912 resultados para Drugs -- Environmental aspects


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Introduction Visceral leishmaniasis (VL) stands out as a zoonosis observed on four continents and also in urban expansion zones in several regions of Brazil. Methods A cross-sectional epidemiological study of VL cases in children under 15 years of age in the period from 2007 to 2012. Clinical data were gathered from medical reports; meteorological data were obtained at the Meteorological Measurement Department of UFT. Environmental variables were divided into two periods, rainy and dry. Results The study revealed no difference by gender (p=0.67) among the 821 patients. However, the most affected age group was between one and five years of age (58.6%; p<0.01); the highest prevalence of the disease (99.03%; p<0.01) occurred in urban zones; and the most affected ethnic group (85.5%; p<0.01) was mixed race. The highest incidence coefficients in this population occurred in 2007 and 2008 (578.39/100,000 inhabitants; 18.5/100,000 inhabitants, respectively), whereas the highest lethality coefficients occurred in 2008 and 2011 (0.85/100 deaths). There was no significant correlation between average rainfall and the number of VL cases. The correlation between temperature and number of VL cases was negative (r = -0.4039; p<0.01). Conclusions In Aragua&#237;na, visceral leishmaniasis in children under 15 years is an urban-based endemic disease distributed across all districts of the city wherein temperature as an environmental factor, a higher prevalence in mixed race children between one and five years of age, and a high incidence coefficient all strongly contribute to child mortality.

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Tyn tavoite onharmonisoida yhteniset rakenteet UPM:n paperi- ja sellutehtaiden merkittvilleympristnkkohdille sek niiden ympristriskienhallintajrjestelmille. Nin saavutetaan yhteneviset tavoitteet ja analysointikeinot yrityksen yksikille. Harmonisointiprosessi on osa koko yrityksen ympristhallintajrjestelmn kehittmist. Ja konsernin EMS -prosessi puolestaan konvergoi konsernin integroidun johtamisjrjestelmn kehityst. Lisksi tyn tapaustutkimuksessa selvitettiin riskienhallintajrjestelmien integroitumispotentiaalia. Sen avulla saavutettaisiin paremmin suuren yrityksen synergia-etuja ja vuorovaikutteisuutta toimijoiden kesken, sek parannettaisiin riskienhallintajrjestelmn mukautuvuutta ja kytettvyytt. Tyss ksitelln kolmea esimerkki, joiden pohjalta tehdn esitys harmonisoiduille merkittville ympristnkkohdille sek riskienhallintajrjestelmien parametreille. Tutkimusongelmaa lhestytn haastattelujen, kirjallisuuden, yrityksen PWC:ll teettmn selvityksen sek omien ptelmien avulla. Lisksi tyss esitetn ympristhallintajrjestelmn tehokkuuden todentaminen ympristsuorituskyvyn muuttujiin suhteutettuna. Pohjana jatkuvan kehityksen pmrlle on organisaatio-oppiminen, niin yksittisen tyntekijn, tiimien kuin eri yksikiden kesken. Se antaa sysyksen aineettoman omaisuuden, kuten ymprist-osaamisen, hydyntmiseen parhaalla mahdollisella tavalla. Trkeimpin lopputuloksina tyss ovat ehdotukset harmonisoiduille merkittville ympristnkkohdille sek ympristriskienhallintajrjestelmn mritetyille komponenteille. Niit ovat mritelmt ja skaalat riskien todennkisyydelle, seurauksille sek riskiluokille. Tyn viimeisen osana luodaan pohja tapaustutkimuksen avulla Rauman tehtaan jtevedenpuhdistamon kahden erilaisen riskienhallintajrjestelmn integroitumiselle.

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Various regulations and customer requirements have made it necessary for Vacon Oyj to pay more attention to the environmental aspects in its processes. The main purpose of this masters thesis project is to define how environmental aspects could be integrated into Vacons product development process. The aim is to find out the most important environmental aspects for the company to address, to examine how these could be taken into account during the development process and to map the critical factors that need consideration in order to ensure the successful integration of environmental aspects into the design process. Based on the customer requirements and evolving regulations the most important aspects for Vacon include minimizing the amount of harmful substances, improving the recyclability and energy efficiency of the product and moreover providing meaningful information related to these aspects. To tackle these issues, a new DfE process was developed, tasks in each phase were described and responsibilities were indicated. To ensure the success of the DfE process, management commitment, support of other processes and significant improvements in ways the information is managed are required. The developers should be provided with training and support. Environmental expertise and knowledge in-house should be developed and establishing meaningful environmental indicators is suggested.

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Bibliography: p. 19-21.

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Pt. 2 has subtitle: Hearings before the Committee on Energy and Natural Resources, United States Senate, One Hundredth Congress, first session, on the status of the Department of Energy's effects to address issues concerning the defense materials production reactors ... October 27 and 29, 1987.

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La reutilizacin de las aguas residuales es una parte esencial del uso sostenible del agua. Sin embargo, las actuales plantas de tratamiento no estn preparadas para tratar determinados compuestos como los llamados contaminantes emergentes. Los hbitos de consumo actuales estan generando una serie de residuos o microcontaminantes que hace tan solo unos aos no existian. Entre esas nuevas sustancias aparecen los PPCPs (Pharmaceuticals & Personal Care Products) que son un amplio grupo de compuestos qumicos utilizados en veterinaria, prcticas agrcolas, salut humana y cosmetologa. El mayor problema que presentan estas substancias en la actualidad es el parcial desconocimiento sobre sus efectos, la ausencia de reglamentaciones que determinen las concentraciones mximas admisibles en los cauces de vertido, la reduccin en procesos de depuracin convencionales, as como los tratamientos especficos aplicables a su eliminacin. Los objetivos del presente proyecto sn: estudiar las tipologas de PPCPs y sus influencias para la salud humana y el medio ambiente, estudiar los diferentes sistemas de tratamiento de aguas existentes en plantas depuradoras y evaluar su eficiencia en la depuracin de PPCP

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La reutilizacin de las aguas residuales es una parte esencial del uso sostenible del agua. Sin embargo, las actuales plantas de tratamiento no estn preparadas para tratar determinados compuestos como los llamados contaminantes emergentes. Los hbitos de consumo actuales estan generando una serie de residuos o microcontaminantes que hace tan solo unos aos no existian. Entre esas nuevas sustancias aparecen los PPCPs (Pharmaceuticals & Personal Care Products) que son un amplio grupo de compuestos qumicos utilizados en veterinaria, prcticas agrcolas, salut humana y cosmetologa. El mayor problema que presentan estas substancias en la actualidad es el parcial desconocimiento sobre sus efectos, la ausencia de reglamentaciones que determinen las concentraciones mximas admisibles en los cauces de vertido, la reduccin en procesos de depuracin convencionales, as como los tratamientos especficos aplicables a su eliminacin. Los objetivos del presente proyecto sn: estudiar las tipologas de PPCPs y sus influencias para la salud humana y el medio ambiente, estudiar los diferentes sistemas de tratamiento de aguas existentes en plantas depuradoras y evaluar su eficiencia en la depuracin de PPCP

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This article aims to analyse the introduction of environmental issues in the context of the production function, which has been referred to as the organisational area to lead corporate environmental management. With that purpose, the theoretical references for corporate environmental management and the necessary alterations in production function have been organised to include environmental aspects, especially in terms of product and process development, quality management, and logistics. Considering that this research field still lacks empirical evidence for Brazilian companies, four case studies were conducted using companies located in the country. The environmental management maturity level of those companies tends to follow the rate with which the environmental issue is introduced in production sub-areas, especially in the product development process. However, in most cases we found that the companies had difficulties in structuring the insertion of the environmental dimension in logistics. The final notes point out the distance observed between what is recommended by international literature and the reality of Brazilian companies in the challenge of making the production function environmentally friendly.