75 resultados para Spiritual life--Judaism

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The aim of this study was to explore the spirituality of Finnish academically gifted 12 13-year old pre-adolescents (N = 101). Their spirituality was investigated through the following three questions: (1) What is their relationship to religion? (2) How do they perceive transcendence? and (3) How does their search for meaning integrate into their lives? A total of 60 girls and 41 boys participated in the study. They attend a special school, Helsingin Suomalainen yhteiskoulu, in Helsinki, Finland. The school includes classes from grade 3 to upper secondary school and has an entrance test. This study is part of a research project called Actualizing Finnish Giftedness which is funded by the Finnish Academy between 2000 2007 and is led by Professor Tirri. The research project is based on Gardner s Multiple Intelligences theory (Gardner 1993) and on Hay s (1998) work on spirituality. The data in this study was gathered in 2003 and 2004. It includes both qualitative and quantitative material. The emphasis is on data gathered with interviews. The mixed method approach was used as the methodological framework for connecting the qualitative content analysis, phenomenological approach and the quantitative tests of this study. The results of the sub-studies are reported in full in the four original articles. First, the articles show that the pupils connect religion mainly with Christian institutions and do not consider religion and spirituality to overlap. Second, the articles show that the pupils believe in God and the interference of God in their lives and they think that reality includes a spiritual dimension. Third, the pupils had four kinds of existentially significant interests: personal, transcendental, cosmic and ethical. Cosmic interests were especially highlighted in the article concerning boys as nature and science were reported to be integral sources for their existential thinking. In addition, perceptions on God seemed to be connected to the individual s perception on the meaning of life. In RE, spiritual development has been a constant topic of interest since the late eighties. Likewise, recently in gifted education there have been discussions concerning spiritual intelligence (Gardner 1999) and spirituality of the gifted (Kerr & Cohn 2001). Based on the empirical results of the study, this study concludes that education wishing to promote spiritual development should aim at being existentially relevant to the pupils and use their existential search as an integrative framework for their individual talents and skills.

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The aim of this study was to look at the freedom of ordinary people as they construct it. The scope, however, was limited to contemporary Finnish sailors and their freedom discourses. The study belongs to the field of the anthropology of religions, which is part of comparative religion. Worldview, which is one of the key concepts in comparative religion, provided the broader theoretical basis of the study. The data consisted of 92 interviews with Finnish professional seafarers conducted in 1996, 1999, 2000 and 2005, field journals that were written during two periods of fieldwork in 1996 and 1999-2000, and correspondence with some of the seafarers during 1999-2005. The analysis process incorporated new rhetoric and metaphor theory. The thesis is in three parts. The first part discusses the methodological challenges of this type of ethnography, the second an ethnography of modern Finnish shipworld focuses on work, organization, hierarchy and gender, and the third part discusses the freedom concepts of seafarers. It was found that seafarers use two kinds of freedom discourse. The first is in line with the stereotypical Jack Tar, a free-roving sailor who is not bound to land and its mundane routines, and the second views shipworld as freedom from freedom, meaning one is not responsible for one s own actions because one is not free to make a choice. It was also found that seafarers are well aware of the stereotypical images that are attached to their profession: they not only deny them, but also utilize, reflect on and construct them.

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This dissertation analyzes the interrelationship between death, the conditions of (wo)man s social being, and the notion of value as it emerges in the fiction of the American novelist Thomas Pynchon (1937 ). Pynchon s present work includes six novels V. (1963), The Crying of Lot 49 (1966), Gravity s Rainbow (1973), Vineland (1990), Mason & Dixon (1997), Against the Day (2006) and several short stories. Death constitues a central thematic in Pynchon s work, and it emerges through recurrent questions of mortality, suicide, mass destruction, sacrifice, afterlife, entropy, the relationship between the animate and the inanimate, and the limits of representation. In Pynchon, death is never a mere biological given (or event); it is always determined within a certain historical, cultural, and ideological context. Throughout his work, Pynchon questions the strict ontological separation of life and death by showing the relationship between this separation and social power. Conceptual divisions also reflect the relationship between society and its others, and death becomes that through which lines of social demarcation are articulated. Determined as a conceptual and social "other side", death in Pynchon forms a challenge to modern culture, and makes an unexpected return: the dead return to haunt the living, the inanimate and the animate fuse, and technoscientific attempts at overcoming and controlling death result in its re-emergence in mass destruction and ecological damage. The questioning of the ontological line also affects the structuration of Pynchon's prose, where the recurrent narrated and narrative desire to reach the limits of representation is openly associated with death. Textualized, death appears in Pynchon's writing as a sudden rupture within the textual functioning, when the "other side", that is, the bare materiality of the signifier is foregrounded. In this study, Pynchon s cultural criticism and his poetics come together, and I analyze the subversive role of death in his fiction through Jean Baudrillard s genealogy of the modern notion of death from L change symbolique et la mort (1976). Baudrillard sees an intrinsic bond between the social repression of death in modernity and the emergence of modern political economy, and in his analysis economy and language appear as parallel systems for generating value (exchange value/ sign-value). For Baudrillard, the modern notion of death as negativity in relation to the positivity of life, and the fact that death cannot be given a proper meaning, betray an antagonistic relation between death and the notion of value. As a mode of negativity (that is, non-value), death becomes a moment of rupture in relation to value-based thinking in short, rationalism. Through this rupture emerges a form of thinking Baudrillard labels the symbolic, characterized by ambivalence and the subversion of conceptual opposites.

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Taustaa Kehityksellinen dysleksia (lukivaikeus) on erityinen lukemaan oppimisen vaikeus, johon liittyy usein mys vaikeuksia kirjoittamaan oppimisessa. Lukivaikeuden oletetaan useissa tapauksissa johtuvan vaikeudesta ksitell kielen nnerakenteita (fonologinen prosessointi). Tm poikkeavuus voi olla joko lukivaikeuden perimminen syy tai vaihtoehtoisesti ongelmat nteiden ksittelyss voivat heijastaa jotain viel perustavamman tason vaikeutta. Ers tllainen ehdotettu perustavan tasoin syy on poikkeavuus aistien toiminnoissa, erityisesti aistien aikatarkkuudessa. Aikatarkkuudella tarkoitetaan kyky ja rajoja siin, kuinka nopeasti esitetty aistitiedon virtaa henkil kykenee vastaanottamaan ja ksittelemn. Monet arjen toiminnot lukemisen rinnalla edellyttvt aistien erittin tarkkaa ajallista erottelukyky (esimerkiksi kuulo puheen ymmrtmisess, tunto pintamateriaalin tunnistamisessa). Aikatarkkuusvaikeuksien esiintyvyytt lukivaikeudessa on tutkittu aiemminkin, mutta yksimielisyyteen ei ole psty siit, onko kaikilla lukivaikeuksisilla nit ongelmia tai mihin aisteihin vaikeudet mahdollisesti rajoittuvat. Myskn ei tiedet, havaitaanko aikatarkkuuden ongelmia kaiken ikisill lukivaikeuksisilla vai vaihteleeko mahdollinen ongelmien kuva in mukana. Lisksi on epselv, kuinka aikatarkkuuden ongelmat itseasiassa ovat yhteydess kielen ksittelyn ja varsinaisen lukemisen vaikeuksiin. Tutkimussarjan aihe Tss tutkimussarjassa aikatarkkuutta tutkittiin kolmessa yksittisess aistissa, joita olivat tunto, nk ja kuulo, sek kolmessa aistien vlisess yhdistelmss, joita olivat audiotaktiilinen (kuulo-tunto), visuotaktiilinen (nk-tunto) ja audiovisuaalinen (nk-kuulo). Aikatarkkuutta arvioitiin kahdella eri menetelmll, jotta saataisiin lis tietoa siit, miss tietyss aikatarkkuuden osa-alueessa lukivaikeuksisilla mahdollisesti on vaikeuksia. Ensimmisess tehtvss tutkittavan tuli arvioida, ovatko esitetyt ei-kielelliset rsykkeet samanaikaisia vai eriaikaisia. Toisessa tehtvss koehenkiln tuli arvioida esitettyjen ei-kielellisten rsykkeiden esitysjrjestys. Molemmissa tehtviss mriteltiin millisekuntitasolla (sekunnin tuhannesosa) se esitysnopeus, jolla koehenkil kykeni arvioimaan rsykkeiden ajalliset suhteet oikein. Englanninkielinen demonstraatio aikatarkkuustehtvist lytyy internetist (http://www.helsinki.fi/hum/ylpsy/neuropsy). Itse aikatarkkuustehtvien lisksi tutkimussarjassa arvioitiin tutkimushenkiliden pttelykyky, kielellisi toimintoja ja lukemista. Tutkimushenkilt Tutkimuksiin osallistui 53 lukivaikeuksista ja 66 sujuvaa lukijaa, jotka oli jaettu kolmeen pikryhmn: lapset (8-12 vuotta), nuoret aikuiset (20-36 vuotta) ja ikntyneemmt aikuiset (20-59 vuotta). Ikntyneempien aikuisten ryhm oli edelleen jaettu ikvuosikymmenluokkiin, mik mahdollisti sen tutkimisen, vaikuttaako lisntyv aikuisik lukivaikeuksisten aikatarkkuuteen (20-29, 30-39, 40-49 ja 50-59 -vuotiaat). Tutkimussarjan tulokset Aikatarkkuuden ongelmat lukivaikeuksisilla olivat yleistyneit yli in, aistien ja tehtvien Lukivaikeuksiset kaikissa pikryhmiss (lapset, nuoret aikuiset, ikntyneemmn aikuiset) tarvitsivat samanikisi sujuvia lukijoita hitaamman esitystahdin, jotta he kykenivt arvioimaan ei-kielellisten rsykkeiden ajallisen esitystavan oikein. Tm aikatarkkuuden ongelma havaittiin lukivaikeuksisilla kaikissa aisteissa (tunto, kuulo, nk) ja niiden yhdistelmiss (audiotaktiilinen, visuotaktiilinen, audiovisuaalinen). Lukivaikeuksisten aikatarkkuusongelmat ilmenivt edelleen molemmissa tehtvtyypeiss (samanaikaisuuden ja jrjestyksen arvioinnissa). Aikatarkkuus ja sen ongelmat olivat yhteydess nteiden ksittelyyn Aikatarkkuus oli yhteydess nteiden ksittelykykyyn (fonologiseen prosessointiin), niin lapsilla kuin aikuisillakin, kaikissa aisteissa, niiden yhdistelmiss ja tehtvtyypeiss. Yhteys ei-kielellisen aikatarkkuuden ja kielellisten toimintojen vlill oli kuitenkin selkempi lukivaikeuksisilla kuin sujuvilla lukijoilla. Tm tarkoittaa, ett etenkin lukivaikeuksisilla ryhmtason huono aikatarkkuus oli yhteydess huonoon nteiden ksittelyyn (fonologiseen prosessointiin) ja pinvastoin. Suoraa yhteytt lukemisen ja aikatarkkuuden vlill ei kuitenkaan havaittu. Lisntyv aikuisik heikensi lukivaikeuksisten aikatarkkuutta suhteettoman paljon Tiedonksittelyn nopeuden on toistuvasti osoitettu hidastuvan normaalissa ikntymisess. Lisntyv aikuisik (20-59 -vuotiailla) heikensikin sek sujuvien ett lukivaikeuksisten aikatarkkuutta. Toisin sanoen, mit ikkmmst aikuisesta oli kysymys, sit hitaammin hnelle tuli esitt rsykkeet, jotta hn kykeni arvioimaan niiden ajalliset suhteet oikein. Tm ikn liittyv tavanomainen hidastuminen oli kuitenkin ylltten suhteettoman nopeaa lukivaikeuksisilla. Toisin sanoen, jo nuorilla lukivaikeuksisilla havaittu aikatarkkuuden vaikeus (ryhmero verrattuna sujuviin lukijoihin) ei pysynyt saman suuruisena, vaan ryhmien ero kasvoi aikuisin lisntyess. Tulosten merkitys Lukivaikeuden osoitettiin tss tutkimussarjassa olevan yhteydess yleistyneeseen vaikeuteen ksitell ajassa nopeasti muuttuvaa ei-kielellist aistitietoa (yli aistien ja niiden yhdistelmien, tehtvtyyppien, tutkittavien in). Tm osoittaa, ett lukivaikeus ei ole ongelma, joka rajoittuu vain kielellisen materiaalin ksittelyn vaikeuksiin (nteiden ksittely, lukeminen, kirjoittaminen). Nyt havaitut vaikeudet eivt myskn rajoittuneet vain niihin aisteihin, jotka selkeimmin liittyvt lukemiseen (nk) ja puhuttuun kieleen (kuulo); Ongelmia esiintyi mys muissa aisteissa (tunto). Lukivaikeuksisten lukijoiden ryhmtasolla havaittu aikatarkkuuden ongelma ei kuitenkaan heijastunut yksiltasolle; Jokainen lukivaikeuksinen ei ollut huono aikatarkkuustehtviss. Nin ollen ei siis voida vitt, ett kaikkien lukivaikeuksisten nteiden ksittelyn tai lukemaan oppimisen vaikeudet voisivat selitty aistien toimintojen poikkeavuudella. Aikatarkkuuden ongelmat eivt olleet yhteydess varsinaiseen lukemiseen. Sek lukivaikeuksisilla lapsilla ett aikuisilla todettiin kuitenkin selke yhteys aikatarkkuuden ongelmien ja lukemaan oppimisen keskeisen ennakkoehdon, fonologisen prosessoinnin, vlill. Saattaa siis olla, ett synnynninen aistien toimintojen poikkeavuus vaikuttaa yksiln suoriutumiseen jo ennen varsinaista lukemaan oppimista, kun ne taidot kehittyvt (fonologinen prosessointi), joille myhempi lukemaan oppiminen perustuu. Iknnyttess havaittu lukivaikeuksisten suhteettoman nopea aikatarkkuuden heikkeneminen osoittaa, ett lukivaikeus ei voi olla ongelma, joka koskee vain lapsuusik, tai vaikeus, joka johtuu vain kehityksen viivstymst joka kurottaisiin in myt umpeen. Tulosten ymmrtmiseksi onkin muistettava kaksi seikkaa. Lukivaikeus on ensinnkin yhdistetty synnynnisiin, pieniin, poikkeavuuksiin aivojen rakenteissa ja toiminnoissa. Toisaalta tavanomaiseen ikntymiseen liittyy se, ett aivot kykenevt yh huonommin korjaamaan ja kiertmn (kompensoimaan) pieni vaurioita. Tmn perusteella tutkimussarjan tuloksista voidaan ptell, ett lukivaikeuksisten jo synnynnisesti heikentyneet aivojen kompensointimahdollisuudet eivt ole yht tehokkaita puskuroimaan ikntymisen tavanomaisia vaikutuksia kuin sujuvilla lukijoilla. Yllttv kuitenkin on, ett tm korostunut heikkeneminen havaittiin jo suhteellisen nuorilla, tyikisill, lukivaikeuksisilla, ennen 60 ikvuotta. Samanlaista iknnyttess korostuvaa vaikeutta ei lukivaikeuksilla kuitenkaan havaittu pttelyss, kielellisiss toiminnoissa tai itse lukemisessa. Vaikuttaakin siis silt, ett ne toiminnot, joita on harjaannutettu aktiivisesti, eivt heikkene kasvavan aikuisin myt yht suhteettomasti. Alkuperiset artikkelit Laasonen M, Tomma-Halme J, Lahti-Nuuttila P, Service E, and Virsu V (2000) Rate of information segregation in developmentally dyslexic children, Brain and Language, 75(1), 66-81. Laasonen M, Service E, and Virsu V (2001) Temporal order and processing acuity of visual, auditory, and tactile perception in developmentally dyslexic young adults, Cognitive, Affective, and Behavioral Neuroscience, 1(4), 394-410. Laasonen M, Service E, and Virsu V (2002) Crossmodal temporal order and processing acuity in developmentally dyslexic young adults, Brain and Language, 80(3), 340-354. Laasonen M, Lahti-Nuuttila P, and Virsu V (2002) Developmentally impaired processing speed decreases more than normally with age, NeuroReport, 13(9), 1111-1113.

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The focus of this study was to examine the constructions of the educable subject of the lifelong learning (LLL) narrative in the narrative life histories of adult students at general upper secondary school for adults (GUSSA). In this study lifelong learning has been defined as a cultural narrative on education, a system of political thinking that is not internally consistent, but has contradictory themes embedded within it (Billig et al., 1988). As earlier research has shown and this study also confirms, the LLL narrative creates differences between those who are included and those who fall behind and are excluded from the learning society ideal. Educability expresses socially constructed interpretations on who benefit from education and who should be educated and how. The presupposition in this study has been that contradictions between the LLL narrative and the so-called traditional constructions of educability are likely to be constructed as the former relies on the all-inclusive interpretation of educability and the latter on the meritocratic model of educating individuals based on their innate abilities. The school system continues to uphold the institutionalized ethos of educability that ranks students into the categories bright, mediocre, and poor (Rty & Snellman, 1998) on the basis of their abilities, including gender-related differences as well as differences based on social class. Traditional age-related norms also persist, for example general upper secondary education is normatively completed in youth and not in adulthood, and the formal learning context continues to outweigh both non-formal and informal learning. Moreover, in this study the construction of social differences in relation to educability and, thereafter unequal access to education has been examined in relation to age, social class, and gender. The biographical work of the research participants forms a peephole that permits the examination of the dilemmatic nature of the constructions of educability in this study. Formal general upper secondary education in adulthood is situated on the border between the traditional and the LLL narratives on educability: participation in GUSSA inevitably means that ones ability and competence as a student and learner becomes reassessed through the assessment criteria maintained by schools, whereas according to the principles of LLL everyone is educable; everyone is encouraged to learn throughout their lives regardless of age, social class, or gender. This study is situated in the field of adult education, sociology of education, and social psychological research on educability, having also been informed by feminist studies. Moreover, this study contributes to narrative life history research combining the structural analysis of narratives (Labov & Waletzky, 1997), i.e. mini-stories within life history, with the analysis of the life histories as structural and thematic wholes and the creation of coherence in them; thus, permitting both micro and macro analyses. On accounting for the discontinuity created by participation in general upper secondary school study in adulthood and not normatively in youth, the GUSSA students construct coherence in relation to their ability and competence as students and learners. The seven case studies illuminate the social differences constructed in relation to educability, i.e. social class, gender, age, and the new category of student and learner. In the data of this study, i.e. 20 general upper secondary school adult graduates narrative life histories primarily generated through interviews, two main coherence patterns of the adult educable subject emerge. The first performance-oriented pattern displays qualities that are closely related to the principles of LLL. Contrary to the principles of lifewide learning, however, the documentation of ones competence through formal qualifications outweighs non-formal and informal learning in preparation for future change and the competition for further education, professional careers, and higher social positions. The second flexible learning pattern calls into question the status of formal, especially theoretical and academically oriented education; inner development is seen as more important than such external signs of development grades and certificates. Studying and learning is constructed as a hobby and as a means to a more satisfactory life as opposed to a socially and culturally valued serious occupation leading to further education and career development. Consequently, as a curious, active, and independent learner, this educable but not readily employable subject is pushed into the periphery of lifelong learning. These two coherence patterns of the adult educable subject illuminate who is to be educated and how. The educable and readily employable LLL subject is to participate in formal education in order to achieve qualifications for working life, whereas the educable but not employable subject may utilize lifewide learning for her/his own pleasure. Key words: adult education, general upper secondary school for adults, educability, lifelong learning, narrative life history

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Increased mass migration, as a result of economic hardship, natural disasters and wars, forces many people to arrive on the shores of cultures very different from those they left. How do they manage the legacy of the past and the challenges of their new everyday life? This is a study of immigrant women living in transnational families that act and communicate across national borders on a near-daily basis. The research was carried out amongst immigrant women who were currently living in Finland. The research asks how transnational everyday life is constructed. As everyday life, due to its mundane nature, is difficult to operationalise for research purposes, mixed data collection methods were needed to capture the passing moments that easily become invisible. Thus, the data were obtained from photographic diaries (459 photographs) taken by the research participants themselves. Additionally, stimulated recall discussions, structured questionnaires and participant observation notes were used to complement the photographic data. A tool for analysing the activities devealed in the data was created on the assumption that a family is an active unit that accommodates the current situation in which it is embedded. Everyday life activities were analysed emphasizing social, modal and spatial dimensions. Important daily moments were placed on a continuum: for me , for immediate others and with immediate others . They portrayed everyday routines and exceptions to it. The data matrix was developed as part of this study. The spatial dimensions formed seven units of activity settings: space for friendship, food, resting, childhood, caring, space to learn and an orderly space. Attention was also paid to the accommodative nature of activities; how women maintain traditions and adapt to Finnish life or re-create new activity patterns. Women s narrations revealed the importance of everyday life. The transnational chain of women across generations and countries, comprised of the daughters, mothers and grandmothers was important. The women showed the need for information technology in their transnational lives. They had an active relationship to religion; the denial or importance of it was obvious. Also arranging one s life in Finnish society was central to their narrations. The analysis exposed everyday activities, showed the importance of social networks and the uniqueness of each woman and family. It revealed everyday life in a structured way. The method of analysis that evolved in this study together with the research findings are of potential use to professionals, allowing the targeting of interventions to improve the everyday lives of immigrants.

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Background and aims. Fatness and dieting have been the object of interest between many fields for a long time. Home economics as a discipline enables a comprehensive inspection of fatness and dieting reviewing different disciplines. In addition to the aspect where the pursuit of dieting and health is seen from the perspective of medical and health science it is also been reviewd as a social and cultural phenomena. This study contemplates the influence of history, religion, medicalization and media on dieting and health culture. The objective is to find out if the modern dieting and health culture has gathered influences from centuries ago and absorbed religious features. The stress deriving from appereance has been discussed in the public and there are many solutions conserning weight issues. The purpose of this study is to find out what personal experiences and thoughts female pastors have conserning these questions. The media which is one of the most influential systems nowadays has undeniably a great effect on the consumer. The goal is furthermore to estimate the effect of the media on the changing of dieting and health culture. The three main research questions are: 1. What kind of conseptions do female pastors have of dieting and health culture and of its religious features? 2. What kind of personal experiences and conseptions do female pastors have of dieting and strivines of health? 3. How do female pastors regard the image the media has supplied of dieting and health culture? Material and methods. The qualitative data was gathered in year 2009 using the halfstructured theme interview -method. The data consists of interviews conducted with specialists of spiritual matters, i.e. ten female pastors who are between 35 and 60 years old and live in the metropolitan area. The analytical procedure used is called a theory based context analysis. Results and conclusions. Results of this study show that the idealization of slimness and healthiness is a matter discussed in the public on a daily basis. The problem faced was that the media provided contradictory information regarding fatness and dieting and the standard of slimness in commercials focused on females. The pursuit of dieting and healthiness was believed to include also religious elements. In the Middle Ages and the era after that the fatness, overeating and the pleasure one gets from eating was still seen as a condemnable matter in our culture. One could say this was like a sin. The respondents believed that healthiness, healthy living, optimal eating and good looks were a matter more or less equal than a religion. This was a derivative from the fact that treasuring health has become a life stearing value for many people. In the priests profession dieting and the pursuit of health was seen in the light of problems arising from weight issues. In ones profession for example the unhealthy eating in festive situations was seen as a matter that leads to unnecessary weight. Another aspect was the job circumstances that limited the degree of movement. The belief was that the female pastors would in a decreasing fashion confront stress deriving from appearence in their job. Keywords: dieting, fatness, healthiness, slimness, female pastors, religion, medicalization, media

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Aims: The aims of this study were 1) to identify and describe health economic studies that have used quality-adjusted life years (QALYs) based on actual measurements of patients' health-related quality of life (HRQoL); 2) to test the feasibility of routine collection of health-related quality of life (HRQoL) data as an indicator of effectiveness of secondary health care; and 3) to establish and compare the cost-utility of three large-volume surgical procedures in a real-world setting in the Helsinki University Central Hospital, a large referral hospital providing secondary and tertiary health-care services for a population of approximately 1.4 million. Patients and methods: So as to identify studies that have used QALYs as an outcome measure, a systematic search of the literature was performed using the Medline, Embase, CINAHL, SCI and Cochrane Library electronic databases. Initial screening of the identified articles involved two reviewers independently reading the abstracts; the full-text articles were also evaluated independently by two reviewers, with a third reviewer used in cases where the two reviewers could not agree a consensus on which articles should be included. The feasibility of routinely evaluating the cost-effectiveness of secondary health care was tested by setting up a system for collecting HRQoL data on approximately 4 900 patients' HRQoL before and after operative treatments performed in the hospital. The HRQoL data used as an indicator of treatment effectiveness was combined with diagnostic and financial indicators routinely collected in the hospital. To compare the cost-effectiveness of three surgical interventions, 712 patients admitted for routine operative treatment completed the 15D HRQoL questionnaire before and also 3-12 months after the operation. QALYs were calculated using the obtained utility data and expected remaining life years of the patients. Direct hospital costs were obtained from the clinical patient administration database of the hospital and a cost-utility analysis was performed from the perspective of the provider of secondary health care services. Main results: The systematic review (Study I) showed that although QALYs gained are considered an important measure of the effectiveness of health care, the number of studies in which QALYs are based on actual measurements of patients' HRQoL is still fairly limited. Of the reviewed full-text articles, only 70 reported QALYs based on actual before after measurements using a valid HRQoL instrument. Collection of simple cost-effectiveness data in secondary health care is feasible and could easily be expanded and performed on a routine basis (Study II). It allows meaningful comparisons between various treatments and provides a means for allocating limited health care resources. The cost per QALY gained was 2 770 for cervical operations and 1 740 for lumbar operations. In cases where surgery was delayed the cost per QALY was doubled (Study III). The cost per QALY ranges between subgroups in cataract surgery (Study IV). The cost per QALY gained was 5 130 for patients having both eyes operated on and 8 210 for patients with only one eye operated on during the 6-month follow-up. In patients whose first eye had been operated on previous to the study period, the mean HRQoL deteriorated after surgery, thus precluding the establishment of the cost per QALY. In arthroplasty patients (Study V) the mean cost per QALY gained in a one-year period was 6 710 for primary hip replacement, 52 270 for revision hip replacement, and 14 000 for primary knee replacement. Conclusions: Although the importance of cost-utility analyses has during recent years been stressed, there are only a limited number of studies in which the evaluation is based on patients own assessment of the treatment effectiveness. Most of the cost-effectiveness and cost-utility analyses are based on modeling that employs expert opinion regarding the outcome of treatment, not on patient-derived assessments. Routine collection of effectiveness information from patients entering treatment in secondary health care turned out to be easy enough and did not, for instance, require additional personnel on the wards in which the study was executed. The mean patient response rate was more than 70 %, suggesting that patients were happy to participate and appreciated the fact that the hospital showed an interest in their well-being even after the actual treatment episode had ended. Spinal surgery leads to a statistically significant and clinically important improvement in HRQoL. The cost per QALY gained was reasonable, at less than half of that observed for instance for hip replacement surgery. However, prolonged waiting for an operation approximately doubled the cost per QALY gained from the surgical intervention. The mean utility gain following routine cataract surgery in a real world setting was relatively small and confined mostly to patients who had had both eyes operated on. The cost of cataract surgery per QALY gained was higher than previously reported and was associated with considerable degree of uncertainty. Hip and knee replacement both improve HRQoL. The cost per QALY gained from knee replacement is two-fold compared to hip replacement. Cost-utility results from the three studied specialties showed that there is great variation in the cost-utility of surgical interventions performed in a real-world setting even when only common, widely accepted interventions are considered. However, the cost per QALY of all the studied interventions, except for revision hip arthroplasty, was well below 50 000, this figure being sometimes cited in the literature as a threshold level for the cost-effectiveness of an intervention. Based on the present study it may be concluded that routine evaluation of the cost-utility of secondary health care is feasible and produces information essential for a rational and balanced allocation of scarce health care resources.

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The study is part of a research project of 269 psychiatric patients with major depression, Vantaa Depression Study, in the Department of Mental Health and Alcohol Research of the National Public Health Institute and the Department of Psychiatry of the Peijas Medical Care District. The aim was to study at the onset of MDE psychosocial differences in subgroups of patients and clustering of events into time before depression and its prodromal phase, to study whether more severe life events and less social support predict poorer outcome in all patients, but most among those currently in partial remission, whether social support declines as a consequence of time spent in MDE, is sensitive to improvement, and whether social support is influenced by neuroticism and extraversion. After screening, a semistructured interview (SCAN, version 2.0) was used for the presence of DSM-IV MDE, and other psychiatric diagnoses. Life events and social support were studied with semistructured methods (IRLE, Paykel 1983; IMSR, Brugha et al. 1987), perceived social support and neuroticism/extraversion with questionnaires (PSSS-R, Blumenthal et al. 1987; EPI, Eysenck and Eysenck 1964) at baseline, 6 and 18 months. At the onset of depression life events were common. No major differences between subgroups of patients were found; the younger had more events, whereas those with comorbid alcoholism and personality disorders perceived less support. Although events were distributed evenly between the time before depression, the prodromal phase and the index MDE, two thirds of the patients attributed their depression to some life event. Adversities and poor perceived support influenced the outcome of all psychiatric patients, most in the subgroup of full remission. In the partial remission group, the impact of severe events and in the MDE, perceived support was important. Low objective and subjective support were predicted by longer time spent in MDE. Along with improvement subjective support improved. Neuroticism and extraversion were associated with the size of social network and perceived support and predicted change of perceived support. In conclusion, adversities were common in all phases of depression. They may thus have many roles; before depression they may precipitate it, in the prodromal phase worsen symptoms, and during the MDE, the outcome of depression. Patients often attributed their depression to a life event. Psychosocial subgroup differences were quite small. Perceived support predicted the outcome of depression, and time spent in MDE objective and subjective support. Neuroticism and extraversion may modify the level and change particularly in perceived support, thereby indirectly effecting vulnerability to depression.

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Vitskirjani ksittele mikrobien ja erilaisten kemikaalien rooleja saostumien ja biofilmien muodostumisessa paperi- ja kartonkikoneilla. "Saostuma" tss tyss tarkoittaa kiinten aineen kertym konepinnoille tai rajapinnoille konekierroissa, jotka on tarkoitettu massasulppujen, lietteiden, vesien tai ilman kuljetukseen. Saostumasta tulee "biofilmi" silloin kun sen oleellinen rakennekomponentti on mikrobisolut tai niiden tuotteet. Vitstyni tyhypoteesina oli, ett i. tietmys saostumien koostumuksesta, sek ii. niiden rakenteesta, biologisista, fysikaalis-kemiallisista ja teknisist ominaisuuksista ohjaavat tutkijaa lytmn ymprist sstvi keinoja est eptoivottujen saostumien muodostus tai purkaa jo muodostuneita saostumia. Selvittkseni saostumien koostumista ja rakennetta kytin monia erilaisia analytiikan tykaluja, kuten elektronimikroskopiaa, konfokaali-laser mikroskopiaa (CLSM), energiadispersiivist rntgenanalyysi (EDX), pyrolyysi kaasukromatografiaa yhdistettyn massaspektrometriaan (Py-GCMS), joninvaihtokromatografiaa, kaasukromatografiaa ja mikrobiologisia analyysej. Osallistuin aktiivisesti innovatiivisen, valon takaisinsirontaan perustuvan sensorin kehittmistyhn, kytettvksi biofilmin kasvun mittaukseen suoraan koneen vesikierroista ja siliist. Tyni osoitti, ett monet paperinvalmistuksessa kytetyist kemikaaleista reagoivat keskenn tuottaen orgaanisia tahmakerroksia konekiertojen terspinnoille. Lysin mys kerrostumia, jotka valomikroskooppisessa tarkastelussa oli tulkittu mikrobeiksi, mutta jotka elektronimikroskopia paljasti alunasta syntyneiksi, alumiinihydroksidiksi joka saostui pH:ssa 6,8 kiertokuitua kyttvn koneen viiravesist. Monet paperintekijt kyttvt vielkin alunaa kiinnitysaineena vaikka prosessiolot ovat muuttuneet happamista neutraaleiksi. Sit pidetn paperitekijn "aspiriinina", mutta vitstutkimukseni osoitti sen riskit. Lysin mys orgaanisia saostumia, joiden alkuper oli aineiden, kuten pihkan, saippuoituminen (kalsium saippuat) niin ett muodostui tahmankasvua yllpitv alusta monilla paperi- ja kartonkikoneilla. Nin solumuodoiltaan Deinococcus geothermalista muistuttavia bakteereita kasvamassa lujasti terskoepalojen pintaan kiinnittynein peskkein, kun koepaloja upotettiin paperikoneiden vesikiertoihin. Nm deinokokkimaiset peskkeet voivat toimia jalustana, tarttumisalustana muiden mikrobien massoille, joka selittisi miksi saostumat yleisesti sisltvt deinokokkeja pienen, muttei koskaan pasiallisena rakenneosana. Kun paperikoneiden kyttmien vesien (raakavedet, lmminvesi, biologisesti puhdistettu jtevesi) laatua tutkitaan, mittausmenetelmll on suuri merkitys. Koepalan upotusmenetelmll todettu biofilmikasvu ja viljelmenetelmll mitattu bakteerisaastuneisuus korreloivat toisiinsa huonosti etenkin silloin kun likaantumisessa oli mukana rihmamaiseti kasvavia bakteereja. Huoli ympristst on pakottanut paperi- ja kartonkikoneiden vesikiertojen sulkemiseen. Vesien kierrtys ja prosessivesien uudelleenkytt nostavat prosessilmptilaa ja lisvt koneella kiertvien kolloidisten ja liuenneiden aineiden mri. Tutkin kiertovesien pitoisuuksia kolmessa eriasteisesti suljetussa tehtaassa, joiden pstt olivat 0 m3, 0,5 m3 ja 4 m3 jtevett tuotetonnia kohden, perustuen puhdistetun jteveden uudelleen kyttn. Nollapstisell tehtaalla kiertovesiin kertyi paljon orgaanisesti sidottua hiilt (> 10 g L-1), etenkin haihtuvina happoina (maito-, etikka-, propioni- ja voi-). Mys sulfaatteja, klorideja, natriumia ja kalsiumia kertyi paljon, > 1 g L-1 kutakin. Posa (>40%) kaikista bakteereista oli 16S rRNA geenisekvenssianalyysien tulosten perusteella sukua, joskin etist (< 96%) ainoastaan Enterococcus cecorum bakteerille. 4 m3 pstvlt tehtaalta lytyi lisksi Bacillus thermoamylovorans ja Bacillus coagulans. Tehtaiden saostumat sislsivt arkkeja suurina pitoisuuksina, 108 g-1, mutta tunnistukseen riittv sekvenssisamanlaisuutta lytyi vain yhteen arkkisukuun, Methanothrix. Tutkimustulokset osoittivat ett tehtaan vesikiertojen sulkeminen vhensi rajusti mikrobiston monimuotoisuutta, muttei estnyt liuenneen aineen ja kiintoaineen mineralisoitumista.