Implant Stability Measurements of Two Immediate Loading Protocols for the Edentulous Mandible: Rigid and Semi-rigid Splinting of the Implants

Aim: Primary and secondary stabilities of immediately loaded mandibular implants restored with fixed prostheses (FP) using rigid or semirigid splinting systems were clinically and radiographically evaluated. Methods: Fifteen edentulous patients were rehabilitated using hybrid FP; each had 5 implants placed between the mental foramens. Two groups were randomly divided: group 1-FP with the conventional rigid bar splinting the implants and group 2-semi-rigid cantilever extension system with titanium bars placed in the 2 distal abutment cylinders. Primary stability was evaluated using resonance frequency analysis after installation of the implant abutments. The measurements were made at 3 times: T0, at baseline; T1, 4 months after implant placement; and T2, 8 months after implant placement. Presence of mobility and inflammation in the implant surrounding regions were checked. Stability data were submitted to statistical analysis for comparison between groups (P, 0.05). Results: Implant survival rate for the implants was of 100% in both groups. No significant differences in the mean implant stability quotient values were found for both groups from baseline and after the 8-month follow-up. Conclusion: The immediate loading of the implants was satisfactory, and both splinting conditions (rigid and semi-rigid) can be successfully used for the restoration of edentulous mandibles. (Implant Dent 2012;21:486-490)

Metabolic engineering of beta-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis

Industrial production of semi-synthetic cephalosporins by Penicillium chrysogenum requires supplementation of the growth media with the side-chain precursor adipic acid. In glucose-limited chemostat cultures of P. chrysogenum, up to 88% of the consumed adipic acid was not recovered in cephalosporinrelated products, but used as an additional carbon and energy source for growth. This low efficiency of side-chain precursor incorporation provides an economic incentive for studying and engineering the metabolism of adipic acid in P. cluysogenum. Chemostat-based transcriptome analysis in the presence and absence of adipic acid confirmed that adipic acid metabolism in this fungus occurs via beta-oxidation. A set of 52 adipate-responsive genes included six putative genes for acyl-CoA oxidases and dehydrogenases, enzymes responsible for the first step of beta-oxidation. Subcellular localization of the differentially expressed acyl-CoA oxidases and dehydrogenases revealed that the oxidases were exclusively targeted to peroxisomes, while the dehydrogenases were found either in peroxisomes or in mitochondria. Deletion of the genes encoding the peroxisomal acyl-CoA oxidase Pc20g01800 and the mitochondrial acyl-CoA dehydrogenase Pc20g07920 resulted in a 1.6- and 3.7-fold increase in the production of the semi-synthetic cephalosporin intermediate adipoyl-6-APA, respectively. The deletion strains also showed reduced adipate consumption compared to the reference strain, indicating that engineering of the first step of beta-oxidation successfully redirected a larger fraction of adipic acid towards cephalosporin biosynthesis. (C) 2012 Elsevier Inc. All rights reserved.

Consumo e custo de recursos materiais em unidades pediátricas de terapia intensiva e semi-intensiva

O gerenciamento de custos de materiais de consumo hospitalar é um tema atual em pesquisa, principalmente em unidades de saúde especializadas. Os enfermeiros são destacados como os principais gestores do consumo e custo de materiais hospitalares. Neste estudo, objetivou-se caracterizar unidades pediátricas semi-intensivas e intensivas de um hospital de ensino e verificar o consumo e os custos de materiais utilizados na assistência a pacientes internados nessas unidades. Estudo descritivo, exploratório, retrospectivo, com abordagem quantitativa; os dados foram obtidos do Sistema de Informação Hospitalar; analisados com base na classificação ABC. O gasto médio foi semelhante entre as UTIs cardiológica e neonatal e menor nas UTI e semi-intensiva pediátricas; houve variação significativa de consumo mensal de materiais; os materiais de maior custo tiveram mais impacto no orçamento das unidades estudadas. Os dados obtidos revelaram a importância do uso de método sistêmico de análise de consumo e gastos de materiais em unidades pediátricas e subsidiam ações administrativas de economia.

Hydro-physical characterization of soils under tropical semi-deciduous forest

The study of the hydro-physical behavior in soils using toposequences is of great importance for better understanding the soil, water and vegetation relationships. This study aims to assess the hydro-physical and morphological characterization of soil from a toposequence in Galia, state of São Paulo, Brazil). The plot covers an area of 10.24 ha (320 × 320 m), located in a semi-deciduous seasonal forest. Based on ultra-detailed soil and topographic maps of the area, a representative transect from the soil in the plot was chosen. Five profiles were opened for the morphological description of the soil horizons, and hydro-physical and micromorphological analyses were performed to characterize the soil. Arenic Haplustult, Arenic Haplustalf and Aquertic Haplustalf were the soil types observed in the plot. The superficial horizons had lower density and greater hydraulic conductivity, porosity and water retention in lower tensions than the deeper horizons. In the sub-superficial horizons, greater water retention at higher tensions and lower hydraulic conductivity were observed, due to structure type and greater clay content. The differences observed in the water retention curves between the sandy E and the clay B horizons were mainly due to the size distribution, shape and type of soil pores.

Complexity of inferences in polytree-shaped semi-qualitative probabilistic networks

Semi-qualitative probabilistic networks (SQPNs) merge two important graphical model formalisms: Bayesian networks and qualitative probabilistic networks. They provade a very Complexity of inferences in polytree-shaped semi-qualitative probabilistic networks and qualitative probabilistic networks. They provide a very general modeling framework by allowing the combination of numeric and qualitative assessments over a discrete domain, and can be compactly encoded by exploiting the same factorization of joint probability distributions that are behind the bayesian networks. This paper explores the computational complexity of semi-qualitative probabilistic networks, and takes the polytree-shaped networks as its main target. We show that the inference problem is coNP-Complete for binary polytrees with multiple observed nodes. We also show that interferences can be performed in time linear in the number of nodes if there is a single observed node. Because our proof is construtive, we obtain an efficient linear time algorithm for SQPNs under such assumptions. To the best of our knowledge, this is the first exact polynominal-time algorithm for SQPn. Together these results provide a clear picture of the inferential complexity in polytree-shaped SQPNs.

Overview of semi-sinusoidal stellar variability with the CoRoT satellite

Context. To date, the CoRoT space mission has produced more than 124 471 light curves. Classifying these curves in terms of unambiguous variab ility behavior is mandatory for obtaining an unbi ased statistical view on th eir controlling root-causes. Aims. The present study provides an overview of semi-sinusoidal light curves observed by the CoRoT exo-field CCDs. Methods. We selected a sample of 4206 light curves presenting well-defined semi-si nusoidal signatures. Th e variability periods were computed based on Lomb-Scargle periodograms, harmonic fits, and visual inspection. Results. Color–period diagrams for the present sample show the trend of an increase of the variability periods as long as the stars evolve. This evolutionary behavior is also noticed when comparing the period distribution in the Galactic center and anti-center directions. These aspect s indicate a compatibility with stellar rotation, although more inform ation is needed to confirm their root- causes. Considering this possi bility, we identified a subset of th ree Sun-like candidates by their photometric peri od. Finally, the variability period versus color diagr am behavior was found to be highly depe ndent on the reddening correction.

Diagnósticos de enfermagem em cuidadores de crianças com fissuras orofaciais e anomalias relacionadas internadas em unidade semi-intensiva

Objetivo: Identificar os diagnósticos de enfermagem em cuidadores de crianças com fissura orofaciais e anomalias relacionadas, internadas em unidade de cuidado semi-intensivo. Método: Estudo prospectivo, realizado na unidade de terapia semi-intensiva do Hospital de Reabilitação de Anomalias Craniofaciais da Universidade de São Paulo, nos meses de maio e junho de 2013. A amostra constou de 20 cuidadores. O critério de inclusão foi à adesão. Por meio da entrevista estruturada, os participantes foram avaliados em dois momentos distintos: na internação da criança e na alta hospitalar. Os diagnósticos foram formalizados segundo a taxonomia da NANDAInternacional, com enfoque psicossocial. Resultados: A amostra foi composta exclusivamente por mães, com idade média de 28,35 anos, ensino médio completo (60%), classe social média (60%), com união estável (75%) e moradia própria (75%). No momento da internação prevaleceram: o domínio papéis e relacionamentos (22%); a classe papéis do cuidador (85%), e os DE: tensão do papel de cuidador (100%), ansiedade (100%), disposição para o conhecimento aumentado (85%), disposição para controle aumentado do regime terapêutico (80%) e padrão de sono prejudicado (55%). No momento da alta prevaleceram: o domínio enfrentamento/tolerância ao estresse (33%); a classe respostas de enfrentamento (72%), e os DE: disposição para maternidade melhorada (50%), disposição para enfrentamento aumentada (50%), disposição para enfrentamento familiar aumentado (50%). Conclusão: Embora inicialmente os cuidadores tenham apresentado estresse, possivelmente devido à necessidade do aprendizado para a manutenção dos cuidados após a alta hospitalar, evidenciou-se posteriormente uma progressão em relação à aceitação situacional/enfrentamento.

A semi-supervised classification technique based on interacting forces

Semi-supervised learning is a classification paradigm in which just a few labeled instances are available for the training process. To overcome this small amount of initial label information, the information provided by the unlabeled instances is also considered. In this paper, we propose a nature-inspired semi-supervised learning technique based on attraction forces. Instances are represented as points in a k-dimensional space, and the movement of data points is modeled as a dynamical system. As the system runs, data items with the same label cooperate with each other, and data items with different labels compete among them to attract unlabeled points by applying a specific force function. In this way, all unlabeled data items can be classified when the system reaches its stable state. Stability analysis for the proposed dynamical system is performed and some heuristics are proposed for parameter setting. Simulation results show that the proposed technique achieves good classification results on artificial data sets and is comparable to well-known semi-supervised techniques using benchmark data sets.

Monte Carlo Semi-Empirical Model for Si(Li) X-Ray Detector: Differences between Nominal and Fitted Parameters.

A detailed characterization of a X-ray Si(Li) detector was performed to obtain the energy dependence of efficiency in the photon energy range of 6.4 - 59.5 keV. which was measured and reproduced by Monte Carlo (MC) simulations. Significant discrepancies between MC and experimental values were found when lhe manufacturer parameters of lhe detector were used in lhe simulation. A complete Computerized Tomagraphy (CT) detector scan allowed to find the correct crystal dimensions and position inside the capsule. The computed efficiencies with the resulting detector model differed with the measured values no more than 10% in most of the energy range.

Dry spell mitigation to upgrade semi-arid rainfed agriculture : Water harvesting and soil nutrient management for smallholder maize cultivation in Machakos, Kenya

Improvements in on-farm water and soil fertility management through water harvesting may prove key to up-grade smallholder farming systems in dry sub-humid and semi-arid sub-Sahara Africa (SSA). The currently experienced yield levels are usually less than 1 t ha-1, i.e., 3-5 times lower than potential levels obtained by commercial farmers and researchers for similar agro-hydrological conditions. The low yield levels are ascribed to the poor crop water availability due to variable rainfall, losses in on-farm water balance and inherently low soil nutrient levels. To meet an increased food demand with less use of water and land in the region, requires farming systems that provide more yields per water unit and/or land area in the future. This thesis presents the results of a project on water harvesting system aiming to upgrade currently practised water management for maize (Zea mays, L.) in semi-arid SSA. The objectives were to a) quantify dry spell occurrence and potential impact in currently practised small-holder grain production systems, b) test agro-hydrological viability and compare maize yields in an on-farm experiment using combinations supplemental irrigation (SI) and fertilizers for maize, and c) estimate long-term changes in water balance and grain yields of a system with SI compared to farmers currently practised in-situ water harvesting. Water balance changes and crop growth were simulated in a 20-year perspective with models MAIZE1&2. Dry spell analyses showed that potentially yield-limiting dry spells occur at least 75% of seasons for 2 locations in semi-arid East Africa during a 20-year period. Dry spell occurrence was more frequent for crop cultivated on soil with low water-holding capacity than on high water-holding capacity. The analysis indicated large on-farm water losses as deep percolation and run-off during seasons despite seasonal crop water deficits. An on-farm experiment was set up during 1998-2001 in Machakos district, semi-arid Kenya. Surface run-off was collected and stored in a 300m3 earth dam. Gravity-fed supplemental irrigation was carried out to a maize field downstream of the dam. Combinations of no irrigation (NI), SI and 3 levels of N fertilizers (0, 30, 80 kg N ha-1) were applied. Over 5 seasons with rainfall ranging from 200 to 550 mm, the crop with SI and low nitrogen fertilizer gave 40% higher yields (**) than the farmers’ conventional in-situ water harvesting system. Adding only SI or only low nitrogen did not result in significantly different yields. Accounting for actual ability of a storage system and SI to mitigate dry spells, it was estimated that a farmer would make economic returns (after deduction of household consumption) between year 2-7 after investment in dam construction depending on dam sealant and labour cost used. Simulating maize growth and site water balance in a system of maize with SI increased annual grain yield with 35 % as a result of timely applications of SI. Field water balance changes in actual evapotranspiration (ETa) and deep percolation were insignificant with SI, although the absolute amount of ETa increased with 30 mm y-1 for crop with SI compared to NI. The dam water balance showed 30% productive outtake as SI of harvested water. Large losses due to seepage and spill-flow occurred from the dam. Water productivity (WP, of ETa) for maize with SI was on average 1 796 m3 per ton grain, and for maize without SI 2 254 m3 per ton grain, i.e, a decerase of WP with 25%. The water harvesting system for supplemental irrigation of maize was shown to be both biophysically and economically viable. However, adoption by farmers will depend on other factors, including investment capacity, know-how and legislative possibilities. Viability of increased water harvesting implementation in a catchment scale needs to be assessed so that other down-stream uses of water remains uncompromised.

Gran hidráulica y ocupación de la geografía árida de Norteamérica: una aproximación histórica, 1860-1960

[ES] Este trabajo tiene como propósito realizar una primera aproximación al proceso histórico de ocupación de la geografía árida de Norteamérica (1860-1960) que integra la frontera norte de México con el sureste de los Estados Unidos. Se hace énfasis en el impacto general que en este proceso jugó la revolución industrial y tecno-científica que la acompañó y específicamente el papel desempeñado de la Gran Hidráulica en la explotación de los recursos hídricos a gran escala, habilitando el desarrollo productivo y social. Como parte del cambio histórico se expone también la emergencia de un moderno marco jurídico-institucional en torno al agua. Se cierra con la exposición de dos casos regionales para mostrar las crecientes rivalidades por los recursos hídricos ante sus nuevos usos modernos y su explotación intensiva, así como las diferentes modalidades de gestión resultantes y sus impactos en el largo plazo. [EN] This work aims to make a first approach to the historical process of occupation of the arid geography of North America (1860-1960) that integrates the northern border of Mexico with the southeast of the United States. Emphasis on the general impact that this process played the industrial and technoscientific revolution that accompanied it and specifically the role of the great hydraulic in the exploitation of large-scale water resources, enabling productive and social development. As part of the historic change is also the emergence of a modern legal- institutional framework around water. It closes with the exhibition of two regional cases to show the growing rivalries for water resources to its new modern uses and its intensive exploitation, as well as the different forms of management resulting and their impacts in the long term.