Live and let die: manipulation of host hepatocytes by exoerythrocytic Plasmodium parasites

The generation of rodent Plasmodium strains expressing fluorescent proteins in all life cycle stages has had a big impact on malaria research. With this tool in hand, for the first time it was possible to follow in real time by in vivo microscopy the infection route of Plasmodium sporozoites transmitted to the mammalian host by Anopheles mosquitoes. Recently, this work has been extended to the analysis of both hepatocyte infection by Plasmodium sporozoites, as well as liver merozoite transport into blood vessels. The stunning results of these studies have considerably changed our understanding of hepatocyte invasion and parasite liberation. Here, we describe the most important findings of the last years and in addition, we elaborate on the molecular events during the intracellular development of Plasmodium exoerythrocytic forms that give rise to erythrocyte infecting merozoites.

Perceptual factors and meanings of symbolic information elements. Volume I, executive summary.

Mode of access: Internet.

Perceptual factors and meanings of symbolic information elements. Volume II, technical report.

Mode of access: Internet.

I. An exposition of the symbolic terms of the second part of Faust. II. How this part thus proves itself to be a dramatic treatment of the modern history of Germany worthy of the genius of Goethe and the life he devoted to the task. (The prologues and first act completely explained; the other acts generally).

Mode of access: Internet.

The psychology of efficiency; an experimental study of the processes involved in the solution of mechanical puzzles and in the acquisition of skill in their manipulation,

Vita.

On Riemann's theory of algebraic functions and their integrals : a supplement to the usual treatises /

Photocopy. [Ithaca, N.Y. : Cornell University Libraries, 1977]--xii, 76 p. on [44] leaves ; 26 x 38 cm. fold. to 25 x 19 cm.

An Historical and literary account of the formularies, confessions of faith, or symbolic books, of the Roman Catholic, Greek, and principal Protestant churches,

Mode of access: Internet.

Use and care of the microscope. Extracts from Manipulation of the microscope.

Mode of access: Internet.

The mechanician, a treatise on the construction and manipulation of tools, for the use and instruction of young engineers and scientific amateurs; comprising the arts of blacksmithing and forging; the construction and manufacture of hand tools, and the various methods of using and grinding them; description of hand and machine processes; turning and screw cutting; and the various details of setting out work incidental to the mechanical engineer's and machinist's art.

Mode of access: Internet.

Anatomical manipulation; or, The methods of pursuing practical investigations in comparative anatomy and physiology.

Mode of access: Internet.

Symbolic teaching; or, Masonry and its message.

Photocopy.

A new key to the exact sciences, or, A new and practical theory by which mathematical problems or algebraic equations of almost every description can be solved with accuracy : and with greater facility and simplicity than they can be by any method that has yet been given by any other author : in which are also introduced, a variety of useful and interesting problems, that have never before been proposed, and which it is believed cannot be solved by any methods or rules except those here laid down /

Mode of access: Internet.

Queen & co.'s manual of engineers and surveyors instruments. Construction, manipulation, care, theory and adjustments.

"First edition."

The amateur microscopist: or, Views of the microscopic world, a handbook of microscopic manipulation and microscopic objects ... illustrated with 247 figures on wood and stone.

Mode of access: Internet.