Boris Vian dans ses poèmes

El artículo se propone mostrar cómo el estudio de los poemas y canciones de Boris Vian sólo cobra sentido mediante un análisis de conjunto. Tras la aparente dispersión de temas y estilos, bajo la apariencia superficial, cómica y en ocasiones incluso grotesca y banal de sus poemas y canciones, se oculta una unidad y una coherencia profundas y minuciosamente calculadas. Para expresarla Vian huye de las limitaciones de la lógica heredada de Aristóteles y opta por utilizar la técnica del collage, yuxtaponiendo una pluralidad de situaciones y acciones en las que lo real se entremezcla con lo imaginario, cuyo resultado final es la representación de una realidad única, indivisible y a la vez relativa y singular en función de cada individuo, en la que los aparentes antagonismos se revelan como elementos complementarios en el proceso de individualización y conocimiento del «yo» interior.

Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells.

Cancer stem cells are cancer cells characterized by stem cell properties and represent a small population of tumor cells that drives tumor development, progression, metastasis and drug resistance. To date, the molecular mechanisms that generate and regulate cancer stem cells are not well defined. BORIS (Brother of Regulator of Imprinted Sites) or CTCFL (CTCF-like) is a DNA-binding protein that is expressed in normal tissues only in germ cells and is re-activated in tumors. Recent evidences have highlighted the correlation of BORIS/CTCFL expression with poor overall survival of different cancer patients. We have previously shown an association of BORIS-expressing cells with stemness gene expression in embryonic cancer cells. Here, we studied the role of BORIS in epithelial tumor cells. Using BORIS-molecular beacon that was already validated, we were able to show the presence of BORIS mRNA in cancer stem cell-enriched populations (side population and spheres) of cervical, colon and breast tumor cells. BORIS silencing studies showed a decrease of sphere formation capacity in breast and colon tumor cells. Importantly, BORIS-silencing led to down-regulation of hTERT, stem cell (NANOG, OCT4, SOX2 and BMI1) and cancer stem cell markers (ABCG2, CD44 and ALDH1) genes. Conversely, BORIS-induction led to up-regulation of the same genes. These phenotypes were observed in cervical, colon and invasive breast tumor cells. However, a completely different behavior was observed in the non-invasive breast tumor cells (MCF7). Indeed, these cells acquired an epithelial mesenchymal transition phenotype after BORIS silencing. Our results demonstrate that BORIS is associated with cancer stem cell-enriched populations of several epithelial tumor cells and the different phenotypes depend on the origin of tumor cells.

[Borisin kuolema oopperasta Boris Godunov]

Äänitetty radiosta.

BORIS – It’s never too late to start a repository

Presentation at Open Repositories 2014, Helsinki, Finland, June 9-13, 2014

Tabvla Rvssiae ex autographo, quod delineandum curavit Foedor filius tzaris Boris desumta; et ad fluvios Dwinam, Zuchanam, aliaque loca, quantum ex tabulis et notitiis ad nos delatis fieri potuit, amplificata: ac magno domino, tzari , et magno duci Michäeli Foedorowits omnium Russorum, autcratori Wolodimeriae, Moscoviae et Novogardia. Tzari Cazaniae, tzari Astracaniae, tzari Siberiae, domino Plescoviae magno duci Smolenscoviae, Otweriae, Iugoriae, Permiae, Wiatkiae, Bulgariae etc: domino regionum Iveriae Kartalinie et Groesiniae tzari etc: dedicata ab Hesselo Gerardo M.DC.XIIII.

[N. 1:9000000].

Tabula Russiae ex autographo, quod delineandum curavit Foedor filius tzaris Boris desumta et ad fluvios Dwinam Zuchanaw aliaque loca quandum ex tabulis et notitÿs ad nos delatis fieri potuit amplificaca alias dicta Moscovia.

[N. 1:10000000].

De anima in genere (1652)

Invokaatio: Sun Theo.

Le roi Boris de Bulgarie : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 59807

Epistolario. 4, 1719-1732 e indici generali / Jean Le Clerc ; a cura di Maria Grazia e Mario Sina

Collection : Le Corrispondenze letterarie, scientifiche ed erudite dal Rinascimento all'età moderna ; 1, 2, 5,6

Arrest du conseil d'Estat du Roy, qui supprime, en faveur du public, les droits des offices de controlleurs des greffiers gardes-minutes des chancelleries . Et ordonne que le remboursement en sera fait sur le caissier de la Compagnie des Indes. Du 19 decembre 1719. Extrait des registres du Conseil d'Estat.

[Acte. 1719-12-19. Paris]

Arrêt du conseil d'état qui ordonne que l'emploi des gages des offices créés dans les cours supérieures, sera fait dans les états qui seront arrêtés pour l'année 1720 et les suivantes sur le même pied sur lequel ils ont été employés dans ceux de l'année 1719

[Acte. 1721-05-06. Paris]