Memoria del proyecto para la adaptación de la troncalidad del título de Diplomado en Biblioteconomía y Documentación y diseño de un postgrado en gestión de la transferencia del conocimiento en las organizaciones.

Se analizan las asignaturas troncales de la Diplomatura en Biblioteconomía y Documentación para la adaptación al sistema de créditos ECTS, y se diseña un postgrado en Gestión y Transferencia del Conocimiento en las Organizaciones. Para la elaboración del proyecto se establecen dos grupos permanentes de trabajo, uno encargado de la adaptación de las asignaturas troncales y el otro del diseño del postgrado. Se realiza un estudio de la correlación entre las materias troncales de Biblioteconomía y Documentación y las propuestas por el Libro Blanco de la Educación de la ANECA del título de grado en Información y Documentación y se adaptan los contenidos, la teoría, la práctica, el estudio personal y la evaluación a la nueva titulación. Se realiza una propuesta de contenidos en relación a las competencias que el alumno ha de adquirir. En cuanto al diseño del título de postgrado en Gestión y Transferencia del Conocimiento en las Organizaciones, se trata de ofrecer en el ámbito de la administración pública y de las empresas, profesionales que aúnen los conocimientos jurídicos, económicos y de gestión con competencias y habilidades imprescindibles en el contexto de la sociedad de la información. Se realiza un estudio de los perfiles profesionales y competencias genéricas y específicas de la figura del gestor del conocimiento.

Audiovisual sobre el Camino de Santiago.

Se elabora un audiovisual sobre el Camino de Santiago en Castilla y León que permite comprender, tanto el significado del Camino, como de los restos artísticos, culturales, históricos y de alojamiento. La escuela como institución educativa tiene la misión de que sus alumnos conozcan su historia, su cultura y sus avances socializadores. Con el conocimiento del Camino de Santiago en sus diversos aspectos genera contenidos específicos dentro de un aspecto más global que comprende el conocimiento de Castilla y León, su historia, poblaciones, arte, economía, lengua, o literatura. Con este material audiovisual se pretende que los alumnos adquieran los conceptos, procedimientos y actitudes que los ayuden a comprender la realidad económica y social que desde la Edad Media ha generado el Camino. Los objetivos que el material audiovisual se pretenden conseguir son: difundir más de 50 poblaciones castellano-leonesas del Camino de Santiago; distinguir las diversas rutas del Camino; conocer los orígenes de la peregrinación a Santiago; comprender la evolución histórica del camino; ver la influencia del Camino en los aspectos sociales y económicos a que se da lugar; comprender cómo el Camino influye en los asentamientos urbanos; detectar las influencias literarias del Camino; mostrar a los alumnos y demás estudiosos las riquezas artísticas del Camino; conjugar las riquezas artísticas y culturales con los acontecimientos urbanos del Camino; lograr que los alumnos comprendan el significado e importancia del Camino de forma intuitiva, amena y sencilla; y que los alumnos entiendan que en el año que comienza a circular el euro, el Camino Santiago, fue y ha sido un punto importante de unión y relación europea.

Programa de habilidades sociales para mejorar la convivencia.

Monográfico con el título: 'Programas de intervención'. Resumen basado en el de la publicación

El papel del orientador en la convivencia escolar.

Monográfico con el título: 'Aprender a convivir'. Resumen basado en el de la publicación

Estudio de un alumno con s??ndrome de Down en la comprensi??n del sistema de numeraci??n decimal

Resumen tomado de la publicaci??n

La educaci??n ambiental en el Bachillerato : el caso de los docentes que imparten la materia de Ecolog??a, Puebla-Tlaxcala (M??xico)

Resumen basado en el de la publicaci??n

Characterizations of juvenile stages of some semaeostome Scyphozoa (Cnidaria), with recognition of a new family (Phacellophoridae)

Phacellophora camtschatica has long been assigned to the semaeostome scyphozoan family Ulmaridae. Early stages (scyphistomae, strobilae, ephyrae, postephyrae, and young medusae) of the species were compared with those of several other semaeostomes currently assigned to Ulmaridae, Pelagiidae, and Cyaneidae. Juveniles of P. camtschatica did not strictly conform with characters of those of any of these families, and appeared intermediate between Cyaneidae and Ulmaridae. A new family, Phacellophoridae, is proposed to accommodate P. camtschatica.

Food resources influencing the asexual reproductive cycle of coronate Scyphozoa

The study of the strobilation process, a feature unique in the class Scyphozoa, is an issue that helps understanding the patterns of asexual reproduction in sessile invertebrates. Many inducers of asexual reproduction are known for scyphozoans. However, the influence of food resources on the strobilation of Coronate Scyphozoa has never been tested. WO observed strobilation of a large number of polyps of Nausithoe aurea, from a wide sampling area along the South Atlantic coast of Brazil, through the administration of controlled number of hatched nauplii of Artemia franciscana under a previous tested starvation and feeding protocol. The number of strobilations between and within groups varied and the fate and shape of strobilation deviated from the biology reported in the original description. Artificial seawater was used to reduce the influence of dissolved organic matter as likely important alternative nourishment.

Flavonoids and arbutin from Turnera diffusa

The infusion of the aerial parts of Turnera diffusa was phytochemically examined. Chromatographic procedures led to the isolation of a new flavone glycoside, five known flavonoids and p-arbutin. Structures were determined by 1D- and 2D NMR experiments, as well as ES-MS and UV spectra.

Do Staurozoa bloom? A review of stauromedusan population biology

The study of "jellyfish blooms" provides important data toward determining the causes and consequences of these phenomena; however, the definition of "bloom" remains controversial and different concepts have been adopted in recent works. By addressing the biological and convenience definitions, this study tested the adequacy of the different concepts of "blooms" for the Class Staurozoa (Cnidaria). From seasonal monitoring data of some species of Staurozoa, we concluded that stauromedusae bloom if we used the biological concept of "bloom", which considers the life cycle and resulting changes in the abundances of these animals. By contrast, the small, benthic, inconspicuous, and non-harmful stauromedusae do not bloom if we use the convenience concept of "bloom", which constrains the events to those that humans can observe and that cause damage to human activities. In other words, the same group of organisms either is or is not capable of blooming depending on which concept of "bloom" is used. In fact, previous literature has suggested that Staurozoa could not bloom, which indicates that the study of "jellyfish blooms" can be biased, considering convenience rather than biological reasoning.

Mutation Spectrum in the Large GTPase Dynamin 2, and Genotype-Phenotype Correlation in Autosomal Dominant Centronuclear Myopathy

Centronuclear myopathy (CNM) is a genetically heterogeneous disorder associated with general skeletal muscle weakness, type I fiber predominance and atrophy, and abnormally centralized nuclei. Autosomal dominant CNM is due to mutations in the large GTPase dynamin 2 (DNM2), a mechanochemical enzyme regulating cytoskeleton and membrane trafficking in cells. To date, 40 families with CNM-related DNM2 mutations have been described, and here we report 60 additional families encompassing a broad genotypic and phenotypic spectrum. In total, 18 different mutations are reported in 100 families and our cohort harbors nine known and four new mutations, including the first splice-site mutation. Genotype-phenotype correlation hypotheses are drawn from the published and new data, and allow an efficient screening strategy for molecular diagnosis. In addition to CNM, dissimilar DNM2 mutations are associated with Charcot-Marie-Tooth (CMT) peripheral neuropathy (CMTD1B and CMT2M), suggesting a tissue-specific impact of the mutations. In this study, we discuss the possible clinical overlap of CNM and CMT, and the biological significance of the respective mutations based on the known functions of dynamin 2 and its protein structure. Defects in membrane trafficking due to DNM2 mutations potentially represent a common pathological mechanism in CNM and CMT. Hum Mutat 33: 949-959, 2012. (C) 2012 Wiley Periodicals, Inc.

Applicazioni industriali e di ricerca della spettroscopia NIR per la valutazione di indici qualitativi di prodotti alimentari

In the present work qualitative aspects of products that fall outside the classic Italian of food production view will be investigated, except for the apricot, a fruit, however, less studied by the methods considered here. The development of computer systems and the advanced software systems dedicated for statistical processing of data, has permitted the application of advanced technologies including the analysis of niche products. The near-infrared spectroscopic analysis was applied to the chemical industry for over twenty years and, subsequently, was applied in food industry with great success for non-destructive in line and off-line analysis. The work that will be presented below range from the use of spectroscopy for the determination of some rheological indices of ice cream applications to the characterization of the main quality indices of apricots, fresh dates, determination of the production areas of pistachio. Next to the spectroscopy will be illustrated different methods of multivariate analysis for spectra interpretation or for the construction of qualitative models of estimation. The thesis is divided into four separate studies that consider the same number of products. Each one of it is introduced by its own premise and ended with its own bibliography. This studies are preceded by a general discussion on the state of art and the basics of NIR spectroscopy.

Risk profiles and penetrance estimations in multiple endocrine neoplasia type 2A caused by germline RET mutations located in exon 10

Multiple endocrine neoplasia type 2 is characterized by germline mutations in RET. For exon 10, comprehensive molecular and corresponding phenotypic data are scarce. The International RET Exon 10 Consortium, comprising 27 centers from 15 countries, analyzed patients with RET exon 10 mutations for clinical-risk profiles. Presentation, age-dependent penetrance, and stage at presentation of medullary thyroid carcinoma (MTC), pheochromocytoma, and hyperparathyroidism were studied. A total of 340 subjects from 103 families, age 4-86, were registered. There were 21 distinct single nucleotide germline mutations located in codons 609 (45 subjects), 611 (50), 618 (94), and 620 (151). MTC was present in 263 registrants, pheochromocytoma in 54, and hyperparathyroidism in 8 subjects. Of the patients with MTC, 53% were detected when asymptomatic, and among those with pheochromocytoma, 54%. Penetrance for MTC was 4% by age 10, 25% by 25, and 80% by 50. Codon-associated penetrance by age 50 ranged from 60% (codon 611) to 86% (620). More advanced stage and increasing risk of metastases correlated with mutation in codon position (609?620) near the juxtamembrane domain. Our data provide rigorous bases for timing of premorbid diagnosis and personalized treatment/prophylactic procedure decisions depending on specific RET exon 10 codons affected.