12 resultados para Stop codon

em Universidade do Minho


Relevância:

10.00% 10.00%

Publicador:

Resumo:

Electric Vehicles (EVs) have limited energy storage capacity and the maximum autonomy range is strongly dependent of the driver's behaviour. Due to the fact of that batteries cannot be recharged quickly during a journey, it is essential that a precise range prediction is available to the driver of the EV. With this information, it is possible to check if the desirable destination is achievable without a stop to charge the batteries, or even, if to reach the destination it is necessary to perform an optimized driving (e.g., cutting the air-conditioning, among others EV parameters). The outcome of this research work is the development of an Electric Vehicle Assistant (EVA). This is an application for mobile devices that will help users to take efficient decisions about route planning, charging management and energy efficiency. Therefore, it will contribute to foster EVs adoption as a new paradigm in the transportation sector.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Introduction of technologies in the workplace have led to a dramatic change. These changes have come with an increased capacity to gather data about one’s working performance (i.e. productivity), as well as the capacity to track one’s personal responses (i.e. emotional, physiological, etc.) to this changing workplace environment. This movement of self-monitoring or self-sensing using diverse types of wearable sensors combined with the use of computing has been identified as the Quantified-Self. Miniaturization of sensors, reduction in cost and a non-stop increase in the computer power capacity has led to a panacea of wearables and sensors to track and analyze all types of information. Utilized in the personal sphere to track information, a looming question remains, should employers use the information from the Quantified-Self to track their employees’ performance or well-being in the workplace and will this benefit employees? The aim of the present work is to layout the implications and challenges associated with the use of Quantified-Self information in the workplace. The Quantified-Self movement has enabled people to understand their personal life better by tracking multiple information and signals; such an approach could allow companies to gather knowledge on what drives productivity for their business and/or well-being of their employees. A discussion about the implications of this approach will cover 1) Monitoring health and well-being, 2) Oversight and safety, and 3) Mentoring and training. Challenges will address the question of 1) Privacy and Acceptability, 2) Scalability and 3) Creativity. Even though many questions remain regarding their use in the workplace, wearable technologies and Quantified-Self data in the workplace represent an exciting opportunity for the industry and health and safety practitioners who will be using them.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Dissertação de mestrado integrado em Engenharia e Gestão Industrial

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Series: "Advances in intelligent systems and computing , ISSN 2194-5357, vol. 417"

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Tese de Doutoramento em Tecnologias e Sistemas de Informação.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Concrete is the primary construction material for civil infrastructures and generally consists of cement, coarse aggregates, sand, admixtures and water. Cementitious materials are characterized by quasi-brittle behaviour and susceptible to cracking [1]. The cracking process within concrete begins with isolated nano-cracks, which then conjoin to form micro-cracks and in turn macro-cracks. Formation and growth of cracks lead to loss of mechanical performance with time and also make concrete accessible to water and other degrading agents such as CO2, chlorides, sulfates, etc. leading to strength loss and corrosion of steel rebars. To improve brittleness of concrete, reinforcements such as polymeric as well as glass and carbon fibers have been used and microfibers improved the mechanical properties significantly by delaying (but could not stop) the transformation of micro-cracks into macro forms [2]. This fact encouraged the use of nano-sized fillers in concrete to prevent the growth of nano-cracks transforming in to micro and macro forms. Nanoparticles like SiO2, Fe2O3, and TiO2 led to considerable improvement in mechanical performance and moreover, nano-TiO2 helped to remove organic pollutants from concrete surfaces [3].

Relevância:

10.00% 10.00%

Publicador:

Resumo:

O presente artigo tem por objetivo validar uma versão adaptada do Partner Interaction Questionnaire (PIQ), instrumento que avalia o suporte para deixar de fumar dado pelo parceiro. É apresentada uma versão adaptada do PIQ para fumantes e abstinentes. Participaram no estudo 224 fumantes (52.7% do sexo feminino e 47.3% do sexo masculino; média de idades=28.6 anos; DP=8.69) e 169 ex-fumantes (68.6% do sexo masculino e 31.4% do sexo feminino; média de idades= 43.1 anos; DP=13.02). O instrumento apresentou boa fidelidade (alfa de Cronbach: 0.73) para a subescala positiva e para a subescala negativa (alfa de Cronbach: 0.77). O estudo de validade revelou a presença de dois fatores que explicam 43.36% da variância. O instrumento apresenta boa validade de construto, correlacionando-se positivamente com o ajustamento de casais e a qualidade de vida mental, e negativamente com a depressão. Esta versão adaptada do PIQ reuniu as condições necessárias para a sua aplicação em fumantes e ex-fumantes, podendo ser uma escala útil em programas de intervenção de cessação tabágica e de manutenção da abstinência.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Dissertação de mestrado integrado em Engenharia Mecânica

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Rare germline mutations in TP53 (17p13.1) cause a highly penetrant predisposition to a specific spectrum of early cancers, defining the Li-Fraumeni Syndrome (LFS). A germline mutation at codon 337 (p.Arg337His, c1010G>A) is found in about 0.3% of the population of Southern Brazil. This mutation is associated with partially penetrant LFS traits and is found in the germline of patients with early cancers of the LFS spectrum unselected for familial his- tory. To characterize the extended haplotypes carrying the mutation, we have genotyped 9 short tandem repeats on chromosome 17p in 12 trios of Brazilian p.Arg337His carriers. Results confirm that all share a common ancestor haplotype of Caucasian/Portuguese-Ibe- ric origin, distant in about 72–84 generations (2000 years assuming a 25 years intergenera- tional distance) and thus pre-dating European migration to Brazil. So far, the founder p. Arg337His haplotype has not been detected outside Brazil, with the exception of two resi- dents of Portugal, one of them of Brazilian origin. On the other hand, increased meiotic recombination in p.Arg337His carriers may account for higher than expected haplotype diversity. Further studies comparing haplotypes in populations of Brazil and of other areas of Portuguese migration are needed to understand the historical context of this mutation in Brazil.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Dissertação de mestrado em Enfermagem da Pessoa em Situação Crítica

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Tese de Doutoramento em Biologia de Plantas MAP - Bioplant

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Projecto de mestrado em Mediação Cultural e Literária