Value-based Reference Marketing in a Small Process Industry Software and Service Company

This master’s thesis was done for a small company, Vipetec Oy, which offers specialized technological services for companies mainly in forest industry. The study was initiated partly because the company wants to expand its customer base to a new industry. There were two goals connected to each other. First was to find out how much and what kind of value current customers have realized from ATA Process Event Library, one of the products that the company offers. Second was to determine the best way to present this value and its implications for future value potential to both current and potential customers. ATA helps to make grade and product changes, starting after machine downtime, and recovery from production break faster for customers. All three events sometimes occur in production line. The faster operation results to savings in time and material. In addition to ATA Vipetec also offers other services related to development of automation and optimization of controls. Theoretical part concentrates on the concept of value, how it can be delivered to customers, and what kind of risk customer faces in industrial purchasing. Also the function of reference marketing towards customers is discussed. In the empirical part the realized value for existing customers is evaluated based on both numerical data and interviews. There’s also a brief case study about one customer. After that the value-based reference marketing for a target industry is examined through interviews of these potential customers. Finally answers to the research questions are stated and compared also to the theoretical knowledge about the subject. Results show that those customers’ machines which use the full service concept of ATA usually are able to save more time and material than the machines which use only some features of the product. Interviews indicated that sales arguments which focus on improved competitive status are not as effective as current arguments which focus on numerical improvements. In the case of potential customers in the new industry, current sales arguments likely work best for those whose irregular production situations are caused mainly by fault situations. When the actions of Vipetec were compared to ten key elements of creating customer references, it was seen that many of them the company has either already included in its strategy or has good chances to include them with the help of the results of this study.

Vammaisuus hyvinvointivaltiossa. Invalideiksi, vajaamielisiksi tai kehitysvammaisiksi määriteltyjen kansalaisasema suomalaisessa vammaispolitiikassa 1940-luvun taitteesta vuoteen 1987

Tutkimuksessa tarkastellaan vammaisiksi määriteltyjen ihmisten kansalaisasemaa suomalaisessa toisen maailmansodan jälkeisessä vammaispoliittisessa keskustelussa. Analyysissa huomioidaan suomalaisen vammaishuollon molemmista päälinjoista, eli invalidihuollosta sekä vajaamielis- ja kehitysvammahuollosta, käydyt keskustelut. Tutkimuksen aikarajauksena toimii niin kutsuttu invalihuollon kausi, joka ulottui lakisääteisen vammaishuollon tarpeesta 1940-luvun taitteessa virinneestä keskustelusta vuoteen 1987, jolloin säädettiin periaatteiltaan edeltävään lainsäädäntöön verrattuna uudenlainen laki vammaisuuden perusteella järjestettävistä palveluista ja tukitoimista. Vammaisuuden käsitettä lähestytään tutkimuksessa yhtenä modernin sosiaalipoliittisen lainsäädännön kategorioista, jotka ovat vapauttaneet kansalaisen velvollisuudesta itsensä ja perheensä elättämiseen ja oikeuttaneet hänet toimeentulossaan sosiaaliturvaan. Tutkimuksessa pyritään hahmottamaan millaiseksi tutkimuksen kohteena olevien vammaisten ryhmien kansalaisasema tutkimusajankohtana ymmärrettiin. Tarkastelussa keskitytään kansalaisuuden käsitteen niin kutsuttuun aineellisoikeudelliseen sisältöön analysoimalla tutkimuksen kohteena olevissa keskusteluissa esiintyneitä kansalaisuuden ideaaleja ja käsityksiä kansalaisen ja valtion suhteesta. Tutkimusaihetta lähestytään etsimällä vastausta kysymyksiin 1) Mihin yhteiskunnallisiin ongelmiin invalidihuollosta ja vajaamielis- tai 312 kehitysvammahuollosta käydyissä asiantuntijakeskusteluissa haettiin ratkaisuja? 2) Millaisia tavoitteita huollolle asetettiin? 3) Millaiseksi hahmotettiin huollon kohderyhmien asema ja tehtävät yhteiskunnassa? Analyysissa keskitytään huollosta käydyn asiantuntijakeskustelun tarkasteluun. Tutkimuksen keskeisin lähdeaineisto muodostuu tutkimusajankohdan vammaishuoltoa käsittelevästä lainsäädännöstä, sen valmistelun materiaaleista sekä vammaisjärjestöjen ja muiden alan asiantuntijoiden vammaishuollosta julkisuudessa käymästä keskustelusta. Tutkimuksessa esitetään, että suomalaisen vammaispolitiikan ja vammaisten kansalaisaseman kehityksessä on tutkimusajankohtana erotettavissa kolme vaihetta: 1) 1940–1950-lukujen yhteiskunnan rationalisointia ja sosiaalisten ongelmien vähentämistä painottaneella ennaltaehkäisevän huoltopolitiikan kaudella vammaiset ihmiset hahmotettiin yhteiskunnan reunamilla tai ulkopuolella olevaksi erityisryhmäksi, joka tuli pyrkiä huollon toimenpiteillä integroimaan omalle paikalleen yhteiskunnan kokonaisuuteen. 2) 1960-luvun kuntoutusideaalin laajenemisen kaudella vammaishuollon julkilausutuksi tavoitteeksi omaksuttiin yksilön edun ajaminen. 3) 1970–1980-lukujen normalisaation periaatetta painottaneessa vammaispolitiikassa tavoitteeksi otettiin vammaisille tarkoitettujen erityisjärjestelmien purkaminen sekä vammaisten tasa-arvoisen kansalaisaseman turvaaminen heidän osallistumismahdollisuuksiaan parantavilla tukitoimenpiteillä.

Exaggerated blood pressure response during the exercise treadmill test as a risk factor for hypertension

Exaggerated blood pressure response (EBPR) during the exercise treadmill test (ETT) has been considered to be a risk factor for hypertension. The relationship of polymorphisms of the renin-angiotensin system gene with hypertension has not been established. Our objective was to evaluate whether EBPR during exercise is a clinical marker for hypertension. The study concerned a historical cohort of normotensive individuals. The exposed individuals were those who presented EBPR. At the end of the observation period (41.7 months = 3.5 years), the development of hypertension was analyzed within the two groups. Genetic polymorphisms and blood pressure behavior were assessed as independent variables, together with the classical risk factors for hypertension. The I/D gene polymorphism of the angiotensin-converting enzyme and M235T of angiotensinogen were ruled out as risk factors for hypertension. EBPR during ETT is not an independent influence on the chances of developing hypertension. No differences were observed between the hypertensive and normotensive individuals regarding gender (P = 0.655), skin color (P = 0.636), family history of hypertension (P = 0.225), diabetes mellitus (P = 0.285), or hypertriglyceridemia (P = 0.734). The risk of developing hypertension increased with increasing body mass index (BMI) and advancing age. The risk factors, which independently influenced the development of hypertension, were age and BMI. EBPR did not constitute an independent risk factor for hypertension and is probably a preclinical phase in the spectrum of normotension and hypertension.

Aineettomien riskien hallinta – case Itä-Suomen Biopankki

Aineeton pääoma nähdään organisaation keskeisenä kilpailutekijänä ja voimavarana. Se voi kuitenkin joissain tilanteissa olla organisaatiolle myös rasite tai jopa menestymistä heikentävä tekijä. Tutkimuksen tavoitteena oli laatia biopankin riskienhallinnalle malli, joka huomioi toimintaan vaikuttavat aineettomat riskitekijät ja toimii strategisena johtamisen ja toiminnan kehittämisen työvälineenä. Tutkimus toteutettiin tapaustutkimuksena, jossa käytettiin konstruktiivista tutkimusotetta. Biopankille luotiin konstruktio, riskienhallintamalli, jolla pyrittiin ratkaisemaan reaalimaailman ongelma ja samalla luomaan kontribuutiota tieteenalalle. Biopankki on uudentyyppinen organisaatio, joka kerää, hallinnoi ja säilyttää biologisia ihmisperäisiä näytteitä ja niihin liittyviä tietoja tulevaa tutkimusta varten. Toiminnan riskien taustasyyt ovat usein aineettomia, kuten toimintakulttuuri, asenne, osaaminen tai motivaatio. Tutkimuksessa löydettiin uusia biopankin toimintaan kytkeytyviä aineettomia riskejä koko aineettoman pääoman alueelta ja määriteltiin riskitasoihin perustuva lähestymistapa riskien hallintaan. Konstruktio aineettomien riskien hallintamalliksi sai selkeää vahvistusta tutkimuksen aineistosta, ja se voi toimia organisaation kehittämisen pohjana. Riskikartan luominen ja riskien arviointi ovat tekohetken poikkileikkauksia tilanteesta. Organisaation toiminta ja siihen kohdistuvat riskit ja mahdollisuudet muuttuvat ja kehittyvät. Riskien tunnistaminen lisää tietoa organisaatiosta ja sen toimintaympäristöstä, mikä luo puitteet myös uusien mahdollisuuksien tunnistamiselle. Sopivan riskienhallintamallin avulla voidaan löytää kilpailuetua suhteessa muihin organisaatioihin. Kilpailuetuna voi toimia myös muita parempi riskinkantokyky esimerkiksi toiminnan joustavuuden kautta.

Technological properties of precooked flour containing coffee powder and rice by thermoplastic extrusion

Although Brazil is a country of tradition in both the production and consumption of coffee, the most of the coffee is consumed as a beverage, which reduces greatly the competitiveness on international market, for reducing the chances of supplying the product under other forms of consumption. Owing to that, the aim of this study was developing a precooked mixed flour containing coffee powder and rice for use in coffee flavored products. Mixtures of rice and coffee in the proportions of 900:100, 850:150 and 800:200 g, respectively, were processed in a single screw extruder (Brabender DS-20, Duisburg, German) and the effect of the extrusion process on the variables moisture content (16%, 18% and 20%) and temperature in the third extruding zone (140 °C, 160 °C and 180 °C) was studied. The results for expansion index ranged from 2.91 to 11.11 mm in diameter; the water absorption index from 4.59 to 6.33 g gel/g sample and the water solubility index varied from 4.05% to 8.57%. These results showed that, despite coffee powder influenced the variables studied, the expanded product after milling resulted in a extruded mixture with good absorption and water solubility indices, which favors the use of the precooked mixed flour for human consumption.

Etelä-Karjalan sosiaali- ja terveyspiirin rakentuminen ja organisaation kehittämisen haasteet

Tutkimuksen tavoitteena on selvittää, mitkä nähtiin keskeisiksi tekijöiksi nykymuotoisen Etelä-Karjalan sosiaali- ja terveyspiirin (EKSOTE) rakentumiselle, miten sosiaalihuollon, perusterveydenhuollon ja erikoissairaanhoidon yhdistäminen samaan organisaatioon mahdollistaa parempien palvelujen tuottamisen, mitkä ovat organisaatiomuutoksen läpiviennin keskeiset haasteet sekä mitkä ovat poliittisen ohjauksen merkitys ja mahdollisuudet EKSOTESSA. Tutkimus on laadullinen tapaus- eli casetutkimus. Tutkimusmenetelminä käytetään teemahaastatteluja ja puolistrukturoituja lomakehaastatteluja. Tutkimuksen keskeinen teoreettinen viitekehys on New Public Management. Tutkimuksen keskeisenä tuloksena esitetään, että EKSOTEN synnyn taustalla oli aito halu parantaa sosiaalihuollon ja terveydenhuollon palveluita koko Etelä-Karjalan alueella. Tämä tapahtui siten, että sosiaalihuolto, perusterveydenhuolto ja erikoissairaanhoito yhdistettiin saman organisaatioon ja kaikkien kuntien tämän alan henkilöstö siirtyi kunnista EKSOTEN palvelukseen. Organisaation syntyminen edellytti vahvaa poliittista ohjausta. EKSOTESSA on paljon eritysosaamista, joka on käytettävissä koko Etelä- Karjalan alueen asukkaiden hyväksi. Organisaatiomuutoksessa on mukana keskeiset New Public Managementin periaatteet eli tehokkuusperiaatteet sekä palvelujen laadun, asiakaskeskeisyyden ja henkilöstön palkitsemisen kysymykset.

Motivo de "escolha" de diálise peritoneal: exaustão de acesso vascular para hemodiálise?

INTRODUÇÃO: Pouco se conhece sobre a evolução de pacientes que iniciam DP como única alternativa. OBJETIVOS: Descrever o perfil clínico-demográfico e a ocorrência de peritonite em uma amostra de pacientes convertidos de HD para DP por exaustão de acesso vascular. MÉTODOS: Revisão dos prontuários de todos os pacientes do programa de DP do HGRS. RESULTADOS: Foram estudados 22 pacientes com idade mediana de 47,9 anos, 54,5% de homens, 84,2% de negros ou mulatos, 68,2% procedentes do interior da Bahia. DP foi a modalidade inicial de TRS em apenas quatro pacientes. Os 18 pacientes restantes iniciaram TRS através de HD; neste grupo, predominou o início de HD de forma emergencial e através de cateter duplo-lúmen (CDL). Em uma mediana de 7,7 meses em HD, a maioria dos pacientes (64,7%) usou mais de quatro CDL. Em apenas 7/18 (39%) pacientes, a conversão de HD para DP foi feita por escolha do paciente; na maioria dos casos, 11/18 (61%), o motivo de conversão foi exaustão de acesso vascular para HD. Peritonite foi mais frequente nos pacientes que entraram em HD por exaustão de acesso vascular que no restante do grupo. CONCLUSÕES: O início de TRS de forma emergencial através de HD utilizando CDL pode levar a uma rápida exaustão de acesso vascular, deixando a DP como única alternativa viável. Este modo inadequado de "seleção" de pacientes para DP está associado a maiores chances de ocorrência de peritonite.

Impacto da função retardada do enxerto pancreático no transplante simultâneo pâncreas-rim

OBJETIVO: O transplante pâncreas-rim é efetivo para pacientes com doença renal crônica terminal e diabetes mellitus insulino-dependente. A função retardada do enxerto pancreático é condição frequente exercendo impacto significativo nos resultados em curto prazo dos transplantes pâncreas-rim. O objetivo foi analisar o impacto da função retardada do enxerto pancreático no transplante pâncreas-rim. MÉTODOS: Análise retrospectiva de 180 receptores de transplante pâncreas-rim, incluindo dados demográficos dos doadores e dos receptores, a reatividade contra painel, a incidência de rejeição aguda e as sobrevidas do paciente e dos enxertos pancreático e renal. RESULTADOS: A incidência de função retardada do enxerto pancreático foi 11%. A idade do receptor superior a 45 anos apresentou associação com o risco de desenvolvimento de função retardada do enxerto pancreático (Razão de chances 2,26; p < 0,05). Os pacientes com função retardada do enxerto pancreático apresentaram maior incidência de rejeição aguda renal (47 versus 24%; p < 0,05), glicemia de jejum alterada (25 versus 5%; p < 0,05) e média de hemoglobina glicada (5,8 versus 5,4%; p < 0,05) ao final do primeiro ano de acompanhamento em relação aos pacientes sem função retardada do enxerto pancreático. Não houve diferenças estatisticamente significativas entre os grupos de pacientes com e sem função retardada do enxerto pancreático quanto à sobrevida do paciente (95 versus 88,7%; p = 0,38), do enxerto pancreático (90 versus 85,6%; p = 0,59) e do enxerto renal (90 versus 87,2%; p = 0,70), respectivamente, nesse mesmo período. CONCLUSÃO: A função retardada do enxerto pancreático não exerceu impacto significativo nos resultados em curto prazo dos transplantes pâncreas-rim desta casuística. Embora a função retardada do enxerto pancreático não tenha influenciado a sobrevida do enxerto pancreático ao final do primeiro ano após o transplante, contribuiu para a disfunção pancreática precoce, indicando maior necessidade de uso de insulina e hipoglicemiantes orais.

Escore de avaliação de risco pré-transplante: metodologia e a importância das características socioeconômicas

Introdução: O transplante renal é realizado em condições de urgência em uma população com elevado risco perioperatório. Instrumentos de avaliação de risco pré-transplante nesta população são escassos. Objetivo: Construir um escore com variáveis pré-transplante para estimar a probabilidade de sucesso do transplante renal, definido como sobrevida do receptor e do enxerto, com creatinina < 1,5 mg/dl no 6º mês. Métodos: Análise das variáveis de pacientes de um centro único e especializado em transplante renal em São Paulo. A regressão logística foi utilizada para construção da equação com as variáveis capazes de estimar a probabilidade de sucesso. Atribuímos pontos inteiros às variáveis para a construção do escore. Resultados: Dos 305 pacientes analisados, 176 (57,7%) atingiram o sucesso. Das 23 variáveis identificadas pela análise univariada, 21 foram incluídas no modelo de regressão logística e as 10 que se mantiveram independentemente associadas com o sucesso foram utilizadas na construção do escore. Quatro destas 10 variáveis eram socioeconômicas. Foi ótimo (área sob a curva ROC = 0,817) o poder de discriminação entre os grupos sucesso e não sucesso e adequado (teste de Hosmer e Lemeshow = 0,672) o grau de concordância entre as frequências das probabilidades estimadas pela equação e as frequências das probabilidades reais observadas. Houve correlação (0,982) entre as probabilidades estimadas via sistema de pontuação e regressão logística. Conclusão: O escore de pontos apresentado simplificou a estratificação do risco do candidato ao transplante conforme a probabilidade de sucesso. As variáveis socioeconômicas exerceram influência no sucesso, demonstrando a necessidade da criação de instrumentos prognósticos utilizando as variáveis clínico-demográficas da nossa população.

Determinantes da recuperação do emprego formal no Brasil: evidências para o período 2001/2005 e hipoteses para uma agenda de pesquisa

Decisive factors affecting the recent increase in formal employment in Brazil. This paper gives a general overview of the evolution of labour market indicators between 1995 and 2005 in Brazil. It shows an overall increase in formal employment rates from 2001 to 2005, as opposite to what had happened from 1995 to 1999. It is argued that such recent trends might indicate the reconfiguration of the labour market in better terms, with potential positive consequences to the finance performance of the Social Security sector. The paper also examines some of the major factors associated with this new trend and their chances to maintain such tendency in the near future. It's important to notice that all of them may be subject to some kind of political management by the State. In other words, we suggest that there are suficient instruments and operative skills in the Brazilian State to make these and others factors work in favour of a more persistent strategy of development with social inclusion through labour.

University students’ regulation of learning and text processing – examples from medical and teacher education

The general aim of the thesis was to study university students’ learning from the perspective of regulation of learning and text processing. The data were collected from the two academic disciplines of medical and teacher education, which share the features of highly scheduled study, a multidisciplinary character, a complex relationship between theory and practice and a professional nature. Contemporary information society poses new challenges for learning, as it is not possible to learn all the information needed in a profession during a study programme. Therefore, it is increasingly important to learn how to think and learn independently, how to recognise gaps in and update one’s knowledge and how to deal with the huge amount of constantly changing information. In other words, it is critical to regulate one’s learning and to process text effectively. The thesis comprises five sub-studies that employed cross-sectional, longitudinal and experimental designs and multiple methods, from surveys to eye tracking. Study I examined the connections between students’ study orientations and the ways they regulate their learning. In total, 410 second-, fourth- and sixth-year medical students from two Finnish medical schools participated in the study by completing a questionnaire measuring both general study orientations and regulation strategies. The students were generally deeply oriented towards their studies. However, they regulated their studying externally. Several interesting and theoretically reasonable connections between the variables were found. For instance, self-regulation was positively correlated with deep orientation and achievement orientation and was negatively correlated with non-commitment. However, external regulation was likewise positively correlated with deep orientation and achievement orientation but also with surface orientation and systematic orientation. It is argued that external regulation might function as an effective coping strategy in the cognitively loaded medical curriculum. Study II focused on medical students’ regulation of learning and their conceptions of the learning environment in an innovative medical course where traditional lectures were combined wth problem-based learning (PBL) group work. First-year medical and dental students (N = 153) completed a questionnaire assessing their regulation strategies of learning and views about the PBL group work. The results indicated that external regulation and self-regulation of the learning content were the most typical regulation strategies among the participants. In line with previous studies, self-regulation wasconnected with study success. Strictly organised PBL sessions were not considered as useful as lectures, although the students’ views of the teacher/tutor and the group were mainly positive. Therefore, developers of teaching methods are challenged to think of new solutions that facilitate reflection of one’s learning and that improve the development of self-regulation. In Study III, a person-centred approach to studying regulation strategies was employed, in contrast to the traditional variable-centred approach used in Study I and Study II. The aim of Study III was to identify different regulation strategy profiles among medical students (N = 162) across time and to examine to what extent these profiles predict study success in preclinical studies. Four regulation strategy profiles were identified, and connections with study success were found. Students with the lowest self-regulation and with an increasing lack of regulation performed worse than the other groups. As the person-centred approach enables us to individualise students with diverse regulation patterns, it could be used in supporting student learning and in facilitating the early diagnosis of learning difficulties. In Study IV, 91 student teachers participated in a pre-test/post-test design where they answered open-ended questions about a complex science concept both before and after reading either a traditional, expository science text or a refutational text that prompted the reader to change his/her beliefs according to scientific beliefs about the phenomenon. The student teachers completed a questionnaire concerning their regulation and processing strategies. The results showed that the students’ understanding improved after text reading intervention and that refutational text promoted understanding better than the traditional text. Additionally, regulation and processing strategies were found to be connected with understanding the science phenomenon. A weak trend showed that weaker learners would benefit more from the refutational text. It seems that learners with effective learning strategies are able to pick out the relevant content regardless of the text type, whereas weaker learners might benefit from refutational parts that contrast the most typical misconceptions with scientific views. The purpose of Study V was to use eye tracking to determine how third-year medical studets (n = 39) and internal medicine residents (n = 13) read and solve patient case texts. The results revealed differences between medical students and residents in processing patient case texts; compared to the students, the residents were more accurate in their diagnoses and processed the texts significantly faster and with a lower number of fixations. Different reading patterns were also found. The observed differences between medical students and residents in processing patient case texts could be used in medical education to model expert reasoning and to teach how a good medical text should be constructed. The main findings of the thesis indicate that even among very selected student populations, such as high-achieving medical students or student teachers, there seems to be a lot of variation in regulation strategies of learning and text processing. As these learning strategies are related to successful studying, students enter educational programmes with rather different chances of managing and achieving success. Further, the ways of engaging in learning seldom centre on a single strategy or approach; rather, students seem to combine several strategies to a certain degree. Sometimes, it can be a matter of perspective of which way of learning can be considered best; therefore, the reality of studying in higher education is often more complicated than the simplistic view of self-regulation as a good quality and external regulation as a harmful quality. The beginning of university studies may be stressful for many, as the gap between high school and university studies is huge and those strategies that were adequate during high school might not work as well in higher education. Therefore, it is important to map students’ learning strategies and to encourage them to engage in using high-quality learning strategies from the beginning. Instead of separate courses on learning skills, the integration of these skills into course contents should be considered. Furthermore, learning complex scientific phenomena could be facilitated by paying attention to high-quality learning materials and texts and other support from the learning environment also in the university. Eye tracking seems to have great potential in evaluating performance and growing diagnostic expertise in text processing, although more research using texts as stimulus is needed. Both medical and teacher education programmes and the professions themselves are challenging in terms of their multidisciplinary nature and increasing amounts of information and therefore require good lifelong learning skills during the study period and later in work life.

Diel patterns and tissue-specificity of environmental responses in fish

Humans are profoundly changing aquatic environments through climate change and the release of nutrients and chemicals. To understand the effects of these changes on natural populations, knowledge on individuals’ environmental responses is needed. At the molecular level, the environmental responses are partly mediated by chances in messenger RNA and protein levels. In this thesis I study messenger RNA and protein responses to an assortment of environmental stressors in fish. As daily (diel) rhythms are known to be ubiquitous in different tissues, I particularly focus on diel patterns in the responses. The studied species are the three-spined stickleback (Gasterosteus aculeatus L.) and the Arctic char (Salvelinus alpinus L.), both of which have circumpolar distribution in the Northern hemisphere. In the first two studies, three-spined sticklebacks were exposed to both the non-steroidal anti-inflammatory drug diclofenac and low-oxygen conditions (hypoxia), and their responses measured at separate time points in the liver and gills. The results show how the seemingly unrelated environmental stressors, hypoxia and anti-inflammatory drugs, can have harmful combined effects that differ from the effects of each stressor alone. Moreover, both stressors disturbed natural diel patterns in gene expression. In the third study, I studied the responses of three-spined sticklebacks to two test chemicals: one used in hormonal medicine (17α-ethinyl-oestradiol) and one used as a plasticizer and solvent chemical (di-n-butyl phthalate). The results suggest that the phthalate can affect genes related to spermatogenesis in fish testes, while estrogen-mimicking compounds can lead to numerous disturbances in the endocrine system. In the final study, the temperature-dependence of diel rhythms in messenger RNA levels were evaluated in the liver tissue of the Arctic char, a cold-adapted salmonid. The results show that cold acclimation repressed diel rhythms in gene expression compared to warm-acclimated fish, in which the expression of hundreds of genes was rhythmic, suggesting the circadian clock of the Arctic fish species can be sensitive to temperature. Overall, the results of the thesis indicate that fishes’ responses to abiotic factors interact with their diel rhythms, and more studies on the consequences of these interactions are needed to comprehensively understand human impacts on ecosystems.

Tuulivoimaliiketoimintaan liittyviä epävarmuustekijöitä

Diplomityön tavoitteena oli selvittää tuulivoimatuotannon epäsymmetrisyyden vaikutuksia liiketoiminnalle. Tarkastelun kohteena oli tuotetun energian sekä tuulivoimatuotannosta maksettavan korvauksen keskinäinen epäsymmetria. Työssä asiaa tarkasteltiin esimerkki tuulivoimalaitoksen avulla. Tarkastelujaksoksi työssä rajattiin ajanjakso 2014 tammikuusta vuoden 2015 kesäkuuhun. Tämän lisäksi työssä perehdyttiin tuotetun sähkön hinnan suojausstrategioihin, tuotannon häviötekijöihin sekä tasesähkön aiheuttamien kustannusten kehitykseen. Työn tulosten perusteella tuulivoimaliiketoiminta tulee kokemaan epävakauden lisääntymistä. Tuulivoimatuotannon epävarmuus johtuu heikosta pitkän aikavälin ennustettavuudesta, joka koostuu aikaisemmin mainituista tuotannon ja sähkön markkinahinnan välisestä epäsymmetrisyydestä. Työssä käsitellään tuulivoimatuotannon ajallista vaihtelua, joka ilmentää hyvin tuulivoimatuotannon perimmäistä olemusta. Työn lopputuloksena saatiin kuvaus tuotantojen ajallisesta jakautuneisuudesta, joiden pohjalta yritys voi suunnitella suojausstrategioita työssä esiteltyjen johdannaistuotteiden avulla. Edellisten loppupäätelmien lisäksi työssä perehdyttiin häviöiden sekä tasesähkökustannusten taloudellisiin vaikutuksiin sekä kehityssuuntiin tulevaisuudessa.

Pk-yrityksen jatkajaksi mielivän kasvuorientaatio

In Finland, entrepreneurship policy priorities are encouragement and support for business innovation, growth and internationalization. SMEs are having economically significant employment and wealth creation potential. During the following years, there will be plenty of businesses for sale on the Finnish market. The challenge is to find and identify growth-oriented, talented, innovative, capable to rapid experimentation new entrepreneurs, in whose hands the company's growth targets are going to be realized. In these research is examined frameworks of the company's growth and the factors influencing growth on the basis of previous studies and literature. In addition, the aim is to create a suitable framework to identify the early stage of entrepreneurs, who are growth-oriented. The other aim is create the supposed directions of influences for growth-orientation. The objectives of the work of the results is to act as an umbrella topic, contextual analysis and forming a new applied framework for further studies. The results of these research are the background variables, the desire for growth are composed of motives, attitudes and desires; the skills for growth are composed of capabilities, experiences, self-efficacy and the willingness for risk-taking; the opportunities for growth are composed of IPR, financing, megatrends and other observed chances.

Cartulaire de l'abbaye de Troarn [diocèse de Bayeux].

Acquis le 22 février 1842 par don de M. Auguste Le Prevost; cf. B.n.F., département des Manuscrits, registre des acquisitions 1833-1848, n° 3067; — note "Ce manuscrit, sorti des archives de l'abbaie de Troarn à l'époque de la Révolution, a été acquis par mon ami Frédéric Galeron des héritiers de monsieur l'abbé de La Rue, qui y avait inscrit quelques notes. Au moment où il fut enlevé aux recherches locales qu'il cultivait avec tant de zèle et de succès, mon excellent ami me fit l'honneur de me le léguer par son testament. Désirant concourir autant qu'il peut dépendre de moi, à compléter la collection des mss. relatifs à l'histoire et à la topographie de la France, que renferme la Bibliothèque du roi de Paris; convaincu par une triste expérience des inconvénients graves et des chances de destruction que présente le passage de ces précieux documents dans des collections privées, où ils restent trop souvent inaccessibles aux amis de l'histoire; voulant enfin rendre un hommage durable à la mémoire d'un ami dont le souvenir me sera à jamais regrettable et cher, et entrer dans les vues généreuses qui l'ont engagé à me léguer ce cartulaire de l'abbaie de Troarn; je déclare faire hommage du présent ms. à la Bibliothèque du roi de Paris, désirant qu'il y demeure comme un monument authentique de ma reconnaissance pour le bienveillant accueil que j'y ai constamment reçu, de ma pieuse vénération pour la mémoire de l'excellent ami de qui je le tiens et de ma sollicitude pour les progrès futurs du genre de recherches auquel j'ai voué ma vie. Paris, ce 17 février 1842. A. Le Prevost" (IIv); cf. Delisle, Cab. des mss., II, 298.