Judaização da Palestina ocupada: colonização, desapropriação e deslocamento em Jerusalém Oriental, Cisjordânia e Faixa de Gaza entre 1967 e 2013

Pós-graduação em Relações Internacionais (UNESP - UNICAMP - PUC-SP) - FFC

Os movimentos nas redes e em redes: das manifestações internacionais ao Movimento Prudente

Neste trabalho apresentamos uma leitura sobre o processo de articulação dos movimentos em redes e do uso das redes sociais pelos movimentos socioespaciais que mais se destacaram no mundo nos últimos cinco anos. Tendo suas bases nos marcos conceituais de movimentos socioespacial, movimentos socioterritorial, Rede e Redes Sociais, remontamos ao processo de formação da Via Campesina e das manifestações na Primavera Árabe, M12M, M15M, Occupy Wall Street, Movimento Passe Livre e o Movimento Prudente na escala local. Analisar e comparar estes movimentos e suas manifestações nos permitiu identificar a conexão entre a difusão de informações nas redes sociais e a materialização das manifestações no espaço público. Destaca-se que o uso destas tem acarretado em uma nova dinâmica não só na difusão de manifestação, mas também na realização de trabalho de base, caracterizando-se como um importante espaço de socialização política da atualidade

Alterações no equilíbrio ácido-base em equinos submetidos à prova de três tambores ou à competição de enduro de 160 Km

Pós-graduação em Medicina Veterinária - FCAV

Literaturas magrebinas de expressão francesa: o desafio identitário de traduzir o(s) outro(s)

A interrogação sobre o estatuto da língua na qual se escreve é um imperativo para os escritores dos chamados “espaços excêntricos” divididos entre a herança da língua do colonizador e a diversidade dos múltiplos idiomas locais. Escrever nesse contexto é travar um enfrentamento direto com questão da língua, visto que o escritor estabelece com a “língua literária”, que nem sempre é sua língua materna nem sua língua nacional, relações extremamente complexas. No caso específico dos escritores magrebinos de língua francesa, podemos afirmar que suas escritas literárias funcionam como uma espécie de tradução do mundo árabe no Ocidente, como uma mise-en-scène escritural na tentativa de resgatar o passado colonial, as dilacerações subjetivas e as rupturas identitárias. Desta forma, a partir da análise da obra La mémoire tatouée: autobiographie d’un décolonisé (1971), do escritor marroquino AbdelKebir Khatibi, procuraremos mostrar como as questões políticas e identitárias inscrevem-se na tessitura do literário com o intuito de traduzir o outro numa dimensão que ultrapassa os efeitos de ordem linguística para se configurarem como um ato de tradução entre as culturas, os povos e, como diria Khatibi, entre as espiritualidades.

Paródia e ironia em moralités légendaires de jules laforgue

Jules Laforgue is a French Symbolist poet, he wrote poetry works such as Les complaintes, L’imitation de Notre-Dame, la lune, Le sanglot de la terre. In spite of mostly of symbolist poets write only poetry, he also dedicated himself to prose works such as Moralités Légendaires, a particular work in prose and extreme today as in the nineteenth century, he devoted himself to parody and irony. The novels that make up this book are the work of writing and tone of nuance. They refer to literary genres, without, however, respect their definitions. There are demarcation of famous texts, but that refer more to modes, themes, and aesthetic conventions. Here, the poet makes variations on familiar themes, and explore his Moralités arguments that belong to a cultural background: the myth of Hamlet, approached the novel here mentioned belong to a cultural heritage that an author set for posterity. In other novels, the author makes use of myths Greco-Latin and Judeo-Christian myths rewriting so parodic, ironic, looking for originality, doing the work of Symbolist and modern poet.

Administração de maltodextrina em cavalos submetidos a teste de exercício progressivo e a exercícios sequenciais de alta intensidade e curta duração em esteira

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Determinações estratégicas e econômicas da dominação britânica no Egito (1804-1956)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Clinical characteristics and possible phenotypes of an adult severe asthma population

Background: Currently, there are no studies of well-characterized severe asthmatics in Brazil. We aimed to study a population of severe treated asthmatics still uncontrolled to characterize them and define possible phenotypes. Methods: Descriptive cross-sectional outpatient study of severe asthmatics, evaluating functional and inflammatory markers, health-related quality of life, anxiety and depression symptoms, clinical control status, and characteristics related to atopy, age of asthma onset, induced sputum eosinophil levels, and airflow limitation. We also grouped the subgroups characteristics to identify phenotypes. The study is registered on ClinicalTrial.gov NCT 01089322. Results: From 128 eligible patients with severe/uncontrolled asthma, 74 fulfilled the inclusion criteria. The cohort was comprised of 85% women, frequently with a body mass index higher than 31 kg m(-2), atopy (60%), early-onset disease (50%), sputum eosinophilia (80%), comorbidities, and reduced quality of life. Nonatopics had significant higher asthma onset (19 y.a.) and twice level of induced sputum eosinophil. Late-onset patients had significantly less atopy (57%) and higher levels of induced sputum eosinophils. Non-eosinophilics had lower levels of inflammatory markers. Patients with airflow limitation had more intensive care unit admissions (56%) and 1.5 times more airway resistance. Subgroups characteristics identified a priori four well-characterized phenotypes, with 55% presenting sputum eosinophilia. Conclusion: Our data emphasize the high burden of disease, the persistence of inflammation and the existence of clinical possible phenotypes population sharing common features with published cohorts. Despite the necessity of further investigation into pathogenic mechanisms, this study with clinically difficult patient group may help to improve future asthma care. (C) 2011 Elsevier Ltd. All rights reserved.

Extracellular matrix composition in COPD

Extracellular matrix (ECM) composition has an important role in determining airway structure. We postulated that ECM lung composition of chronic obstructive pulmonary disease (COPD) patients differs from that observed in smoking and nonsmoking subjects without airflow obstruction. We determined the fractional areas of elastic fibres, type-I, -III and -IV collagen, versican, decorin, biglycan, lumican, fibronectin and tenascin in different compartments of the large and small airways and lung parenchyma in 26 COPD patients, 26 smokers without COPD and 16 nonsmoking control subjects. The fractional area of elastic fibres was higher in non-obstructed smokers than in COPD and nonsmoking controls, in all lung compartments. Type-I collagen fractional area was lower in the large and small airways of COPD patients and in the small airways of non-obstructed smokers than in nonsmokers. Compared with nonsmokers, COPD patients had lower versican fractional area in the parenchyma, higher fibronectin fractional area in small airways and higher tenascin fractional area in large and small airways compartments. In COPD patients, significant correlations were found between elastic fibres and fibronectin and lung function parameters. Alterations of the major ECM components are widespread in all lung compartments of patients with COPD and may contribute to persistent airflow obstruction.

History and Epistemology of Science in the Classroom: The Synthesis of Quinine as a Proposal

The history of the quinine synthesis can be used as a case study to emphasize that science is influenced by social and historical processes. The first efforts toward the synthesis of this substance, which until recently was the only treatment for malaria, were by Perkin in 1856 when, trying to obtain quinine,,. he synthesized mauveine. Since then, the quest for the total synthesis of quinine involved several characters in a web of controversies. A major step in this process was made in 1918 by Rabe and Kindler, who proposed the synthesis of quinine from quinotoxine. Twenty-six years later, after obtaining the total synthesis of quinotoxine, Woodward and Doering announced the total synthesis of quinine. However, the lack of experimental details about Rabe and Kindler's process, associated with Woodward and Doering's failure to reproduce it, raised a series of doubts about the synthesis. Stork and colleagues questioned the veracity of the experimental data and even the scientific reputation of the involved researchers. Doubts remained alive until 2008, when Williams and Smith reported, not without reservations, the reproducibility of Rabe and Kindler's protocol. The scientific knowledge as a social and historical development, its legitimating process, and the absence of neutrality in science constitute aspects that can be discussed from this case study, providing significant contributions to science education, in particular, to the initial or continued training of chemistry teachers.

Smoking cessation and bronchial epithelial remodelling in COPD: a cross-sectional study

Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is associated with bronchial epithelial changes, including squamous cell metaplasia and goblet cell hyperplasia. These features are partially attributed to activation of the epidermal growth factor receptor (EGFR). Whereas smoking cessation reduces respiratory symptoms and lung function decline in COPD, inflammation persists. We determined epithelial proliferation and composition in bronchial biopsies from current and ex-smokers with COPD, and its relation to duration of smoking cessation. Methods 114 COPD patients were studied cross-sectionally: 99 males/15 females, age 62 ± 8 years, median 42 pack-years, no corticosteroids, current (n = 72) or ex-smokers (n = 42, median cessation duration 3.5 years), postbronchodilator FEV1 63 ± 9% predicted. Squamous cell metaplasia (%), goblet cell (PAS/Alcian Blue+) area (%), proliferating (Ki-67+) cell numbers (/mm basement membrane), and EGFR expression (%) were measured in intact epithelium of bronchial biopsies. Results Ex-smokers with COPD had significantly less epithelial squamous cell metaplasia, proliferating cell numbers, and a trend towards reduced goblet cell area than current smokers with COPD (p = 0.025, p = 0.001, p = 0.081, respectively), but no significant difference in EGFR expression. Epithelial features were not different between short-term quitters (<3.5 years) and current smokers. Long-term quitters (≥3.5 years) had less goblet cell area than both current smokers and short-term quitters (medians: 7.9% vs. 14.4%, p = 0.005; 7.9% vs. 13.5%, p = 0.008; respectively), and less proliferating cell numbers than current smokers (2.8% vs. 18.6%, p < 0.001). Conclusion Ex-smokers with COPD had less bronchial epithelial remodelling than current smokers, which was only observed after long-term smoking cessation (>3.5 years). Trial registration NCT00158847

Concentração plasmática de cortisol decorrente do exercício físico em cavalos de enduro

O objetivo deste trabalho foi relacionar a intensidade do exercício físico e as concentrações de cortisol plasmático em cavalos de enduro, uma competição em que somente animais experientes podem competir nas provas mais longas. Foram utilizados 30 equinos Puro Sangue Árabe e mestiços Árabe, machos ou fêmeas participantes de provas de enduro. Foram divididos em três grupos de 10 animais: (G1): percorreram mais de 100km, (G2): percorreram menos de 100km, e (G3): desqualificados por causa metabólica. Foram realizadas dosagens de cortisol plasmático em três momentos diferentes: (t0): dia anterior à competição, (t1): 30 a 60 minutos após o término da prova e, (t2): 90 a 120 minutos após o término da prova. Concluiu-se que o enduro leva ao aumento do cortisol plasmático; animais que percorrem maiores distâncias apresentam menor aumento das concentrações de cortisol; animais desqualificados por causa metabólica, que passam por situações de extremo esforço físico, tendem a valores de cortisol mais elevados e animais menos experientes apresentam valores de cortisol mais elevados mesmo tendo percorrido menores distâncias.

Metáteses árabes da metáfora: desvelar/velar

Um dos mais intrigantes fatos semânticos da língua árabe é a metátese, transposição de fonemas dentro de uma palavra, frequentemente com relação de sentido entre as formas metatéticas. Em m-th-l, a raiz triconsonantal para a palavra “metáfora”, as metáteses são imensamente sugestivas: Th-L-M and L- Th-M; a ambígua função da metáfora: mostrar e ocultar. A partir desse fato, o artigo discute esses aspectos da metáfora