Les faunes de coraux (Anthozoaires Scléractiniaires) de la façade atlantique française au Chattien et au Miocène

The study of new abundant coral crops and a systematic revision of the historie collections allow us to extend significantly the data about the Upper Oligocene and Miocene Scleractinia of the French atlantic basins. The SW and W-NW France faunas have been considered, and complete lists of the different defined taxa are presented. The general lines of the evolution of this group are specified, and linked to the paleoclimatic and paleobiogeographic changes.

Les Fables de La Fontaine au Monastère de S. Vicente de Fora - Etude d´in panneau d´azulejos

Congresso Internacional de História da Medicina (ISHM); 39º - p.217-218

Henri Tintant face au problème "Science et Foi"

From an early age Henri Tintant was conforted with the problematic relationships between Science and Faith. After a traditional religious education, he took responsabilities within groups of teenagers and adults through scouting and the J. E. C. (an organisation of catholic students). In 1940 he was at Montpellier distributing unauthorised leaflets defending religious faith. But more significant is his intellectual contribution. He was an active and inspiring member of several workshops and in one in particumar initiated by the Catholic University of Lyon entitled : "From Naturalist to Theologians" where he would start a very fruitful and compelling intellectual collaboration with Father Gustave Martelet a jesuit theologian and a strong supporter of a permanent dialog with the scientists. Throughout the years they will gradually come to the conclusion of a necessary synergy between the scientific and the theologic approach when dealing with the mystery of religious faith . Even in the last months of his life, Henri Tintant was writing to his friendon the subject, with the same profound religious faith that brought him the serenity and the open mindness he has showed throughout his teaching and scientific career. His legacy will remain in two of his last thoughts: "Almost 50 years of scientific research have brought me a lot of pleausures and satisfactions but no answer to the essential questions. In my personal case, science and researching have not driven me away from my religious faith, on the contrary the helped me in my awareness of its utmost necessity". "Faithful to my religious belief, I am convinced that with the death, the inevitable human destiny, not everything disapears completely but another form of live, unimaginable for our limited minds, emerges, bearing in itself the perfect realization of all our hopes and desires".

Les enjeux de la construction de la politique d'immigration au Portugal

Comunicação apresentada no Congresso Internacional do IIAS, realizado em Lausanne, Suiça, de 4 a 8 de Julho de 2011.

Au-nanossondas aplicação na detecção de Mycobacterium tuberculosis e plasmodium berghei

Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para a obtenção do grau de Mestre em Biotecnologia

Novel biosensing device for point-of-care applications with plastic antibodies grown on Au-Screen Printed Electrodes

A gold screen printed electrode (Au-SPE) was modified by merging Molecular Imprinting and Self-Assembly Monolayer techniques for fast screening cardiac biomarkers in point-of-care (POC). For this purpose, Myoglobin (Myo) was selected as target analyte and its plastic antibody imprinted over a glutaraldehyde (Glu)/cysteamine (Cys) layer on the gold-surface. The imprinting effect was produced by growing a reticulated polymer of acrylamide (AAM) and N,N′-methylenebisacrylamide (NNMBA) around the Myo template, covalently attached to the biosensing surface. Electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) studies were carried out in all chemical modification steps to confirm the surface changes in the Au-SPE. The analytical features of the resulting biosensor were studied by different electrochemical techniques, including EIS, square wave voltammetry (SWV) and potentiometry. The limits of detection ranged from 0.13 to 8 μg/mL. Only potentiometry assays showed limits of detection including the cut-off Myo levels. Quantitative information was also produced for Myo concentrations ≥0.2 μg/mL. The linear response of the biosensing device showed an anionic slope of ~70 mV per decade molar concentration up to 0.3 μg/mL. The interference of coexisting species was tested and good selectivity was observed. The biosensor was successfully applied to biological fluids.

Le pouvoir royal et les villes portugaises au Moyen Age

pp. 15-28

3D-nanostructured Au electrodes for the event-specific detection of MON810 transgenic maize

In the present work, the development of a genosensor for the event-specific detection of MON810 transgenic maize is proposed. Taking advantage of nanostructuration, a cost-effective three dimensional electrode was fabricated and a ternary monolayer containing a dithiol, a monothiol and the thiolated capture probe was optimized to minimize the unspecific signals. A sandwich format assay was selected as a way of precluding inefficient hybridization associated with stable secondary target structures. A comparison between the analytical performance of the Au nanostructured electrodes and commercially available screen-printed electrodes highlighted the superior performance of the nanostructured ones. Finally, the genosensor was effectively applied to detect the transgenic sequence in real samples, showing its potential for future quantitative analysis.

“Green Electrodes” Modified with Au Nanoparticles Synthesized in Glycerol, as Electrochemical Nitrite Sensor

A new environmentally friendly Au nanoparticles (Au NPs) synthesis in glycerol by using ultraviolet irradiation and without extra-added stabilizers is described. The synthesis proposed in this work may impact on the non-polluting production of noble nanoparticles with simple chemicals normally found in standard laboratories. These Au NPs were used to modify a carbon paste electrode (CPE) without having to separate them from the reaction medium. This green electrode was used as an electrochemical sensor for the nitrite detection in water. At the optimum conditions the green sensor presented a linear response in the 2.0×10−7–1.5×10−5 M concentration range, a good detection sensitivity (0.268 A L mol−1), and a low detection limit of 2.0×10−7 M of nitrite. The proposed modified green CPE was used to determine nitrite in tap water samples.

Double regard sur les mémoires et pratiques alimentaires à Arez (Nordeste ede l’Alto Alentejo) et à Lannéanou (Nord du Finistère)Manques, âges d’or, aisances et abondances

Doctorat en sociologie

Promoção da saúde mental em espaço urbano

RESUMO: A saúde pública deve estar atenta aos contextos e às mudanças sociais, políticas, económicas, científicas e tecnológicas com que se confrontam constantemente as comunidades, particularmente em situações de grandes transformações como o momento que a União Europeia atravessa. A urbanização é provavelmente a mudança demográfica mais importante das últimas décadas. Tendo importantes repercussões sobre a saúde mental, é importante desenvolver a investigação neste domínio, de forma multidisciplinar e integrando a compreensão dos diferentes determinantes sociais, psicológicos e físicos. As políticas de saúde mental tornaram-se uma parte importante da política social e da sociedade de bem-estar, em particular se considerarmos a urbanização das nossas comunidades. Considerar a saúde mental em espaço urbano é fundamentalmente estudar como um espaço particular pode influenciar a saúde. Baseado nesta reflexão, desenvolveu-se uma investigação participada de base comunitária, com recurso a uma metodologia de estudo de caso. Recorreu-se a dezenas de documentos de referência local, registos em arquivo, à observação direta, à observação participante e à observação in loco do espaço urbano. Foi utilizada uma amostragem em bola de neve, estratificada, para selecionar 697 habitantes de uma cidade da área metropolitana de Lisboa. Estes habitantes foram entrevistados por 42 entrevistadores, previamente formados, assim como foram enviados questionários online dirigidos aos professores (196) e aos Técnicos Superiores de Serviço Social (12) em exercício no espaço urbano em estudo, para a caraterização sociodemográfica e para avaliação de indicadores de saúde, de indicadores relacionados com a saúde e de indicadores estruturais de saúde mental. Os resultados mostraram um espaço urbano promotor de saúde estrutura-se para capacitar os seus cidadãos a se integrarem ativamente no funcionamento da sua comunidade. Foram identificadas algumas caraterísticas como 1) o início do processo de promoção da saúde mental ser o mais precoce possível; 2) a participação comunitária ativa, num sentimento de segurança individual e comunitária, envolvendo estruturas governamentais e não-governamentais; 3) a solidariedade e a inclusão, promovendo o voluntariado e a promoção do suporte social e desenvolvendo a coesão social; 4) o reconhecimento das necessidades expressas pelos habitantes; 5) a identificação de respostas para a conciliação entre vida pessoal, familiar e profissional; 6) as estruturas de acompanhamento dos grupos sociais mais desfavorecidos; 7) as estratégias de combate ao isolamento envolvendo a população sénior e outros grupos minoritários ativamente no processo de reorganização do seu funcionamento social; 8) uma efetiva governança e gestão relacional por parte dos poderes locais, centrando a vida quotidiana da comunidade nas pessoas. A investigação participada de base comunitária constitui um instrumento útil e eficaz no desenho de planos locais de promoção da saúde mental para encontrar respostas ao desafio em saúde pública: a saúde mental e a urbanização.

Liver function evaluation in leptospirosis with colloidal gold 1 9 8 Au

Eight patients with leptospirosis were studied with colloidal gold 1 9 8 Au. The radiocolloidal hepatic distribution was altered, presenting a non-homogeneous tiver concentration in seven cases, and a minute to moderate splenic visualization in five. Two patients presented doubtful splenic image, and one seemed to be normal. Liver scanning with colloidal gold 1 9 8 Au is demonstra ted to be a good liver function test.

Efeito de um composto organometálico de Au(III) na actividade da aquagliceroporina-3

Dissertação para obtenção do Grau de Mestre em Bioquímica Estrutural e Funcional

Les enquêtes royales au Portugal, 1220-1343

Actes du colloque international d' Aix-en-Provence et Marseille, 19-21 mars 2009