Seqüência de moebius: Manifestações clínicas e avaliação auditiva

Introduction: Children with Moebius syndrome may present paralysis of cranial nerves III, IV, V, VI, VII, VIII, IX, X and XII, compromising motor and sensorial functions. Hands and feet defects (syndactyly, equinovarus and arthrogryposis) are frequently associated. These manifestations can be attributed to the use of misoprostol during pregnancy to induce abortion. Study design: Clinical prospective. Aim: To evaluate the main clinical manifestations, hearing acuity and possible etiologic factors in children with Moebius syndrome. Material and method: The children were submitted to clinical, otolaryngological and hearing acuity assessment. Hearing acuity was evaluated through behavioral tests, pure tone audiometry, tympanometry and auditory brainstem response (ABR). We investigated possible etiologic factors. Results: Three boys and two girls were evaluated. The main manifestations were: facial paralysis, paralysis of masseter muscle, defects in dental occlusion, retraction of tympanic membrane, equinovarus, oblique palpebral fissure and tongue atrophy. Conductive hearing loss was detected in three children and sensorineural hearing loss in one child. The use of misoprostol during pregnancy was reported by four mothers. Conclusions: The children with Moebius syndrome evaluated in the present study manifested palsies of various cranial nerves, especially V, VII and XII nerves, responsible for motor and sensorial alterations. Inadequate eustachian tube function associated to conductive hearing loss was frequent. The use of misoprostol during pregnancy was reported by the mothers and it was considered a possible etiologic factor.

Eucalyptus ESTs corresponding to the protoporphyrinogen IX oxidase enzyme related to the synthesis of heme, chlorophyll, and to the action of herbicides

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estudo anatômico e distribuição das papilas valadas no gato doméstico

The tongue of domestic animals varies in size and shape and according to these animals feeding habits, there are different degrees of tongue surface specialization. At the dorsal surface of the tongue lingual papillae can be observed, such as the vallate papillae, related to taste perception. With the help of a magnifying glass, differences in the number, size and distribution of vallate papillae were studied. Fifty five tongues of adult domestic cats from both sexes (38 females and 17 males) were analyzed. The samples were fixed in 10% buffered formalin. The vallate papillae were found to be symmetrically distributed on 21 tongues (38.18%). However, it was observed that in some of the tongues the number of vallate papillae varied when one side of the tongue was compared to its contralateral side. The vallate papillae showed different shapes: elongated (42.58%), oval (31.61%), round (25.48%) and pear shaped (0.33%). The vallate papillae were classified into 10 different categories: symmetrical I (2 right and 2 left), II (3:3), III (4:4) and asymmetrical IV (3:2), V (4:2), VI (2:3), VII (4:3), VIII (5:3), IX (3:4) and X (4:5). Measurements of length and width were made with averages of 0.84 ± 0.23 mm and 0.55 ± 0.18 mm, respectively, besides the calculation of the total area of these papillae per tongue, that showed average of 2,74 ± 0,31 mm 2 in males and 1,94 ± 0,14 mm 2 in females However, upon examining the lingual papillae of the cat tongues, specimens demonstrating 7, 8 or 9 vallate papillae, arranged in pairs (4:3, 5:3, 3:4 and 4:5) by category, were observed in this study but not cited in the literature.

Panorama de la Inserción Internacional de América Latina y el Caribe 1997

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Panorama de la Inserción Internacional de América Latina y el Caribe 1998

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Latin America and the Caribbean in the World Economy 1999-2000

Includes bibliography

Latin America and the Caribbean in the World Economy 1998

Includes bibliography

β-casein gene polymorphism permits identification of bovine milk mixed with bubaline milk in mozzarella cheese

Mozzarella cheese is traditionally prepared from bubaline (Bubalus bubalis) milk, but product adulteration occurs mainly by addition of or full substitution by bovine milk. The aim of this study was to show the usefulnes of molecular markers to identify the admixture of bovine milk to bubaline milk during the manufacturing process of mozzarella cheese. Samples of mozzarella cheese were produced by adding seven different concentrations of bovine milk: 0%, 1%, 2%, 5%, 8%, 12% and 100%. DNA extracted from somatic cells found in cheese were submitted to PCR-RFLP analysis of casein genes: α-s1-CN - CSN1S1 that encompasses 954 bp from exon VII to intron IX (AluI and HinfI), β-CN - CSN2 including 495 bp of exon VII (Hae III and HinfI), and κ-CN - CSN3, encompassing 373 bp of exon IV (AluI and HindIII). Our results indicate that Hae III-RFLP of CSN2exon VII can be used as a molecular marker to detect the presence of bovine milk in mozzarella cheese. Copyright © 2008, Sociedade Brasileira de Genética.

Empresas y empresarios en la historia de Colombia, siglos XIX-XX: una colección de estudios recientes

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Sustainable development: changing production patterns, social equity and the environment

Includes bibliography

Fostering economic policy coordination in Latin America: the REDIMA approach to escaping the prisoner's dilemma

Includes bibliography

Fomentar la coordinación de las políticas económicas en América Latina: el método REDIMA para salir del dilema del prisionero

Incluye Bibliografía

Pionero de la paz: Homenaje a Dag Hammarskjöld

En este libro se recogen los respetos brindados a este ilustre sueco en Santiago por destacadas personalidades de las relaciones internacionales, los derechos humanos y el derecho internacional. A través de ellos es posible hacerse una idea cabal de sus significativos aportes, su infatigable estilo de trabajo y la impronta que dejó como legado inspirador y desafío para las generaciones venideras.

Guía metodológica: diseño de indicadores compuestos de desarrollo sostenible

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Procedimientos de gestión para el desarrollo sustentable

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