Endoscopic band ligation without resection in selected patients for small and superficial upper gastrointestinal tract lesions

Background and aim: The aim of this study was to evaluate the efficacy of endoscopic band ligation (EBL) in carefully selected patients who would benefit from this method of resection. Methods: Patients with early upper gastrointestinal and small (< 15 mm) lesions treated with EBL (Duette® Multi-Band Mucosectomy) were prospectively recruited and retrospectively analyzed between 2010 and 2015. All cases were discussed in a multidisciplinary cancer committee and it was concluded that, owing to patient conditions, surgery was not possible and that not conducting histology would not change the clinical management. A first endoscopic control with biopsies was planned at 4-8 weeks. If there was no persistence of the lesion, new controls were programmed at 6 and 12 months. Results: The group (n = 12) included 5 esophagus lesions (adenosquamous carcinoma, n = 1; carcinoma squamous, n = 2; adenocarcinoma, n = 2); 4 gastric lesions (high grade dysplasia, n = 1; adenocarcinoma, n = 2; neuroendocrine tumor [NET], n = 1), and 3 duodenal lesions (NETs) (n = 3). The mean tumor diameter was 9.6 ± 2.8 mm (range 4-15). Only one minor adverse event was described. At first follow-up (4-8 weeks), there was 91.6% and 75% of endoscopic and histological remission, respectively. At 6-month follow-up there was 70% of both endoscopic remission and negative biopsies. And at 12 months, there was 100% and 75% of endoscopic and histological remission, respectively. Persisting lesions were T1 cancers. The median follow-up was 30.6 months. Conclusion: EBL without resection is an easy and safe technique that should be considered in patients with multiple morbidities and small superficial UGI lesions.

MODELO PARA EL ANÁLISIS DEL FORTALECIMIENTO SOCIOECONÓMICO DE LAS MIPYMES EN COSTA RICA

Resumen El efecto de múltiples variables sobre el bienestar social y económico en las pequeñas y medianas empresas puede ser analizado tomando en cuenta las condiciones sistémicas en el modelo propuesto. Este artículo ofrece un marco teórico o modelo para comprender y explicar la relación entre las variables independientes tales como el crédito, mercados, empresariedad, entre otras, y la variable dependiente tal como los ingresos, la producción o el empleo. El propósito fundamental es organizar la mayoría de variables para determinar porqué los ingresos y el empleo no es sostenible par alas pequeñas y medianas empresas. Por lo tanto, factores sociales, económicos así como culturales e institucionales han sido incluidos en el análisis. El modelo desarrollado puede ayudar a mejorar el diseño de estrategias para lograr el éxito de las pequeñas y medianas empresas y el marco de política pública para el gobierno en Costa Rica.   Abstract The effect of multiples variables on the social and economic welfare in the Small and medium size enterprises can be analized taking in account systemic conditions in this model.This paper offers a theoretical framework or model to understand and explain the relationship between independent variables such as credit, markets, entrepreneurship, among others, and dependent variable such as incomes, production or employment rate. The main idea is organize the all variables to determine why the income or employment level is not sustainable for SMEs. Therefore, social and economic factors as well as cultural and institutional components have been included in this analysis. The developed model can help to improve design and management of competitiveness strategies for SMEs and policy framework for the government in Costa Rica.

O papel da partilha de conhecimento na relação entre confiança e compromisso organizacional

Mestrado em Ciências Empresariais

A indústria hoteleira do Algarve: uma análise de dados em painel da estrutura de capital

Dissertação de Mestrado, Finanças Empresariais, Faculdade de Economia, Universidade do Algarve, 2015

Determinantes financeiros da estrutura de capital das PME industriais portuguesas ao longo dos ciclos económicos

Dissertação de Mestrado em Gestão Empresarial. Faculdade de Economia, Univ. do Algarve, 2004

Princípios de responsabilidade social : como vão as coisas nas pequenas e médias empresas do Portugal periférico?

O presente trabalho aborda a problemática da Responsabilidade Social Empresarial no âmbito das Pequenas e Médias Empresas, e corresponde à dissertação exigida para conclusão do Mestrado em Gestão da Universidade de Évora. Analisa-se o 'estado da arte' naquela matéria, verifica-se que o problema da responsabilidade social não é uma novidade das últimas décadas e apresenta-se o resultado da aplicação no Alentejo de um inquérito utilizado no Brasil pela Ethos-Sebrae para medir a consciencialização das PME relativamente às questões da Responsabilidade Social. Conclui-se pela necessidade de implementar acções de formação, sensibilização e assessoria, junto dos pequenos empresários, através de Instituições sem fins lucrativos. ABSTRACT: This work is focused on the subjects of small and medium size enterprises concerning the Corporate Social Responsibility (CSR), and it is the required exposition for the conclusion of the Master’s degree in Management given by the University of Évora. lt contains the analysis of the "state of the art" in this subject, confirming that the problem of social responsibility is not a new concern in the last decades. Besides it presents the result of the application in Alentejo of an inquire used in Brazil by Ethos- Sebrae to measure the level of conscience of the small and medium size companies in what concerns to their social responsibility. lt comes to the conclusion it is required that non-profit institutions should implement workshops, actions of awareness and advisory directed to small enterprisers.