854 resultados para 2D Technologies


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Background: Sex steroid exposure during early human development may influence disease susceptibility. Digit ratio (2D:4D) is a putative marker for prenatal hormone exposure and sensitivity, as well as the action of genes closely related to carcinogenesis. Digit ratio could act as a possible marker for cancer predisposition. Aims: The aim of this study is to investigate the possible correlations between right hand, left hand and right minus left (R. - L) 2D:4D and gastric cancer (GCA) in men and women and assess the correlations with tumor staging and histological diagnosis. Methods: Digital images of the right and left hand palms of patients diagnosed with GCA (n = 57, 42 males, 15 females) and age and sex-matched controls (n = 59, 41 males, 18 females) were obtained. Means for 2D:4D were compared. Data were analyzed by repeated-measures one-way ANOVA and Student's t-test for finger measurements and group comparisons and Pearson's and Spearman's tests for correlations with tumor staging (α = 0.05). Results: GCA group presented significantly higher left 2D:4D, but significantly lower R. - L in comparison to healthy controls, particularly so for males. Digit ratio did not correlate to clinical staging or TNM staging. However, low R. - L was significantly related to adenocarcinomas. Conclusions: Early developmental conditions, including prenatal testosterone seem to play a role on the malignant transformation of gastric lesions. The 2D:4D pattern found for gastric cancer parallels that earlier described for breast cancer. The findings suggest that 2D:4D could add to the list of etiological factors and be a putative marker for the screening of patients' susceptibility to develop gastric cancer. © 2012 Elsevier Ltd.

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Contiene asistencia y organizacion de los trabajos, conclusiones y recomendaciones del Seminario que tuvo por objeto analizar el estado de avance en cuanto a inventarios y evaluacion de recuperacion de andenes; identificar dificultades encontradas y estrechar vinculos institucionales y de cooperacion entre organismos gubernamentales y no gubernamentales, la universidad peruana y los organismos internacionales de cooperacion para el desarrollo.

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Contiene asistencia y organización de los trabajos, conclusiones y recomendaciones del Seminario que tuvo por objeto analizar el estado de avance en cuanto a inventarios y evaluación de recuperación de andenes; identificar dificultades encontradas y estrechar vínculos institucionales y de cooperación entre organismos gubernamentales y no gubernamentales, la universidad peruana y los organismos internacionales de cooperación para el desarrollo.

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Analiza las necesidades de la colaboracion regional en los procesos de integracion de las nuevas tecnologias a las estrategias de desarrollo nacional y regional en el Caribe.

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Includes bibliography