物乞いするのは貧しいからか

大学3年の夏休みに物乞いをした。岩手の地方都市に帰省しており、そこから電車で1時間ほどの盛岡に用事があった。用事を済ませたら古本屋があり、そこで鳥居泰彦著『経済発展論』を見つけた。以前から欲しかった本なので、それを買うと帰りの電車賃しか残らないことを知りつつ、買った。盛岡駅に着いたら、実は所持金が電車賃に数十円足りないことがわかり愕然とした。（以下略）

能力は有限、知識は無限

1993年にアメリカのロチェスター大学でSergio Rebelo準教授（当時）の経済成長論を履修した。ある授業でRebelo教授に「しばしば人的資本と技術は混同されがちだけれども、両者は財の性質上、大きく異なっている。技術、中でも他人に簡単に伝達できるように文書や設計図に記されている知識は公共財的性質を持っているが、人的資本はむしろ通常の財に似ている。知識は他人に簡単に漏洩し盗用されやすいが、人的資本はその所有者が専有可能である。その上、人的資本はその所有者が死んでしまえば消失するが、知識は記録として残る。この意味で、人的資本蓄積は有限だが、知識の蓄積は無限に可能である」と教わった。自分はそれまで、新古典派成長理論で仮定される「労働に体化された技術進歩」ばかり勉強していたので、技術と人的資本を同一視していた。それだけにこの説明は非常に新鮮であった。（以下略）

国際協力の罪と罰：買わない日本人

会社でも学校でも結果を問われる時代になった。会社では賃金のうち年功序列的部分が縮小され、業績給部分の割合が増えている。大学生の成績も、以前より明確な基準を用いて、学生の間に明白な差をつけて採点することが要求されるようになってきている。これまでは努力を含めて「何をどれだけ投入したか」が基準として重視されていたのに対して、最近は「何をどれだけ実現したか」という成果が重視されるようになってきている。（以下略）

SARSとマラリア：感染症と経済学

近年、感染症が注目を集めている。一昨年の冬は東アジアでSARS（重症急性呼吸器症候群）が流行した。SARSは新型肺炎とも呼ばれ、中国および香港を中心に感染が広がった。日本にはSARSに感染した台湾人男性が数日間滞在したことから、この男性の訪問先が善後策に追われたことが記憶に新しい。この冬も再流行が懸念されたのであるが、対策が進んだためか、感染は中国で4人が確認されるに止まっているようである。（以下略）

Middle Miocene isotope stratigraphy and paleoceanographic evolution of the northwest and southwest Australian margins (Wombat Plateau and Great Australian Bight)

The benthic stable isotope record from ODP Site 761 (Wombat Plateau, NW Australia, 2179.3 m water depth) documents complete recovery of the middle Miocene delta13C excursion corresponding to the climatic optimum and subsequent expansion of the East Antarctic Ice Sheet. The six main delta13C maxima of the "Monterey Excursion" between 16.4 and 13.6 Ma and the characteristic stepped increase in delta18O between 14.5 and 13.9 Ma are clearly identified. The sedimentary record of the shallower ODP Sites 1126 and 1134 [Great Australian Bight (GAB), SWAustralia, 783.8 and 701 m water depth, respectively] is truncated by several unconformities. However, a composite benthic stable isotope curve for these sites provides a first middle Miocene bathyal record for southwest Australia. The delta18O and delta13C curves for Sites 1126 and 1134 indicate a cooler, better-ventilated water mass at ~700 m water depth in the Great Australian Bight since approximately 16 Ma. This cooler and younger water mass probably originated from a close southern source. Cooling of the bottom water at ~16 Ma started much earlier than at other sites of equivalent paleodepths in the central and western parts of the Indian Ocean. At Site 761, the delta18O curve shows an excellent match with the global sea level curve between ~11.5 and 15.1 Ma, and thus closely reflects changes in global ice volume. Prior to 15.1 Ma, the mismatch between the delta18O curve and the sea level curve indicates that delta18O fluctuations are mainly due to changes in bottom water temperature.

Use of oesophagogastroscopy to assess the response of oesophageal carcinoma to neoadjuvant therapy

Background: Approximately 25 per cent of patients with oesophageal cancer who undergo neoadjuvant chemoradiotherapy have no evidence of tumour in the resected specimen (complete pathological response). Those who do not respond have a poor 5-year survival compared with complete responders, regardless of whether or not they undergo surgery. Selecting for surgery only those who have a response to neoadjuvant therapy has the potential to improve overall survival as well as to rationalize the management of non-responders. This study assessed the accuracy of oesophagogastroscopy in this setting. Methods: A prospective database of 804 patients undergoing oesophageal resection for carcinoma was reviewed. Endoscopic assessment of the response to neoadjuvant therapy in 100 consecutive patients was compared with the pathological assessment of response. The survival for each level of response was compared. Results: At endoscopy 30 patients were considered to have had a complete response. This was confirmed pathologically in 15 patients. Survival was improved in those with a pathologically confirmed complete response (3-year survival rate 62.4 (s.e. 12.9) per cent) compared with non-responders (16.3 (s.e. 6.6) per cent). Those with microscopic residual disease also had an improved 3-year survival rate (46.3 (s.e. 12.2) per cent); however, oesophagogastroscopy failed to identify this subset. Conclusion: Oesophagogastroscopy may be useful in the assessment of tumour response to neoadjuvant therapy. However, owing to its poor accuracy patients should not be excluded from further therapeutic intervention on the basis of this assessment alone.

Efficient factorial experiments when the data are spatially correlated

Factorial experiments with spatially arranged units occur in many situations, particularly in agricultural field trials. The design of such experiments when observations are spatially correlated is investigated in this paper. We show that having a large number of within-factor level changes in rows and columns is important for efficient and robust designs, and demonstrate how designs with these properties can be constructed. (C) 2003 Elsevier B.V. All rights reserved.

Metabolic syndrome and associated factors in a population-based sample of schoolchildren in Colombia: The FUPRECOL Study

In contrast to the definition of metabolic syndrome (MetS) in adults, there is no standard definition of MetS in pediatric populations. We aimed to assess the differences in the prevalence of MetS in children and adolescents aged 9–17 years in the city of Bogota (Colombia) using four different operational definitions for these age groups and to examine the associated variables. A total of 673 children and 1,247 adolescents attending public schools in Bogota (54.4% girls; age range 9–17.9 years) were included. The prevalence of MetS was determined by the definitions provided by the International Diabetes Federation (IDF) and three published studies by Cook et al., de Ferranti et al., and Ford et al. The prevalence of MetS was 0.3%, 6.3%, 7.8%, and 11.0% according to the IDF, Cook et al., Ford et al., and de Ferranti et al. definitions, respectively. The most prevalent components were low high-density lipoprotein cholesterol and high triglyceride levels, whereas the least prevalent components were abdominal obesity and hyperglycemia. Overall, the prevalence of MetS was higher in obese than in non-obese schoolchildren. In conclusion, MetS diagnoses in schoolchildren strongly depend on the definition chosen. These findings may be relevant to health promotion efforts for Colombian youth to develop prospective studies and to define which cut-offs are the best indicators of future morbidity.

Huippuyksilöitä ja toimikuntia

Kirjoittaja on Helsingin yliopiston kulttuurimaantieteen dosentti, jolta ilmestyi juuri teos "Suomen Akatemian historia 1-3, Osa 1. Huippuyksilöitä ja toimikuntia 1948-1969" (SKS). Kirjoitus perustuu puheeseen kirjan julkistamistilaisuudessa 18.5.