39 resultados para WorldCat UMD
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This presentation provided the results of a two-round iterative study of WorldCat UMD usability.
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Poster presentation at the University of Maryland Libraries Research & Innovative Practice Forum on June 8, 2016. The poster proposes that the UMD Libraries should evaluate adoption of Bento Box Discovery for improved user search experience.
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Presented at the 2016 Library Research and Innovative Practice Forum, this poster provides an overview of a successful partnership between the University of Maryland Archives and UMD's Gymkana Troupe to publicize Gymkana's 70th anniversary and to digitize the troupe's holdings in the Archives. Gymkana is an exhibition gymnastics troupe founded on campus in 1946 which runs a variety of educational and healthy-living outreach programs. Various stages of the project are highlighted, including an exhibit in McKeldin Library, a LaunchUMD fundraising campaign, and the troupe's participation in metadata creation for digital objects. By maintaining an open and flexible dialogue throughout the project planning and execution, both the library and the troupe members ultimately benefited from this collaboration.
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კვლევა მოიცავს შოთა რუსთაველის პოემის, ვეფხისტყაოსნის თარგმანების არსებობას ევროპის ეროვნული ბიბლიოთეკების კატალოგებში და WorldCat-ში.
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Analyzing the type and frequency of patient-specific mutations that give rise to Duchenne muscular dystrophy (DMD) is an invaluable tool for diagnostics, basic scientific research, trial planning, and improved clinical care. Locus-specific databases allow for the collection, organization, storage, and analysis of genetic variants of disease. Here, we describe the development and analysis of the TREAT-NMD DMD Global database (http://umd.be/TREAT_DMD/). We analyzed genetic data for 7,149 DMD mutations held within the database. A total of 5,682 large mutations were observed (80% of total mutations), of which 4,894 (86%) were deletions (1 exon or larger) and 784 (14%) were duplications (1 exon or larger). There were 1,445 small mutations (smaller than 1 exon, 20% of all mutations), of which 358 (25%) were small deletions and 132 (9%) small insertions and 199 (14%) affected the splice sites. Point mutations totalled 756 (52% of small mutations) with 726 (50%) nonsense mutations and 30 (2%) missense mutations. Finally, 22 (0.3%) mid-intronic mutations were observed. In addition, mutations were identified within the database that would potentially benefit from novel genetic therapies for DMD including stop codon read-through therapies (10% of total mutations) and exon skipping therapy (80% of deletions and 55% of total mutations).
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Purpose - This article describes the use of web services to interconnect the GTBib interlibrary loan program with the OCLC WorldShare platform. Design/methodology/approach - We describe the current problem of duplication of procedures in libraries that have added their collections to the OCLC WorldCat catalogue in recent years and are therefore more likely to receive interlibrary loan requests through the WorldShare Platform. Findings - A solution that uses web services to insert and retrieve requests between the two systems is presented. Autonomous agents periodically check the status of the requests and keep them updated and synchronized. These agents also inform the library staff of any variation or inconsistency that is detected. Practical Implications - This technology reduces process management time by making it unnecessary to introduce the request data in both systems. Agents are used to check the consistency of statuses between the two systems, thus avoiding errors and omissions and improving the efficiency of the whole interlibrary loan process. Originality/value - This paper describes in detail the technical aspects of the solution as a reference for the development of future applications.
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Poster at Open Repositories 2014, Helsinki, Finland, June 9-13, 2014
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Las redes sociales digitales han transformado la forma de comunicarse en el Siglo XXI. Twitter es la red social más destacada para los periodistas colombianos pues según un estudio de la consultora de comunicación Burson-Marsteller, el 47% de los comunicadores colombianos utilizan esta red social para construir noticias (Burson-Marsteller, 2013). Por su popularidad, los medios de comunicación han puesto la mirada sobre esta red social pues ven en esta un nuevo espacio de información, razón por la cual se han transformado para convertir a Twitter en un nuevo conducto para la transmisión de sucesos coyunturales. En Colombia, los medios periodísticos de tradición intentan modificar su estructura y rutinas para adecuarse al nuevo molde comunicativo que propone la inclusión de las redes sociales digitales. Este artículo intenta desvelar cuáles son esos cambios que ha sufrido el periodismo colombiano, teniendo como base su relación con Twitter.
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Este texto ilustra la interacción entre violencia estructural y actores marginales para ver cómo lo primero crea lo segundo, y cómo, a su turno, la dinámica de estos actores les permite articularse y/o fugarse de sus condiciones. Si los actores de un espacio social determinado pueden llevar a cabo una acción que mínimamente los reproduce, sus condiciones y las relaciones de poder, esto es, una acción reflexionada, podría generar un cambio. Pero para no quedarse en los extremos viendo las maquinarias del poder sobre unos sujetos y sus acciones diarias, siempre condicionadas por aquellas, se puede comprobar el ámbito de autonomía de las decisiones que movilizan su acción, y medir el poder de esta tanto individual como colectiva, amarrada a unos fines: hacia la reafirmación de la identidad o en procura de lograr un cambio
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El Catholic Worker Movement se ha caracterizado por enmarcarse en las dinámicas de movilización social y acción política no violenta, que respondían, desde su creación en 1933, a un conjunto de problemáticas sociales y económicas sobre las cuales la sociedad civil se interesó y dio inicio a su actividad en escenarios de la política doméstica de Estados Unidos. Pese a ser un movimiento que surgió en un contexto nacional con fundamentación religiosa, el CWM alcanzó el desarrollo de lógicas transnacionales que contribuyeron a la defensa de su causa y a la reivindicación de valores y principios que motivarían posteriormente a la búsqueda de recursos para reforzar su lucha. Así, el proceso de evolución del movimiento tomó dirección en torno a fenómenos como la difusión, la adquisición de repertorios de acción colectiva correspondientes a la no violencia, y al aprovechamiento de factores exógenos y endógenos representados en distintas formas de oportunidad política y capacidad organizativa.
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Resumen basado en el de la publicaci??n
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The chaperone/usher pathway controls assembly of fibres of adhesive organelles of Gram-negative bacteria. The final steps of fibre assembly and fibre translocation to the cell surface are co-ordinated by the outer membrane proteins, ushers. Ushers consist of several soluble periplasmic domains and a single transmembrane beta-barrel. Here we report isolation and structural/functional characterization of a novel middle domain of the Caf1A usher from Yersinia pestis. The isolated UMD (usher middle domain) is a highly soluble monomeric protein capable of autonomous folding. A 2.8 angstrom (1 angstrom = 0.1 nm) resolution crystal structure of UMD revealed that this domain has an immunoglobulin-like fold similar to that of donor-strand-complemented Caf1 fibre subunit. Moreover, these proteins displayed significant structural similarity. Although UMD is in the middle of the predicted amphipathic beta-barrel of Caf1A, the usher still assembled in the membrane in the absence of this domain. UMD did not bind Caf1M-Caf1 complexes, but its presence was shown to be essential for Caf1 fibre secretion. The study suggests that UMD may play the role of a subunit-substituting protein (dummy subunit), plugging or priming secretion through the channel in the Caf1A usher. Comparison of isolated UMD with the recent strcture of the corresponding domain of PapC usher revealed high similarity of the core structures, suggesting a universal structural adaptation of FGL (F(1)G(1) long) and FGS (F(1)G(1) short) chaperone/usher pathways for the secretion of different types of fibres. The functional role of two topologically different states of this plug domain suggested by structural and biochemical results is discussed.