Discrepancies in Outcome Reporting Exist Between Protocols and Published Oral Health Cochrane Systematic Reviews

OBJECTIVES To assess discrepancies in the analyzed outcomes between protocols and published reviews within Cochrane oral health systematic reviews (COHG) on the Cochrane Database of Systematic Reviews (CDSR). STUDY DESIGN AND SETTING All COHG systematic reviews on the CDSR and the corresponding protocols were retrieved in November 2014 and information on the reported outcomes was recorded. Data was collected at the systematic review level by two reviewers independently. RESULTS One hundred and fifty two reviews were included. In relation to primary outcomes, 11.2% were downgraded to secondary outcomes, 9.9% were omitted altogether in the final publication and new primary outcomes were identified in 18.4% of publications. For secondary outcomes, 2% were upgraded to primary, 12.5% were omitted and 30.9% were newly introduced in the publication. Overall, 45.4% of reviews had at least one discrepancy when compared to the protocol; these were reported in 14.5% reviews. The number of review updates appears to be associated with discrepancies between final review and protocol (OR: 3.18, 95% CI: 1.77, 5.74, p<0.001). The risk of reporting significant results was lower for both downgraded outcomes [RR: 0.52, 95% CI: 0.17, 1.58, p = 0.24] and upgraded or newly introduced outcomes [RR: 0.77, 95% CI: 0.36, 1.64, p = 0.50] compared to outcomes with no discrepancies. The risk of reporting significant results was higher for upgraded or newly introduced outcomes compared to downgraded outcomes (RR = 1.19, 95% CI: 0.65, 2.16, p = 0.57). None of the comparisons reached statistical significance. CONCLUSION While no evidence of selective outcome reporting was found in this study, based on the present analysis of SRs published within COHG systematic reviews, discrepancies between outcomes in pre-published protocols and final reviews continue to be common. Solutions such as the use of standardized outcomes to reduce the prevalence of this issue may need to be explored.

Dynamic Unicast: Information-Centric Multi-hop Routing for Mobile Ad-hoc Networks

Abstract Information-centric networking (ICN) offers new perspectives on mobile ad-hoc communication because routing is based on names but not on endpoint identifiers. Since every content object has a unique name and is signed, authentic content can be stored and cached by any node. If connectivity to a content source breaks, it is not necessarily required to build a new path to the same source but content can also be retrieved from a closer node that provides the same content copy. For example, in case of collisions, retransmissions do not need to be performed over the entire path but due to caching only over the link where the collision occurred. Furthermore, multiple requests can be aggregated to improve scalability of wireless multi-hop communication. In this work, we base our investigations on Content-Centric Networking (CCN), which is a popular {ICN} architecture. While related works in wireless {CCN} communication are based on broadcast communication exclusively, we show that this is not needed for efficient mobile ad-hoc communication. With Dynamic Unicast requesters can build unicast paths to content sources after they have been identified via broadcast. We have implemented Dynamic Unicast in CCNx, which provides a reference implementation of the {CCN} concepts, and performed extensive evaluations in diverse mobile scenarios using NS3-DCE, the direct code execution framework for the {NS3} network simulator. Our evaluations show that Dynamic Unicast can result in more efficient communication than broadcast communication, but still supports all {CCN} advantages such as caching, scalability and implicit content discovery.

Design of a systematic approach to workplace exposure medical surveillance protocols

Current toxic tort cases have increased national awareness of health concerns and present an important avenue in which public health scientists can perform a vital function: in litigation, and in public health initiatives and promotions which may result. This review presents a systematic approach, using the paradigm of interactive public health disciplines, for the design of a matrix framework for medical surveillance of workers exposed to toxic substances. The matrix framework design addresses the required scientific bases to support the legal remedy of medical monitoring for workers injured as a result of their exposure to toxic agents. A background of recent legal developments which have a direct impact on the use of scientific expertise in litigation is examined in the context of toxic exposure litigation and the attainment of public health goals. The matrix model is applied to five different workplace exposures: dental mercury, firefighting, vinyl chloride manufacture, radon in mining and silica. An exposure matrix designed by the Department of Energy for government nuclear workers is included as a reference comparison to the design matrix. ^

Contribución a los modelos de gestión de las redes móviles ad hoc

La capacidad de comunicación de los seres humanos ha crecido gracias a la evolución de dispositivos móviles cada vez más pequeños, manejables, potentes, de mayor autonomía y más asequibles. Esta tendencia muestra que en un futuro próximo cercano cada persona llevaría consigo por lo menos un dispositivo de altas prestaciones. Estos dispositivos tienen incorporados algunas formas de comunicación: red de telefonía, redes inalámbricas, bluetooth, entre otras. Lo que les permite también ser empleados para la configuración de redes móviles Ad Hoc. Las redes móviles Ad Hoc, son redes temporales y autoconfigurables, no necesitan un punto de acceso para que los nodos intercambien información entre sí. Cada nodo realiza las tareas de encaminador cuando sea requerido. Los nodos se pueden mover, cambiando de ubicación a discreción. La autonomía de estos dispositivos depende de las estrategias de como sus recursos son utilizados. De tal forma que los protocolos, algoritmos o modelos deben ser diseñados de forma eficiente para no impactar el rendimiento del dispositivo, siempre buscando un equilibrio entre sobrecarga y usabilidad. Es importante definir una gestión adecuada de estas redes especialmente cuando estén siendo utilizados en escenarios críticos como los de emergencias, desastres naturales, conflictos bélicos. La presente tesis doctoral muestra una solución eficiente para la gestión de redes móviles Ad Hoc. La solución contempla dos componentes principales: la definición de un modelo de gestión para redes móviles de alta disponibilidad y la creación de un protocolo de enrutamiento jerárquico asociado al modelo. El modelo de gestión propuesto, denominado High Availability Management Ad Hoc Network (HAMAN), es definido en una estructura de cuatro niveles, acceso, distribución, inteligencia e infraestructura. Además se describen los componentes de cada nivel: tipos de nodos, protocolos y funcionamiento. Se estudian también las interfaces de comunicación entre cada componente y la relación de estas con los niveles definidos. Como parte del modelo se diseña el protocolo de enrutamiento Ad Hoc, denominado Backup Cluster Head Protocol (BCHP), que utiliza como estrategia de encaminamiento el empleo de cluster y jerarquías. Cada cluster tiene un Jefe de Cluster que concentra la información de enrutamiento y de gestión y la envía al destino cuando esta fuera de su área de cobertura. Para mejorar la disponibilidad de la red el protocolo utiliza un Jefe de Cluster de Respaldo el que asume las funciones del nodo principal del cluster cuando este tiene un problema. El modelo HAMAN es validado a través de un proceso la simulación del protocolo BCHP. El protocolo BCHP se implementa en la herramienta Network Simulator 2 (NS2) para ser simulado, comparado y contrastado con el protocolo de enrutamiento jerárquico Cluster Based Routing Protocol (CBRP) y con el protocolo de enrutamiento Ad Hoc reactivo denominado Ad Hoc On Demand Distance Vector Routing (AODV). Abstract The communication skills of humans has grown thanks to the evolution of mobile devices become smaller, manageable, powerful, more autonomy and more affordable. This trend shows that in the near future each person will carry at least one high-performance device. These high-performance devices have some forms of communication incorporated: telephony network, wireless networks, bluetooth, among others. What can also be used for configuring mobile Ad Hoc networks. Ad Hoc mobile networks, are temporary and self-configuring networks, do not need an access point for exchange information between their nodes. Each node performs the router tasks as required. The nodes can move, change location at will. The autonomy of these devices depends on the strategies of how its resources are used. So that the protocols, algorithms or models should be designed to efficiently without impacting device performance seeking a balance between overhead and usability. It is important to define appropriate management of these networks, especially when being used in critical scenarios such as emergencies, natural disasters, wars. The present research shows an efficient solution for managing mobile ad hoc networks. The solution comprises two main components: the definition of a management model for highly available mobile networks and the creation of a hierarchical routing protocol associated with the model. The proposed management model, called High Availability Management Ad Hoc Network (HAMAN) is defined in a four-level structure: access, distribution, intelligence and infrastructure. The components of each level: types of nodes, protocols, structure of a node are shown and detailed. It also explores the communication interfaces between each component and the relationship of these with the levels defined. The Ad Hoc routing protocol proposed, called Backup Cluster Head Protocol( BCHP), use of cluster and hierarchies like strategies. Each cluster has a cluster head which concentrates the routing information and management and sent to the destination when out of cluster coverage area. To improve the availability of the network protocol uses a Backup Cluster Head who assumes the functions of the node of the cluster when it has a problem. The HAMAN model is validated accross the simulation of their BCHP routing protocol. BCHP protocol has been implemented in the simulation tool Network Simulator 2 (NS2) to be simulated, compared and contrasted with a hierarchical routing protocol Cluster Based Routing Protocol (CBRP) and a routing protocol called Reactive Ad Hoc On Demand Distance Vector Routing (AODV).

A low power routing algorithm for localization in IEEE 802.15.4 networks

Many context-aware applications rely on the knowledge of the position of the user and the surrounding objects to provide advanced, personalized and real-time services. In wide-area deployments, a routing protocol is needed to collect the location information from distant nodes. In this paper, we propose a new source-initiated (on demand) routing protocol for location-aware applications in IEEE 802.15.4 wireless sensor networks. This protocol uses a low power MAC layer to maximize the lifetime of the network while maintaining the communication delay to a low value. Its performance is assessed through experimental tests that show a good trade-off between power consumption and time delay in the localization of a mobile device.

Desing of an Airport Surface Routing Evaluation Tool

There are many studies related with airport surface routing algorithms, based on different approaches and with different evaluation methods and metrics. So, the need of performing a balanced analysis and comparison using a common framework is evident. This paper presents an implementation of an evaluation tool for airport surface routing algorithms. The routing evaluation tool presented here is based in three basic pillars composed by the airport model, the model and generation of traffic and a comprehensive figure of merit function. The paper includes some example evaluations performed over Barajas Airport with representative traffic samples using several simple routing methods.

Fast measurement of cooling and heating rates in standard cryopreservation protocols based on vitrification

Estudio de la cinética de la crioconservación de tejidos vegetales

Improving availability of mobile networks using a cluster routing protocol with redundant cluster head

We show a cluster based routing protocol in order to improve the convergence of the clusters and of the network it is proposed to use a backup cluster head. The use of a event discrete simulator is used for the implementation and the simulation of a hierarchical routing protocol called the Backup Cluster Head Protocol (BCHP). Finally it is shown that the BCHP protocol improves the convergence and availability of the network through a comparative analysis with the Ad Hoc On Demand Distance Vector (AODV)[1] routing protocol and Cluster Based Routing Protocol (CBRP)[2]

Temperature Sensor Placement Including Routing Overhead and Sampling Inaccuracies

Dynamic thermal management techniques require a collection of on-chip thermal sensors that imply a significant area and power overhead. Finding the optimum number of temperature monitors and their location on the chip surface to optimize accuracy is an NP-hard problem. In this work we improve the modeling of the problem by including area, power and networking constraints along with the consideration of three inaccuracy terms: spatial errors, sampling rate errors and monitor-inherent errors. The problem is solved by the simulated annealing algorithm. We apply the algorithm to a test case employing three different types of monitors to highlight the importance of the different metrics. Finally we present a case study of the Alpha 21364 processor under two different constraint scenarios.

Automatic Generation of Identical Routing Pairs for FPGA Implemented DPL Logic

Side Channel Attacks (SCAs) typically gather unintentional (side channel) physical leakages from running crypto-devices to reveal confidential data. Dual-rail Precharge Logic (DPL) is one of the most efficient countermeasures against power or EM side channel threats. This logic relies on the implementation of complementary rails to counterbalance the data-dependent variations of the leakage from dynamic behavior of the original circuit. However, the lack of flexibility of commercial FPGA design tools makes it quite difficult to obtain completely balanced routings between complementary networks. In this paper, a controllable repair mechanism to guarantee identical net pairs from two lines is presented: i. repairs the identical yet conflict nets after the duplication (copy & paste) from original rail to complementary rail, and ii. repairs the non-identical nets in off-the-stock DPL circuits; These rerouting steps are carried out starting from a placed and routed netlist using Xilinx Description Language (XDL). Low level XDL modifications have been completely automated using a set of APIs named RapidSmith. Experimental EM attacks show that the resistance level of an AES core after the automatic routing repair is increased in a factor of at least 3.5. Timing analyses further demonstrate that net delay differences between complementary networks are minimized significantly.

Desarrollo de aplicaciones de comunicaciones inalámbricas en sistemas de monitorización estructural desarrollados en aeronáutica.

Los Sistemas de SHM o de monitorización de la integridad estructural surgen ante la necesidad de mejorar los métodos de evaluación y de test no destructivos convencionales. De esta manera, se puede tener controlado todo tipo de estructuras en las cuales su correcto estado o funcionamiento suponga un factor crítico. Un Sistema SHM permite analizar una estructura concreta capturando de manera periódica el estado de la integridad estructural, que en este proyecto se ha aplicado a estructuras aeronáuticas. P.A.M.E.L.A. (Phase Array Monitoring for Enhanced Life Assessment) es la denominación utilizada para definir una serie de equipos electrónicos para Sistemas SHM desarrollados por AERNOVA y los Grupos de Diseño Electrónico de las universidades UPV/EHU y UPM. Los dispositivos P.A.M.E.L.A. originalmente no cuentan con tecnología Wi-Fi, por lo que incorporan un módulo hardware independiente que se encarga de las comunicaciones inalámbricas, a los que se les denomina Nodos. Estos Nodos poseen un Sistema Operativo propio y todo lo necesario para administrar y organizar la red Mallada Wi-Fi. De esta manera se obtiene una red mallada inalámbrica compuesta por Nodos que interconectan los Sistemas SHM y que se encargan de transmitir los datos a los equipos que procesan los resultados adquiridos por P.A.M.E.L.A. Los Nodos son dispositivos empotrados que llevan instalados un firmware basado en una distribución de Linux para Nodos (o Routers), llamado Openwrt. Que para disponer de una red mallada necesitan de un protocolo orientado a este tipo de redes. Entre las opciones de protocolo más destacadas se puede mencionar: DSDV (Destination Sequenced Distance Vector), OLSR (Optimized Link State Routing), B.A.T.M.A.N-Adv (Better Approach To Mobile Adhoc Networking Advance), BMX (una versión de B.A.T.M.A.N-Adv), AODV (Ad hoc On-Demand Distance Vector) y el DSR (Dynamic Source Routing). Además de la existencia de protocolos orientados a las redes malladas, también hay organizaciones que se dedican a desarrollar firmware que los utilizan, como es el caso del firmware llamado Nightwing que utiliza BMX, Freifunk que utiliza OLSR o Potato Mesh que utiliza B.A.T.M.A.N-Adv. La ventaja de estos tres firmwares mencionados es que las agrupaciones que las desarrollan proporcionan las imágenes precompiladas del sistema,listas para cargarlas en distintos modelos de Nodos. En este proyecto se han instalado las imágenes en los Nodos y se han probado los protocolos BMX, OLSR y B.A.T.M.A.N.-Adv. Concluyendo que la red gestionada por B.A.T.M.A.N.-Adv era la que mejor rendimiento obtenía en cuanto a estabilidad y ancho de banda. Después de haber definido el protocolo a usar, se procedió a desarrollar una distribución basada en Openwrt, que utilice B.A.T.M.A.N.-Adv para crear la red mallada, pero que se ajuste mejor a las necesidades del proyecto, ya que Nightwing, Freifunk y Potato Mesh no lo hacían. Además se implementan aplicaciones en lenguaje ANSI C y en LabVIEW para interactuar con los Nodos y los Sistemas SHM. También se procede a hacer alguna modificación en el Hardware de P.A.M.E.L.A. y del Nodo para obtener una mejor integración entre los dos dispositivos. Y por ultimo, se prueba la transferencia de datos de los Nodos en distintos escenarios. ABSTRACT. Structural Health Monitoring (SHM) systems arise from the need of improving assessment methods and conventional nondestructive tests. Critical structures can be monitored using SHM. A SHM system analyzes periodically a specific structure capturing the state of structural integrity. The aim of this project is to contribute in the implementation of Mesh network for SHM system in aircraft structures. P.A.M.E.L.A. (Phase Array Monitoring for Enhanced Life Assessment) is the name for electronic equipment developed by AERNOVA, the Electronic Design Groups of university UPV/EHU and the Instrumentation and Applied Acoustics research group from UPM. P.A.M.E.L.A. devices were not originally equipped with Wi-Fi interface. In this project a separate hardware module that handles wireless communications (nodes) has been added. The nodes include an operating system for manage the Wi-Fi Mesh Network and they form the wireless mesh network to link SHM systems with monitoring equipment. Nodes are embedded devices with an installed firmware based on special Linux distribution used in routers or nodes, called OpenWRT. They need a Mesh Protocol to stablish the network. The most common protocols options are: DSDV (Destination Sequenced Distance Vector), OLSR (Optimized Link State Routing), BATMAN-Adv (Better Approach To Mobile Ad-hoc Networking Advance), BMX (a version of BATMAN-Adv) AODV (Ad hoc on-Demand Distance Vector) and DSR (Dynamic Source Routing). In addition, there are organizations that are dedicated to develope firmware using these Mesh Protocols, for instance: Nightwing uses BMX, Freifunk use OLSR and Potato Mesh uses BATMAN-Adv. The advantage of these three firmwares is that these groups develop pre-compiled images of the system ready to be loaded in several models of Nodes. In this project the images were installed in the nodes. In this way, BMX, OLSR and BATMAN-Adv have been tested. We conclude that the protocol BATMAN-Adv has better performance in terms of stability and bandwidth. After choosing the protocol, the objective was to develop a distribution based on OpenWRT, using BATMAN-Adv to create the mesh network. This distribution is fitted to the requirements of this project. Besides, in this project it has been developed applications in C language and LabVIEW to interact with the Nodes and the SHM systems. The project also address some modifications to the PAMELA hardware and the Node, for better integration between both elements. Finally, data transfer tests among the different nodes in different scenarios has been carried out.

A bivariate return period based on copulas for hydrologic dam design: accounting for reservoir routing in risk estimation

A multivariate analysis on flood variables is needed to design some hydraulic structures like dams, as the complexity of the routing process in a reservoir requires a representation of the full hydrograph. In this work, a bivariate copula model was used to obtain the bivariate joint distribution of flood peak and volume, in order to know the probability of occurrence of a given inflow hydrograph. However, the risk of dam overtopping is given by the maximum water elevation reached during the routing process, which depends on the hydrograph variables, the reservoir volume and the spillway crest length. Consequently, an additional bivariate return period, the so-called routed return period, was defined in terms of risk of dam overtopping based on this maximum water elevation obtained after routing the inflow hydrographs. The theoretical return periods, which give the probability of occurrence of a hydrograph prior to accounting for the reservoir routing, were compared with the routed return period, as in both cases hydrographs with the same probability will draw a curve in the peak-volume space. The procedure was applied to the case study of the Santillana reservoir in Spain. Different reservoir volumes and spillway lengths were considered to investigate the influence of the dam and reservoir characteristics on the results. The methodology improves the estimation of the Design Flood Hydrograph and can be applied to assess the risk of dam overtopping

Sophisticated security verification on routing repaired balanced cell-based dual-rail logic against side channel analysis

Conventional dual-rail precharge logic suffers from difficult implementations of dual-rail structure for obtaining strict compensation between the counterpart rails. As a light-weight and high-speed dual-rail style, balanced cell-based dual-rail logic (BCDL) uses synchronised compound gates with global precharge signal to provide high resistance against differential power or electromagnetic analyses. BCDL can be realised from generic field programmable gate array (FPGA) design flows with constraints. However, routings still exist as concerns because of the deficient flexibility on routing control, which unfavourably results in bias between complementary nets in security-sensitive parts. In this article, based on a routing repair technique, novel verifications towards routing effect are presented. An 8 bit simplified advanced encryption processing (AES)-co-processor is executed that is constructed on block random access memory (RAM)-based BCDL in Xilinx Virtex-5 FPGAs. Since imbalanced routing are major defects in BCDL, the authors can rule out other influences and fairly quantify the security variants. A series of asymptotic correlation electromagnetic (EM) analyses are launched towards a group of circuits with consecutive routing schemes to be able to verify routing impact on side channel analyses. After repairing the non-identical routings, Mutual information analyses are executed to further validate the concrete security increase obtained from identical routing pairs in BCDL.

Análisis de prestaciones y eficiencia de tablas de cobertura para CBR (Content-Based Routing)

Hoy en día, los sistemas middleware de publicar-suscribir con la filtración de mensajes basado en contenido tiende a ser popularizado, y un sistema como este requiere codificar su mensaje a la combinación de varios elementos que se encuentran en los conjuntos no-interseccionados. Varios predicados posibles en los dominios de esos conjuntos forman un filtro, y el núcleo de algoritmo filtrado es seleccionar filtros adaptados tan pronto como sea posible. Sin embargo, el conjunto, que está formado por los filtros, contiene la extremadamente fuerte indeterminación y distensibilidad, lo que restringe el algoritmo filtrado. Por la resolución de la distensibilidad, se estudió la característica del conjunto de filtros en álgebra, y sabía que es un retículo específico. Por lo tanto, se intenta usar el carácter, el cual los retículos forman un conjunto parcialmente ordenado (o poset, del inglés partially ordered set) con límites, para reducir el tamaño de conjunto de filtros (compresión equivalente). Por estas razones, es necesario implementar un contenedor abstracto de retículo, y evaluar su desempeño tanto en la teoría, como en la práctica, para la solución de la distensibilidad del conjunto de filtros. Retículo (Lattice) es una estructura importante de Álgebra Abstracta, comúnmente se utiliza para resolver el problema teórico, y apenas de ser un contenedor abstracto en la ciencia de software, como resultado de su implementación compleja que proviene de su trivialidad en álgebra. Y por eso se hace difícil mi trabajo. Con el fin de evitar la teoría compleja del sistema práctico, simplemente introduce su núcleo algoritmo, el algoritmo de conteo, y esto llevó a cabo con el problema - la distensibilidad del conjunto de filtros. A continuación, se investigó la solución posible con retículos en la teoría, y se obtuvo el diseño de la implementación, normas para las pruebas xUnit y par´ametros para la evaluación. Por último, señalamos el entorno, el resultado, el análisis y la conclusión de la prueba de rendimiento.