976 resultados para Keisarillinen Aleksanterin yliopisto - Faculty
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Kirjallisuusarvostelu
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Tiivistelmä Tekijä: Antti Korkki Tutkielman nimi: Hiljaisen tiedon siirtäminen Palveluyritys Oy:n Helsingin myyntiosastolla myyntipäällikön näkökulmasta Tiedekunta: Kauppatieteellinen tiedekunta Maisteriohjelma: Tietojohtaminen Vuosi: 2014 Pro gradu –tutkielma: Lappeenrannan teknillinen yliopisto 88 sivua, 20 kuvaa ja yksi taulukko Tarkastajat: Professori Markku Ikävalko Tutkijatohtori Anna-Maija Nisula Hakusanat: Hiljainen tieto, tiedon jakaminen ja osaaminen Kiristynyt kilpailutilanne kuljetusalalla pakottaa alan yritykset etsimään uusia keinoja strategisen kilpailuedun saavuttamiseksi. Palvelualan yritykselle merkittävin kilpailukeino on palvelun laadulla kilpaileminen ja korkean laadun saavuttamiseksi on tärkeää, että oikea tieto on oikeassa paikassa oikeaan aikaan. Tämä tarkoittaa käytännössä reaaliaikaisten tiedon siirtämisen menetelmien käyttämistä. Tämän tutkimuksen tarkoituksena on selvittää Palveluyritys Oy:n Helsingin myyntiosaston tiedon siirtämisen foorumien nykytilanne myyntipäällikön näkökulmasta. Lisäksi tutkimuksella etsitään keinoja tehostaa hiljaisen tiedon siirtämistä Palveluyritys Oy:n Helsingin myyntiosastolla. Tutkimuksessa käytetään laadullista tutkimusmenetelmää ja teoriaohjaavaa sisällön analyysiä.
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Tekijä: Eino Leino.
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University of Turku, Faculty of Medicine, Department of Clinical Medicine, Department of Physical Activity and Health, Paavo Nurmi Centre, Doctoral Programme of Clinical Investigation, University of Turku, Turku, Finland. Annales Universitatis Turkuensis. Medica – Odontologica, Turku, Finland, 2014. Background: Atherosclerosis progression spans an entire lifetime and has a wide pool of risk factors. Oxidized LDL (oxLDL) is a crucial element in the progression of atherosclerosis. As a rather new member in the atherosclerosis risk factor family, its interaction with the traditional pro-atherogenic contributors that occur at different ages is poorly known. Aims: The aim of this study was to investigate oxLDL and its relation to major contributing risk factors in estimating atherosclerosis risk in data consisting mostly of adult men. The study subjects of this study consisted of four different sets of data, one of which contained also women. The age range of participants was 18-100 years and totaled 2337 participants (of whom 69% were men). Data on anthropometric and hormonal parameters, laboratory measures and medical records were assessed during 1998-2009. Results: Obesity was paralleled with high concentrations of oxLDL, which consequentially was reduced by weight reduction. Importantly, successful weight maintenance preserveed this benefit. A shift from insulin sensitivity to insulin resistance increased oxLDL. Smokers had more oxLDL than non-smokers. A combination of obesity and smoking, or smoking and low serum total testosterone,resulted in even higher levels of oxLDL than any of the three conditions alone. Proportioning oxLDL to HDL-c or apoA1 stood out as a risk factor of all-cause mortality in the elderly. Conclusions: OxLDL was associated with aging, androgens, smoking, obesity, insulin metabolism, weight balance and other circulating lipid classes. Through this variety of metabolic environments containing both constant conditions (aging and gender) as well as lifestyle issues, these findings supported an essential and multidimensional role that oxLDL plays in atherosclerosis pathogenesis.
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TIIVISTELMÄ Lappeenrannan teknillinen yliopisto Teknillinen tiedekunta Konetekniikan koulutusohjelma Sami Suvanto Kuorimarummun kantokehän ja lohkon valmistuksen ja vaihdon kriittiset menestystekijät. Diplomityö 2014 64 sivua, 16 kuvaa, 5 taulukkoa, 1 liite Tarkastajat: Professori Jukka Martikainen DI Jari Junninen Hakusanat: kuorimo, kuorimarumpu, kantokehä, vaippalohko, hitsaus Keywords: wood room, debarking drum, support ring, drum shell, welding Sellutehtaiden puunkäsittelylaitoksilla kuorimarumpu on yksi tärkeimmistä prosessilaitteista. Kuorimarummun kantokehän tai lohkon vaihto on tyypillisesti koko puunkäsittelyn elinkaaren merkittävin korjausinvestointi. Markkinoilla on muutamia laitevalmistajia, jotka kilpailevat omien, sekä kilpailijoiden kuorimarumpujen korjausurakoista. Tässä diplomityössä selvitetään kuorimarummun kantokehän ja lohkonvaihtourakoiden kriittiset menestystekijät. Selvitys tehdään arvioimalla tekninen konstruktio, vaihtomenetelmät, sekä toimintamalli vaihtoprojektin suorittamisessa. Case tutkimukseen valittiin yksi kilpailijalle hävitty vaippalohkon vaihtotarjous, yksi kilpailijalle hävitty kantokehän vaihtotarjous, sekä yksi kantokehätoimitus. Työn tuloksena vahvuudet ja heikkoudet kuorimarummun kunnossapidossa tulivat esiin. Työn aikana löydettiin myös lukuisia kehitysideoita. Näitä ideoita viedään eteenpäin normaalina kehitystyönä.
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TIIVISTELMÄ Tekijä: Urpalainen, Mika Tutkielman nimi: Miten kehittää ketjuliiketoimintaa rautakaupassa Case: Rautanet Tiedekunta: Kauppatieteellinen tiedekunta Pääaine / Maisteriohjelma: Kansainvälinen markkinointi Vuosi: 2014 Pro gradu – tutkielma: Lappeenrannan teknillinen yliopisto, 129 sivua, 28 kuvaa, 15 taulukkoa ja kaksi liitettä Tarkastajat: prof. Olli Kuivalainen, prof. Sanna-Katriina Asikainen Hakusanat: ketjutoiminta, Rautanet-ketju, sitoutuminen, markkinointi Keywords: Chain business, Rautanet-chain, commitment, marketing Rautanet-ketju on heterogeeninen, vapaaehtoisuuteen perustuva rautakauppaketju, joka on perustettu vuonna 1998. Tämän tutkimuksen tarkoituksena on selvittää Rautanet-kauppiaille ja koko ketjuorganisaatiolle ketjutoiminnan etuja, haasteita sekä kauppiaskunnan näkemyksiä ketjutoiminnasta tänä päivänä. Tutkimusmenetelmä oli kvalitatiivinen ja kvantitatiivinen, se perustui kauppiaille lähetettyyn kyselylomakkeeseen, joka sisälsi Likert-asteikollisia kysymyksiä 36 ja 3 kysymystä joihin vastattiin kirjallisesti. Kysymykset sisälsivät aiheita mm. Sitoutumisesta, markkinoinnista, sidosryhmistä jne. Tutkimusjoukkona oli Rautanet-kauppiaat. Kokonaisuutena arvioiden kauppiaat ovat tyytyväisiä ketjun toimintaan. Suurimmat edut ovat markkinointituki kuvastojen avulla ja ketjun voima, jonka kauppiaat tekevät yhdessä. Etuna voidaan pitää myös kauppiaiden sitoutumishalukkuutta ketjuun. Suurimpana haasteena on ehkä itsenäisyyden menettämisen pelko. Rautanet-ketjun toiminta on hyvällä tasolla. Kilpailun kiristyessä myös Rautanet-ketjun kauppiaiden sitoutumishalukkuutta on pidettävä yllä. Ketjuorganisaation on kunnioitettava kauppiaan itsenäisyyttä ja kuunneltava jatkossakin kauppiaita. Ketjun ja kauppiaiden selkeä yhteinen päämäärä, rakentaa vahva ketju, joka pystyy vastaamaan kilpailijoiden haasteisiin, on hyvin paljon riippuvainen yhdessä tekemisen halusta.
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Kirjallisuusarvostelu
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TIIVISTELMÄ Lappeenrannan teknillinen yliopisto Teknistaloudellinen tiedekunta Tuotantotalouden koulutusohjelma Seppo Kuittinen Teollinen Internet uuden liiketoiminnan katalysaattorina Case CGI Diplomityö 2015 78 sivua, 33 kuvaa, 1 taulukko, 1 liite Työn tarkastajat: Professori Timo Pihkala Tutkijatohtori Marita Rautiainen Hakusanat: teollinen internet, IoT, kehittynyt analytiikka, sensorit Keywords: Industrial internet, IoT, advanced analytics, sencors Tämän työn tarkoituksena on tutkia asiakaskyselyn avulla luoko teollinen internet case yritykselle uutta ohjelmisto- tai palveluliiketoimintaa. Case yritys valitsi omasta asiakaskunnastaan 15 kohdeasiakasta, joille kysely lähetettiin. Vastauksista käy ilmi, että asiakaskunnassa on näkemys siitä, mitä teollinen internet on. Nykyisten ratkaisujen ei nähdä ratkaisevan kaikkia teollisen internetin mukanaan tuomia ongelmia. Ongelmaksi koetaan sensoridatan analysointi, jonka ei vielä katsota olevan riittävän kehittynyttä ja luotettavaa. Kyselystä voidaan päätellä, ettei mitään räjähtävää kasvua ole odotettavissa lähiaikoina. Teollinen internet tulee olemaan osa yritysten liiketoimintaa, mutta sen käyttö laajenee pikkuhiljaa.
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Tutkimuksessa selvitettiin yliopisto-opettajien, luokanopettajaopiskelijoiden ja yleisen kasvatustieteen opiskelijoiden kokemuksia opiskelijoiden aktivoivilla luennoilla esittämien puheenvuorojen merkityksestä opiskelijoiden oppimiseen tieteellisten argumentoinnin taitojen sekä oppimisen reflektoinnin harjaantumisen ja opettajan opetuksen kehittämisen kautta. Lisäksi tarkasteltiin opettajien ja opiskelijoiden kokemuksia siitä, pystyivätkö opiskelijat luennoilla vaikuttamaan tieteen kehitykseen, ja onko puheenvuoroilla yhteyttä opiskelijoiden sosiaalisen riippuvusorientaation vahvistumiseen. Tutkittavat olivat Turun yliopiston opettajia ja opiskelijoita (N = 237). Tutkittavien kokemuksia kartoitettiin kyselylomakkeen avulla. Lomake sisälsi 21 väittämää opiskelijoiden luennoilla esittämistä puheenvuoroista. Tutkimuksen mukaan sekä opettajat että opiskelijat näkivät opiskelijoiden luennoilla esittämien puheenvuorojen lisäävän opettajan mahdollisuutta kehittää opetustaan sekä opiskelijan mahdollisuutta vahvistaa tieteellisen argumentoinnin taitojaan ja oppimansa reflektointia. Opettajat uskoivat puheenvuorojen tuomiin mahdollisuuksiin opiskelijoita voimakkaammin. Lisäksi opettajat kokivat opiskelijoiden puheenvuorojen suuntaavan opiskelijan toimintaa oppimisesta opettajan sosiaaliseen miellyttämiseen. Tulokset osoittivat, että aktivoivalla luento-opetuksella koettiin olevan positiivisia vaikutuksia opiskelijoiden oppimiseen. Yliopisto-opettajien ja -opiskelijoiden tiedostaessa aktivoivan luento-opetuksen hyödyt, voidaankin pohtia, tulisiko aktivoivan luento-opetuksen yleistyä korkeakouluissa.
Improving oral healthcare in Scotland with special reference to sustainability and caries prevention
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Brett Duane Improving oral healthcare in Scotland with special reference to sustainability and caries prevention University of Turku, Faculty of Medicine, Institute of Dentistry, Community Dentistry, Finnish Doctoral Program in Oral Sciences (FINDOS-Turku), Turku, Finland Annales Universitatis Turkuensis, Sarja- Ser. D, Medica-Odontologica. Painosalama Oy, Turku, Finland, 2015. Dentistry must provide sustainable, evidence-based, and prevention-focused care. In Scotland oral health prevention is delivered through the Childsmile programme, with an increasing use of high concentration fluoride toothpaste (HCFT). Compared with other countries there is little knowledge of xylitol prevention. The UK government has set strict carbon emission limits with which all national health services (NHS) must comply. The purpose of these studies was firstly to describe the Scottish national oral health prevention programme Childsmile (CS), to determine if the additional maternal use of xylitol (CS+X) was more effective at affecting the early colonisation of mutans streptococci (MS) than this programme alone; secondly to analyse trends in the prescribing and management of HCFT by dentists; and thirdly to analyse data from a dental service in order to improve its sustainability. In all, 182 mother/child pairs were selected on the basis of high maternal MS levels. Motherswere randomly allocated to a CS or CS+X group, with both groups receiving Childsmile. Theintervention group consumed xylitol three times a day, from when the child was 3 months until 24 months. Children were examined at age two to assess MS levels. In order to understand patterns of HCFT prescribing, a retrospective secondary data analysis of routine prescribing data for the years 2006-2012 was performed. To understand the sustainability of dental services, carbon accounting combined a top-down approach and a process analysis approach, followed by the use of Pollard’s decision model (used in other healthcare areas) to analyse and support sustainable service reconfiguration. Of the CS children, 17% were colonised with MS, compared with 5% of the CS+X group. This difference was not statistically significant (P=0.1744). The cost of HCFT prescribing increased fourteen-fold over five years, with 4% of dentists prescribing 70% of the total product. Travel (45%), procurement (36%) and building energy (18%) all contributed to the 1800 tonnes of carbon emissions produced by the service, around 4% of total NHS emissions. Using the analytical model, clinic utilisation rates improved by 56% and patient travel halved significantly reducing carbon emissions. It can be concluded that the Childsmile programme was effective in reducing the risk for MS transmission. HCFT is increasing in Scotland and needs to be managed. Dentistry has similar carbon emissions proportionally as the overall NHS, and the use of an analytic tool can be useful in helping identify these emissions. Key words: Sustainability, carbon emissions, xylitol, mutans streptococci, fluoride toothpaste, caries prevention.
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Aino Toiviainen Probiotics and oral health: in vitro and clinical studies University of Turku, Faculty of Medicine, Institute of Dentistry, Periodontology, Finnish Doctoral Program in Oral Sciences (FINDOS-Turku), Turku, Finland Annales Universitatis Turkuensis, Sarja – Ser. D, Medica-Odontologica. Painosalama Oy, Turku, Finland, 2015 Probiotics are used, for example, to prevent and treat diarrhea, allergies and respiratory infections, and there is an increasing interest to use probiotics also for oral health purposes. The most commonly used probiotic bacteria are lactobacilli and bifidobacteria, which are acidogenic and aciduric. From the oral point of view, use of these probiotics may, at least in theory, mean an increased risk of caries. In this thesis, the effects of probiotics on oral microbial composition, acid production of dental plaque and gingival health were studied through in vitro studies and two clinical studies. In a randomized, double-blind and crossover study, 13 healthy adults were allocated into two groups. Half of the subjects first consumed Lactobacillus rhamnosus GG tablets twice a day for two weeks, and after the washout period, L. reuteri tablets twice a day for two weeks. The other half of the subjects used the tablets in reverse order. In another controlled, randomized and double-blind study, 62 healthy adults were allocated into two groups. One group used the test tablets containing L. rhamnosus GG and B. lactis BB-12 and the other group used control tablets without probiotics. The recommendation for the use of the tablets was 4 per day for 4 weeks. Probiotic lactobacilli interfered with S. mutans biofilm formation and the adhesion of S. mutans to saliva-coated hydroxyapatite in vitro. No effect was found in S. mutans levels in the three-species biofilms. In clinical studies, the studied probiotics had no effect on the acid production of plaque. The counts of mutans streptococci and the oral microbial composition remained the same. Tablets containing L. rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 did decrease the amount of plaque and gingival bleeding. According to our results, it seems that probiotics have beneficial effects on gingival health. The present results confirmed that probiotics are safe and have beneficial effects on oral health. Since the consumption of probiotics by the general population is steadily increasing, an understanding of the functions of probiotics in the oral cavity has become more important. Keywords: lactobacilli, bifidobacteria, caries, periodontal disease, mutans streptococci, probiotics
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Genetic, Prenatal and Postnatal Determinants of Weight Gain and Obesity in Young Children – The STEPS Study University of Turku, Faculty of Medicine, Department of Paediatrics, University of Turku Doctoral Program of Clinical Investigation (CLIPD), Turku Institute for Child and Youth Research. Conditions of being overweight and obese in childhood are common health problems with longlasting effects into adulthood. Currently 22% of Finnish boys and 12% of Finnish girls are overweight and 4% of Finnish boys and 2% of Finnish girls are obese. The foundation for later health is formed early, even before birth, and the importance of prenatal growth on later health outcomes is widely acknowledged. When the mother is overweight, had high gestational weight gain and disturbances in glucose metabolism during pregnancy, an increased risk of obesity in children is present. On the other hand, breastfeeding and later introduction of complementary foods are associated with a decreased obesity risk. In addition to these, many genetic and environmental factors have an effect on obesity risk, but the clustering of these factors is not extensively studied. The main objective of this thesis was to provide comprehensive information on prenatal and early postnatal factors associated with weight gain and obesity in infancy up to two years of age. The study was part of the STEPS Study (Steps to Healthy Development), which is a follow-up study consisting of 1797 families. This thesis focused on children up to 24 months of age. Altogether 26% of boys and 17% of girls were overweight and 5% of boys and 4% of girls were obese at 24 months of age according to New Finnish Growth references for Children BMI-for-age criteria. Compared to children who remained normal weight, the children who became overweight or obese showed different growth trajectories already at 13 months of age. The mother being overweight had an impact on children’s birth weight and early growth from birth to 24 months of age. The mean duration of breastfeeding was almost 2 months shorter in overweight women in comparison to normal weight women. A longer duration of breastfeeding was protective against excessive weight gain, high BMI, high body weight and high weight-for-length SDS during the first 24 months of life. Breast milk fatty acid composition differed between overweight and normal weight mothers, and overweight women had more saturated fatty acids and less n-3 fatty acids in breast milk. Overweight women also introduced complementary foods to their infants earlier than normal weight mothers. Genetic risk score calculated from 83 obesogenic- and adiposity-related single nucleotide polymorphisms (SNPs) showed that infants with a high genetic risk for being overweight and obese were heavier at 13 months and 24 months of age than infants with a low genetic risk, thus possibly predisposing to later obesity in obesogenic environment. Obesity Risk Score showed that children with highest number of risk factors had almost 6-fold risk of being overweight and obese at 24 months compared to children with lowest number of risk factors. The accuracy of the Obesity Risk Score in predicting overweight and obesity at 24 months was 82%. This study showed that many of the obesogenic risk factors tend to cluster within children and families and that children who later became overweight or obese show different growth trajectories already at a young age. These results highlight the importance of early detection of children with higher obesity risk as well as the importance of prevention measures focused on parents. Keywords: Breastfeeding, Child, Complementary Feeding, Genes, Glucose metabolism, Growth, Infant Nutrition Physiology, Nutrition, Obesity, Overweight, Programming
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Fiber-reinforced composite fixed dental prostheses – Studies of the materials used as pontics University of Turku, Faculty of Medicine, Institute of Dentistry, Department of Biomaterials Science, Finnish Doctoral Program in Oral Sciences – FINDOS, Annales Universitatis Turkuensis, Turku, Finland 2015 Fiber-reinforced composites (FRC), a non-metallic biomaterial, represent a suitable alternative in prosthetic dentistry when used as a component of fixed dental prostheses (FDPs). Some drawbacks have been identified in the clinical performance of FRC restorations, such as delamination of the veneering material and fracture of the pontic. Therefore, the current series of studies were performed to investigate the possibilities of enhancing the mechanical and physical properties of FRC FDPs by improving the materials used as pontics, to then heighten their longevity. Four experiments showed the importance of the pontic design and surface treatment in the performance of FRC FDPs. In the first, the load-bearing capacities of inlay-retained FRC FDPs with pontics of various materials and thicknesses were evaluated. Three different pontic materials were assessed with different FRC framework vertical positioning. Thicker pontics showed increased load-bearing capacities, especially ceramic pontics. A second study was completed investigating the influence of the chemical conditioning of the ridge-lap surface of acrylic resin denture teeth on their bonding to a composite resin. Increased shear bond strength demonstrated the positive influence of the pretreatment of the acrylic surfaces, indicating dissolution of the denture surfaces, and suggesting potential penetration of the monomer systems into the surface of denture teeth. A third study analyzed the penetration depth of different monomer systems on the acrylic resin denture teeth surfaces. The possibility of establishing a durable bond between acrylic pontics and FRC frameworks was demonstrated by the ability of monomers to penetrate the surface of acrylic resin denture teeth, measured by a confocal scanning type microscope. A fourth study was designed to evaluate the load-bearing capacities of FRC FDPs using the findings of the previous three studies. In this case, the performance of pre-shaped acrylic resin denture teeth used as pontics with different composite resins as filling materials was evaluated. The filling material influenced the load-bearing capacities, providing more durable FRC FDPs. It can be concluded that the mechanical and physical properties of FRC FDPs can be improved as has been shown in the development of this thesis. The improvements reported then might provide long lasting prosthetic solutions of this kind, positioning them as potentially permanent rehabilitation treatments. Key words: fiber-reinforced composite, fixed dental prostheses, inlay-retained bridges, adhesion, acrylic resin denture teeth, dental material.