用户建模时的限制，转换得到的可直接执行的BPEL，提高了自动化程度。在此基础上，设计了BPEL到BPMN的转换方法，采取自上而下的扁平化策略来将嵌套块结构的BPEL控制流转换成为平整无层次的流程图结构，其中分析了Link设置不同条件时的语义并分别转换到对应的BPMN结构，解决了复杂BPEL结构的转换。 最后，我们在流程设计平台OnceBPD（Once Business Process Designer）实现了双向转换功能，能够将BPMN模型转换为BPEL模型，得到的BPEL文件可以部署和运行在OnceBPEL流程执行引擎。还可以将BPEL模型装换为BPMN模型，并应用于OnceBPEL引擎监控信息的可视化，实现了在OnceBPD中直观、形象的显示流程监控。

HIRFL-CSR Tune值测量系统

兰州重离子加速器冷却储存环(HIRFL-CSR)工作点(Tune)测量系统已投入调束运行。采用FFT测量法,用白噪声信号做激励源,经功率放大并通过同轴开关切换将激励信号加载到垂直或水平的对称极板上,通过位置检测器(BPM)采集束流信号。将BPM两极板感应到的束流信号分别经前置放大器放大,再通过相位相差180°的合路器将差信号送入实时频谱仪进行傅里叶分析,从而计算出Tune值。本文主要介绍HIRFL-CSR工作点测量原理、系统构成以及测量结果。

基于领域的快速协同开发平台的研究与实践

在全面分析研究企业信息系统和大量实践的基础上,为解决传统企业信息系统开发存在的问题,提出并设计了一个企业级的基于领域的快速协同开发平台。通过对信息系统进行领域分析,得出了平台的总体架构,该平台采用了业务流程管理、模型驱动架构、面向服务架构等技术思想进行实现,并将这些思想有效结合,使其协同工作。通过具体的应用,验证了平台能有效地提高软件复用率,极大地缩短企业信息系统的开发周期,减少信息系统的成本支出。

SOME NEWER CONCEPTS OF ETHYLENE ALPHA-OLEFIN COPOLYMERIZATION ON HETEROGENEOUS ZIEGLER-NATTA CATALYSTS

Unsteady diffusion kinetic, recently advanced by this laboratory, is applied to the examination of some polymerization and molecular chain structure problems. Hitherto deemed "anomalous" phenomena, such as the faster rate of copolymerization of ethylene/alpha-olefin than the homopolymerization of ethylene and the enrichment in the incorporation of a higher alpha-olefin in its copolymerization with ethylene by a lower alpha-olefin, are reasonably explained by unsteady diffusion of monomers. Molecular chain structure of copolymers, such as compositional heterogeneity and its dependence on comonomer incorporation originates from the difference in diffusion coefficients of the monomers. A copolymer composition equation taking into consideration the unsteady diffusion was developed. In cases where simulated curves were compared with experimental curves, good agreements were found.

Studies On Benzo[A]Pyrene Mono-Oxygenase In The Shore Crab Carcinus-Maenas

A cytochrome P-450-dependent benzo[a]pyrene mono-oxygenase enzyme system (BPM) has been identified and partially characterized in males of the shore crab Carcinus maenas (L.). Apparent Km values obtained at 30 °C using microsomal preparations from the antennary glands of animals collected during summer were in the range 1.61–2.11 µM. The cytochrome P-450 content was 0·022 nmol/mg microsomal protein when BPM activity in the same preparation was 0·085 nmol/mg protein/min.

Tiflocolitis syndrome acute for "Klebsiella" sp. in a spanish pure breed horse. A case report

Were study a horse (Equus caballus), Purebred Spanish Horse, 6 years old, intact male sex, weight about 550kg, from equestrian center in Fregenal Sierra-Extremadura, Spain. History of acute diarrhea, are apply conventional treatment (hydration, anti-inflammatory and antibiotic). Physical examination showed severe profuse, fetid diarrhea deep red, tachypnea. The physiological parameters were: heart rate 60 bpm, respiratory rate 39 rpm and mucous cyanotic. Temperature: 40°C. Hematological examination showed severe leucopenia, decreased total serum protein, albumin and globulin also diminished. Serum chemistry evidenced severe hyponatremia and hypokalemia, with high levels of chlorine indicating metabolic acidosis. A stool analysis, which was negative and showed no eggs or larvae in the samples studied was performed. The microbial culture allowed the isolation of Klebsiella sp. and susceptibility testing showed sensitivity to ampicillin, Cetafzidine, Ciprofloxacin, Cefepine, gentamicin, imipenem, meropenem, Piperaciclina, piperacillin / tazobactam and trimethoprim sulfa resistance. The horse presented systemic complications associated with endotoxemia and death 36 hours after the onset of diarrhea. At necropsy, severe bleeding was observed enterotiflocolitis. The histological sections showed proliferative enteritis characterized by lymphocyte and mononuclear inflammatory infiltrate plasmocytorious mucosa and submucosa, coagulation necrosis, bacteria and short rod type morphology with no specific grouping. In conclusion a case of acute syndrome enterotiflocolitis reported Klebsiella sp. on a horse Purebred Spanish.

The health profile of football/soccer players in Northern Ireland - a review of the uefa pre-participation medical screening procedure.

BACKGROUND:
It is compulsory that domestic football/soccer teams in UEFA competitions organise players' pre-participation medicals. Although screening guidelines have been established, these remain controversial. The findings of medical examinations can have lasting consequences for athletes and doctors. No previous studies have reported UEFA pre-participation screening results in semi-professional footballers. This study aims to further knowledge regarding 'normal' data in this population.

METHOD:
Retrospective audit and analysis of records of pre-season medicals for all male first-team players at one semi-professional Northern Ireland Premiership team between 2009-2012. Medicals were conducted by the club doctor following the UEFA proforma. Height, weight, blood pressure (BP), full blood count (FBC), dipstick urinalysis and resting electrocardiogram (ECG) were conducted by an independent nurse. Only one ECG must be documented during a player's career; other tests are repeated yearly.

RESULTS:
89 medicals from 47 players (6 goalkeepers, 11 defenders, 22 midfielders and 8 attackers; mean age 25.0 years (SD 4.86)) were reviewed. Mean height of the players was 179.3 cm (SD 5.90) with a mean weight of 77.6 kg (SD 10.5). Of 89 urine dipsticks, 7 were positive for protein; all 7 were normal on repeat testing following 48 hours of rest. Of 40 ECGs (mean ventricular rate 61.2 bpm (SD 11.6)), one was referred to cardiology (right bundle branch block; prolonged Q-T interval). No players were excluded from participation.

CONCLUSIONS:
This study provides important information about 'normal' values in a population of semi-professional footballers. Urinalysis showing protein is not uncommon but is likely to be normal on repeat testing.

A mudança na administração pública:implementação de solução de atendimento CRM e nova gestão de processos – Estudo de Caso Município de Santarém

Dissertação, Mestrado, Gestão Pública, Instituto Politécnico de Santarém, Escola Superior de Gestão e Tecnologia, 2015

Design de compostos oxometálicos e estudo das suas propriedades catalíticas em reações de oxidação

A presente dissertação tem como objetivo principal contribuir para um maior conhecimento e compreensão das propriedades catalíticas de sistemas baseados em metais de transição com estado de oxidação elevado. O trabalho desenvolvido englobou a síntese e a caracterização de novos compostos de molibdénio, tendo como ponto de partida a síntese de cis-dioxocomplexos do tipo MoO2Cl2Ln (n = 1 ou 2, conforme ligandos bidentados ou monodentados, respetivamente) a partir dos precursores MoO2Cl2, MoO3 e Na2MoO4 com ligandos como dimetilformamida (DMF), tris(benzimidazolil)metano (HC(bim)3). Os compostos MoO2Cl2(DMF)2 (Capítulo2) e [MoO2Cl(HC(bim)3]Y (Y = Cl, BF4 e PF6) (Capítulo 3) foram testados como precursores catalíticos na epoxidação de olefinas, em fase heterogénea. O primeiro foi imobilizado no suporte MCM-41 enquanto os últimos foram heterogeneizados com recurso a líquidos iónicos - [BMIM]Y e [BMPy]Y (BIM = 1-n-butil-3-metilimidazólio, BMPy = 1-n-butil-3-metilpiridina; Y = BF4 ou PF6), como estratégia alternativa à heterogeneização dos catalisadores homogéneos. Por outro lado, aprofundou-se também a epoxidação de olefinas em fase homogénea e, para isso, sintetizaram-se os compostos Mo(CO)3(HC(pz)3) (HC(pz)3 = tris(1-pirazoli)metano), Mo(CO)3(HC(3,5-Me2pz)3 (HC(3,5-Me2pz)3 = tris(3,5-dimetil-1-pirazolil)metano) (Capítulo 4) e Mo(CO)4(BPM) (BPM = bis(pirazolil)metano) (Capítulo 5) a partir do material de partida Mo(CO)6. A descarbonilação oxidativa destes compostos, com TBHP, originaram estruturas cristalinas do tipo dioxo--oxo, [{MoO2(HC(pz)3)}2(2-O)][Mo6O19] e [{MoO2(HC(3,5-Me2pz)3)}2(2-O)][Mo6O19], e oxodiperoxo, MoO(O2)2(BPM), respetivamente. Obtiveram-se os mesmos produtos in situ durante as respetivas reações catalíticas. Todos os compostos foram utilizados como catalisadores ou pré-catalisadores na epoxidação de olefinas, com bons resultados. Por fim e, tendo em conta o crescente interesse em materiais híbridos orgânicos-inorgânicos baseados em óxidos de molibdénio, sintetizou-se o composto MoO2Cl2(pypzEA) (pypzEA = etil[(3-piridin-2-il)-1H-pirazol-1-il]acetato) o qual, ao reagir com água, originou o material híbrido [Mo2O6(HpypzA)] (HpypzA = [3-(piridin-2-il)-1H-pirazol-1-il]acetato) (Capítulo 6). A estrutura deste último composto foi resolvida por difração de monocristal e de raio-X de pós, em conjunto com a informação proveniente de técnicas como FT-IR, RMN 13C CP/MAS e análise elementar. Este material híbrido apresenta um bom desempenho catalítico quando o TBHP é usado como oxidante e continua estável e a comportar-se como um catalisador heterogéneo mesmo após sofrer testes de reciclagem e de filtração. Ainda durante este estudo constatou-se que a reação oxidativa do material de partida, MoO2Cl2(pypzEA), com TBHP, originou o oxo(diperoxo)complexo MoO(O2)2(pypzEA) e o complexo octamérico [Mo8O24(pypzEA)4] obtido previamente pela descarbonilação oxidativa do Mo(CO)4(pypzEA). Todos os catalisadores ou precursores de espécies ativas foram analisados por técnicas de caracterização comuns (AE, FT-IR, Raman, ATR, 1H RMN) bem como por técnicas de caracterização do estado sólido (EXAFS, DRX de pós e de cristal único, 13C e 29Si RMN CP MAS). Os compostos com propriedades catalíticas e pré-catalíticas promissoras foram estudados nas reações catalíticas de epoxidação de diversas olefinas, nomeadamente, cis-cicloocteno, 1-octeno, trans-2-octeno, -pineno, (R)-(+)-limoneno, estireno, norborneno, entre outras.

Business Process Modelling based on formal temporal theory with an application to hospital patient flows

Existing Workflow Management Systems (WFMSs) follow a pragmatic approach. They often use a proprietary modelling language with an intuitive graphical layout. However the underlying semantics lack a formal foundation. As a consequence, analysis issues, such as proving correctness i.e. soundness and completeness, and reliable execution are not supported at design level. This project will be using an applied ontology approach by formally defining key terms such as process, sub-process, action/task based on formal temporal theory. Current business process modelling (BPM) standards such as Business Process Modelling Notation (BPMN) and Unified Modelling Language (UML) Activity Diagram (AD) model their constructs with no logical basis. This investigation will contribute to the research and industry by providing a framework that will provide grounding for BPM to reason and represent a correct business process (BP). This is missing in the current BPM domain, and may result in reduction of the design costs and avert the burden of redundant terms used by the current standards. A graphical tool will be introduced which will implement the formal ontology defined in the framework. This new tool can be used both as a modelling tool and at the same time will serve the purpose of validating the model. This research will also fill the existing gap by providing a unified graphical representation to represent a BP in a logically consistent manner for the mainstream modelling standards in the fields of business and IT. A case study will be conducted to analyse a catalogue of existing ‘patient pathways’ i.e. processes, of King’s College Hospital NHS Trust including current performance statistics. Following the application of the framework, a mapping will be conducted, and new performance statistics will be collected. A cost/benefits analysis report will be produced comparing the results of the two approaches.