MODELO PARA EL ANÁLISIS DEL FORTALECIMIENTO SOCIOECONÓMICO DE LAS MIPYMES EN COSTA RICA

Resumen El efecto de múltiples variables sobre el bienestar social y económico en las pequeñas y medianas empresas puede ser analizado tomando en cuenta las condiciones sistémicas en el modelo propuesto. Este artículo ofrece un marco teórico o modelo para comprender y explicar la relación entre las variables independientes tales como el crédito, mercados, empresariedad, entre otras, y la variable dependiente tal como los ingresos, la producción o el empleo. El propósito fundamental es organizar la mayoría de variables para determinar porqué los ingresos y el empleo no es sostenible par alas pequeñas y medianas empresas. Por lo tanto, factores sociales, económicos así como culturales e institucionales han sido incluidos en el análisis. El modelo desarrollado puede ayudar a mejorar el diseño de estrategias para lograr el éxito de las pequeñas y medianas empresas y el marco de política pública para el gobierno en Costa Rica.   Abstract The effect of multiples variables on the social and economic welfare in the Small and medium size enterprises can be analized taking in account systemic conditions in this model.This paper offers a theoretical framework or model to understand and explain the relationship between independent variables such as credit, markets, entrepreneurship, among others, and dependent variable such as incomes, production or employment rate. The main idea is organize the all variables to determine why the income or employment level is not sustainable for SMEs. Therefore, social and economic factors as well as cultural and institutional components have been included in this analysis. The developed model can help to improve design and management of competitiveness strategies for SMEs and policy framework for the government in Costa Rica.

Teachers' legitimacy: Effects of justice perception and social comparison processes

Background. Teachers’ legitimacy is central to school functioning. Teachers’ justice, whether distributive or procedural, predicts teachers’ legitimacy. Aims. What is still do be found, and constitutes the goal of this paper, is whether unjust treatment by a teacher affects the legitimacy of the teacher differently when the student knows that the teacher was fair to a peer (comparative judgement) or when the student does not have that information (autonomous judgement). Samples. A total of 79 high school students participated in Study 1; 75 high school students participated in Study 2. Methods. Two experimental studies with a 2 justice valence (just, unjust) 9 2 social comparison processes (autonomous judgements, comparative judgements) betweenparticipants design were conducted. Study 1 addressed distributive justice and Study 2 addressed procedural justice. The dependent variable was teachers’ legitimacy. Results. In both studies, situations perceived as just led to higher teachers’ legitimacy than situations perceived as unjust. For the distributive injustice conditions, teachers’ legitimacy was equally lower for autonomous judgement and comparative judgement conditions. For procedural injustice, teachers’ legitimacy was lower when the peer was treated justly and the participant was treated unfairly, compared with the condition when the participants did not know how the teacher treated the peer. Conclusions. We conclude that teachers’ injustice affects teachers’ legitimacy, but it does it differently according to the social comparisons involved and the type of justice involved. Moreover, these results highlight that social comparisons are an important psychological process and, therefore, they should be taken into account in models of justice.

Efeitos do treinamento resistido com máquinas pneumáticas e resistência elástica progressiva na força, capacidade funcional e equilíbrio em mulheres idosas : um ensaio clínico randomizado

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Educação Física, Programa de Pós-Graduação Strictu-Sensu em Educação Física, 2015.

“Mais vale intervir, do que remediar" Cultura de segurança e resiliência: O futuro caminho das organizações

Dissertação de Mestrado apresentada ao Instituto Superior de Psicologia Aplicada para obtenção de grau de Mestre na especialidade de Psicologia Social e das Organizações.

Household portfolio allocation, risk attitudes and credit constraints : evidence from the eurozone

Mestrado em Economia Monetária e Financeira

An Analysis of the Factors that Influence Regional Economic Development Cooperation

This dissertation is a comparative case study of regional cooperation in the field of economic development. In the 21st century global economy, proponents of regionalism have put forth fresh arguments for collective action. A regional approach to economic development activity presents a classic social dilemma: How can local officials collectively improve the economic prospects of a region, and remain autonomous to act in the best interest of the local community? This research examines the role of social capital in overcoming this social dilemma. Three (3) comparable Metropolitan Statistical Areas (MSAs) form the empirical basis of this research. The Houston MSA, the Atlanta MSA and the Miami MSA present distinct variations of regionalized economic development activity. This dissertation seeks to explain this disparity in the dependent variable. The hypothesis is that accrued social capital is crucial to obtaining economic development cooperative agreements. This qualitative research utilized secondary demographic and economic databases, survey instruments, interviews, field observations, and a review of legislative and administrative decisions to formulate a clear understanding of the factors influencing the current state of regional economic development cooperation within each region. The study concludes that the legislative and executive decisions of state government exert inordinate influence on the capacity of local officials to cooperate regionally for economic development purposes.

Social Capital, HIV Risk Behavior and Substance Use among Recent Latino Immigrants in South Florida

Social capital, or social cohesion or group connectedness, can influence both HIV risk behavior and substance use. Because recent immigrants undergo a change in environment, one of the consequences can be a change in social capital. There may be an association among changes in social capital, and HIV risk behavior and substance use post immigration. The dissertation focused on the interface of these three variables among recent Latino immigrants (RLIs) in South Florida. The first manuscript is a systematic review of social capital and HIV risk behavior, and served as a partial background for the second and third manuscripts. Twelve papers with a measure of social capital as an independent variable and HIV risk as the dependent variable were included in the analysis. Eleven studies measured social capital at the individual level, and one study measured social capital at the group level. HIV risk was influenced by social capital, but the type of influence was dependent on the type of social capital and on the study population. Cognitive social capital, or levels of collective action, was protective against HIV in both men and women. The role of structural social capital, or levels of civic engagement/group participation, on HIV risk was dependent on the type of structural social capital and varied by gender. Microfinance programs and functional group participation were protective for women, while dysfunctional group participation and peer-level support may have increased HIV risk among men. The second manuscript was an original study assessing changes in social capital and HIV risk behavior pre to post immigration among RLIs in South Florida (n=527). HIV risk behavior was assessed through the frequency of vaginal-penile condom use, and the number of sexual partners. It was a longitudinal study using secondary data analysis to assess changes in social capital and HIV risk behavior pre immigration to two years post immigration, and to determine if there was a relationship between the two variables. There was an 8% decrease in total social capital (p ˂ .05). Reporting of ‘Never use’ of condoms in the past 90 days increased in all subcategories (p ˂ .05). Single men had a decrease in number of sexual partners (p ˂ .05). Lower social capital measured on the dimension of ‘friend and other’ was marginally associated with fewer sexual partners. The third manuscript was another original study looking at the association between social capital and substance use among RLIs in South Florida (n=527). Substance use with measured by frequency of hazardous alcoholic drinking, and illicit drug use. It was a longitudinal study of social capital and substance-use from pre to two years post immigration. Post-immigration, social capital, hazardous drinking and illicit drug use decreased (p˂.001). After adjusting for time, compared to males, females were less likely to engage in hazardous drinking (OR=.31, p˂.001), and less likely to engage in illicit drug use (OR=.67, p=.01). Documentation status was a moderator between social capital and illicit drug use. ‘Business’ and ‘Agency’ social capital were associated with changes in illicit drug use for documented immigrants. After adjusting for gender and marital status, on average, documented immigrants with a one-unit increase in ‘business’ social capital were 1.2 times more likely to engage in illicit drug use (p˂.01), and documented immigrants with one-unit increase in ‘agency’ social capital were 38% less likely to engage in illicit drug use (p˂.01). ‘Friend and other’ social capital was associated with a decrease in illicit drug use among undocumented immigrants. After adjusting for gender and marital status, on average, undocumented immigrants with a one-unit increase in ‘friend and other’ social capital were 45% less likely to engage in hazardous drinking and 44% less likely to use illicit drugs (p˂.01, p˂.05). Studying these three domains is relevant because HIV continues to be a public health issue, particularly in Miami-Dade County, which is ranked among other U.S. regions with high rates of HIV/AIDS prevalence. Substance use is associated with HIV risk behavior; in most studies, increased substance use is associated with increased chances of HIV risk behavior. Immigration, which is the hypothesized catalyst for the change in social capital, has an impact on the dynamic of a society. Greater immigration can be burdensome on the host country’s societal resources; however immigrants are also potentially a source of additional skilled labor for the workforce. Therefore, successful adaption of immigrants can have a positive influence on receiving communities. With Florida being a major receiver of immigrants to the U.S, this dissertation attempts to address an important public health issue for South Florida and the U.S. at large.

Perfil epidemiológico y análisis de la formulación antibiótica en pacientes con infección urinaria nosocomial en la Fundación Cardioinfantil en el año 2014

Introducción: La IVU es muy frecuenten en la (FCI - IC), Alrededor el 60% de los pacientes con diagnóstico de IVU nosocomial corresponden a gérmenes resistente, Desde el año 2010 el CLSI disminuyó los puntos de corte de sensibilidad en las enterobacteriaceae y removió la necesidad de tamizaje y confirmación de (BLEE), en el presente trabajo se pretende determinar el perfil epidemiológico de la formulación antibiótica en pacientes con IVU nosocomial. Diseño: Se realizó un estudio observacional analítico de corte transversal. Métodos: Se realizó un análisis univariado, bivariado y multivariado. El análisis bivariado y multivariado se realizó para determinar la medida de asociación teniendo en cuenta la formulación de Carbapenemico la variable dependiente, evaluándose mediante chi cuadrado. Resultados: Se revisaron 131 urocultivos, se incluyeron 116. Los aislamientos microbiológicos más frecuentemente encontrados fueron E. Coli y K. Pneumoniae, el 43.4% de los aislamientos, presentaron expresión de BLEE, 90% de los aislamientos fueron sensibles a Cefepime. La mayoría de los modelos obtenidos mostraron una fuerte asociación entre el reporte de BLEE en antibiograma con la formulación de carbapenémicos como terapia final OR 33,12 IC 95% (2,90 – 337,4). Conclusión: La epidemiologia de la IVU nosocomial en la FCI-IC no difiere de las referencias internacionales, no hay adherencia a las guías de manejo intrahospitalario y el reporte de la palabra BLEE en el antibiograma predice la formulación de antibiótico carbapenémico por el médico que lee el urocultivo

Avalição do impacto de uma biblioteca universitária

Neste estudo apresenta-se uma avaliação do impacto da Biblioteca da Faculdade de Ciências da Universidade do Porto (FCUP), na perspetiva dos estudantes e observando alguns dados relativos ao uso da Biblioteca FCUP. A investigação recorre a uma análise de métodos mistos, isto é, avalia dados qualitativos, que descrevem mas não mensuram as características, em especial as ações humanas, e dados quantitativos que apresentam forma numérica e revelam uma quantidade certa podendo ser sujeitos a manipulação estatística. A «Notícias da Biblioteca», uma newsletter publicada bimestralmente pela Biblioteca FCUP, inclui uma seção denominada “Voz do Utilizador”, onde são incluídos pequenos textos de opinião da autoria dos utilizadores, escolhidos aleatoriamente e, que frequentam as instalações destes serviços da FCUP. Aplicando a Norma Internacional ISO16439:2014 (E) – Information and documentation – Methods and procedures for assessing the impact of libraries, examinaram-se vinte textos de opinião, sobre a biblioteca, redigidos por estudantes de várias nacionalidades, publicados de janeiro de 2013 a dezembro de 2014, na «Notícias da Biblioteca». Investigaram-se ainda 7 entrevistas. Apelando à Estatística Descritiva efetuaram-se tabelas de contingência que são úteis para conhecer a relação entre os dados em função de determinados grupos, isto é, observar a frequência de uma variável em função das categorias de outra variável. Com as tabelas de contingência obtém-se percentagens em função dos efeitos do impacto da biblioteca e dos grupos de estudantes e analisa-se a relação entre eles. O estudo utilizou ainda alguns dados estatísticos indicadores que mostram o impacto, a saber, indicadores de desempenho relativos ao uso da biblioteca – número de visitas per capita e número de empréstimos per capita. Estas avaliações em bibliotecas fornecem informações úteis para as chefias de topo, para o desenvolvimento de novos projetos e a otimização do impacto e desempenho destes serviços das instituições de Ensino Superior./ This study presents an impact assessment of the Library of the Faculty of Science, University of Porto (FCUP), from the students’ point of view and some statistical data collected from the FCUP Library use. We used a mixed methods research, i.e., qualitative data, that describes but does not measure characteristics, in particular human actions, and quantitative data represented by numbers that indicate exact amounts which can be statistically manipulated. The newsletter «Notícias da Biblioteca» published, bimonthly, by the FCUP Library includes a section called “User Voice” where we can find opinion texts expressed by library users, randomly chosen, and who usually go to the library. Applying International Standard ISO16439: 2014 (E) - Information and documentation - Methods and procedures for assessing the impact of libraries, we examined 20 opinion texts written by students of various nationalities, published from January 2013 to December 2014, in «Notícias da Biblioteca» During this period of time, we have taken seven interviews. Using the principles of Descriptive Statistics, we produced Contingency Tables to determine how the data relates in terms of certain groups, i.e., to observe the frequency of the dependent variable on another categorical variable. Working with the Contingency Tables allowed us to obtain percentages according to the effects of the impact of the library in various groups of students and study the relationship between them. This study also used some statistical data that show the impact of the library within the institution, such as: performance indicators relating to the use of the library - number of visits per capita and number of loans per capita. These assessment impact studies in libraries provide useful data for the top management, to develop new projects, thus maximizing the impact and performance of these services of higher education institutions.

Expenditure pattern analysis of cultural tourists at World Heritage Sites: an empirical evidence based on CHAID analysis

Nowadays, World Heritage Sites (WHS) have been facing new challenges, partially due to a different tourism consumption patterns. As it is highlighted in a considerable amount of studies, visits to these sites are almost justified by this prestigious classification and motivations are closely associated with their cultural aspects and quality of the overall environment (among others, Marujo et al, 2012). However, a diversity of tourists’ profiles have been underlined in the literature. Starting from the results obtained in a previous study about cultural tourists’ profile, conducted during the year 2009 in the city of Évora, Portugal, it is our intend to compare the results with a recent survey applied to the visitors of the same city. Recognition of Évora by UNESCO in 1986 as “World Heritage” has fostered not only the preservation of heritage but also the tourist promotion of the town. This study compares and examined tourists’ profile, regarding from the tourists’ expenditure patterns in Évora. A total of 450 surveys were distributed in 2009, and recently, in 2015, the same numbers of surveys were collected. Chi-squared Automatic Interaction Detection (CHAID) was applied to model consumer patterns of domestic and international visitors, based on socio demographic, trip characteristics, length of stay and the degree of satisfaction of pull factors. CHAID allowed find a population classification in groups that able to describe the dependent variable, average daily tourist expenditure. Results revealed different patterns of daily average expenditure amongst the years, 2009 and 2015, even if primarily results not revealed significant variations in socio-demographic and trip characteristics among the visitors’ core profile. Local authorities should be aware of this changing expensive behavior of cultural visitors and should formulate strategies accordingly. Policy and managerial recommendations are discussed.

Motivação e satisfação no trabalho: aplicação numa organização do setor de formação profissional

Os recursos humanos são considerados o ativo mais poderoso e valioso de qualquer organização, mas o seu desempenho é, de uma forma geral, influenciado pela motivação e satisfação no trabalho. Deste modo, a presente investigação pretende analisar a motivação e a satisfação dos colaboradores numa organização do sector da formação profissional. A partir deste pressuposto, pretende-se analisar a motivação e a satisfação dos colaboradores da instituição alvo do estudo, averiguar se se verifica correlação entre as vaiáveis motivacionais (sucesso, afiliação e poder) e as variáveis de satisfação (salário, promoções, colegas de trabalho, superiores hierárquicos e realização da tarefa), analisar o relacionamento entre a variável dependente (satisfação com o salário) e variáveis independentes de natureza sociodemográfica e analisar se a motivação e a satisfação global dos colaboradores são influenciadas pelas variáveis explicativas da análise fatorial de componentes principais. A análise dos dados baseou-se em 72 inquéritos por questionário que foram já validados por autores da motivação (McClelland) e satisfação (Deshpande), aplicados à totalidade dos colaboradores da empresa, ou seja, à população em estudo. Procedeu-se à análise estatística para sustentar toda a parte empírica. Os resultados mostram que os colaboradores da empresa Competir se sentem razoavelmente motivados e satisfeitos, ainda que um pouco mais motivados do que satisfeitos. Concluiu-se que, na generalidade, os colaboradores se sentem motivados essencialmente no que diz respeito ao sucesso e afiliação, e satisfeitos principalmente com os seus colegas de trabalho e com a realização da tarefa. A satisfação com o salário é mais baixa no caso de género feminino, mas tende a aumentar com a antiguidade na empresa; Motivation and Job Satisfaction: An Application in an organization of vocational training sector Abstract: Human resources are considered the most powerful and valuable asset in any organization, but its performance is, in general, influenced by motivation and job satisfaction. The present research intends to analyse the motivation and the satisfaction of the employees in an organization of vocational training sector. Based on this assumption, we intend to analyze the motivation and satisfaction of the employees of the studied institution, to verify if there is a correlation between motivational (success, affiliation and power) and satisfaction variables (salary, promotions, Work, hierarchical superiors and task accomplishment), to analyze the relationship between the dependent variable (satisfaction with the salary) and independent variables of a sociodemographic nature and to analyze if the motivation and the overall satisfaction of the employees are influenced by the explanatory variables of the principal components factorial analysis. Data analysis was based on 72 questionnaire surveys that have already been validated by the authors of motivation (McClelland) and satisfaction (Deshpande), applied to all the company's employees, i.e., the study population. In order to support all the empirical part, were proceeded to the statistical analysis. The results shows that the employees of the company Competir feel reasonably motivated and satisfied, even if a little more motivated than satisfied. It was concluded that, in general, employees feel motivated primarily with regard to success and affiliation, and especially satisfied with their co-workers and with the complete of the task. Satisfaction with salary it’s lower in the case of female gender, but tends to increase with seniority in the company.

Limited Ca(2+) and PKA-pathway dependent neurogenic differentiation of human adult mesenchymal stem cells as compared to fetal neuronal stem cells

The ability of mesenchymal stem cells to generate functional neurons in culture is still a matter of controversy. In order to assess this issue, we performed a functional comparison between neuronal differentiation of human MSCs and fetal-derived neural stem cells (NSCs) based on morphological, immunocytochemical, and electrophysiological criteria. Furthermore, possible biochemical mechanisms involved in this process were presented. NF200 immunostaining was used to quantify the yield of differentiated cells after exposure to CAMP. The addition of a PKA inhibitor and Ca(2+) blockers to the differentiation medium significantly reduced the yield of differentiated cells. Activation of CREB was also observed on MSCs during maturation. Na(+)-, K(+)-, and Ca(2+)-voltage-dependent currents were recorded from MSCs-derived cells. In contrast, significantly larger Na(+) currents, firing activity, and spontaneous synaptic currents were recorded from NSCs. Our results indicate that the initial neuronal differentiation of MSCs is induced by CAMP and seems to be dependent upon Ca(2+) and the PKA pathway. However, compared to fetal neural stem cells, adult mesenchymal counterparts are limited in their neurogenic potential. Despite the similar yield of neuronal cells, NSCs achieved a more mature functional state. Description of the underlying mechanisms that govern MSCs` differentiation toward a stable neuronal phenotype and their limitations provides a unique opportunity to enhance our understanding of stem cell plasticity. (C) 2009 Elsevier Inc. All rights reserved.

Coronary artery disease, microalbuminuria and lipid profile in patients with non-insulin dependent diabetes mellitus

PURPOSE: To determine the frequency of coronary artery disease, microalbuminuria and the relation to lipid profile disorders, blood pressure and clinical and metabolic features. METHODS: Fifty-five type 2 diabetic patients (32 females, 23 males), aged 59.9±9 years and with known diabetes duration of 11±7.3 years were studied. Coronary artery disease (CAD) was defined as a positive history of myocardial infarction, typical angina, myocardial revascularization or a positive stress testing. Microalbuminuria was defined when two out of three overnight urine samples had a urinary albumin excretion ranging 20 - 200µg/min. RESULTS: CAD was present in 24 patients (43,6%). High blood pressure (HBP) present in 32 patients (58.2%) and was more frequent in CAD group (p=0.05) HBP. Increased the risk of CAD 3.7 times (CI[1.14-12]). Microalbuminuria was present in 25 patients (45.5%) and tended to associate with higher systolic blood pressure (SBP) (p = 0.06), presence of hypertension (p = 0.06) and know diabetes duration (p = 0.08). In the stepwise multiple logistic regression the systolic blood pressure was the only variable that influenced UAE (r = 0.39, r² = 0.14, p = 0.01). The h ypertensive patients had higher cholesterol levels (p = 0.04). CONCLUSION: In our sample the frequency of microalbuminuria, hypertension, hypercholesterolemia and CHD was high. Since diabetes is an independent risk factor for cardiovascular disease, the association of others risk factors suggest the need for an intensive therapeutic intervention in primary and in secundary prevention.

Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer.

BACKGROUND: The mutation status of the BRAF and KRAS genes has been proposed as prognostic biomarker in colorectal cancer. Of them, only the BRAF V600E mutation has been validated independently as prognostic for overall survival and survival after relapse, while the prognostic value of KRAS mutation is still unclear. We investigated the prognostic value of BRAF and KRAS mutations in various contexts defined by stratifications of the patient population. METHODS: We retrospectively analyzed a cohort of patients with stage II and III colorectal cancer from the PETACC-3 clinical trial (N = 1,423), by assessing the prognostic value of the BRAF and KRAS mutations in subpopulations defined by all possible combinations of the following clinico-pathological variables: T stage, N stage, tumor site, tumor grade and microsatellite instability status. In each such subpopulation, the prognostic value was assessed by log rank test for three endpoints: overall survival, relapse-free survival, and survival after relapse. The significance level was set to 0.01 for Bonferroni-adjusted p-values, and a second threshold for a trend towards statistical significance was set at 0.05 for unadjusted p-values. The significance of the interactions was tested by Wald test, with significance level of 0.05. RESULTS: In stage II-III colorectal cancer, BRAF mutation was confirmed a marker of poor survival only in subpopulations involving microsatellite stable and left-sided tumors, with higher effects than in the whole population. There was no evidence for prognostic value in microsatellite instable or right-sided tumor groups. We found that BRAF was also prognostic for relapse-free survival in some subpopulations. We found no evidence that KRAS mutations had prognostic value, although a trend was observed in some stratifications. We also show evidence of heterogeneity in survival of patients with BRAF V600E mutation. CONCLUSIONS: The BRAF mutation represents an additional risk factor only in some subpopulations of colorectal cancers, in others having limited prognostic value. However, in the subpopulations where it is prognostic, it represents a marker of much higher risk than previously considered. KRAS mutation status does not seem to represent a strong prognostic variable.

The use of classification and regression trees to predict the likelihood of seasonal influenza.

Background Individual signs and symptoms are of limited value for the diagnosis of influenza. Objective To develop a decision tree for the diagnosis of influenza based on a classification and regression tree (CART) analysis. Methods Data from two previous similar cohort studies were assembled into a single dataset. The data were randomly divided into a development set (70%) and a validation set (30%). We used CART analysis to develop three models that maximize the number of patients who do not require diagnostic testing prior to treatment decisions. The validation set was used to evaluate overfitting of the model to the training set. Results Model 1 has seven terminal nodes based on temperature, the onset of symptoms and the presence of chills, cough and myalgia. Model 2 was a simpler tree with only two splits based on temperature and the presence of chills. Model 3 was developed with temperature as a dichotomous variable (≥38°C) and had only two splits based on the presence of fever and myalgia. The area under the receiver operating characteristic curves (AUROCC) for the development and validation sets, respectively, were 0.82 and 0.80 for Model 1, 0.75 and 0.76 for Model 2 and 0.76 and 0.77 for Model 3. Model 2 classified 67% of patients in the validation group into a high- or low-risk group compared with only 38% for Model 1 and 54% for Model 3. Conclusions A simple decision tree (Model 2) classified two-thirds of patients as low or high risk and had an AUROCC of 0.76. After further validation in an independent population, this CART model could support clinical decision making regarding influenza, with low-risk patients requiring no further evaluation for influenza and high-risk patients being candidates for empiric symptomatic or drug therapy.