O SIVICC como um sistema dissuasor da ilicitude e de apoio à atividade operacional da GNR

O objeto de estudo da presente investigação é o SIVICC. Sendo o objetivo geral demonstrar o seu desempenho organizacional nos domínios da dissuasão da ilicitude, do apoio à decisão e do suporte à atividade operacional da GNR, procurando adicionar e aprofundar conhecimento teórico e empírico. Em termos de metodologia optámos por uma estratégia de investigação qualitativa e relativamente ao desenho da pesquisa optou-se pela transversal. Os métodos e técnicas utilizadas foram as entrevistas semiestruturadas com a respetiva análise de conteúdo e a análise documental. Como resultado principal destacamos que, com base numa doutrina assente em princípios centrados em rede e no empirismo resultante das entrevistas efetuadas, o SIVICC proporciona superioridade de informação resultando numa consciência situacional partilhada da organização, o que conduz a melhores efeitos operacionais, que contribuem na prossecução da segurança de Portugal e da UE, através de uma efetiva vigilância diária e controlo do mar territorial e zona costeira. Concluímos que o SIVICC promove um apoio importante na tomada de decisão e suporta eficazmente e eficientemente a atividade operacional da GNR, que se vai refletir numa vantagem competitiva sobre o adversário que é persuadido a mudar os seus comportamentos através da dissuasão que o sistema proporciona. Abstract: The study object of this research is the SIVICC. The overall goal is to prove their organizational performance in the areas of deterrence of unlawful, in decision support and in supporting the operational activities of the GNR, attempting to add and deepen theoretical and empirical knowledge. In terms of methodology we chose a qualitative research strategy and for the design of research we chose the transversal. The methods and techniques used were semi-structured interviews with the respective content analysis and document analysis. The main result we highlight, based on a doctrine sustained on principles of centered network operations and a result empiricism of conducted interviews, that the SIVICC provides information superiority resulting in a shared situational awareness of the organization, leading to better operational effects that contribute to the pursuit security in Portugal and in the EU, through effective daily monitoring and control of the territorial sea and coastal zone. We conclude that the SIVICC promotes an important support decision making and supports effectively and efficiently operational activity of the GNR, which will reflect a competitive advantage over the adversary who is persuaded to change their behavior through deterrence that the system provides.

Qualidade do sono, atividade física e funcionamento físico de pessoas idosas independentes

O objetivo deste estudo foi analisar associações entre a qualidade do sono, a atividade física e o funcionamento físico (aptidão física e atividades da vida diária (AVD)) de pessoas idosas independentes. Metodologia: A amostra incluiu 437 pessoas idosas independentes (143 homens e 294 mulheres; 65-103 anos). A qualidade do sono e as AVD foram avaliadas através de questionário, a atividade física através de acelerometria e a aptidão física através do Senior Fitness Test. Resultados: A análise da regressão logística tendo como variável dependente a qualidade do sono e como variáveis independentes a atividade física, a aptidão física e as AVD, revelou que as AVD foi a única variável explicativa da discriminação entre má e boa qualidade do sono. O aumento de um ponto nas AVD correspondeu a uma diminuição de 91,4% na probabilidade de ter uma má qualidade de sono. Os resultados não foram alterados quando se incluiu no modelo o género, a idade ou o escalão etário. Conclusões: Um melhor funcionamento físico parece estar associado a uma melhor qualidade do sono em pessoas idosas. A obtenção de 19 pontos nas AVD revelou ser discriminatória da qualidade do sono de pessoas idosas.

Rotinas de vida diária de crianças portadoras de deficiência : estudos de caso

Dissertação apresentada à Escola Superior de Educação do Instituto Politécnico de Castelo Branco para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Atividade Física, especialização em Desporto Adaptado.

Atividade física amiga do peito

A prática regular de exercícios físicos é comprovadamente capaz de contribuir na prevenção de doenças cardiovasculares, do câncer e de outras doenças crônicas. Envolver-se em atividades físicas, que promovam gasto energético acima do exigido pelas atividades da vida diária, traz muitos benefícios à saúde. O Sedentarismo é reconhecido pela Organização Mundial de Saúde como a quarta causa de morte em todo o mundo. Aumentar o tempo dedicado ao exercício traz maiores benefícios à saúde em geral, além de aumentar a sensação de bem-estar.

Própolis do sudeste e nordeste do Brasil: influência da sazonalidade na atividade antibacteriana e composição fenólica

The composition and biological activities of propolis, a resinous hive product collected by honeybees from various plant sources, depends on various factors such as season and vegetation of the area. The aim of this study was to evaluate the influence of the seasonal effect on the ethanolic extracts of Brazilian propolis (EEP) type 6 and type 12, collected during 6 months in terms of antibacterial activity and phenolic composition. The antimicrobial properties were evaluated by MIC and MBC on S. mutans Ingbritt 1600 and the profile of chemical composition by UV-visible spectrophotometry, HPLC-RF and GC-MS. The results demonstrated that the season in which propolis is collected influences its chemical composition, resulting in modifications in its antibacterial activity.

Alteração da atividade enzimática em organismos aquáticos por poluentes de origem agrícola: uma abordagem geral e sobre a suscetibilidade da fosfatase ácida

The input of agrochemicals in the aquatic compartment can results in biochemical injuries for living organisms. In this context, the knowledge of alterations of enzymatic activities due the presence of agriculture pollutants contributes for the elucidation of the mechanisms of toxicity, implementation of economic methods for monitoring purposes and establishment of maximum allowed concentrations. In the present work, the above considerations are discussed, and data concerning changes in enzymatic function by pesticides and fertilizer contaminants are reviewed. Also, we focused on the acid phosphatase due its susceptibility to several pollutants and diversity in cellular functions.

Glicoproteína-P, resistência a múltiplas drogas (MDR) e relação estrutura-atividade de moduladores

Multidrug resistance, MDR is a major obstacle for cancer chemotherapy. MDR can be reversed by drugs that vary in their chemical structure and main biological activity. Many efforts have been done to overcome MDR based on studies of structure-activity relationships and in this review we summarize some aspects of MDR mediated by P-glycoprotein (P-gp), as the most experimentally and clinically tested form of drug resistance. The most significant MDR mechanisms revealed until now are shortly discussed. Physicochemical and structural properties of MDR modulators, measures of the MDR reversal, and QSAR studies are included.

Estudo químico de Sinningia allagophylla guiado por testes de atividade antiproliferativa

Activity guided fractionation of Sinningia allagophylla (Mart.) Wiehler ethanolic extract yielded a new benzochromene 8-methoxylapachenol, besides seven known compounds: lapachenol, sitosteryl oleate, sitosteryl linoleate, stigmasteryl oleate, stigmasteryl linoleate, dunniol and tectoquinone. Extract, fractions, and compounds lapachenol, 8-methoxylapachenol, and dunniol were tested in vitro against human cancer cell lines U251 (glioma, CNS), MCF-7 (breast), NCI-ADR/RES (drug-resistant ovarian), 786-0 (kidney), NCI-H460 (lung, no small cells), PC-3 (prostate), OVCAR-3 (ovarian), HT-29 (colon), K562 (leukemia) and against VERO, a normal cell line. The most active compound was dunniol, which inhibited the growth of U251, MCF-7, NCI-ADR/RES, OVCAR-3 and K562 cell lines.

Atividade de extratos de Arrabidaea chica (Humb. & Bonpl.) Verlot obtidos por processos biotecnológicos sobre a proliferação de fibroblastos e células tumorais humanas

Arrabidaea chica (H&B) Verlot is a plant popularly known as Pariri and this species is a known source of anthocyanins, flavonoids and tannins. This report describes an approach involving enzymatic treatment prior to extraction procedures to enhance A chica crude extract anticancer activity. Anticancer activity in human cancer cell lines in vitro using a 48 h SRB cell viability assay was performed to determine growth inhibition and cytotoxic properties. The final extraction yield without enzyme treatment was higher (24.28%) compared to the enzyme-treated material (19.03%), with an enhanced aglycones anthocyanin ratio as determined by HPLC- DAD and LC-MS with direct infusion.

Avaliação da qualidade de vida em pacientes idosos um ano após o tratamento cirúrgico de fraturas transtrocanterianas do fêmur

OBJECTIVE: Evaluate the impact that trochanteric hip fractures produce on life quality of elderly patients, treated surgically, during one year of monitoring. METHODS: Were selected 73 elderly with transtrochanteric femur fracture, aged equal or over than 65 years and of both sexes. All participants underwent a standardized questionnaire which obtained information on lifestyle habits, functionality, physical activity, ambulation and cognitive state. Were excluded patients who died, not walking, with neurological diseases and pathological fractures. RESULTS: The average age was 80.17 ± 7.2 years and 75% was female. When comparing the summation of activities of daily living (p = 0.04) and instrumental daily living (p = 0.004) obtained before and after fracture, the patients become more dependent after fracture. Activities of daily living that worsened after fracture were bathing (p = 0.04), toileting (p = 0.02) and dressing (p = 0.04). All instrumental activities of daily living showed a significant difference, with functional dependence after fracture, increased need for walking aid (p = 0.00002), aged (p = 0.01) and not doing housework (p = 0.01). The low score on the test Minimental was associated with a greater dependence to perform activities of daily living before (p = 0.00002) and after (p = 0.01) fracture. CONCLUSION: After a year, activities of daily living that depended on the lower limbs worsened significantly, all instrumental activities of daily living were significantly worse in more than 50% of patients and more than half of patients who walked without support lost this ability.

Influência da atividade física na qualidade de vida e auto-imagem de mulheres incontinentes

Our aim was to verify the influence of a physical activities proposal in the quality of life and self image of incontinent women. This study was comparative and exploratory and was developed in 16 weeks. Thirty-seven women with and without urinary incontinence (IU) participated in the study. After the study, significant improvement in general health perception (p < 0.001), UI impact (p = 0.035), physical limitations (p = 0.015), personal relations, (p = 0.048), sleep and disposition (p = 0.012) and concerned with the gravity measurements (p = 0.011) was observed. Concerning self image, alterations in appearance were not observed; however, concerning body satisfaction, the women felt less satisfied with their bodies (p = 0.007). There was a reduction in the number of regions where they felt pain (p = 0.0003) and that they did not like (p = 0.0017). In conclusion, the Physical Education professionals using a systematized and integrated physical activities program can lead the women with IU to significant improvement in the perception of their quality of life and health concerning their self image with improvement of the IU symptoms and reduction of frequency and amount of urinary loss.

PREDIÇÃO DA ATIVIDADE DE ÁGUA E RELAÇÃO ENTRE A ATIVIDADE DE ÁGUA E A DEPRESSÃO DO PONTO DE CONGELAMENTO DE SUCOS DE FRUTAS

This work proposes to determine the water activity and the freezing point depression of tangerine, pineapple and lemon juices at various concentrations (10-55oBrix) and to achieve a correlation between these properties. The freezing point depression was determined with a LAKTRON cryoscope and common laboratory materials. The water activity was determined with a DECAGON CX-2 hygrometer in the temperature range of 15 to 30oC. With the results, the adjustment to CHEN (1987) water activity prediction equation to non-electrolyte mixtures was verified, through the calculation of the variation coefficient (CV). Being CV smaller than 3% for the proposed model, it can be said that the experimental data have adjusted well to the prediction equation. The water activity and the freezing point depression was correlated for tangerine, pineapple and lemon juices and r2 values were higher than 99%. Therefore, it is possible to obtain the water activity by knowing the freezing point depression of studied juices.

Qualidade de vida de portadores de Diabetes Mellitus tipo II frente às oscilações no nível de atividade física, aspectos socioeconômicos e presença de comorbidades

Universidade Estadual de Campinas . Faculdade de Educação Física

Qualidade de vida e nivel de atividade fisica de funcionarios de empresa de tecnologia da comunicação

Universidade Estadual de Campinas . Faculdade de Educação Física

Influencia de diferentes informações quanto ao tempo de realização do exercicio sobre a atividade eletromiografica e consumo de oxigenio em ciclistas

Universidade Estadual de Campinas . Faculdade de Educação Física