Regulatory governance of ‘training markets’, ‘market failure’, and ‘quasi’ markets: historical dimensions of the post-initial training market in the Netherlands

This article examines regulatory governance of the post-initial training market in The Netherlands. From an historical perspective on policy formation processes, it examines market formation in terms of social, economic, and cultural factors in the development of provision and demand for post-initial training; the roles of stakeholders in the longterm construction of regulatory governance of the market; regulation of and public providers; policy responses to market failure; and tripartite division of responsibilities between the state, social partners, commercial and publicly-funded providers. Historical description and analysis examine policy narratives of key stakeholders with reference to: a) influence of societal stakeholders on regulatory decision-making; b) state regulation of the post-initial training market; c) public intervention regulating the market to prevent market failure; d) market deregulation, competition, employability and individual responsibility; and, e) regulatory governance to prevent ‘allocative failure’ by the market in non-delivery of post-initial training to specific target groups, particularly the low-qualified. Dominant policy narratives have resulted in limited state regulation of the supply-side, a tripartite system of regulatory governance by the state, social partners and commercial providers as regulatory actors. Current policy discourses address interventions on the demand-side to redistribute structures of opportunity throughout the life courses of individuals. Further empirical research from a comparative historical perspective is required to deepen contemporary understandings of regulatory governance of markets and the commodification of adult learning in knowledge societies and information economies. (DIPF/Orig.)

Saúde e bem-estar na empresa Boa Vista Golf & Spa Resort. Implementação de um plano de bem-estar

Dissertação de Mestrado, Gestão de Recursos Humanos, Escola Superior de Gestão, Hotelaria e Turismo, Faculdade de Ciências Humanas e Sociais, Universidade do Algarve, 2016

Desafios e perspectivas para institucionalização do monitoramento e avaliação no âmbito da gestão do Sistema Único de Saúde

Tese (doutorado)—Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Ciências da Saúde, 2016.

Structural and functional interaction between polyamine related molecules and biological membranes

Changes induced by PA on nucleic acid (NA) conformation and synthesis is proven to be a major reason for PA essentiality (1-3). However, PA interactions with other polyanions, for instance polyanionic membrane lipid bilayers and glyosaminoglycans have received less attention (3-4). The functional importance of these interactions still is an obscure but interesting area of cell and molecular biology, especially in mammalian cells for which specific PA transport systems are not fully characterized (5). In mammals, activity and turnover of the polyamine (PA) synthesis key enzyme is controlled by a set of proteins: Antizymes (OAZ1-3) and antizyme inhibitors (AZIN1 and 2). It is demonstrated that AOZ modulate polyamine uptake (6), and that PA transport to mitochondria is linked to the respiratory chain state and modulates mitochondrial permeability transition (7). Antizyme expression variants have been located in mitochondria, being proposed as a proapoptotic factor (7-8). AZIN 2 is only expressed in a reduced set of tissues that includes mast cells, where it is associated to mast cell granules membrane (9). This fact, together to the abnormalities observed in bone marrow derived mast cell granules when they are differentiated under restricted PA synthesis conditions (10 and unpublished results), point out to important roles of PA and their related proteins in structure and function of mast cell granules. We will also present novel biophysical results on tripartite interactions of PA that remark the interest of the characterization of PA interactions with lipid bilayers for biomedicine and biotechnology. Thus, the information reported in this paper integrates previously reported information with our still unpublished results, all indicating that PA and their related proteins also are important factors for structure and dynamics of biological membranes and their associated functions essential in human physiology; for instance, solute interchange with the environment (uptake and secretion), oxidative metabolism and apoptosis. The importance of these involved processes for human homeostasis claim for further research efforts. 1. Ruiz-Chica J, Medina MA, Sánchez-Jiménez F and Ramírez FJ (2001) Fourier Transform Raman study of the structural specificities on the interaction between DNA and biogenic polyamines. Biophysical J. 80:443-454. 2. Lightfoot HL, Hall J (2014) Endogenous polyamine function--the RNA perspective. Nucleic Acids Res. 42:11275-11290. 3. Igarashi K, Kashiwagi K (2010) Modulation of cellular function by polyamines. Int J Biochem Cell Biol. 42:39-51. 4. Finger S, Schwieger C, Arouri A, Kerth A, Blume A (2014) Interaction of linear polyamines with negatively charged phospholipids: the effect of polyamine charge distance. Biol Chem. 395:769-778. 5. Poulin R, Casero RA, Soulet D. (2012) Recent advances in the molecular biology of metazoan polyamine transport. Amino Acids. 42:711-723. 6. Kahana C (2009) Regulation of cellular polyamine levels and cellular proliferation by antizyme and antizyme inhibitor. Essays Biochem. 4:47-61. 7. Agostinelli E, Marques MP, Calheiros R, Gil FP, Tempera G, Viceconte N, Battaglia V, Grancara S, Toninello A (2010) Polyamines: fundamental characters in chemistry and biology. Amino Acids 38:393-403. 8. Liu GY, Liao YF, Hsu PC, Chang WH, Hsieh MC, Lin CY, Hour TC, Kao MC, Tsay GJ, Hung HC (2006) Antizyme, a natural ornithine decarboxylase inhibitor, induces apoptosis of haematopoietic cells through mitochondrial membrane depolarization and caspases' cascade. Apoptosis 11:1773-1788. 9. Kanerva K, Lappalainen J, Mäkitie LT, Virolainen S, Kovanen PT, Andersson LC (2009). Expression of antizyme inhibitor 2 in mast cells and role of polyamines as selective regulators of serotonin secretion. PLoS One 31:e6858. 10. García-Faroldi G, Rodríguez CE, Urdiales JL, Pérez-Pomares JM, Dávila JC, Pejler G, Sánchez-Jiménez F, Fajardo I (2010) Polyamines are present in mast cell secretory granules and are important for granule homeostasis. PLoS One 30:e15071.

La conservation autologue de sang de cordon ombilical : une ouverture sur une forme émergente de «citoyenneté biologique»

La transformation du sang de cordon ombilical en une précieuse source de cellules souches a, dès le début des années 1990, donné naissance à une industrie commerciale globale de conservation faisant désormais concurrence à un large réseau de conservation public. Ce mémoire cherche à comprendre et à expliquer les soubassements socio-culturels liés à l’émergence de cette industrie, ainsi qu’à mieux cerner les enjeux éthiques et politiques qu’elle pose. En exposant en premier lieu la manière dont les institutions publiques de conservation de sang de cordon se définissent, et sont généralement définies par les comités bioéthiques, comme étant porteuses des valeurs d’altruisme et de solidarité nationale traditionnellement liées au modèle « redistributif » d’échange de sang et d’organes né au lendemain de la Seconde Guerre mondiale, nous problématisons la manière innovatrice par laquelle les banques privées structurent le rapport entre les mères et leurs propres produits biologiques comme l’expression d’une reconfiguration du lien social et politique caractérisée par l’émergence de nouvelles socialisés. L’hypothèse au coeur de ce mémoire est que celles-ci peuvent être comprises comme l’aboutissant de l‘espoir collectivement partagé par les consommatrices d’améliorer leur propre condition biologique familiale, étant lui-même le fruit d’une financiarisation croissante des sciences du vivant. En analysant le discours « promissif » que représente le matériel promotionnel des banques autologues, notre objectif est alors d’identifier la manière par laquelle les multiples potentialités attribuées au sang de cordon définissent des subjectivités maternelles caractérisées par des obligations morales spécifiques.

La conservation autologue de sang de cordon ombilical : une ouverture sur une forme émergente de «citoyenneté biologique»

La transformation du sang de cordon ombilical en une précieuse source de cellules souches a, dès le début des années 1990, donné naissance à une industrie commerciale globale de conservation faisant désormais concurrence à un large réseau de conservation public. Ce mémoire cherche à comprendre et à expliquer les soubassements socio-culturels liés à l’émergence de cette industrie, ainsi qu’à mieux cerner les enjeux éthiques et politiques qu’elle pose. En exposant en premier lieu la manière dont les institutions publiques de conservation de sang de cordon se définissent, et sont généralement définies par les comités bioéthiques, comme étant porteuses des valeurs d’altruisme et de solidarité nationale traditionnellement liées au modèle « redistributif » d’échange de sang et d’organes né au lendemain de la Seconde Guerre mondiale, nous problématisons la manière innovatrice par laquelle les banques privées structurent le rapport entre les mères et leurs propres produits biologiques comme l’expression d’une reconfiguration du lien social et politique caractérisée par l’émergence de nouvelles socialisés. L’hypothèse au coeur de ce mémoire est que celles-ci peuvent être comprises comme l’aboutissant de l‘espoir collectivement partagé par les consommatrices d’améliorer leur propre condition biologique familiale, étant lui-même le fruit d’une financiarisation croissante des sciences du vivant. En analysant le discours « promissif » que représente le matériel promotionnel des banques autologues, notre objectif est alors d’identifier la manière par laquelle les multiples potentialités attribuées au sang de cordon définissent des subjectivités maternelles caractérisées par des obligations morales spécifiques.

Aspectos cognitivos en torno a la novela y el cine de la memoria histórica: "La voz dormida" de Dulce Chacón y su adaptación fílmica

Culture, history, and biology are inseparable. Cultural manifestations are necessarily immersed in a context, originate in the embodied minds that create them, and are directed to the embodied minds that receive them and recreate them within their contexts (individual and collective). The novel and the film of historical memory in Spain aim to connect their audiences with a problem that has not been solved, as the Civil War, the postwar, and the pact of forgetfulness left a wide sector of the Spanish society voiceless. During the last few years, a series of initiatives coming from the arts, as well as other realms such as the legal, have sought to reexamine the unhealed wound that still haunts Spanish subjects. La voz dormida [The Sleeping Voice] is one of those initiatives. It begins as testimony, develops into a hybrid and intertextual novel, and later becomes a film. It constitutes an inclusive project, one of offering an alternative version to the “official history”, while incorporating the marginal voices of women that had been left out of the memory of the war and the dictatorship. Objective and Results By examining both the literary and the cinematic versions of Chacón’s work I aimed to evidence the connections that exist between the artistic portrayal of the postwar repression (particularly how it affects women) and the current movement of recovery of historical memory in Spain. Specifically, I was interested in showing how both the novel and the film employ a series of narrative strategies that emphasize the body and intentionality, with the purpose of creating in readers and spectators an empathetic response that may lead to prosocial behavior. In order to carry out this interdisciplinary study, which relates fiction, mind, and socio-historical context, I draw on cognitive theories of literature and film, as well as theories from social and developmental psychology, such as the Richard Gerrig’s theory of narrative experience, Keith Oatley’s psychology of fiction, Suzanne Keen’s theory of narrative empathy, and the empathy-altruism hypothesis, derived form the ideas of Jean Decety, among others...

Agency theory and the family business

The conceptual domain of agency theory is one of the dominant organisational theory perspectives applied in current family business research (Chrisman et al., 2010). According to agency theory (Jensen and Meckling, 1976), agency costs generally arise due to individuals’ selfinterest and decision making based on rational thinking and oriented toward own preferences. With more people involved in decision making, such as through the separation of ownership and management, agency costs occur due to different preferences and information asymmetries between the owner (principal) and the employed management (agent) (Jensen and Meckling, 1976). In other words, agents take decisions based on their individual preferences (for example, short term, financial gains) instead of the owners’ preferences (for example, long term, sustainable development).

Charitable incentives for blood donation are promising, but require careful consideration

In outlining his proposal for a charitable incentive schemefor blood donors, Sass (2013) highlights the ongoing challengeof translating widespread public support for blooddonation into actual donors. Sass rightly points out that a reliableand effective blood supply depends on regular donations,rather than sporadic surges in response to exceptionalevents like September 11. He argues that prospective donorsmight be more effectively motivated to donate if each donationis rewarded or recognized with a financial contributionto public health care services or medical research. Sass anticipatessuch “health-related charitable incentives” wouldencourage prosocial behavior by enhancing the beneficialimpact of blood donation. The increased consequentialistvalue of each blood donation would strengthen preexistingprosocial motivations, and would augment the signalingvalue of donation as an altruistic activity. Unfortunately,Sass’s account of the donor–societal relationship is incomplete,due to his reliance on the traditional conception ofdonation as an act of unilateral altruism. He neglects to considerthe potential influence of reciprocity and solidarity inmotivating prosocial behavior and donation in particular(Sykora 2009), and the implications of these elements for ´his proposal. In this commentary, I outline a stronger argumentfor his charitable incentive proposal and discuss someof the potential concerns the proposal may raise.

Enacting the violent imaginary : reflections on the dynamics of nonviolence and violence in Buddhism

In this paper, I explore the complex ethical dynamics of violence and nonviolence in Mahāyāna Buddhism by considering some of the historical precedents and scriptural prescriptions that inform modern and contemporary Buddhist acts of self-immolation. Through considering these scripturally sanctioned Mahāyāna ‘case studies,’ the paper traces the tension that exists in Buddhist thought between violence and nonviolence, outlines the interplay of key Mahāyāna ideas of transcendence and altruism, and comments on the mimetic status and influence of spiritually charged texts. It is the contention of this paper that violent scriptural metaphors can create paradigms of enactment that are paradoxically illustrative of the core ‘non-violent’ Mahāyāna virtues of compassion (karuṇā), giving (dāna), patience (kṣānti), and vigor (vīrya). The discussion will show that these virtues are underpinned by the Mahāyāna philosophical mainstays of non-duality (advayavāda), bodhisattvic transcendent altruism, skillful means (upāya), and dependent co-origination (pratītyasamutpāda).

‘Sexurity’ and its effects in eastern Democratic Republic of Congo

Newly recognised as a threat to global peace and security, sexual violence in conflict is now a fixed item on international security agendas. This marks significant progress for women, gender equality and the integrity of peace programmes. Our aim here, however, is to reflect upon the risks that inhere in this accomplishment. Through the concept of ‘sexurity’, a tripartite amalgam of the securitisation of sexual violence, the sexualisation of security, and the language of crisis, we outline the adverse effects of tethering sexual violence to security. This article concerns itself with the material and symbolic effects of ‘sexurity’ for eastern Democratic Republic of Congo (DRC). It first outlines ‘sexurity’ and the context of its emergence before, drawing on fieldwork in eastern DRC, the second part underlines the effects of ‘sexurity’ for the country.

Love’s Calling How eroticism encourages religious intentions in "Joseph and Aseneth" and the "AEthiopika"

Ce mémoire s’intéresse à l’emploi de l’érotisme et de l’amour comme outils littéraires dans deux romans de l’Antiquité. Le texte principal est un écrit dérivé de la Torah intitulé Joseph et Aséneth. Le second est le roman grec d’Héliodore d’Émèse, Les Éthiopiques. Puisque tout auteur, peu importe sa foi, avait une éducation hellénique semblable, on retrouve des motifs similaires dont les détails se distinguent et les buts sont aux antipodes dans ces textes. Dans le cas de cette recherche, il s’agit de deux oeuvres du genre romanesque écrites en grec qui emploient chacune une histoire romantique à des fins édifiantes. Les buts de cette analyse sont triples. Ce travail cherche à montrer que Joseph et Aseneth a droit au titre de « roman grec, » de qualifier les expériences religieuses présentées dans ces oeuvres et de participer au débat sur la datation de Joseph et Aseneth par une étude comparée. Cette recherche se divise en trois sections. D’abord, le topos bien connu des romans a été analysé : la maladie d’amour. Dans les deux cas, le coup de foudre et la maladie émotionnelle qui s’en suit ont été dévoilés comme moteur important de la trame narrative, ainsi qu’une manière d’introduire des thèmes religieux ou philosophiques. En second lieu, les paroles des personnages au sujet de l’amour et le mariage ont été considérées. Puisque les protagonistes refusent le mariage initialement, les raisons données pour ce refus ont été révélatrices encore une fois de soucis sociaux, soit religieux, soit politiques. En dernier lieu, la relation entre le couple romantique et les dieux présents dans ces récits a été analysée. Les deux romans témoignent de la croyance contemporaine du grand rôle des dieux dans la vie des humains. Cette implication divine dans la vie mortelle s’est manifestée de manières différentes, car elle relève des buts divergents des deux romans. Le parallèle qui se présente est un lien individuel avec les dieux qui est évident dans les romans d’amour.

El papel de la cooperación sur-sur en materia de educación técnica en Haití después del terremoto del 2010: estudio de caso: Brasil y Ecuador (2010-2015)

El presente estudio de caso analiza el papel de la Cooperación Sur-Sur (CSS) proveída por Brasil y Ecuador en materia de Educación Técnica en Haití después del terremoto del 2010 hasta el año 2015. Bajo el entendido que la CSS busca intercambiar, por medio de proyectos, los conocimientos y técnicas en los cuales estos países tienen experiencia, una de las formas de cooperación que tienen Brasil y Ecuador frente a Haití está basada en brindar capacidades en materia de Educación Técnica, con el fin de incentivar el desarrollo del recurso humano en los diferentes sectores a los cuales ésta va dirigida. En ese sentido, se escogieron dichos países al ser dos de los que más aportaron de América del Sur mediante la Educación Técnica hacia Haití después del terremoto. De ésta forma queda demostrado que por medio del intercambio de conocimientos, se puede hacer una apuesta fundamental al desarrollo de un país, enseñando y capacitando a personal de áreas específicas, con el ánimo de aumentar las capacidades productivas.

Actitudes hacia la Enfermedad del Alzheimer según el género y la edad de adultos colombianos

La enfermedad de Alzheimer (EA) es la demencia más frecuente y su prevalencia continúa en aumento tanto en Colombia como en el mundo. Esta investigación tuvo como objetivo explorar si las actitudes hacia la EA varían según la edad y género de 450 personas adultas colombianas. Se realizó un estudio exploratorio de corte transversal en el que se aplicó un cuestionario autodiligenciado. Se encontró que efectivamente hay algunas diferencias según la edad y el género en el componente cognoscitivo (creencias y conocimiento) y conductual (intención conductual y conducta) de las actitudes; y diferencias según el género en el componente afectivo. Se concluye que los conocimientos sobre la EA son escasos, que la tristeza es la emoción predominante hacia la EA y que es un tema de interés en el que predomina la idea de que afecta especialmente la memoria. Se discutieron los resultados reconociendo que esta es una aproximación inicial a las actitudes hacia la EA.

Innovación social: una reflexión sobre los beneficios en su implementación en el Estado colombiano.

La innovación social es un tipo de innovación que promueve la búsqueda de soluciones enfocadas a los problemas que se presentan en la sociedad. Estas soluciones generan además un valor agregado que ayudan al crecimiento del país. En Colombia este tipo de iniciativas han empezado a tener una gran importancia y han empezado a promover condiciones de vida más favorables y justas que buscan generar un beneficio a la sociedad y contribuir al desarrollo del país. A partir de la historia de la innovación social, ejemplos y grandes literatos en la administración y la sociología, comprenderemos la importancia de la innovación en nuestro país.