166 resultados para MEF
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Comunicação apresentada no 8º Congresso Nacional de Administração Pública – Desafios e Soluções, em Carcavelos de 21 a 22 de Novembro de 2011.
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La finalitat del nostre va ser valorar l’aplicació d’un programa d’intervenció específic per a millorar la flexibilitat en un grup d’escolars de 9 anys. Van ser inclosos en l’estudi 63 escolars de 4º curs d’Educació Primària, del Centre Escolar la Salle i el CEIP St. Ignasi, ambdós de Manresa (Barcelona). Durant tres setmanes, el centre La Salle va aplicà un programa específic per a millorar la flexibilitat de la cadena cinètica posterior. En canvi, el CEIP St. Ignasi es va utilitzar com a grup control, continuant el seu programa educatiu habitual. Hem observat que l’aplicació de programes específics per a millorar la flexibilitat és efectiva en los escolares de 9 anys. La forma de aplicar els programes de educació física modifica significativament el grau de flexibilitat en los escolares.
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Muscle-type carnitine palmitoyltransferase 1 (CPT1β) is considered to be the gene that controls fatty acid mitochondrial β-oxidation. A functional peroxisome proliferator-activated receptor (PPAR) responsive element (PPRE) and a myocite-specific (MEF2) site that binds MEF2A and MEF2C in the promoter of this gene had been previously identified. We investigated the roles of the PPRE and the MEF2 binding sites and the potential interaction between PPARα and MEF2C regulating the CPT1β gene promoter. Mutation analysis indicated that the MEF2 site contributed to the activation of the CPT1β promoter by PPAR in C2C12 cells. The reporter construct containing the PPRE and the MEF2C site was synergistically activated by co-expression of PPAR, retinoid X receptor (RXR) and MEF2C in non-muscle cells. Moreover, protein-binding assays demonstrated that MEF2C and PPAR specifically bound to one another in vitro. Also for the synergistic activation of the CPT1β gene promoter by MEF2C and PPARα-RXRα, a precise arrangement of its binding sites was essential.
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Pós-graduação em Odontologia - FOA
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Pós-graduação em Odontologia - FOA
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Pós-graduação em Odontologia - FOA
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Pós-graduação em Odontologia - FOA
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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The aim of this study was to evaluate the biomechanical behavior of different implant connection types, by means of three-dimensional finite element analysis. 3 Three-dimensional models were created with a graphic modeling software: SolidWorks 2006 and Rhinoceros 4.0, and InVesalius (CTI, São Paulo, Brasil), the bone was obtained by computerized tomography of a sagittal section of the molar region. The model was composed by bone block with an implant (4 x 10 mm) (Conexão Sistemas de Prótese, São Paulo), with different implant connections: external hex, internal hex and Morse-taper with the corresponding prosthetic component Ucla or Morse-taper abutment. The Three-dimensional models were transferred to finite element software Femap 10.0 (Siemens PLM Software Inc., CA, USA), to generate a mesh, boundary conditions and loading. An axial (200N) and oblique load (100N) was applied on the occlusal surface of the crowns. Analyses were performed using the finite element software NEiNastran 9.0 (Noran Engineering, Inc., USA) and transferred to the Femap 10.0 to obtain the results; after the results were visualized using von Mises stress maps and Maximum stress principal. The results showed the stress distribution was similar between models, with a little superiority of Morse-taper connection. It was concluded that: the three connection types were biomechanical viable; The Morse-taper connection presented the better internal stress distribution; there was not significant biomechanical differences on the bone.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Las discrepancias entre las funciones de distribución acumulada de la tensión de fractura del vidrio es una de las dificultades encontradas para incorporar la filosofía probabilista para el diseño del vidrio. Se utilizan tres ensayos para la caracterización de la tensión de fractura del vidrio: flexión de viga en cuatro puntos, ensayo con dobles anillos concéntricos con pequeña superficie y con gran superficie. La comparación directa de las funciones de distribución presenta discrepancias claras relacionadas con el estado de tensión -uni o biaxial- y con el comportamiento de la estructura -grandes o pequeños desplazamientos. Con un procedimiento iterativo, se ajustan los resultados de los ensayos (carga - presión- probabilidad de rotura) a través de un modelo de elementos finitos que permite estimar las aéreas efectivas de cada espécimen. Los parámetros finales para la tensión de rotura mejoran la estimación de la probabilidad de la carga de rotura de cada probeta con errores inferiores al 10%.
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Mode of access: Internet.
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Dissertação (mestrado)—Universidade de Brasília, Faculdade de Tecnologia, Departamento de Engenharia Civil e Ambiental, 2015.