922 resultados para Medicines error


Relevância:

20.00% 20.00%

Publicador:

Resumo:

The focus of this paper is to address some classical results for a class of hypercomplex numbers. More specifically we present an extension of the Square of the Error Theorem and a Bessel inequality for octonions.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Corresponding to $C_{0}[n,n-r]$, a binary cyclic code generated by a primitive irreducible polynomial $p(X)\in \mathbb{F}_{2}[X]$ of degree $r=2b$, where $b\in \mathbb{Z}^{+}$, we can constitute a binary cyclic code $C[(n+1)^{3^{k}}-1,(n+1)^{3^{k}}-1-3^{k}r]$, which is generated by primitive irreducible generalized polynomial $p(X^{\frac{1}{3^{k}}})\in \mathbb{F}_{2}[X;\frac{1}{3^{k}}\mathbb{Z}_{0}]$ with degree $3^{k}r$, where $k\in \mathbb{Z}^{+}$. This new code $C$ improves the code rate and has error corrections capability higher than $C_{0}$. The purpose of this study is to establish a decoding procedure for $C_{0}$ by using $C$ in such a way that one can obtain an improved code rate and error-correcting capabilities for $C_{0}$.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Certain medicines are considered potentially inappropriate (PIM) for elderly people as they increase the risk of adverse drug events (ADE) and because safer alternative therapies are available on the market. In this context, in order to identify the instruments that assess the quality of medical prescriptions for elderly and to determine which drugs are considered PIM, a bibliographic survey was conducted in PUBMED, LILACS and PAHO databases, in February and March/2010. The search strategy included the use of health descriptors and a manual search in the references cited by selected papers. During the period of data collection, 15 instruments were identified. In 2012, with the publication of the update of Beers criteria, this instrument was included in the study. We identified 163 PIM of 25 therapeutic classes, of which 125 (76.7%) are marketed in Brazil. Of these, 31 (24.8%) are essential medicines (RENAME 2012), of which 13 have safer therapeutic equivalents and 19 (15.2%) are over-the-counter drugs. Data suggest the need for inclusion of safer alternatives for the elderly in the national list of essential medicines and the pharmaceutical care for early detection of ADE in this age group, in order to contribute to the safe use of medicines.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

You published recently (Nature 374, 587; 1995) a report headed "Error re-opens 'scientific' whaling debate". The error in question, however, relates to commercial whaling, not to scientific whaling. Although Norway cites science as a basis for the way in which it sets its own quota. scientific whaling means something quite different. namely killing whales for research purposes. Any member of the International Whaling Commission (IWC) has the right to conduct a research catch under the International Convention for the Regulation of Whaling. 1946. The IWC has reviewed new research or scientific whaling programs for Japan and Norway since the IWC moratorium on commercial whaling began in 1986. In every case, the IWC advised Japan and Norway to reconsider the lethal aspects of their research programs. Last year, however, Norway started a commercial hunt in combination with its scientific catch, despite the IWC moratorium.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

This work develops a computational approach for boundary and initial-value problems by using operational matrices, in order to run an evolutive process in a Hilbert space. Besides, upper bounds for errors in the solutions and in their derivatives can be estimated providing accuracy measures.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Estimates of evapotranspiration on a local scale is important information for agricultural and hydrological practices. However, equations to estimate potential evapotranspiration based only on temperature data, which are simple to use, are usually less trustworthy than the Food and Agriculture Organization (FAO)Penman-Monteith standard method. The present work describes two correction procedures for potential evapotranspiration estimates by temperature, making the results more reliable. Initially, the standard FAO-Penman-Monteith method was evaluated with a complete climatologic data set for the period between 2002 and 2006. Then temperature-based estimates by Camargo and Jensen-Haise methods have been adjusted by error autocorrelation evaluated in biweekly and monthly periods. In a second adjustment, simple linear regression was applied. The adjusted equations have been validated with climatic data available for the Year 2001. Both proposed methodologies showed good agreement with the standard method indicating that the methodology can be used for local potential evapotranspiration estimates.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The scope of this study was to estimate calibrated values for dietary data obtained by the Food Frequency Questionnaire for Adolescents (FFQA) and illustrate the effect of this approach on food consumption data. The adolescents were assessed on two occasions, with an average interval of twelve months. In 2004, 393 adolescents participated, and 289 were then reassessed in 2005. Dietary data obtained by the FFQA were calibrated using the regression coefficients estimated from the average of two 24-hour recalls (24HR) of the subsample. The calibrated values were similar to the the 24HR reference measurement in the subsample. In 2004 and 2005 a significant difference was observed between the average consumption levels of the FFQA before and after calibration for all nutrients. With the use of calibrated data the proportion of schoolchildren who had fiber intake below the recommended level increased. Therefore, it is seen that calibrated data can be used to obtain adjusted associations due to reclassification of subjects within the predetermined categories.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Since a genome is a discrete sequence, the elements of which belong to a set of four letters, the question as to whether or not there is an error-correcting code underlying DNA sequences is unavoidable. The most common approach to answering this question is to propose a methodology to verify the existence of such a code. However, none of the methodologies proposed so far, although quite clever, has achieved that goal. In a recent work, we showed that DNA sequences can be identified as codewords in a class of cyclic error-correcting codes known as Hamming codes. In this paper, we show that a complete intron-exon gene, and even a plasmid genome, can be identified as a Hamming code codeword as well. Although this does not constitute a definitive proof that there is an error-correcting code underlying DNA sequences, it is the first evidence in this direction.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Workplace accidents involving machines are relevant for their magnitude and their impacts on worker health. Despite consolidated critical statements, explanation centered on errors of operators remains predominant with industry professionals, hampering preventive measures and the improvement of production-system reliability. Several initiatives were adopted by enforcement agencies in partnership with universities to stimulate production and diffusion of analysis methodologies with a systemic approach. Starting from one accident case that occurred with a worker who operated a brake-clutch type mechanical press, the article explores cognitive aspects and the existence of traps in the operation of this machine. It deals with a large-sized press that, despite being endowed with a light curtain in areas of access to the pressing zone, did not meet legal requirements. The safety devices gave rise to an illusion of safety, permitting activation of the machine when a worker was still found within the operational zone. Preventive interventions must stimulate the tailoring of systems to the characteristics of workers, minimizing the creation of traps and encouraging safety policies and practices that replace judgments of behaviors that participate in accidents by analyses of reasons that lead workers to act in that manner.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

[ES] Este trabajo presenta algunas posibilidades de aprovechamiento de la opinión cualitativa de un auditor. Se desarrolla en torno a un caso ficticio que contiene las ideas básicas sobre la metodología expuesta.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The space environment has always been one of the most challenging for communications, both at physical and network layer. Concerning the latter, the most common challenges are the lack of continuous network connectivity, very long delays and relatively frequent losses. Because of these problems, the normal TCP/IP suite protocols are hardly applicable. Moreover, in space scenarios reliability is fundamental. In fact, it is usually not tolerable to lose important information or to receive it with a very large delay because of a challenging transmission channel. In terrestrial protocols, such as TCP, reliability is obtained by means of an ARQ (Automatic Retransmission reQuest) method, which, however, has not good performance when there are long delays on the transmission channel. At physical layer, Forward Error Correction Codes (FECs), based on the insertion of redundant information, are an alternative way to assure reliability. On binary channels, when single bits are flipped because of channel noise, redundancy bits can be exploited to recover the original information. In the presence of binary erasure channels, where bits are not flipped but lost, redundancy can still be used to recover the original information. FECs codes, designed for this purpose, are usually called Erasure Codes (ECs). It is worth noting that ECs, primarily studied for binary channels, can also be used at upper layers, i.e. applied on packets instead of bits, offering a very interesting alternative to the usual ARQ methods, especially in the presence of long delays. A protocol created to add reliability to DTN networks is the Licklider Transmission Protocol (LTP), created to obtain better performance on long delay links. The aim of this thesis is the application of ECs to LTP.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

In technical design processes in the automotive industry, digital prototypes rapidly gain importance, because they allow for a detection of design errors in early development stages. The technical design process includes the computation of swept volumes for maintainability analysis and clearance checks. The swept volume is very useful, for example, to identify problem areas where a safety distance might not be kept. With the explicit construction of the swept volume an engineer gets evidence on how the shape of components that come too close have to be modified.rnIn this thesis a concept for the approximation of the outer boundary of a swept volume is developed. For safety reasons, it is essential that the approximation is conservative, i.e., that the swept volume is completely enclosed by the approximation. On the other hand, one wishes to approximate the swept volume as precisely as possible. In this work, we will show, that the one-sided Hausdorff distance is the adequate measure for the error of the approximation, when the intended usage is clearance checks, continuous collision detection and maintainability analysis in CAD. We present two implementations that apply the concept and generate a manifold triangle mesh that approximates the outer boundary of a swept volume. Both algorithms are two-phased: a sweeping phase which generates a conservative voxelization of the swept volume, and the actual mesh generation which is based on restricted Delaunay refinement. This approach ensures a high precision of the approximation while respecting conservativeness.rnThe benchmarks for our test are amongst others real world scenarios that come from the automotive industry.rnFurther, we introduce a method to relate parts of an already computed swept volume boundary to those triangles of the generator, that come closest during the sweep. We use this to verify as well as to colorize meshes resulting from our implementations.