942 resultados para MEIOTIC SEGREGATION


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Nowadays, there is a tourism phase in the city of Natal/RN called internationalization of tourism , which shows a tourism model with a planning and an administration, based on the needs of the visitors. Such process shows that the production as well as the reproduction of the city spaces with the goal of favor tourism excludes of its composition the effective participation of local subjects. Thus, the research is a result of the perception of tourism as an activity with a meaningful power of transformation of the social and natural space taking into account the low participation of the residents in the decisions of the tourism activities in the city of Natal/RN. Despite that reality, it is possible to note Natal that civil society, starts to mobilize its citizens trying to develop collective actions to low the negative impacts caused by the bad planning as wells not efficient tourism administration, trying to put in action the right of the local population to take part in the decisions of the city activities. Having this panorama as background, this paper aims at investigating in which way the mobilizing action of the social capital in Natal has contributed to change the spatial production which is part of the process of expansion of tourism in Natal/RN? The research presents a temporal picture which starts in the year of 1980, when occurs the first effective state intervention aiming to develop tourism in the capital, taking into account an analysis of 2012. Concerning the spatial picture, the research investigates the beaches of Natal which concentrates criteria and actions such as: visitation, tourism appeal and focus of investments, highlighting the following beaches: Ponta Negra, Areia Preta, Praia dos Artistas, Praia do Meio, Praia do Forte and Redinha. This study is of a descriptive and exploratory nature concerning its goals. With respect to the treatment of its object it is a qualitative research. The data was collected through structural interviews, with open questions. Regarding the methodological choices, it was used the content analysis proposed as well as the collective discursive subject methodology. The results show that there´s not yet in Natal a meaningful social capital related to tourism, capable to change the spatial production related to the activity. It should be stressed that Natal social capital presents difficulties concerning the incentive to trust, spontaneous cooperation and the civic participation, which are the foundation for the development of an effective social capital, which makes it harder for a more expressive articulation in the reality in Natal/RN. It should be stressed, as an answer to the research questions, that tourism in Natal/RN is represented by social and spatial segregation. In other words it emphasizes mainly the action of hegemonic agents (State and market), leaving little room for the participation of society. It can be noticed that the actions related to tourism in Natal keeps the popular participation out of the way. Thus, it can be said that the social capital in Natal/RN does not yet contribute to a more fair spatial production related to the expansion of the tourism as well as the well being of the population of Natal/RN. In conclusion, it should be taken into account that this participation do exists but not in a meaningful way. In other words, it´s not enough yet to cause meaningful changes in the actions which tourism needs nowadays in Natal/RN

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This study emerges and develops, from a note by Italo Calvino, who in his novel Invisible Cities advised to avoid saying "that sometimes different cities follow on the same site and with the same name, born and die without knowing, without communication among itself ". The research with a transdisciplinary work ( using elements of sociology, anthropology, geography and communication) made a reflection about segregation and tourism: poverty-richness, center-periphery, tradition- spectaclezation , the visitor-visited maping the touristic circuit and discussing about the phenomenon on the real city and touristic place: Natal and the "Sun City" - Rio Grande do Norte, studying videos produced by residents (documentary) and tourists ( posted on the Internet). Doing a comparative analysis between the realities of these two subjects (resident and tourist), the research found few similarities, many differences on the urban experience, with the existence of two distinct realities (tourist region X the periphery region). Based on theory of phenomenology, social representation, and using content analysis of film, it was noted that promotes to the visitor a trip segmented and disintegrated to daily life, culture and contact with the resident. Resident that, in largely part, lives in a unattended area, with no prospect of life (represented by Novo Horizonte Community). The confinement and segregation occurs even in his moments of leisure and cultural expressions (represented by Redinha‟s Beach), because the private an public leisure areas of tourism indirectly prevent access by people who can not contribute to the consumption on this places. This papper concluded that the tourism in Natal is an activity-phenomenon that directs and focuses on public investments for infrastructure tourist region (Ponta Negra Beach), in detriment of the poorest and periphery areas of the city

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The genome of all organisms is subject to injuries that can be caused by endogenous and environmental factors. If these lesions are not corrected, it can be fixed generating a mutation which can be lethal to the organisms. In order to prevent this, there are different DNA repair mechanisms. These mechanisms are well known in bacteria, yeast, human, but not in plants. Two plant models Oriza sativa and Arabidopsis thaliana had the genome sequenced and due to this some DNA repair genes have been characterized. The aim of this work is to characterized two sugarcane cDNAs that had homology to AP endonuclease: scARP1 and scARP3. In silico has been done with these two sequences and other from plants. It has been observed domain conservation on these sequences, but the cystein at 65 position that is a characteristic from the redox domain in APE1 protein was not so conservated in plants. Phylogenetic relationship showed two branches, one branch with dicots and monocots sequence and the other branch with only monocots sequences. Another approach in order to characterized these two cDNAs was to construct overexpression cassettes (sense and antisense orientation) using the 35S promoter. After that, these cassettes were transferred to the binary vector pPZP211. Furthermore, previously in the laboratory was obtained a plant from nicotiana tabacum containing the overexpression cassette in anti-sense orientation. It has been observed that this plant had a slow development and problems in setting seeds. After some manual crossing, some seeds were obtained (T2) and it was analyzed the T2 segregation. The third approach used in this work was to clone the promoter region from these two cDNAs by PCR walking. The sequences obtained were analyzed using the program PLANTCARE. It was observed in these sequences some motives that may be related to oxidative stress response

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This work exposed desired to investigate the function of evolution of closed allotment, of market of the earth and of forms of extraction of the lace of earth, in the processes capitalist production of urban space in Nova Parnamirim, community of Parnamirim/RN. This tendentious urbanization were marked for an expressive increase of number of horizontal and vertical closed residences joint ownership concerning at social groups more privileged financial position. Go after, set off, a temporal investigation, based in the forms of appropriation of space in the middle intermediate by action of the several producers agent of capitalist capital. This way, make necessary understand the past of local structure earth, in order that to make possible analyze the beginning of the process. Not enough, appealed the publics institutions as immobile notary s office and secretary municipal for to collect the more important information, and in the field through of application of formulary together the population of ward, in order that of examine the motivation of residential establishment inside. Make this, confirmed that the actual spatial organization of ward of Nova Parnamirim started of two allotments: the Vale do Pitimbú Park and Eucaliptos Park, both divided in several little allotments. Before of begin the ward, allotments reproduced set off from that native has been consigned during the 80, 90 decade s and begin the actual century, resigning a complicated urban structure earth, dynamized by exploration of a promising residential area. Leashed of this, confirmed the installation of logic of segregation and auto-segregation conducted by an immobile market which exclude the poor class and absorb rich class, motivate by perspective of obtaining of urban lace of earth by immobile promoter. However, perceived that the growth this market was promoted by migration of groups of capital, interior of state and others regions of country. Not distant, horizontal and vertical closed residences represent production forms of a new form of residence, corresponding the pattern architectonic as socioeconomics, strengthened by ideal of security, quality of life, necessity of reclusion and of proximity of Natal. Is in the capital which this individual found possibilities of attend satisfactory minimum of yours necessity in relation a consumption of bens and specialized and specifics services. Before this qualitative perceive that the social and spacial differential of Nova Parnamirim was the responsible by soil and habitation valorization of ward, that reinforce the promotion of segregation and of auto-segregation, and consequently, of capitalist reproduction of urban space

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The process of urbanization of Natal city has been going in the last years by importants changes, mainly, because we can observe the development of a new kind of housing: the horizontal closed condominiums, from 1995 began to expand quickly on the city. In this way, the present study has as objective analyse the expansion of the horizontal closed condominiums on the urban area of Natal. Emphasizing the sociogeographic changes that these ventures engender. For this, we have done a research that was based on quantitative procedures, however, preferring a qualitative approach. So, data were gathered from sources and procedures: the first, we performed a literature search and document on issues related to the relevant issues in libraries, public and privates institutions; The second, in accordance with the procedures, or the production of informations, performed enterview and implemetation of questionnaires with key stakeholders involved with the expansion of horizontal condominiums in Natal. Within this perspective, our research showed that the expansion of demand in the city, the existence of volume of land in areas suitable for the production building, the formation of capital property, the appearance of new points of modern consumption, the actions of the state and the low cost of production of these enterprises, are factors that have been decisive in the expansion of the horizontal condominiums in Natal. Also, we can observe that the process of production of the urban space from the horizontal condominiums comes in providing the redefinition of land use in areas that appear, because they expand into outlying areas of Natal, changes in its structure and its pattern of socio segregation, observing that the condominiums put the diferents social groups living side by side, but not mantaining relationships among them, the emergence of spaces to homogenization, the fragmentation of the urbanization, the privatization of the city and several environmental problems. In short, we believe that the horizontal expansion of condominiums is enabling a number of social changes to Natal city

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This dissertation deals with the study of the faces of social exclusion at present, through a spatial section constituted of a subnormal area (the Community Africa), which groups these aspects in a limited, but revealing, context regarding such problems. Through the following chapters, inequality, exclusion, segregation, the socioeconomics of the Community Africa, and the environmental impacts identified in this community are discussed. At the end of this piece of work, alternatives of possible solutions to the community area pointed, with also the discussion of propositions related to the questions concerning the mitigation of the most relevant problems

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This present work has as its objective the analysis of transformations relating to the production processes in the Southern littoral urban space of the city of João Pessoa PB. The research estimated that the urban space is the product, means and condition of the society which produces it. The object-area of this inquiry is constituted of five districts: Altiplano Cabo Branco, Portal do Sol, Ponta do Seixas, Penha and Costa do Sol. The urban expansion which occurs in this area is characterized by the appearance of sufficient contradictory space phenomenona. On the other hand, the launching of real estate products such as the horizontal closed condominiums, directed towards the upper class, and the occurrence of areas of irregular occupation, inhabited by lower socioeconomic class and with a great lack of infrastructure and basic urban services, revealing the social contradictions. Due to this, processes such as auto-segregation and segregation imposed beyond the precarious and delinquent inclusion, has become the determining characteristic of this part of the city in analysis. The study also takes into account the appreciation of the new urban environmental zoning of Altiplano do Cabo Branco and from this moment on, start the discussion about the tendencies of urban expansion in this area, due to the interests and strategies of the real estate sector and the prominent role of the government in the current valorization process of urban soil of the area. The presence of residuals of agricultural businesses indicates a typical picture of the peri-urban areas configuring what we observe today at the Southern littoral of João Pessoa

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This thesis analyzes another side of Potiguar tourism , the unplanned side, neglected and kept out of touristic activities: excursionism, a leisure practice enjoyed by tourists with low consumer power, and who are commonly referred by the pejorative term farofeiros (picnic lovers). The geographic research sites considered for this study include Arituba, Boágua and Carcará lakes in Nísia Florest, Rio Grande do Norte, where on Sundays and holidays the arrival of hundreds of excursionists, from around the metropolitan region of Natal, from surrounding municipalities, and neighboring States, such as Paraíba and Pernambuco, can be observed. The objective of this study is to analyze the appropriation of the physical site by the practice of excursionism, focusing on its relation to other social agents that also appropriate a designated touristic area. The theoretical discussion considers the use of the space by the touristic leisure practice and the appropriation by distinct social agents, using categories of analysis, such as, production of the space, territory and leisure. The field work was completed with interviews and questionnaires administered to excursionists, excursion organizers, local merchants, representatives of the public setor from the municipalities, and professional dune buggy drivers; besides this, photos, informal dialogue and field observations were important methodological instruments used. From the data, statistical analysis and the development of thematic maps demonstrating the established flux between excursionists and the segregated activity were done. With this research, one can affirm that the practice of excursionism is neglected by the public sector, contrary to the intention of the hegemonic agent‟s intentionality present in this touristic territory which aim at the development of a lucrative activity, geared toward tourists with greater spending power. This ignored and neglected faction of Potiguar tourism is considered poor or dirty , and generate conflicts among the distinct social agents: tourists, the market and the public sector, simultaneously peaking interest, which is then appropriated by the informal sector and formal economy. Excursionism is an expressive phenomenon, a socially relevant practice, enjoyed by citizens of the working class who, in order to have a day of leisure, use alternative consumer practices and subvert various strategies of segregation that are imposed within these tourist areas, behavior that, in part, justifies the nickname, picnic lovers , given to these tourists

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This paper aims at analyzing the dynamics of informal housing in Mãe Luiza, in the context of real estate valuation of the city of Natal/RN, which, like any other urban center, has problems related to access to urban land, which increasingly more is appreciated due to their scarcity and, consequently, has led to the segregation of urban spaces. Recently, the informal housing market has received special attention by scholars who wish to discuss the production of space and ways of access to urban land and housing, especially for those disadvantaged by the housing policies of the government where these exist. When talking about the housing market, we are automatically referring to concepts or categories intrinsic to the existing mode of production in our society - the capitalism. Thus, the categories: income, value (use and exchange), commodity, capital, profits and capital gains, along with other important concepts as well as land use (urban) and real estate agents are of great relevance to discussion we intend to do within the context of production space

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The genesis of the research emerges from reflection about the space dynamics of the capital and to the capital. The expansion and the incorporation of territory for capital reveal, in part, strategies of the capitalism production way, which shows the search for accumulation conditions, expanding the alternatives of territory use that is, nowadays, selective and uneven. The present work verified the mechanisms where the capital imposes its practices through the agrarian structure and the valuation of land market, meaning, in our knowledge, that the reproduction of inequalities is showed, many times, by the wide land speculation and the fast land valuation. For this, the snip space will be the Sibaúma community, belonging to Tibau do Sul district, located in Rio Grande do Norte state. It‟s a rural area that has, gradually, changing through the advent of urban characteristics, given the association of public and private investments, both domestic and international. Through the empirical observations, inside the Sibaúma community, it was found expansion strategies, incorporation and appropriation of territory by capital. As a result of this practice, it‟s occurring the land valuation and the presence of a process of socio-spatial segregation, through the encouraging the opening of new subdivisions, mainly for construction of second homes and tourism enterprises in order to meet the demand of a higher socioeconomic level. The areas still available in Sibaúma, constitute into a reserve of value for the achievement of capitalist rent, being a mechanism of capital reproduction. In this way, to studying the socio-spatial transformations, caused by spatial valuation, we turn to the project of social space designed by Santos(2006), from the perspective of capitalist production of space, by understanding the historical process of formation, the mechanisms and the actions of social actors that produce and consume space

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The speed and fluidity are basic requirements for reproduction of big capitalism. Thus, the objects and their actions seek to meet these aspirations of hegemony. And among these objects, there is emphasis on the road systems of movement, made up of bridges, viaducts and tunnels, engineering works that cater to this nee increasingly evident in the current period technical-scientific-informational. So on this premise, it becomes apparent that these objects reflect the technical So on this premise, it becomes apparent that these objects reflect the technical space constitution of Natal, capital of Rio Grande do Norte, where the road systems of movement help to understand the process of fragmentation and and spatial segregation of Natal, accelerated in the late twentieth century. Using the analysis as a tool for urban legislation developed in the capital of RN by the municipal administration, this paper seeks to understand, through a matrix of periodization, as these systems move natalense shaped space and which exists for the hegemonic logic limit the formation and location of each of these systems move road, particularly as it concerns the relationship between these and the expansion of opportunities for certain fluidity between the road systems of movement (fixed), their flow

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It analyzes the production of the space of the North Zone of Natal/RN, of the beginning of its formation - decade of 1970 - a present time, under the optics of the urban planning and of the administration of the territory. Inside of that path, it examines the interests that orientated the "creation" of the referred space, as support to the process of urban planning and of administration of the territory; as well as the recent processes that evidence a new partner-space dynamics, which is configured, now as an incipient insert of the North Zone to the context natalense urban-space, now as a "reedition" of its report process of partner-space segregation. It stands out that, while in the beginning of the formation of the North Zone, the State was made the main actor, making possible the expansion of the capital in the north sense of the city of Natal, through the implantation of the Industrial District of Natal (DIN) and of the expansion of the habitational politics of the House of Financial System (SFH); at the present time, the new space processes are configured through the economical inclination, through expansion of the tertiary section in the city of Natal. It is based in bibliography regarding the theme in focus, in primary and secondary sources, as well as in processes and forms that were unchained in the North Zone along the research. It analyzes the North Zone then in its group, the one that makes possible apprehend the inherent conflicts to the process of production-appropriation of the urban space, for the several social actors - the State, the capital and the society - that dispute the control of the production of the space according themselves their interests

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Background: Oculocutaneous albinism (OCA) is an autosomal recessive hereditary pigmentation disorder affecting humans and several other animal species. Oculocutaneous albinism was studied in a herd of Murrah buffalo to determine the clinical presentation and genetic basis of albinism in this species.Results: Clinical examinations and pedigree analysis were performed in an affected herd, and wild-type and OCA tyrosinase mRNA sequences were obtained. The main clinical findings were photophobia and a lack of pigmentation of the hair, skin, horns, hooves, mucosa, and iris. The results of segregation analysis suggest that this disease is acquired through recessive inheritance. In the OCA buffalo, a single-base substitution was detected at nucleotide 1,431 (G to A), which leads to the conversion of tryptophan into a stop codon at residue 477.Conclusion: This premature stop codon produces an inactive protein, which is responsible for the OCA buffalo phenotype. These findings will be useful for future studies of albinism in buffalo and as a possible model to study diseases caused by a premature stop codon.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)