970 resultados para Hill, Horatio.
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Case study on Oldham College and Edge Hill University working in partnership on a project to use screencasts as a way of providing feedback to learners.
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在我国生物力学是门新兴学科,它既是医学和生物医学工程发展的需要,也是力学学科发展的必然生物力学以医学、生理学、生物学的学要为出发点和归宿,把力学的和生物学的方法有机地结合起来,去解决这些学科工程中所需解决的问题
本书详细介绍了这方面的有关知识和研究成果
附录与关键词: 生物力学 概论 生物力学
目录
第一节 历史的源流第一章 生物力学概说
目录
第二节 背景和需要
第三节 全景鸟瞰
第二章 生物力学的力学基础
第一节 运动和力
2、1、1质点系动力学和刚体动力学基础
2、1、2刚体动力学在生物力学中的应用
2、1、3量纲和单位
2、2、1连续性假说
第二节 连续介质力学基本知识
2、2、2描述连续介质运动的两种方法
2、2、3应力
2、2、4应变·应变率
2、2、5变形功和应变能
2、2、6弹性和粘弹性
2、3、1流变学的方法学的一般原理
第三节 本构关系——流变学的主题
2、3、2Hooke(胡克)弹性体
2、3、3牛顿流体和非牛顿流体
2、3、4线性粘弹性体
2、4、1生命现象和流体运动
第四节 生物流体力学基础
2、4、2不同层次和不同系统中的生理流动问题
2、4、3流体力学的基本原理
2、4、4流体力学的基本方程
2、4、5量纲分析·相似参数
2、4、6生物流体力学的相似性问题
第五节 生物传质及其热力学基础
2、5、1热力学的基础定律
2、5、2扩散
2、5、3渗透·滤过
2、5、4组织间质中的渗流
2、5、5通过细胞膜的物质输运
结语:符号和语法
第三章 活组织的力学性质
第一节 骨的力学性质
3、2、1软组织的结构要素
第二节 软组织的力学性质
3、2、2软组织力学性质的实验方法
3、2、3软组织力学行为的一般特点
3、2、4软组织的本构方程
3、3、1血管壁的构造
第三节 血管的力学性质
3、3、2动脉血管的力学性质
3、3、3静脉血管的力学性质
3、3、4微血管的力学性质
第四节 关节 软骨的力学性质
3、4、1准线性粘弹性本构关系
3、4、2关节软骨的两相模型
3、5、1流体的粘弹性
第五节 生物粘弹性流体
3、5、2关节滑液的粘弹性
结语:生物流变学的理论和实践意义
第四章 肌肉力学基础
第一节 骨胳肌、心肌和平滑肌
第二节 骨胳肌的微结构和收缩机理
第三节 Hill方程和Hill模型
4、3、1Hill模型(双元素)
4、3、2三元素模型
4、4、1静息状态下心肌的力学性质
第四节 心肌的力学性质
4、4、2Hill模型应用于心肌
第五节 平滑肌的力学性质
结语:需要新概念、新技术
第五章 血液流变学导论
第一节 血液的流变特性
5、1、1宏观血液流变学的方法学原理
5、1、2血浆的粘度
5、1、3血液的粘性
5、1、4血液的粘弹性
第二节 血液非牛顿特性的细观和微观说明
第三节 红细胞的运动和变形
5、3、1红细胞的几何形状
5、3、2红细胞沉降——血沉
5、3、3红细胞的可变形性
5、3、4红细胞膜的力学性质
5、3、5红细胞聚集
5、4、1Fahreus—Lindqvist效应和Fahraeus效应
第四节 血液在微血管里的流变特性
5、4、2毛细血管内红细胞的运动和阻力
5、4、3毛细血管和毛细血管网络内红细胞的分布(比积的变化)
5、4、4表观粘度和相对粘度
5、5、1白细胞的力学性质
第五节 白细胞的流变行为
5、5、2白细胞在微血管里的流变行为
5、6、1血小板的活性与流变学因素
第六节 血小板功能行为的流变学问题
5、6、2凝血过程中血液的粘弹性
第七节 血液的本构方程
5、7、1几类粘弹性本构方程的述评
5、7、2可能的选择
结语:愿望和现实
第六章 心脏力学
第一节 心脏的构造和功能
第二节 心脏和心瓣的液体力学问题
6、2、1心脏和心瓣流体力学的若干基本问题
6、2、2二尖瓣的运动及其流场
6、2、3主动脉瓣的运动及其流场
6、3、1左心室的压力—容积关系
第三节 心脏的力学模型和泵功能
6、3、2左心室的应力和应变
6、3、3心脏的泵功能
6、4、1左心与动脉系统的相互作用
第四节 心脏与血管系统的相互作用
6、4、2左心系统和右心系统之间的相互作用
第五节 人造心脏瓣膜的生物力学问题
6、5、1人工心瓣的流体力学性能的检测和评价
6、5、2人工心瓣的疲劳寿命问题
结语:生物力学在生物医学工程中的位置
第七章 血液循环的力学规律
7、1、1分枝血管系统的阻力分布
第一节 动脉系统的阻力分布和分枝形态-Poiseuille定律的应用
7、1、2血管分枝形态的优化分析
7、2、1弹性直圆柱管里的定常层流
第二节 可变形管道内的定常流动
7、2、2血管的应力状态和弹性不稳定性
7、2、3可瘪管流动
7、2、4可变形管道内小扰动的传播
7、2、5三种流动的比较
7、2、6可变形管定常流动的稳定性问题
第三节 动脉血管里的脉动流和脉搏波
7、3、1脉搏波
7、3、2直圆柱管内的振荡流
第四节 脉搏波在动脉血管系统里的传播
7、4、1传输线理论——线性模型
7、4、2非线性数值模型
7、4、3中医脉象与脉搏波
7、5、1大动脉中流动的一般特点
第五节 大动脉里的流动
7、5、2动脉粥样硬化与血液流动的动力特性
7、5、3弯曲对大血管流动的影响
7、5、4分枝管道的流动
7、5、5动脉狭窄的流体力学问题
7、5、6血管分枝、弯曲、截面积突变部位红细胞和血小板的运动
第六节 静脉血管里的流动
7、6、1静脉血管的力学性质
7、6、2静脉中的脉动流和波动
7、6、3瓣膜对静脉血流的影响
第七节 微循环力学
7、7、1微循环的几种构造模式
7、7、2微循环力学参数的在体观测
7、7、3微循环力学问题概述
7、7、4毛细血流与周围组织之间的物质输运
第八节 肺血流的力学规律
7、8、1肺血管系统的几何形态
7、8、2肺血管力学性质
7、8、3肺毛细血管组织内的流动——片流模型
7、8、4肺毛细血管组织中血液的表观粘度
7、8、5肺血流的阻力
7、8、6理论的实验检验
结语:一个必然的趋势
第八章 呼吸力学
第一节 呼吸道内的空气流动
8、1、1呼吸道的阻力
8、1、2上呼吸道里的流动
8、1、3呼吸系统的动力学行为
第二节 支气管里的对流扩散
第三节 肺泡内气体的扩散
第四节 肺泡和毛细血流之间的气体交换
8、4、1通过膜的气体扩散
8、4、2肺泡—红细胞之间的气体交换
8、4、3扩散容量的实验测定
8、4、4肺通气量与血流量的关系
第五节 肺功能的宏观评价
第六节 肺呼气流量极限
第九章 器官力学的几个不同方面
第一节 耳蜗力学
9、1、1耳蜗的解剖特点和超微结构
9、1、2耳蜗管内的波传播
9、1、3小振幅下的非线性响应
第二节 脊柱力学
9、2、1脊柱的力学性质
9、2、2腰椎的受力分析
9、2、3脊柱的冲击损伤
9、3、1冲击和弹性波
第三节 肺的冲击损伤
9、3、2冲击载荷引起的肺水肿
9、3、3关于冲击损伤引起肺水肿的机理
结语:方法·概念·诀窃
第十章 应力和生长
第一节 从零应力状态到应力——生长假说
10、2、1心脏肥大
10、2、2肺的重建
第二节 软组织和器官的重建
10、2、3血管的重建
第三节 结构—功能适应性原理在骨生物力学中的体现
10、3、1骨折的愈合
10、3、2骨组织的重建
10、4、1血液流动对血管内皮细胞的影响
第四节 流体动力对细胞生长的影响
10、4、2流体动力对离体培养的血管内皮细胞生长的影响
结语:未来的新天地
Spatial mapping of sedimentary contaminants in the Baltimore Harbor/Patapsco river/Back river system
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Primary objective was to map concentrations of target contaminants in the surfacial sediments. Secondary objectives included: characterization of potential sites for sediment capping demonstration projects, further characterization of sediment depositional and accumulation patterns, and estimation of historical contaminant inventories through sediment geochronology. (PDF contains 112 pages)
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This thesis covers four different problems in the understanding of vortex sheets, and these are presented in four chapters.
In Chapter 1, free streamline theory is used to determine the steady solutions of an array of identical, hollow or stagnant core vortices in an inviscid, incompressible fluid. Assuming the array is symmetric to rotation through π radians about an axis through any vortex centre, there are two solutions or no solutions depending on whether A^(1/2)/L is less than or greater than 0.38 where A is the area of the vortex and L is the separation distance. Stability analysis shows that the more deformed shape is unstable to infinitesimal symmetric disturbances which leave the centres of the vortices undisplaced.
Chapter 2 is concerned with the roll-up of vortex sheets in homogeneous fluid. The flow over conventional and ring wings is used to test the method of Fink and Soh (1974). Despite modifications which improve the accuracy of the method, unphysical results occur. A possible explanation for this is that small scales are important and an alternate method based on "Cloud-in-Cell" techniques is introduced. The results show small scale growth and amalgamation into larger structures.
The motion of a buoyant pair of line vortices of opposite circulation is considered in Chapter 3. The density difference between the fluid carried by the vortices and the fluid outside is considered small, so that the Boussinesq approximation may be used. A macroscopic model is developed which shows the formation of a detrainment filament and this is included as a modification to the model. The results agree well with the numerical solution as developed by Hill (1975b) and show that after an initial slowdown, the vortices begin to accelerate downwards.
Chapter 4 reproduces completely a paper that has already been published (Baker, Barker, Bofah and Saffman (1974)) on the effect of "vortex wandering" on the measurement of velocity profiles of the trailing vortices behind a wing.
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The development of the vulva of the nematode Caenorhabditis elegans is induced by a signal from the anchor cell of the somatic gonad. Activity of the gene lin-3 is required for the Vulval Precursor Cells (VPCs) to assume vulval fates. It is shown here that lin-3 encodes the vulval-inducing signal.
lin-3 was molecularly cloned by transposon-tagging and shown to encode a nematode member ofthe Epidermal Growth Factor (EGF) family. Genetic epistasis experiments indicate that lin-3 acts upstream of let-23, which encodes a homologue of the EGF-Receptor.
lin-3 transgenes that contain multiple copies of wild-type lin-3 genomic DNA clones confer a dominant multivulva phenotype in which up to all six of the VPCs assume vulval fates. The properties of these trans genes suggest that lin-3 can act in the anchor cell to induce vulval fates. Ablation of the gonadal precursors, which prevents the development of the AC, strongly reduces the ability of lin-3 transgenes to stimulate vulval development. A lin-3 recorder transgene that retains the ability to stimulate vulval development is expressed specifically in the anchor cell at the time of vulval induction.
Expression of an obligate secreted form of the EGF domain of Lin-S from a heterologous promoter is sufficient to induce vulval fates in the absence of the normal source of the inductive signal. This result suggests that Lin-S may act as a secreted factor, and that Lin-S may be the sole vulval-inducing signal made by the anchor cell.
lin-3 transgenes can cause adjacent VPCs to assume the 1° vulval fate and thus can override the action of the lateral signal mediated by lin-12 that normally prevents adjacent 1° fates. This indicates that the production of Lin-3 by the anchor cell must be limited to allow the VPCs to assume the proper pattern of fates of so 3° 3° 2° 1° 2° 3°.
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The field of cavity-optomechanics explores the interaction of light with sound in an ever increasing array of devices. This interaction allows the mechanical system to be both sensed and controlled by the optical system, opening up a wide variety of experiments including the cooling of the mechanical resonator to its quantum mechanical ground state and the squeezing of the optical field upon interaction with the mechanical resonator, to name two.
In this work we explore two very different systems with different types of optomechanical coupling. The first system consists of two microdisk optical resonators stacked on top of each other and separated by a very small slot. The interaction of the disks causes their optical resonance frequencies to be extremely sensitive to the gap between the disks. By careful control of the gap between the disks, the optomechanical coupling can be made to be quadratic to first order which is uncommon in optomechanical systems. With this quadratic coupling the light field is now sensitive to the energy of the mechanical resonator and can directly control the potential energy trapping the mechanical motion. This ability to directly control the spring constant without modifying the energy of the mechanical system, unlike in linear optomechanical coupling, is explored.
Next, the bulk of this thesis deals with a high mechanical frequency optomechanical crystal which is used to coherently convert photons between different frequencies. This is accomplished via the engineered linear optomechanical coupling in these devices. Both classical and quantum systems utilize the interaction of light and matter across a wide range of energies. These systems are often not naturally compatible with one another and require a means of converting photons of dissimilar wavelengths to combine and exploit their different strengths. Here we theoretically propose and experimentally demonstrate coherent wavelength conversion of optical photons using photon-phonon translation in a cavity-optomechanical system. For an engineered silicon optomechanical crystal nanocavity supporting a 4 GHz localized phonon mode, optical signals in a 1.5 MHz bandwidth are coherently converted over a 11.2 THz frequency span between one cavity mode at wavelength 1460 nm and a second cavity mode at 1545 nm with a 93% internal (2% external) peak efficiency. The thermal and quantum limiting noise involved in the conversion process is also analyzed and, in terms of an equivalent photon number signal level, are found to correspond to an internal noise level of only 6 and 4 times 10x^-3 quanta, respectively.
We begin by developing the requisite theoretical background to describe the system. A significant amount of time is then spent describing the fabrication of these silicon nanobeams, with an emphasis on understanding the specifics and motivation. The experimental demonstration of wavelength conversion is then described and analyzed. It is determined that the method of getting photons into the cavity and collected from the cavity is a fundamental limiting factor in the overall efficiency. Finally, a new coupling scheme is designed, fabricated, and tested that provides a means of coupling greater than 90% of photons into and out of the cavity, addressing one of the largest obstacles with the initial wavelength conversion experiment.
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The two-pulse stimulated radiation of dense (10^9/cm^3 < ne ≤ 10^(11) /cm^3) nonuniform neon and argon afterglow plasma columns longitudinally immersed in a magnetic field is studied. The magnetic field is very homogeneous over the plasma volume (∆B/B~.01%). If the S-band microwave pulses' center frequency is such that they resonantly excite a narrow band of plasma upper hybrid oscillations close to the maximum upper hybrid frequency of the column, strong two pulse echoes are observed. This new echo process is called the upper hybrid echo. The echo spectrum, echo power and echo width were studied as a function of the pulse peak power P, pulse separation τ, relative density (ω_(po)/ω)^2, and relative cyclotron frequency (ω_c/ω). The complex but systematic variations of the echo properties as a function of the above-mentioned parameters arc found to be in qualitative agreement with those predicted by a theory of Gould and Blum based upon a simple nonuniform unidimensional cold plasma slab model. The possible effects of electron neutral and electron ion collisions not retained in the theoretical model are discussed.
The existence of a new type of cyclotron echo, different from that of Hill and Kaplan and not predicted by the Blum and Gould model is documented. It is believed to be also of a collective effect nature and can probably be described in terms of a theory retaining some hot plasma effects.
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The purpose of this investigation was to determine whether landslides could be predicted for hill slopes of known inclinations from data secured by laboratory tests performed on samples of the ground under consideration. Specifically, the investigation was to show whether a correlation existed between experimentally determined values for friction and cohesion of ground and calculated values based upon the configuration of earth masses that had slid. The ability to determine the stability of slopes from experimental data is of obvious significance.
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The Pacoima area is located on an isolated hill in the northeast section of the San Fernando, the northeast portion of the Pacoima Quadrangle, Los Angeles County, California. Within it are exposed more than 2300 feet of Tertiary rocks, which comprise three units of Middle Miocene (?) age, and approximately 950 feet of Jurassic (?) granite basement. The formations are characterized by their mode of occurrence, marine and terrestial origin, diverse lithology, and structural features.
The basement complex is composed of intrusive granite, small masses of granodiorite and a granodiorite gneiss with the development of schistosity in sections. During the long period of erosion of the metamorphics, the granitic rocks were exposed and may have provided clastic constituents for the overlying formations.
As a result of rapid sedimentation in a transitional environment, the Middle Miocene Twin Peaks formation was laid down unconformably on the granite. This formation is essentially a large thinning bed of gray to buff pebble and cobble conglomerate grading to coarse yellow sandstone. The contact of conglomerate and granite is characterized by its faulted and depositional nature.
Beds of extrusive andesite, basalt porphyry, compact vesicular amygdaloidal basalts, andesite breccia, interbedded feldspathic sands and clays of terrestial origin, and mudflow breccia comprise the Pacoima formation which overlies the Twin Peaks formation unconformably. A transgressing shallow sea accompanied settling of the region and initiated deposition of fine clastic sediments.
The marine Topanga (?) formation is composed of brown to gray coarse sandstone grading into interbedded buff sandstones and gray shales. Intrusions of rhyolitedacite and ash beds mark continued but sporatic volcanism during this period.
The area mapped represents an arch in the Tertiary sediments. Forces that produced the uplift of the granite structural high created stresses that were relieved by jointing and faulting. Vertical and horizontal movement along these faults has displaced beds, offset contacts and complicated their structure. Uplift and erosion have exposed the present sequence of beds which dip gently to the northeast. The isolated hill is believed to be in an early stage of maturity.
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The behavior of spheres in non-steady translational flow has been studied experimentally for values of Reynolds number from 0.2 to 3000. The aim of the work was to improve our qualitative understanding of particle transport in turbulent gaseous media, a process of extreme importance in power plants and energy transfer mechanisms.
Particles, subjected to sinusoidal oscillations parallel to the direction of steady translation, were found to have changes in average drag coefficient depending upon their translational Reynolds number, the density ratio, and the dimensionless frequency and amplitude of the oscillations. When the Reynolds number based on sphere diameter was less than 200, the oscillation had negligible effect on the average particle drag.
For Reynolds numbers exceeding 300, the coefficient of the mean drag was increased significantly in a particular frequency range. For example, at a Reynolds number of 3000, a 25 per cent increase in drag coefficient can be produced with an amplitude of oscillation of only 2 per cent of the sphere diameter, providing the frequency is near the frequency at which vortices would be shed in a steady flow at the mean speed. Flow visualization shows that over a wide range of frequencies, the vortex shedding frequency locks in to the oscillation frequency. Maximum effect at the natural frequency and lock-in show that a non-linear interaction between wake vortex shedding and the oscillation is responsible for the increase in drag.
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Tendo como incipt Junto dum seco, fero e estéril monte, a Canção V de Luís de Camões, presente no corpus mínimo proposto pelo Professor Leodegário de Azevedo Filho é tema deste estudo que se propõe a fazer uma análise literária à luz do Maneirismo, onde se buscam observar as principais características temáticas presentes na mesma. Dessa forma, temas como o desconcerto do mundo, a fugacidade do tempo e da vida e, consequentemente, o pessimismo e a ausência da amada serão relacionados à poesia. Há a preocupação de se atentar para a influência tardo-gótica no Maneirismo e como isso se dá nessa canção, o que faz com que se perceba não haver traços clássicos ou renascentistas na mesma. Faz-se necessário ainda que se analisem as referências geográficas, as construções e os recursos estilísticos utilizados pelo poeta, uma vez que estes são significativos para uma boa compreensão da canção, bem como para um possível questionamento acerca da obra de Camões ser considerada por alguns autores clássica
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There is no evidence of an increase in the acidity (lower pH or alkalinity) of water-bodies in the Lake District over the last 50 years. Brown trout occur in acid streams and upland tarns where pH is 4.5-5.2 throughout the year. Their occurrence in such waters in Britain and Ireland has been known for most of this century and there is no previous evidence of harmful effects on salmonid fisheries, though numbers of fish are naturally low. However, many benthic invertebrates that are common in hill-streams where pH is above 5.7 do not occur in more acid streams. This phenomenon occurs in the headwaters of several western rivers in Cumbria. It is not a recent response to "acid rain". Harmful effects of pH are undoubtedly more pronounced in waters that are poor in other dissolved ions. Low concentrations of sodium, potassium, calcium and chloride are especially important and may limit the distributions of some aquatic animals even where pH is above 5.7. The concentration of sulphate ions is usually relatively high but this is not important to the fauna; concentrations are at least two times higher in productive alkaline water-bodies than they are in unproductive acid waters.
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The wave-theoretical analysis of acoustic and elastic waves refracted by a spherical boundary across which both velocity and density increase abruptly and thence either increase or decrease continuously with depth is formulated in terms of the general problem of waves generated at a steady point source and scattered by a radially heterogeneous spherical body. A displacement potential representation is used for the elastic problem that results in high frequency decoupling of P-SV motion in a spherically symmetric, radially heterogeneous medium. Through the application of an earth-flattening transformation on the radial solution and the Watson transform on the sum over eigenfunctions, the solution to the spherical problem for high frequencies is expressed as a Weyl integral for the corresponding half-space problem in which the effect of boundary curvature maps into an effective positive velocity gradient. The results of both analytical and numerical evaluation of this integral can be summarized as follows for body waves in the crust and upper mantle:
1) In the special case of a critical velocity gradient (a gradient equal and opposite to the effective curvature gradient), the critically refracted wave reduces to the classical head wave for flat, homogeneous layers.
2) For gradients more negative than critical, the amplitude of the critically refracted wave decays more rapidly with distance than the classical head wave.
3) For positive, null, and gradients less negative than critical, the amplitude of the critically refracted wave decays less rapidly with distance than the classical head wave, and at sufficiently large distances, the refracted wave can be adequately described in terms of ray-theoretical diving waves. At intermediate distances from the critical point, the spectral amplitude of the refracted wave is scalloped due to multiple diving wave interference.
These theoretical results applied to published amplitude data for P-waves refracted by the major crustal and upper mantle horizons (the Pg, P*, and Pn travel-time branches) suggest that the 'granitic' upper crust, the 'basaltic' lower crust, and the mantle lid all have negative or near-critical velocity gradients in the tectonically active western United States. On the other hand, the corresponding horizons in the stable eastern United States appear to have null or slightly positive velocity gradients. The distribution of negative and positive velocity gradients correlates closely with high heat flow in tectonic regions and normal heat flow in stable regions. The velocity gradients inferred from the amplitude data are generally consistent with those inferred from ultrasonic measurements of the effects of temperature and pressure on crustal and mantle rocks and probable geothermal gradients. A notable exception is the strong positive velocity gradient in the mantle lid beneath the eastern United States (2 x 10-3 sec-1), which appears to require a compositional gradient to counter the effect of even a small geothermal gradient.
New seismic-refraction data were recorded along a 800 km profile extending due south from the Canadian border across the Columbia Plateau into eastern Oregon. The source for the seismic waves was a series of 20 high-energy chemical explosions detonated by the Canadian government in Greenbush Lake, British Columbia. The first arrivals recorded along this profile are on the Pn travel-time branch. In northern Washington and central Oregon their travel time is described by T = Δ/8.0 + 7.7 sec, but in the Columbia Plateau the Pn arrivals are as much as 0.9 sec early with respect to this line. An interpretation of these Pn arrivals together with later crustal arrivals suggest that the crust under the Columbia Plateau is thinner by about 10 km and has a higher average P-wave velocity than the 35-km-thick, 62-km/sec crust under the granitic-metamorphic terrain of northern Washington. A tentative interpretation of later arrivals recorded beyond 500 km from the shots suggests that a thin 8.4-km/sec horizon may be present in the upper mantle beneath the Columbia Plateau and that this horizon may form the lid to a pronounced low-velocity zone extending to a depth of about 140 km.