Differences in coronary risk factors, procedural characteristics, mortality and stent thrombosis between two all-comers percutaneous coronary intervention registries from Europe and Japan: a patient-level data analysis of the Bern-Rotterdam and j-Cypher registries

Aims: The reported rate of stent thrombosis (ST) after drug-eluting stent (DES) implantation varies among registries. To investigate differences in baseline characteristics and clinical outcome in European and Japanese all-comers registries, we performed a pooled analysis of patient-level data. Methods and results: The j-Cypher registry (JC) is a multicentre observational study conducted in Japan, including 12,824 patients undergoing SES implantation. From the Bern-Rotterdam registry (BR) enrolled at two academic hospitals in Switzerland and the Netherlands, 3,823 patients with SES were included in the current analysis. Patients in BR were younger, more frequently smokers and presented more frequently with ST-elevation myocardial infarction (MI). Conversely, JC patients more frequently had diabetes and hypertension. At five years, the definite ST rate was significantly lower in JC than BR (JC 1.6% vs. BR 3.3%, p<0.001), while the unadjusted mortality tended to be lower in BR than in JC (BR 13.2% vs. JC 14.4%, log-rank p=0.052). After adjustment, the j-Cypher registry was associated with a significantly lower risk of all-cause mortality (HR 0.56, 95% CI: 0.49-0.64) as well as definite stent thrombosis (HR 0.46, 95% CI: 0.35-0.61). Conclusions: The baseline characteristics of the two large registries were different. After statistical adjustment, JC was associated with lower mortality and ST.

Temporal evolution of strut light intensity after implantation of bioresorbable polymeric intracoronary scaffolds in the ABSORB cohort B trial-an application of a new quantitative method based on optical coherence tomography.

BACKGROUND Quantitative light intensity analysis of the strut core by optical coherence tomography (OCT) may enable assessment of changes in the light reflectivity of the bioresorbable polymeric scaffold from polymer to provisional matrix and connective tissues, with full disappearance and integration of the scaffold into the vessel wall. The aim of this report was to describe the methodology and to apply it to serial human OCT images post procedure and at 6, 12, 24 and 36 months in the ABSORB cohort B trial. METHODS AND RESULTS In serial frequency-domain OCT pullbacks, corresponding struts at different time points were identified by 3-dimensional foldout view. The peak and median values of light intensity were measured in the strut core by dedicated software. A total of 303 corresponding struts were serially analyzed at 3 time points. In the sequential analysis, peak light intensity increased gradually in the first 24 months after implantation and reached a plateau (relative difference with respect to baseline [%Dif]: 61.4% at 12 months, 115.0% at 24 months, 110.7% at 36 months), while the median intensity kept increasing at 36 months (%Dif: 14.3% at 12 months, 75.0% at 24 months, 93.1% at 36 months). CONCLUSIONS Quantitative light intensity analysis by OCT was capable of detecting subtle changes in the bioresorbable strut appearance over time, and could be used to monitor the bioresorption and integration process of polylactide struts.

De finantieele positie van den israel. godsdienstonderwijzer : Rede uitgespr. op de 8e algemeene vergadering van "Achawah" ... te Hilversum, op Dinsdag 14 Menachem 5656 (30 Juli 1901)

door A. van Creveld

Const Boeck, Nyeulijck wten alchemistichschen gront vergadert : tracterende van allen grondtlijcken ghebruyckinghe der consten ...

Gecolligiert ende eensdeels getranslateert door Symonem Andree

Gedenkschrift : uitgegeven ter gelegenheid van het 300-jarig bestaan der onderwijsinrichtingen Talmud Tora en Ets Hai͏̈m bij de Port. Israe͏̈l. Gemeente te Amsterdam : 5376 - 5676

M. C. Paraira en J. S. da Silva Rosa

De Hoogduitsche Joden in 's-Gravenhage van af hunne komst tot op heden

door D. S. van Zuiden

Verslag, uitgebragt in de een-en twintigste openbare vergadering van het Nederlandsch-Israelietisch armbestuur te Amsterdam ... den 17den September 1856

door S. E. Nykerk

De Synagoge der Portugeesch-Israelietische Gemeente te Amsterdam : 1675 - 1875 ; tot inl.: eenige geschiedkundige aanteekenigen betr. de vroegere bedehuizen dezer gemeente ; een gedenkschrift ter gelegenheid van haar tweede-eeuwfeest

door D. H. de Castro

Geschiedkundig overzicht over een kwarteeuw, uitgebracht in de algemeene vergadering tot herdenking van het 25-jarig bestaan der stichting, op zondag 21 Augustus 1898

Israe͏̈litisch Ziekenhuis te 's-Gravenhage, opgericht in 1873 / [B.Blok]

Redevoering gehouden ter inwijding van het Nederlandsch Israe͏̈litsch Oude Mannen- en Vrouwen- en Ziekenhuis, te Amsterdam

door S. E. Nykerk

Verslag, uitgebracht in de negentiende openbare vergadering van het Nederlandsch-Israelietisch Armbestur te Amsterdam, ...

door S. E. Nykerk