Presta????o de contas ordin??ria anual: relat??rio de gest??o do exerc??cio de 2009

Apresenta as a????es realizadas pela Escola inserem-se no Programa Desenvolvimento de Compet??ncias em Gest??o P??blica e, nesse sentido, foram desenvolvidas e oferecidas diversas oportunidades de capacita????o aos servidores, como cursos de curta e longa dura????o para gerentes; cursos presenciais e a dist??ncia; cursos e eventos internacionais orientados para quadros estrat??gicos; cursos de forma????o e aperfei??oamento de carreiras; especializa????es; semin??rios e oficinas; al??m da realiza????o de pesquisas e eventos com o intuito de inovar e irradiar boas pr??ticas na Administra????o P??blica

Presta????o de contas ordin??ria anual: relat??rio de gest??o do exerc??cio de 2010

Relat??rio de Gest??o do exerc??cio de 2010 apresentado aos ??rg??os de controle interno e externo como presta????o de contas anual que a ENAP est?? obrigada nos termos do art. 70 da Constitui????o Federal, elaborado de acordo com as disposi????es da IN TCU n?? 63/2010, da DN TCU n?? 107/2010, da Portaria TCU n?? 277/2010 e das orienta????es do ??rg??o de controle interno (Portaria CGU n?? 2546/2010)

Relat??rio de gest??o do exerc??cio de 2012

Relat??rio de Gest??o do exerc??cio de 2012 apresentado aos ??rg??os de controle interno e externo como presta????o de contas anual a que esta Unidade est?? obrigada nos termos do art. 70 da Constitui????o Federal, elaborado de acordo com as disposi????es da IN TCU n?? 63/2010, da DN TCU n?? 119/2012, da Portaria TCU n?? 150/2012 e das orienta????es do ??rg??o de controle interno (Portaria CGU n?? 133/2013)

Relat??rio de gest??o do exerc??cio de 2013

Relat??rio de Gest??o do exerc??cio de 2013 apresentado aos ??rg??os de controle interno e externo como presta????o de contas anual a que esta Unidade est?? obrigada nos termos do art. 70 da Constitui????o Federal, elaborado de acordo com as disposi????es da IN TCU n?? 63/2010, da DN TCU n?? 127/2013, da Portaria TCU n?? 175/2013 e das orienta????es do ??rg??o de controle interno (Portaria CGU n?? 133/2013)

Transpar??ncia, monitoramento e avalia????o de programas no Brasil: em busca de opacidades que podem restringir o exerc??cio do controle social

A nova lei brasileira de acesso ?? informa????o estabeleceu um conjunto de defini????es, princ??pios e diretrizes voltado ?? promo????o da transpar??ncia e ?? viabiliza????o do exerc??cio do controle social sobre a a????o governamental. Segundo esta lei, os resultados dos programas do Plano Plurianual (PPA) fazem parte do conjunto de informa????es que precisam ser franqueadas aos cidad??os. Tais resultados s??o gerados a partir das regras da sistem??tica de monitoramento e avalia????o de programas que deve ser estabelecida no pr??prio PPA. Este trabalho objetiva analisar a ader??ncia desta sistem??tica ?? lei de acesso ?? informa????o, com a finalidade de suscitar o debate sobre a exist??ncia de certas opacidades que podem restringir o acompanhamento e a avalia????o da a????o governamental pela sociedade

Resolu????o n?? 05, de 24 de setembro de 2010: disciplina o incentivo de servidores em exerc??cio na ENAP para participar dos cursos de especializa????o oferecidos pela Escola

A Resolu????o n?? 5, de 24 de setembro de 2010 disciplina o incentivo de servidores em exerc??cio na ENAP para participar dos cursos de especializa????o oferecidos pela Escola. Adicionalmente, s??o publicados editais espec??ficos para a sele????o de servidores para o Programa de Capacita????o em Idiomas, na ocasi??o de disponibilidade de vagas.

(Arrêt du grand conseil, qui condam ne les y dénommés à accepter le retrait exercé par le P. recteur du collège Louis de Grand de baux aliénés.)

[Acte. 1714-02-15. Paris]

Exerc[itati]o XXXXV : I. Qua cura atte[n]tus generosusq[ue] medicus uti debeat in variolaru[m] partiu[m] oris praeservatione curationeq[ue] ... 2. Lentis alterum decoctum multiplex priscumque auxilium esse ... 3. Praesentibus variolis clysteribus lenientibus praecipue opus esse .../

Mode of access: Internet.

Acute Exercise Decreases Trb3 Protein Levels In The Hypothalamus Of Obese Rats.

To evaluate the effects of acute exercise on the TRB3 protein levels and interaction between TRB3/Akt proteins in the hypothalamus of obese rats. In addition, we evaluated the relationship between TRB3 and endoplasmic reticulum stress (ER stress) and verified whether an acute exercise session is able to influence these processes. In the first part of the study, the rats were divided into three groups: control (lean) - fed with a standard rodent chow, DIO - fed with a high fat diet and DIO submitted to a swimming acute exercise protocol (DIO-EXE). In the second part of the study, we used other three groups: control (lean) receiving an intracerebroventricular (i.c.v.) infusion of vehicle, lean receiving an i.c.v. infusion of thapsigargin, and lean receiving an i.c.v infusion of thapsigargin and performing an acute exercise session. Four hours after the exercise session, the food intake was measured and the hypothalamus was dissected and separated for subsequent protein analysis by immunoblotting and Real Time PCR. The acute exercise session reduced the TRB3 protein levels, disrupted the interaction between TRB3/Akt proteins, increased the phosphorylation of Foxo1 and restored the anorexigenic effects of insulin in the hypothalamus of DIO rats. Interestingly, the suppressive effects of acute exercise on TRB3 protein levels may be related, at least in part, to the decrease of ER stress (evaluated though pancreatic ER kinase phosphorylation - pPERK and C/EBP homologous protein - CHOP protein levels) in the hypothalamus. In conclusion, the reduction of hypothalamic TRB3 protein levels mediated by exercise may be associated with the reduction of ER stress. These data provided a new mechanism by which an acute exercise session improves insulin sensitivity in hypothalamus and restores food intake control in obesity.

Resistance Training with Vascular Occlusion in Inclusion Body Myositis: A Case Study

GUALANO, B., M. NEVES JR, F. R. LIMA, A. L. PINTO, G. LAURENTINO, C. BORGES, L. BAPTISTA, G. G. ARTIOLI, M. S. AOKI, A. MORISCOT, A. H. LANCHA JR, E. BONFA, and C. UGRINOWITSCH. Resistance Training with Vascular Occlusion in Inclusion Body Myositis: A Case Study. Med Sci. Spot-is Exerc., Vol. 42, No. 2, pp. 250-254, 2010. Inclusion body myositis (IBM) is a rare idiopathic inflammatory myopathy that produces remarkable muscle weakness. Resistance training with vascular occlusion has been shown to improve muscle strength and cross-sectional area in other muscle wasting conditions. Purpose: We evaluated the efficacy of a moderate-intensity resistance training program combined with vascular occlusion by examining functional capacity, muscle morphology, and changes in the expression of genes related to muscle protein synthesis and proteolysis in a patient with IBM. Methods: A 65-yr-old man with IBM resistant to all proposed treatments underwent resistance training with vascular occlusion for 12 wk. Leg press one-repetition maximum; thigh cross-sectional area; balance, mobility, and muscle function; quality of life; and blood markers of inflammation and muscle damage were assessed at baseline and after the 12-wk program. The messenger RNA (mRNA) expression levels of mechanogrowth factor, mammalian target of rapamycin, atrogin-1, and muscle RING finger-1 were also quantified. Results: After the 12-wk training program, the patient`s leg press one-repetition maximum, balance and mobility function, and thigh cross-sectional area increased 15.9%, 60%, and 4.7%, respectively. All Short Form-36 Health Survey Questionnaire subscales demonstrated improvements as well, varying from 18% to 600%. mRNA expression of mechanogrowth factor increased 3.97-fold, whereas that of atrogin-1 decreased 0.62-fold. Muscle RING finger-1 and mammalian target of rapamycin mRNA levels were only slightly altered, 1.18- and 1.28-fold, respectively. Importantly, the exercise did not induce disease flare. Conclusions: We describe a novel, and likely the first, nonpharmacological therapeutic tool that might be able to counteract the muscle atrophy and the declining strength that usually occur in IBM.

Anabolic steroid associated to physical training induces deleterious cardiac effects

DO CARMO, E. C., T. FERNANDES, D. KOIKE, N. D. DA SILVA JR., K. C. MATTOS, K. T. ROSA, D. BARRETTI, S. F. S. MELO, R. B. WICHI, M. C. C. IRIGOYEN, and E. M. DE OLIVEIRA. Anabolic Steroid Associated to Physical Training Induces Deleterious Cardiac Effects. Med. Sci. Sports Exerc., Vol. 43, No. 10, pp. 1836-1848, 2011. Purpose: Cardiac aldosterone might be involved in the deleterious effects of nandrolone decanoate (ND) on the heart. Therefore, we investigated the involvement of cardiac aldosterone, by the pharmacological block of AT1 or mineralocorticoid receptors, on cardiac hypertrophy and fibrosis. Methods: Male Wistar rats were randomized into eight groups (n = 14 per group): Control (C), nandrolone decanoate (ND), trained (T), trained ND (TND), ND + losartan (ND + L), trained ND + losartan (TND + L), ND + spironolactone (ND + S), and trained ND + spironolactone (TND + S). ND (10 mg.kg(-1).wk(-1)) was administered during 10 wk of swimming training (five times per week). Losartan (20 mg.kg(-1).d(-1)) and spironolactone (10 mg.kg(-1).d(-1)) were administered in drinking water. Results: Cardiac hypertrophy was increased 10% by using ND and 17% by ND plus training (P < 0.05). In both groups, there was an increase in the collagen volumetric fraction (CVF) and cardiac collagen type III expression (P < 0.05). The ND treatment increased left ventricle-angiotensin-converting enzyme I activity, AT1 receptor expression, aldosterone synthase (CYP11B2), and 11-beta hydroxysteroid dehydrogenase 2 (11 beta-HSD2) gene expression and inflammatory markers, TGF beta and osteopontin. Both losartan and spironolactone inhibited the increase of CVF and collagen type III. In addition, both treatments inhibited the increase in left ventricle-angiotensin-converting enzyme I activity, CYP11B2, 11 beta-HSD2, TGF beta, and osteopontin induced by the ND treatment. Conclusions: We believe this is the first study to show the effects of ND on cardiac aldosterone. Our results suggest that these effects may be associated to TGF beta and osteopontin. Thus, we conclude that the cardiac aldosterone has an important role on the deleterious effects on the heart induced by ND.

Role of beta-alanine supplementation on muscle carnosine and exercise performance

ARTIOLI, G. G., B. GUALANO, A. SMITH, J. STOUT, and A. H. LANCHA, JR. Role of beta-Alanine Supplementation on Muscle Carnosine and Exercise Performance. Med. Sci. Sports Exerc., Vol. 42, No. 6, pp. 1162-1173, 2010. In this narrative review, we present and discuss the current knowledge available on carnosine and beta-alanine metabolism as well as the effects of beta-alanine supplementation on exercise performance. Intramuscular acidosis has been attributed to be one of the main causes of fatigue during intense exercise. Carnosine has been shown to play a significant role in muscle pH regulation. Carnosine is synthesized in skeletal muscle from the amino acids L-histidine and beta-alanine. The rate-limiting factor of carnosine synthesis is beta-alanine availability. Supplementation with beta-alanine has been shown to increase muscle carnosine content and therefore total muscle buffer capacity, with the potential to elicit improvements in physical performance during high-intensity exercise. Studies on beta-alanine supplementation and exercise performance have demonstrated improvements in performance during multiple bouts of high-intensity exercise and in single bouts of exercise lasting more than 60 s. Similarly, beta-alanine supplementation has been shown to delay the onset of neuromuscular fatigue. Although beta-alanine does not improve maximal strength or (V) over dotO(2max), some aspects of endurance performance, such as anaerobic threshold and time to exhaustion, can be enhanced. Symptoms of paresthesia may be observed if a single dose higher than 800 mg is ingested. The symptoms, however, are transient and related to the increase in plasma concentration. They can be prevented by using controlled release capsules and smaller dosing strategies. No important side effect was related to the use of this amino acid so far. In conclusion, beta-alanine supplementation seems to be a safe nutritional strategy capable of improving high-intensity anaerobic performance.

Prevalence, magnitude, and methods of rapid weight loss among judo competitors

ARTIOLI, G. G., B. GUALANO, E. FRANCHINI, F. B. SCAGLIUSI, M. TAKESIAN, M. FUCHS, and A. H. LANCHA. Prevalence, Magnitude, and Methods of Rapid Weight Loss among Judo Competitors. Med. Sci. Sports Exerc., Vol. 42, No. 3, pp. 436-442, 2010. Purpose: To identify the prevalence, magnitude, and methods of rapid weight loss among judo competitors. Methods: Athletes (607 males and 215 females; age = 19.3 +/- 5.3 yr, weight = 70 +/- 7.5 kg, height = 170.6 +/- 9.8 cm) completed a previously validated questionnaire developed to evaluate rapid weight loss in judo athletes, which provides a score. The higher the score obtained, the more aggressive the weight loss behaviors. Data were analyzed using descriptive statistics and frequency analyses. Mean scores obtained in the questionnaire were used to compare specific groups of athletes using, when appropriate, Mann-Whitney U-test or general linear model one-way ANOVA followed by Tamhane post hoc test. Results: Eighty-six percent of athletes reported that have already lost weight to compete. When heavyweights are excluded, this percentage rises to 89%. Most athletes reported reductions of up to 5% of body weight (mean +/- SD: 2.5 +/- 2.3%). The most weight ever lost was 2%-5%, whereas a great part of athletes reported reductions of 5%-10% (mean +/- SD: 6 +/- 4%). The number of reductions underwent in a season was 3 +/- 5. The reductions usually occurred within 7 +/- 7 d. Athletes began cutting weight at 12.6 +/- 6.1 yr. No significant differences were found in the score obtained by male versus female athletes as well as by athletes from different weight classes. Elite athletes scored significantly higher in the questionnaire than nonelite. Athletes who began cutting weight earlier also scored higher than those who began later. Conclusions: Rapid weight loss is highly prevalent in judo competitors. The level of aggressiveness in weight management behaviors seems to not be influenced by the gender or by the weight class, but it seems to be influenced by competitive level and by the age at which athletes began cutting weight.