1000 resultados para 128-794
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Servicios registrales
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UANL
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Este artículo presenta una revisión general, desde un punto de vista institucional y normativo, de la puesta en práctica de la Ley 128 de 1994, por la cual se expide la Ley Orgánica de las Áreas Metropolitanas en Colombia. Aquí se exploran algunos aciertos y fracasos de esta regulación frente al avance de las formas metropolitanas y regionales en el país durante los últimos años, proponiendo además algunos elementos de discusión para el fortalecimiento de estas áreas metropolitanas y otras figuras sub-regionales, desde consideraciones institucionales, financieras y de gestión.-----This essay provides an overview from an institutional and regulatory standpoint, of the implementation of Law 128/1994 by which the Organic Law of Metropolitan Areas in Colombia is enacted. Certain achievements and failures of this regulation are explored in face of the progress of metropolitan and regional forms in Colombia during the last years, and discussion elements for strengthening such metropolitan and other subregional areas are proposed from institutional, financial, and management considerations.
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We aimed to evaluate the frequency of Kaposi sarcoma (KS)-associated herpesvirus (KSHV) infection in KS lesions in patients from Brazil. In addition, expression of human bcl-2, cleaved caspase-3, and KSHV latency-associated nuclear antigen (LANA)-1 in tumors was evaluated using inummohistochemical analysis. We studied 64 KS cases, classified as follows: classical, 20 (31 %); iatrogenic, 2 (3 %); AIDS-associated, 25 (39%); and not otherwise specified (lack of information about HIV status), 17 (27%). KSHV was detected by polymerase chain reaction (PCR) in 61 cases (95%); 40 cases (63%) were KSHV+ by PCR and immunohistochemical analysis for LANA-L Immunoexpression of bcl-2 was detected in 47 cases (73%). Only a few cells in 15 cases (23%) of KS had demonstrable immunostaining for cleaved caspase-3. These results further support the association of KSHV with all KS forms. Cleaved caspase-3 in KS tumors was infrequent, which may reflect the inhibition of apoptosis owing to bcl-2 overexpression observed in the majority of KS tumors.