Desenvolvimento de uma nova sistemática para centragem e alinhamento da plataforma giratória R-9350 na mandriladora CNC PAMA SPEEDRAM 3000

In heavy machining industries, a critical point that must be taken into account is setup. Because the characteristics of machine tools and parts to be machined, usually pieces robust and large, the preparation of these parts must be made accurately for machining has a good result as planned. As a result of the difficulty raised in the setup machining of heavy parts, companies in this segment seek alternatives to reduce the unproductive time caused by setup and optimize machining processes. One way was found that these companies create operating instructions that describe and standardize the operation between its employees, as well as deploy a control machining times to measure the unproductive time caused by the setup. This work studied a new system for the realization of centering and alignment of Rotating Deck R-9350 in CNC Milling Machine PAMA Speedram 3000, in Liebherr Brazil company. The part Rotating Deck R-9350 is a critical part in which its machining in PAMA Milling Machine is made in three phases and their setup times are quite high and involve stopping the machine. It has been tested and proposed a solution to the realization of this part of the setup without the use of the machine, but of the measuring instrument three-dimensional Laser tracker, with which the machine continued to work, while he was in the centering and alignment of other parts. It was noted that the instrument technically attended the need and it was possible to perform this operation more accurately

Melhoria do processo de reparo por meio da redução de Lead Time em uma empresa de som automotivo

The constant search for improvement and survival of the companies makes essential the utilization of cost reduction strategies and resources optimization. This study had as its objective the utilization of Lean Manufacturing tools for the repair process lead time reduction, in a car audio manufacturer. Performing an action research, the major problems were studied, such as the potential causes and the possible improvement activities, using the DMAIC methodology. An action plan was developed for all involved processes and, as a result, the objective was reached by making a direct impact on the customers’ satisfaction and adding a competitive differential for the company

Influência do enriquecimento ambiental nos padrões comportamentais de Galictis cuja, furão-pequeno, mantidos em cativeiro no zoológico municipal de Piracicaba, SP

Currently zoos and management centers are valuable tools in the maintenance and study of various species. Studies of behavior of captive animals contribute to the improvement of management techniques and the well - being of themselves, encouraging captive breeding and reintroduction also to the natural environment . One of the ways to increase the levels of well-being is the use of environmental enrichment techniques that provide necessary incentives for the welfare of both physical and psychological captive animal . The aim of this study was to identify the types, frequencies and intensities of behavior displayed by three individuals of the species Galictis cuja, belonging to the family Mustelidae and popularly known as lesser grisson , which are captives in municipal zoo in Piracicaba , SP . In addition to evaluating the influence of environmental enrichment techniques on these behavioral parameters. The animals had their behaviors recorded in ethograms through the focal sampling method , 40 hours per person , totaling 120 hours of observation . Were introduced four environmental enrichment techniques related to physical environment, nutrition , perception and cognitive stimulation . At the end, the results of observations before and after the introduction of enrichment techniques were compared and it was possible to observe significant changes in behavior such as run , walk and scratching . The animals were more active and spent longer visible during the day, the enrichment also increased the frequency of social behaviors and the end of the work occurred even attempted copulation , thus showing that the enrichment exerted a positive influence on the behavioral patterns of lesser grisson (Galictis cuja)

PGCP - Plataforma para Gerenciamento Colaborativo de Projetos

Collaborative Systems are designed to support individuals in order to solve a problem together, or cooperatively (or collaboratively). Such systems have the advantage of not requiring the presence in the same location of the participants. The basis of any Collaborative System is communication, where users interact with each other in order to exchange information. Communication among individuals is accomplished through collaborative tools such as chat, email, document repository, etc.. Using these tools, companies can reduce operational costs, saving on travel and accommodation of its employees to attend meetings. The project members only need a computer with internet access to use collaborative tools. Project management is essential to the quality of the nal product. To perform a proper management, methodologies must be applied using methods, tools and procedures. There are some phases that are considered generic for all software process models, they are: de nition, development, maintenance and activity to support the software process. In this paper is described a platform for project management using the concepts and features of Collaborative Systems. The goal of this platform is to unify various collaborative tools (such as chat and document repository) in a project management system. Using the system, it becomes possible to manage projects, and the ability to maintain an active constant communication between members of each project

Energy and protein requirements of male and female saanen goats

Pós-graduação em Zootecnia - FCAV

A concepção de ferramentas de tradução como dinamizadoras da produção tradutória e seus reflexos para a prática

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Impact of the medicine Hydroxyurea on reproduction and development, using Drosophila melanogaster as a model organism

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Effect of diets with varying starch content on muscle glycogen concentrations during training and replenishment after highintensity exercise

Pós-graduação em Zootecnia - FCAV

Remodeling of cortical and corticocancellous fresh-frozen allogeneic block bone grafts - a radiographic and histomorphometric comparison to autologous bone grafts

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Effect of chlorhexidine gluconate on porosity and compressive strength of a glass ionomer cement

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Expressão diferencial de mRNA em células de cultivo infectadas ple herpesvírus bovino 5

Pós-graduação em Medicina Veterinária - FMVZ

MicroRNA-499 expression distinctively correlates to target genes sox6 and rod1 profiles to resolve the skeletal muscle phenotype in nile tilapia

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Isoflurane and propofol contribute to increasing the antioxidant status of patients during minor elective surgery: a randomized clinical study

Isoflurane is a volatile halogenated anesthetic used especially for anesthesia maintenance whereas propofol is a venous anesthetic utilized for anesthesia induction and maintenance, and reportedly an antioxidant. However, there are still controversies related to isoflurane-induced oxidative stress and it remains unanswered whether the antioxidant effects occur in patients under propofol anesthesia.Taking into account the importance of better understanding the role of anesthetics on oxidative stress in anesthetized patients, the present study was designed to evaluate general anesthesia maintained with isoflurane or propofol on antioxidant status in patients who underwent minimally invasive surgeries.We conducted a prospective randomized trial in 30 adult patients without comorbidities who underwent elective minor surgery (septoplasty) lasting at least 2 h admitted to a Brazilian tertiary hospital.The patients were randomly allocated into 2 groups, according to anesthesia maintenance (isoflurane, n = 15 or propofol, n = 15). Peripheral blood samples were drawn before anesthesia (baseline) and 2-h after anesthesia induction.The primary outcomes were to investigate the effect of either isoflurane or propofol anesthesia on aqueous plasma oxidizability and total antioxidant performance (TAP) by fluorometry as well as several individual antioxidants by high-performance liquid chromatography. As secondary outcome, oxidized genetic damage (7,8-dihydro-8-oxoguanine, known as 8-oxo-Gua) was investigated by the comet assay.Both anesthesia techniques (isoflurane or propofol) for a 2-h period resulted in a significant decrease of plasma α-tocopherol, but not other antioxidants including uric acid, carotenoids, and retinol (P > 0.05). Propofol, in contrast to isoflurane anesthesia, significantly increased (P < 0.001) anti-inflammatory/antioxidant plasma γ-tocopherol concentration in patients. Both anesthesia types significantly enhanced hydrophilic antioxidant capacity and TAP, with no significant difference between them, and 8-oxo-Gua remained unchanged during anesthesia in both groups. In addition, both anesthetics showed antioxidant capacity in vitro.This study shows that anesthesia maintained with either propofol or isoflurane increase both hydrophilic and total antioxidant capacity in plasma, but only propofol anesthesia increases plasma γ-tocopherol concentration. Additionally, both types of anesthetics do not lead to oxidative DNA damage in patients without comorbidities undergoing minimally invasive surgery.

Predicting embryo presence and viability

Pregnancy establishment, followed by birth of live offspring, is essential to all mammals. The biological processes leading up to pregnancy establishment, maintenance, and birth are complex and dependent on the coordinated timing of a series of events at the molecular, cellular, and physiological level. The ability to ovulate a competent oocyte, which is capable of undergoing fertilization, is only the initial step in achieving a successful pregnancy. Once fertilization has occurred and early embryonic development is initiated, early pregnancy detection is critical to provide proper prenatal care (humans) or appropriate management (domestic livestock). However, the simple presence of an embryo, early in gestation, does not guarantee the birth of a live offspring. Pregnancy loss (embryonic mortality, spontaneous abortions, etc.) has been well documented in all mammals, especially in humans and domestic livestock species, and is a major cause of reproductive loss. It has been estimated that only about 25-30 % of all fertilized oocytes in humans result in birth of a live offspring; however, identifying the embryos that will not survive to parturition has not been an easy task. Therefore, investigators have focused the identification of products in maternal circulation that permit the detection of an embryo and assessment of its well-being. This review will focus on the advances in predicting embryonic presence and viability, in vivo.

Work conditions and occupational health of dentists in Brazilian public health system

Conselho Nacional de Desenvolvimento Ciêntífico e Tecnológico (CNPq)