999 resultados para Autismo em crianças - Aspectos genéticos
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O câncer tem sido alvo de incessantes pesquisas sobre sua etiologia, desenvolvimento, progresso e tratamentos. Sua importância no campo científico se dá pela sua alta taxa de mortalidade e morbidade. O fato de que seja uma doença genética, que pode ter interferência ambiental e dietética, está cada vez mais elucidado, porém ainda existem muitos mecanismos a serem desvendados. As neoplasias ósseas, benignas ou malignas, e processos inflamatórios ósseos acometem desde crianças até adultos e idosos, podendo causar danos físicos, incapacidade motora e até a morte. Portanto, presumir o potencial de transformação maligna das lesões benignas, agressividade tumoral, capacidade de invasão tecidual, probabilidade de recidiva, propensão ao desenvolvimento de metástases e resposta ao tratamento, é um valioso expediente na escolha da proposta terapêutica. Estudos genéticos e citogenéticos têm ajudado a aumentar o entendimento sobre a carcinogênese, progressão tumoral, prognósticos e diagnósticos. Portanto, este estudo teve como objetivo detectar mutações e marcadores cromossômicos consistentes e recorrentes na transformação de tumores benignos em malignos no sistema musculoesquelético, através de análises com citogenética clássica, e relacionar estes achados com o prognóstico e diagnóstico dos pacientes. Dentre os casos coletados e analisados citogeneticamente, foram selecionados três casos de lesões ósseas benignas e três lesões ósseas malignas tidas como a progressão tumoral dos respectivos casos benignos, para discussão e relato de caso. Os achados citogenéticos relataram consistentes alterações numéricas e estruturais clonais em regiões cromossômicas com genes importantes envolvidos na progressão tumoral. Pode-se citar a perda da região contendo o gene TP53, supressor tumoral, tanto em lesões benignas como em maligna, como um dos achados mais relevantes neste estudo. Dessa forma, os resultados ...
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This study was performed as a requirement of the final course in Nursing. The study is cross-cutting, in order to identify associations between socioeconomic factors, education, child hospitalization in the ICU or not, degree of depression and level of social support (material, affective, emotional, informational and positive social interaction) and how to identify subgroups of mother - child vulnerable. Constitute themselves as subjects, mothers of children 0 to 17 years, 11 months and 29 days in hospital after the second day of hospitalization in the pediatric unit of a State Hospital Interior Paulista. Data collection was initiated after obtaining the assent of the Research Ethics Committee, as well as signing the consent form. We used the following instruments to collect data: the data form for socioeconomic and hospitalization; Beck Depression Inventory and Medical Outcomes Study (MOS). We obtained the result that there is a strong association between availability and social support and income per capita and the degree of depression, but did not find an association between time and hospital stay and whether the child was admitted to the ICU or not. We conclude that it is necessary to establish treatment services from the patient’s family, plus an appropriate social service support to meet this big demand for mothers who need support
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It is through the media that information is transmitted, both educational or noneducational. Among the various forms of media there’s television, as one of the means of communication most used since the 50’s. Most of the time, television displays images and words to reach the target audience, something that is done in a simple, but often appealing way. Media is present in our daily lives and takes a significant educational role in the constitution of subjects. That is to say, the persuasive power of television is amazing, in order to influence children in their habits and their ways of thinking and acting. It was intended to discuss in this paper the influence of media on kindergarten children. For this, the historic rescue of television in Brazil was presented and also its trajectory to the present day and the power of media on children in preschool
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O objetivo deste artigo é discutir aspectos enunciativos em reconto infantil produzido por crianças na faixa etária de 07 a 09 anos, em contexto escolar, em suportes distintos, a saber, no papel e na tela do computador com acesso à internet. De um ponto de vista teórico, que privilegia estudos da Enunciação e do Discurso (BAKHTIN, 1997; CORRÊA, 2004), procura-se refletir sobre modificações no texto/discurso dada a mudança do suporte material, segundo a hipótese de que, ao enunciar no papel ou na tela, as diferentes projeções que o escrevente faz da imagem do outro, da de si próprio e da dos suportes utilizados no processo de textualização podem ser investigadas na relação sujeito-linguagem. Metodologicamente, este trabalho apoia-se no paradigma indiciário, o qual permite conceber fenômenos da linguagem como indícios representativos de fenômenos mais gerais. A análise, de cunho qualitativo-interpretativo, privilegia, portanto, o estudo de marcas linguísticas que indiciam diferentes projeções de imagens que os escreventes produzem com diferentes interlocutores em suportes distintos.
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Pós-graduação em Saúde Coletiva - FMB
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Pós-graduação em Odontologia Preventiva e Social - FOA
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Pós-graduação em Ciência Odontólogica - FOA
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Pós-graduação em Saúde Coletiva - FMB
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As alterações que afetam as hemoglobinas estão relacionadas à síntese estrutural ou quantitativa dos aminoácidos que compõem as diferentes cadeias globínicas (α/β). Existem inúmeras causas que podem resultar nessas alterações, dentre elas as mutações. A talassemia é um dos distúrbios genéticos mais frequentes do homem e mais difundidos no mundo. Fatos históricos, como imigração e colonização populacionais de diferentes partes do mundo, contribuíram para a difusão da patologia em outras localidades, incluindo o Brasil. A forma de manifestação clínica e laboratorial da talassemia do tipo beta menor (BTT), foi objeto de estudo nesta revisão bibliográfica, pois embora seja uma patologia que não mostra claramente manifestações sintomáticas, seus aspectos clínicos e laboratoriais são muito relevantes. A importância do diagnóstico laboratorial das anemias microcíticas e hipocrômicas presentes, tanto em indivíduos portadores de deficiência de ferro como em beta talassêmicos menor, é um ponto chave quando nos referimos a esses parâmetros, pois os índices HCM e VCM apresentam-se com valores extremamente reduzidos (<24 pg e <70 fL) e a quantidade de glóbulos vermelhos muito aumentados (> 5,0 milhões/μL), na beta talassemia menor em comparação à deficiência de ferro. Portanto os valores contidos no hemograma bem como a presença da inclusão citoplasmática ponteado basófilo e morfologia das hemácias observadas em análise de extensões sanguíneas coradas, é de grande valia na suspeita da beta talassemia menor, tornando-se ponto importante na sugestão da realização de eletroforese de hemoglobina para confirmação do diagnóstico da beta talassemia menor, devido ao aumento quantitativo da Hb A2.
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School and family are critical contexts to the development of concepts in childhood and few studies are conducted from the report of children when they live in rest-home. The aim of this study was to investigate concepts that children in rest-homes have about school and gender. There were 22 participants, including boys and girls, between 4 and 6 years, who were interviewed with open questions for content analysis. For these children the school was associated with an area of study opportunities, favorable to themselves, although by necessity or obligation, and possibly with the presence of conflicts. The gender was described from biological and psychosocial aspects and children attributed their gender identity at destination, learning and social advantages. Children feel they belong to a gender in a positive way, although by attributing disadvantages to the opposite gender, for example, relating male aggression to violence. Children reproduce some patterns and social characteristics of gender that probably were learned in different contexts. We conclude that studies in this area are important to identify children´s conceptions about school and sexuality, their roles and representations, especially when they live in an environment with such specific features as a rest-home.
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This article presents part of a study that analyzed the concepts, feelings and attitudes of children without disabilities about mental retardation and inclusion and evaluated the effects of an informative program that deals with the issue. The study included forty children from two first grade classrooms in a public school in Marília-SP. One classroom participated as a control group. All children underwent pre and post tests in the form of interviews on the subject and a scale of children's social attitudes towards inclusion was applied. The experimental group participated in the informative program, composed of thirteen weekly meetings, in which the limitations and possibilities of people with mental retardation, specialized care, their schooling and family and social aspects, were discussed, using various educational and recreational strategies. The data collected in the interviews were categorized and content analysis was conducted. With the scale, individual scores were obtained. Statistical calculations were performed to verify the significance of differences between groups. In this paper we discuss the data obtained with the scale which were crossed with interview data. The results of the interviews and the scale indicated several changes in children's attitudes towards inclusion, but relations between many of these data could not be statistically confirmed. These results indicate the importance of expanding the research on the relationship between the phenomena presented.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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This paper is the result of a homonymous scientific research, funded by CNPq-PIBIC where we understand the adoption process as a process of dissidence in relation to the bio-parental matrix. Founded on a heteronormative naturalization of human sexuality - which presupposes a continuum and naturalized organization among sex / gender / desire – this bioparental matrix sets the binary relation of distinction between the legitimate/illegitimate child as their origin or not arising from “blood ties”. Considering our experience in the Project developed at the Department of Clinical Psychology at UNESP, Assis, SP called “Ties of love: Adoption, Gender, Citizenship and Rights”, we prepared a content analysis - as proposed by Bardin (1977) -, of transcripts of psychological sessions that were made from 2005 to 2012 in the "Center for Research and Applied Psychology “Dra. Betti Katzenstein. Our general objective was to analyze the effects of the bioparental matrix and its impact on children/adolescents and their families as well as estimate the possibilities of escape to the subjection to this bioparental matrix. The results showed us several aspects that may be significant for understanding the discursive crossings related to the practice of adoption. It was observed that there is still a great ambivalence pervading this theme, revealing that there is a discrepancy between what we say and what we do in relation to practices of caring among the adopted children. On the one hand, it was noticed that relatives rationally seek to enhance the bonding of the “emotional ties”, but their practices and beliefs, are still supported in modes of subjectivation that prioritize the biological discourse. This fact reveals a strained and conflictive field that probably weaknesses those families seeking to prioritize the ties of affection. However, as can be seen in this study, it is comforting and motivating to realize the power of resistance of individuals to absolute truths that govern their ways of feeling, affiliating and/ or exert their parenting.
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Pós-graduação em Direito - FCHS
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Pós-graduação em Ciências Sociais - FFC