973 resultados para Exhaustive physical exercise


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Objetivo: evaluar el efecto del té verde o sus sucedáneos en el estado nutricional de los sujetos que realizan ejercicio físico. Metodología: las palabras clave son: “green tea” AND “exercise”, en cuatro bases de datos documentales: Pubmed, EBSCOHOST, OvidSP y Proquest. Criterios de inclusión (enero de 2010 y diciembre de 2014): edad adulta de la muestra (18-65 años, OMS); consumo de una cantidad cuantificada de té verde o sucedáneos, junto con la realización de ejercicio físico medible en intensidad. Resultados: de 260 artículos, se incluyeron el 5%. En el 69% se trata de estudios con un entrenamiento diseñado, y en el 92% se ha incluido un test de ejercicio para valorar parámetros. El 77% oscilan entre 20-40 años; las muestras varían entre 9 y 36 individuos. El 69% son de larga duración. El GTE ha sido el sucedáneo más utilizado (38%). El 92% de los ensayos han obtenido algún tipo de mejora (en el 92% fue significativa). Conclusiones: se recomienda aumentar las investigaciones sobre la clasificación de los ejercicios. Las mejoras significativas en el estado nutricional de los sujetos por la ingesta del té verde o sucedáneos son: IMC, peso, IGC, MM, INM, OM y MR. El GTE ha sido el que mayores resultados satisfactorios ha proporcionado. No existe homogeneidad en los resultados significativos. Se necesitan realizar nuevos ensayos clínicos. Las diferencias entre los ensayos clínicos revisados reflejan que las mejoras encontradas en el estado nutricional de los sujetos que realizan actividad física deben ser avaladas con nuevas investigaciones. Esto ayudará a crear evidencia en este tipo de aspectos.

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Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2014

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O objetivo principal da pesquisa encetada foi o de ressaltar a importância do discurso de Ellen White, uma importante líder religiosa do século XIX, nos Estados Unidos da América, para a formação de um estilo e prática de vida, que ainda hoje caracteriza os adventistas do sétimo dia no que se refere a saúde. Outro, não menos importante objetivo, foi o de comparar os principais conceitos de Ellen White sobre saúde e estilo de vida com algumas preocupações científicas e acadêmicas contemporâneas. Para isso, este trabalho mostra como a lista de oito remédios naturais propostos por White sumarizam o ideal de uma vida saudável ainda praticada por milhões de adventistas, 100 anos após a morte de sua Profetiza: ar puro, água, alimentação adequada, luz solar, exercícios físicos, repouso, abstinência, e confiança em Deus. Os conselhos de White foram contrastados com várias práticas culturais que relacionam religião e saúde, levando-nos à conclusão que a cultura adventista tem se mostrado como a mais adequada na salvaguarda da saúde. Isto porque White apresentou uma síntese de elementos da cultura judaica, cristã e ocidental. Nesse sentido, as suas orientações garantem-lhe um lugar privilegiado no movimento de reforma da saúde nos Estados Unidos que ocorreu naquele País na segunda metade do século XIX. Muitos de seus conselhos estão sendo atualmente colocados em prática por todos aqueles que se preocupam com a saúde, longevidade, e a adequação do estilo de vida com as regras inspiradas na natureza e numa espiritualidade sadia.

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The development of adult-onset diseases such as type II diabetes, obesity and cardiovascular disease is traditionally attributed to adult lifestyle characteristics such as a lack of physical exercise, poor diet and smoking. However, evidence from both human and animal model studies has demonstrated that environmental factors such as an imbalance or reduction in maternal nutrition during gestation can have adverse effects on offspring metabolism and cardiovascular health. The severity and nature of the phenotypic changes induced in offspring is influenced by the period of gestation manipulated. In particular, the mammalian preimplantation embryo in different animal models displays particular sensitivity to environmental factors, either in vivo (maternal diet) or in vitro (embryo culture) that is associated with the onset of cardiovascular dysfunction in adult life. The detailed mechanisms by which environmental conditions can alter postnatal cardiovascular physiology are poorly understood. However, various factors including endothelial function, vascular responsiveness, the renin-angiotensin system, kidney structure and early postnatal growth dynamics have all been recognize as potential contributors. Here, we review the relationship between preimplantation embryo environment and postnatal cardiovascular disease risk, and consider biochemical, molecular, genetic and physiological pathways implicated in this association. © 2009 The Authors Journal compilation © 2009 Anatomical Society of Great Britain and Ireland.

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There is a growing societal need to address the increasing prevalence of behavioral health issues, such as obesity, alcohol or drug use, and general lack of treatment adherence for a variety of health problems. The statistics, worldwide and in the USA, are daunting. Excessive alcohol use is the third leading preventable cause of death in the United States (with 79,000 deaths annually), and is responsible for a wide range of health and social problems. On the positive side though, these behavioral health issues (and associated possible diseases) can often be prevented with relatively simple lifestyle changes, such as losing weight with a diet and/or physical exercise, or learning how to reduce alcohol consumption. Medicine has therefore started to move toward finding ways of preventively promoting wellness, rather than solely treating already established illness. Evidence-based patient-centered Brief Motivational Interviewing (BMI) interven- tions have been found particularly effective in helping people find intrinsic motivation to change problem behaviors after short counseling sessions, and to maintain healthy lifestyles over the long-term. Lack of locally available personnel well-trained in BMI, however, often limits access to successful interventions for people in need. To fill this accessibility gap, Computer-Based Interventions (CBIs) have started to emerge. Success of the CBIs, however, critically relies on insuring engagement and retention of CBI users so that they remain motivated to use these systems and come back to use them over the long term as necessary. Because of their text-only interfaces, current CBIs can therefore only express limited empathy and rapport, which are the most important factors of health interventions. Fortunately, in the last decade, computer science research has progressed in the design of simulated human characters with anthropomorphic communicative abilities. Virtual characters interact using humans’ innate communication modalities, such as facial expressions, body language, speech, and natural language understanding. By advancing research in Artificial Intelligence (AI), we can improve the ability of artificial agents to help us solve CBI problems. To facilitate successful communication and social interaction between artificial agents and human partners, it is essential that aspects of human social behavior, especially empathy and rapport, be considered when designing human-computer interfaces. Hence, the goal of the present dissertation is to provide a computational model of rapport to enhance an artificial agent’s social behavior, and to provide an experimental tool for the psychological theories shaping the model. Parts of this thesis were already published in [LYL+12, AYL12, AL13, ALYR13, LAYR13, YALR13, ALY14].

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The Acquired Immune Deficiency Syndrome (AIDS), considered today one chronic nature of the disease due to the advent of antiretroviral therapy (TARV), brings to individuals living with this disease, difficulties related to social interaction and adaptation to new physical condition and the routines imposed by the treatment. This reality has a strong impact on the lives of these people in order of overcoming them use coping strategies, Coping. In this context, the aim of this study was to characterize the epidemiological, clinical and life habits of people living with AIDS and analyze the coping strategies used with the situation of the disease, according to sociodemographic, clinical and life habits. This is a cross-sectional study with a quantitative approach. The sample consisted of 331 people registered at the clinic of the Hospital Giselda Trigueiro (HGT), located in Natal / RN, who had scheduling for outpatient medical consultation from January to August 2014. The study was approved by the Ethics Committee the Federal University of Rio Grande do Norte with the Presentation of Certificate for Ethics Assessment (CAAE), paragraph 16578613.0.0000.5537. The data of social characterization showed predominance of men (52%), young people (42%) coming from the capital (58%), mulatto (53%), single (56%), heterosexual (79%), poor (68 %). With regard to clinical aspects it has been found that most held the first HIV testing for less than five years (60%) had signs and symptoms of AIDS before the examination (90%) were hospitalized (90%) started ART for less than five years (60%) believe they have good knowledge of the disease (75%) and believe that their health has improved (92%). For lifestyle, it became clear that most do not consume alcohol (71%), do not smoke (88%) and do not use illicit drugs (92%) and never used condoms before diagnosis (62%) and only 192 (58%) use the currently codon. With regard to the reference was higher coping focused modes of emotion, although the problem solving has been the second most common. The mean scores of women, workers, religious and never abandoned the treatment were higher for all factors. Having a partner, living with family members and support in the treatment had higher average scores for various factors, coinciding in the confrontation, withdrawal and social support. As for the leisure and physical exercise also dominated the modes focused on emotion as was seen in the correlation between the time of treatment, education and family income and IEEFL factors, although with low intensity. The profile of the study population confers with national characteristics, suggesting feminization, internalization, pauperization, heterosexual, increased CD4 cell count and viral load reduction during treatment and maintaining healthy lifestyle habits. Coping strategies used were more focused on emotion. In this context, it is understood that the identification of these strategies can facilitate care planning, encouraging such persons to adapt to stressors with the situation of the disease

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Introduction: Several modifications are identified as aging, causing more or less limitation imposed by over the years. Among these, one can highlight the different degrees of cognitive decline, particularly memory that can involve the daily activities and the subject functionality. Studies have shown an association between levels of serum cortisol and stress imposed by the exercise on this. However, there are few studies that references the performance on cognitive aspects of declarative memory and cortisol on the exercise in the water with automatic and práxicos movements and moderate. Objective: Check the effect based on the acute physical exercise and práxicos automatic movements on the performance of visual declarative memory and in serum cortisol in subjects aged between 51 and 74 years. Materials and Methods: It builds a survey characterized as cross with a first sample of 32 physically active subjects aged between 51 and 74 years, divided into two exercise groups (March of Automatic Group - MAG and the March of Praxis Group - MPG). We used a probabilistic and random sampling for sample selection. Used the MMSE (Mini Mental State Examination) to check the general cognitive status, visual acuity test - optotypes chart "E" Rasquin and was even used the declarative visual memory test proposed by Nitrini and collaborators (1994), applying before motor stimulation and immediately after, and the day of blood collection with 2 ml for analysis of cortisol hormone. The normality and homogeneity were verified from the Shapiro-Wilk and Levene tests. Thus we adopted a descriptive statistics to characterize the sample. The Split-Plot ANOVA was used along with the paired t-test to verify the identified differences. We adopted a significance level of p <0.05. Results: It was observed that the groups (MAG and MPG) and the anthropometric variables, perceived exertion, education, cognitive assessment and visual acuity showed no significant differences (p > 0.05), showing that the groups are homogeneous, with variables and similar means. After the stimulation session, lasting 30 min, it was observed that the amount of hits for Δ of declarative memory questionnaire visual images increased, presenting significant for both groups (MAG, p < 0.001; MPG, p = 0.042). The same was observed for cortisol concentration with a reduction in the levels immediately after the stimulus (MAG and MPG, p < 0.001). Conclusion: The results showed that the exercises proposed in its acute effect provide significantly memories of gains and also showed a reduction in cortisol levels.

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The increased incidence along to new therapies for the treatment of HIV/AIDS bring way up exercise as a treatment option, as this promotes relevant changes in the general functioning of the body. The objective of this study was to evaluate in different periods the influence of exercise on quality of life and quality of sleep people living with HIV/AIDS, Natal/RN. The sample consisted of 17 people living with HIV/AIDS participating in physical exercise program, along accompanied by 25 months during the period January 2013 to April 2015. We evaluated through specific instruments quality of life, sleep quality and immunological parameters, which were evaluated before starting the exercise program and reassessed during periods of 2-4 months (short), 5-17 months (average period or intermediate) and finally to 19-25 months (long period). The results showed significant differences in five of the nine areas of quality life, pointing positive behaviors, specifically in the areas overall function, life satisfaction, health concerns, concerns about the medication and acceptance to HIV. We conclude that physical exercise promoted benefits both in short and long term, especially for the areas of quality of life of people living with HIV/AIDS and also demonstrated positive behavior changes and to aspects of sleep quality.

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En plus de contribuer à améliorer la santé de façon générale, l’activité physique chronique pourrait modérer le déclin cognitif associé au vieillissement normal et pathologique (Colcombe et Kramer, 2003; Heyn et al., 2004). Plus précisément, la pratique à long terme d’activités cardiovasculaires aurait des effets positifs sur la cognition des ainés et plus particulièrement sur le contrôle attentionnel, un aspect précocement touché au cours du vieillissement (Raz, 2000; Bherer et al., 2008). Toutefois, les mécanismes par lesquels l’exercice physique aigu améliore la cognition demeurent limités. Malgré ses nombreuses implications théoriques et pratiques, la réponse aiguë de l’oxygénation cérébrale à l’exercice physique et sa relation avec la cognition sont trop peu étudiées. Cette thèse se consacre à cette question. Des études récentes en neuro-imagerie chez les jeunes adultes démontrent que la relation entre l’oxygénation cérébrale et l’intensité de l’exercice suit la forme d’un U inversé. Il existe un seuil au-delà duquel l’oxygénation cérébrale diminue avec l’augmentation de l’intensité de l’exercice. Supposant que les performances cognitives dépendent de la disponibilité de l’oxygène cérébral, cette relation en U inversé devrait affecter les performances cognitives. Avant de préciser le rôle exact de l’oxygénation cérébrale sur les fonctions cognitives, nous avons d’abord examiné le temps nécessaire pour que l’oxygénation cérébrale atteigne un état stable et la durée pendant laquelle cette période stable peut être maintenue lors de paliers de sept minutes à une puissance sous-maximale (40%, 60% et 85% de la puissance aérobie maximale). Nos résultats soulignent l’existence d’une relation inverse entre la durée de l’état stable et l’intensité de l’exercice. Suite à cette vérification méthodologique, la prochaine étape a été de tester la possible relation entre l’oxygénation cérébrale, l’intensité de l’exercice et les performances cognitives, au cours du processus de vieillissement. Les résultats de ces études démontrent que la chute de l’oxygénation cérébrale observée lors des exercices de haute intensité est associée avec une diminution des performances cognitives. Les résultats de cette thèse corrigent l’écart existant dans la documentation entre l’exercice, les fonctions cognitives et les mécanismes neurophysiologiques.

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Syfte Syftet var att undersöka vad aktiva-motionärer anser om vardags-motionärer avseende livsstil, karaktärsdrag och hälsostatus. Metod För att inkludera vardags-motionärer på motionsanläggningar där motionärer finns bör man lösa upp barriärer till motion. Det kan därför vara av nytta att ta reda på om och i så fall vad aktiva-motionärer anser om vardags-motionärer. Detta för att kunna veta om förändringen ska ske hos aktiva-motionärer eller vardags-motionärer för att möjliggöra inkludering av vardagsmotionärer på motionsanläggningar där aktiva-motionärer finns. Detta genomfördes med en kvalitativt inriktad undersökning genom en intervjustudie i form av semistrukturerade intervjuer. Resultat Respondenterna anger att hälsa är en upplevd balans såväl psykiskt som fysiskt. I motsats till detta innebär ohälsa obalans. Konsekvenserna av denna obalans nämnde respondenterna som trötthet, sämre koncentration, övervikt, lättare att drabbas av sjukdomar samt försämrad livskvalité. Det respondenterna nämnde om en vardags-motionär är att denna individ sällan gör mer än vad det behöver i vardagen, är ohälsosamma, innehar obalans och kan drabbas av konsekvenserna som nämns ovan. Slutsats Undersökningen visar att det finns åsikter hos aktiva-motionärer om vardags-motionärer. Dock uttalar sig aktiva-motionärer ogärna om hur vardags-motionärer är som personer, men beskriver enklare deras leverne. Det undersökningen därmed kan konstatera är att andras åsikter är en befogad barriär till varför motion inte bedrivs. Om denna barriär är något som syns utåt på anläggningarna är dock svårt att säga.

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Suite à l’exposition à des facteurs de risque incluant la malnutrition, la dyslipidémie, la sédentarité et les désordres métaboliques, les maladies cardiovasculaires (MCV) sont caractérisées par un état pro-oxydant et pro-inflammatoire, et une dérégulation de l’expression de divers facteurs responsables de l’homéostasie de l’environnement rédox et inflammatoire. L’implication d’enzymes antioxydantes telles que les superoxyde dismutases (SOD) et les glutathion peroxydases (Gpx), ainsi que la contribution de médiateurs pro-inflammatoires tels que l’angiopoietin-like 2 (Angptl2) ont été rapportées dans le cadre des MCV. Toutefois, les mécanismes moléculaires sensibles aux facteurs de risque et menant au développement des MCV sont peu connus. L’épigénétique est un mécanisme de régulation de l’expression génique sensible aux stimuli extracellulaires et pourrait donc contribuer au développement des MCV. La méthylation de l’ADN est un des mécanismes épigénétiques pouvant varier tant de manière gène-spécifique qu’à l’échelle génomique, et la conséquence de tels changements sur l’expression des gènes ciblés dépend du site de méthylation. Puisqu’il a été démontré que des variations au niveau de la méthylation de l’ADN peuvent être associées à divers contextes pathologiques incluant les MCV, le but de nos travaux était d’étudier le lien entre la méthylation de gènes antioxydants et pro-inflammatoires avec leurs répercussions fonctionnelles biologiques en présence de facteurs de risques associés aux MCV, tels que le vieillissement, la dyslipidémie et la sédentarité. Dans la première étude, nous avons observé que dans l’artère fémorale de souris vieillissantes, la méthylation au niveau du promoteur du gène Sod2, codant pour l’enzyme antioxydante superoxyde dismutase de type 2 (SOD2 ou MnSOD), diminue avec l’âge. Ceci serait associé à l’induction de l’expression de MnSOD, renforçant ainsi la défense antioxydante endogène. Le vieillissement étant associé à une accumulation de la production de radicaux libres, nous avons étudié la vasodilatation dépendante de l’endothélium qui est sensible au stress oxydant. Nous avons observé que la capacité vasodilatatrice globale a été maintenue chez les souris âgées, aux dépens d’une diminution des facteurs hyperpolarisants dérivés de l’endothélium (EDHF) et d’une contribution accentuée de la voie du monoxyde d’azote (NO). Nous avons ensuite utilisé deux approches visant à réduire les niveaux de stress oxydant in vivo, soit la supplémentation avec un antioxydant, la catéchine, et l’exposition chronique à de l’exercice physique volontaire. Ces interventions ont permis de prévenir à la fois les changements au niveau de la fonction endothéliale et de l’hypométhylation de Sod2. Cette première étude démontre donc la sensibilité de la méthylation de l’ADN à l’environnement rédox. Dans la deuxième étude, nous avons démontré une régulation de l’expression de l’enzyme antioxydante glutathion peroxydase 1 (Gpx1) en lien avec la méthylation de son gène codant, Gpx1, dans un contexte de dyslipidémie sévère. Nos résultats démontrent que dans le muscle squelettique de souris transgéniques sévèrement dyslipidémiques (LDLr-/-; hApoB+/+), Gpx1 est hyperméthylé, ce qui diminue l’expression de Gpx1 et affaiblit la défense antioxydante endogène. Chez ces souris, l’exercice physique chronique a permis d’augmenter l’expression de Gpx1 en lien avec une hypométhylation transitoire de son gène. Cette étude démontre que le stress oxydant associé à la dyslipidémie sévère altère les mécanismes de défense antioxydante, en partie via un mécanisme épigénétique. De plus, on observe également que l’exercice physique permet de renverser ces effets et peut induire des changements épigénétiques, mais de manière transitoire. La troisième étude avait pour but d’étudier la régulation de l’Angptl2, une protéine circulante pro-inflammatoire, dans le contexte des MCV. Nous avons observé que chez des patients coronariens, la concentration circulante d’Angptl2 est significativement plus élevée que chez des sujets sains et ce, en lien avec une hypométhylation de son gène, ANGPTL2, mesurée dans les leucocytes circulants. Nous sommes les premiers à démontrer qu’en réponse à l’environnement pro-inflammatoire associé à une MCV, l’expression de l’Angptl2 est stimulée par un mécanisme épigénétique. Nos études ont permis d’identifier des nouvelles régions régulatrices différentiellement méthylées situées dans les gènes impliqués dans la défense antioxydante, soit Sod2 en lien avec le vieillissement et Gpx1 en lien avec la dyslipidémie et l’exercice. Nous avons également démontré un mécanisme de régulation de l’Angptl2 dépendant de la méthylation d’ANGPTL2 et ce, pour la première fois dans un contexte de MCV. Ces observations illustrent la nature dynamique de la régulation épigénétique par la méthylation de l’ADN en réponse aux stimuli environnementaux. Nos études contribuent ainsi à la compréhension et l’identification de mécanismes moléculaires impliqués dans le développement du phénotype pathologique suite à l’exposition aux facteurs de risque, ce qui ouvre la voie à de nouvelles approches thérapeutiques.

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Esta investigación pretende determinar los principales parámetros cardio-respiratorios de las mujeres con fibromialgia y su clasificación en función del nivel de afectación para una posterior prescripción de actividad física.

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Physical exercise programmes are routinely prescribed in clinical practice to treat impairments, improve activity and participation in daily life because of their known physiological, health and psychological benefits (RCP, 2009). Progressive resistance exercise is a type of exercise prescribed specifically to improve skeletal muscle strength (Latham et al., 2004). The effectiveness of progressive resistance exercise varies considerably between studies and populations. This thesis focuses on how training parameters influence the delivery of progressive resistance exercise. In order to appropriately evaluate the influence of training parameters, this thesis argues the need to record training performance and the total work completed by participants as prescribed by training protocols. In the first study, participants were taken through a series of protocols differentiated by the intensity and volume of training. Training intensity was defined as a proportion of the mean peak torque achieved during maximal voluntary contractions and was set at 80% and 40% respectively of the MVC mean peak torque. Training volume was defined as the total external work achieved over the training period. Measures of training performance were developed to accurately report the intensity, repetitions and work completed during the training period. A second study evaluated training performance of the training protocols over repeated sessions. These protocols were then applied to 3 stroke survivors. Study 1 found sedentary participants could achieve a differentiated training intensity. Participants completing the high and low intensity protocols trained at 80% and 40% respectively of the MVC mean peak torque. The total work achieved in the high intensity low repetition protocol was lower than the total work achieved in the low intensity high repetition protocol. With repeated practice, study 2 found participants were able to improve in their ability to perform manoeuvres as shown by a reduction in the variation of the mean training intensity achieving total work as specified by the protocol to a lower margin of error. When these protocols were applied to 3 stroke survivors, they were able to achieve the specified training intensity but they were not able to achieve the total work as expected for the protocol. This is likely to be due to an inability in achieving a consistent force throughout the contraction. These results demonstrate evaluation of training characteristics and support the need to record and report training performance characteristics during progressive resistance exercise, including the total work achieved, in order to elucidate the influence of training parameters on progressive resistance exercise. The lack of accurate training performance may partly explain the inconsistencies between studies on optimal training parameters for progressive resistance exercise.

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Um ritmo circadiano normal, hábitos alimentares saudáveis, prática de exercício físico regular e uma boa higiene de sono constituem fatores imprescindíveis para o bom funcionamento do organismo e para a prevenção de diversas doenças. Os universitários constituem uma população bastante vulnerável a ritmos circadianos anormais, hábitos alimentares pouco saudáveis, sedentarismo e problemas de sono, provenientes das alterações no seu estilo de vida bem como alterações a nível comportamental. O objetivo deste estudo é identificar o cronótipo (matutino, intermédio ou vespertino), os hábitos alimentares e de sono dos alunos universitários. Neste sentido utilizou-se uma amostra de 302 estudantes da Universidade Fernando Pessoa, no qual 238 são do sexo feminino e os restantes 64 são do sexo masculino. Com a finalidade da recolha de dados foi elaborado um questionário através do Formulários do Google. Para avaliar o tipo de cronótipo dos universitários aplicou-se o Morningness-Eveningness Questionnaire (MEQ) e os hábitos de sono foram avaliados a partir do Pittsburgh Sleep Quality Index (PSQI) e da Epworth Sleepiness Scale (ESS). Para avaliar os hábitos alimentares dos participantes formulou-se um conjunto de questões tendo em conta este objetivo. Estes dados foram recolhidos on-line, tendo sido enviado o questionário a todos os alunos da Universidade Fernando Pessoa através do respetivo correio eletrónico institucional. No final desta investigação, foi possível concluir que a maioria dos alunos universitários apresenta um cronótipo intermédio (50 pontos ± 9,43), hábitos alimentares saudáveis e equilibrados e apresenta ainda uma má qualidade de sono (8 pontos ± 2,86) e padrões de sono irregulares, no entanto, não exibem sonolência diurna excessiva (8 pontos ± 3,96).